Clinical Pharmacology and Therapeutics - Table of Contents alert Volume 94 Issue 1

Advertisement Webinar on high throughput pharmacogenetic analysis of key ADME/T biomarkers • Wednesday June 26. • Register now for : 8AM PST or  4PM PST • Measurement, analysis and reporting of SNPs, INDELs and CNVs in 36 key genes related to ADME/T including CYP2C9, CYP2C19, CYP2D6, and UGT1A1  TABLE OF CONTENTS Volume 94, Issue 1 (July 2013) In this issue In This Issue Editorial News & Views Perspectives Discovery Development State of the Art Reviews Research Sign up for CPT: Pharmacometrics & Systems Pharmacology e-alerts Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement FREE WEB COLLECTION: Heart Failure Therapies  This Nature Reviews Cardiology collection examines available and novel therapies for heart failure, a common, costly, debilitating, and potentially lethal condition that affects up to 20% of adults during their lifetime. The six Review articles have been written by leading experts in the field. FREE online for a limited time. In This Issue Top In This Issue Clin Pharmacol Ther 2013 94: 1; 10.1038/clpt.2013.98 Full Text Editorial Top Transporters in Drug Development and Clinical Pharmacology K M Giacomini and S-M Huang Clin Pharmacol Ther 2013 94: 3-9; 10.1038/clpt.2013.86 Abstract | Full Text News & Views Top HIGHLIGHTS Clin Pharmacol Ther 2013 94: 10-11; 10.1038/clpt.2013.97 Full Text ASCPT NEWS Clin Pharmacol Ther 2013 94: 12-17; 10.1038/clpt.2013.87 Full Text Perspectives Top COMMENTARIES SLC Classification: An Update A Schlessinger, S W Yee, A Sali and K M Giacomini Clin Pharmacol Ther 2013 94: 19-23; 10.1038/clpt.2013.73 Abstract | Full Text International Transporter Consortium Commentary on Clinically Important Transporter Polymorphisms K M Giacomini, P V Balimane, S K Cho, M Eadon, T Edeki, K M Hillgren, S-M Huang, Y Sugiyama, D Weitz, Y Wen, C Q Xia, S W Yee, H Zimdahl and M Niemi ; on behalf of the International Transporter Consortium Clin Pharmacol Ther 2013 94: 23-26; 10.1038/clpt.2013.12 Abstract | Full Text How Much Do We Know About Drug Handling by SLC and ABC Drug Transporters in Children? S K Nigam and V Bhatnagar Clin Pharmacol Ther 2013 94: 27-29; 10.1038/clpt.2013.82 Abstract | Full Text Discovery Top Computational Prospecting for Drug–Transporter Interactions P Matsson and P Artursson Clin Pharmacol Ther 2013 94: 30-32; advance online publication, April 2, 2013; 10.1038/clpt.2013.67 Full Text Development Top Imaging in the Study of Membrane Transporters H Kusuhara Clin Pharmacol Ther 2013 94: 33-36; advance online publication, April 24, 2013; 10.1038/clpt.2013.85 Full Text State of the Art Top Ethnic Variability in the Plasma Exposures of OATP1B1 Substrates Such as HMG-CoA Reductase Inhibitors: A Kinetic Consideration of Its Mechanism Y Tomita, K Maeda and Y Sugiyama Clin Pharmacol Ther 2013 94: 37-51; advance online publication, November 7, 2012; 10.1038/clpt.2012.221 Abstract | Full Text Emerging Transporters of Clinical Importance: An Update From the International Transporter Consortium K M Hillgren, D Keppler, A A Zur, K M Giacomini, B Stieger, C E Cass and L Zhang ; on behalf of the International Transporter Consortium Clin Pharmacol Ther 2013 94: 52-63; advance online publication, April 8, 2013; 10.1038/clpt.2013.74 Abstract | Full Text Reviews Top ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans M J Zamek-Gliszczynski, C A Lee, A Poirier, J Bentz, X Chu, H Ellens, T Ishikawa, M Jamei, J C Kalvass, S Nagar, K S Pang, K Korzekwa, P W Swaan, M E Taub, P Zhao and A Galetin ; on behalf of the International Transporter Consortium Clin Pharmacol Ther 2013 94: 64-79; advance online publication, February 25, 2013; 10.1038/clpt.2013.45 Abstract | Full Text Why Clinical Modulation of Efflux Transport at the Human Blood–Brain Barrier Is Unlikely: The ITC Evidence-Based Position J C Kalvass, J W Polli, D L Bourdet, B Feng, S-M Huang, X Liu, Q R Smith, L K Zhang and M J Zamek-Gliszczynski ; on behalf of the International Transporter Consortium Clin Pharmacol Ther 2013 94: 80-94; advance online publication, February 14, 2013; 10.1038/clpt.2013.34 Abstract | Full Text In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development K L R Brouwer, D Keppler, K A Hoffmaster, D A J Bow, Y Cheng, Y Lai, J E Palm, B Stieger and R Evers ; on behalf of the International Transporter Consortium Clin Pharmacol Ther 2013 94: 95-112; advance online publication, April 10, 2013; 10.1038/clpt.2013.81 Abstract | Full Text Transporter Studies in Drug Development: Experience to Date and Follow-Up on Decision Trees From the International Transporter Consortium D Tweedie, J W Polli, E Gil Berglund, S M Huang, L Zhang, A Poirier, X Chu and B Feng ; On Behalf of the International Transporter Consortium Clin Pharmacol Ther 2013 94: 113-125; advance online publication, April 10, 2013; 10.1038/clpt.2013.77 Abstract | Full Text Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver X Chu, K Korzekwa, R Elsby, K Fenner, A Galetin, Y Lai, P Matsson, A Moss, S Nagar, G R Rosania, J P F Bai, J W Polli, Y Sugiyama and K L R Brouwer ; on behalf of the International Transporter Consortium Clin Pharmacol Ther 2013 94: 126-141; advance online publication, April 10, 2013; 10.1038/clpt.2013.78 Abstract | Full Text Research Top ARTICLES HLA-A*31:01 and HLA-B*15:02 as Genetic Markers for Carbamazepine Hypersensitivity in Children U Amstutz, C J D Ross, L I Castro-Pastrana, M J Rieder, N H Shear, M R Hayden, B C Carleton and the CPNDS Consortium Clin Pharmacol Ther 2013 94: 142-149; advance online publication, March 18, 2013; 10.1038/clpt.2013.55 Abstract | Full Text Hematopoietic Stem and Progenitor Cell Mobilization in Mice and Humans by a First-in-Class Mirror-Image Oligonucleotide Inhibitor of CXCL12 Open A Vater, J Sahlmann, N Kröger, S Zöllner, M Lioznov, C Maasch, K Buchner, D Vossmeyer, F Schwoebel, W G Purschke, S Vonhoff, A Kruschinski, K Hübel, M Humphrey, S Klussmann and F Fliegert Clin Pharmacol Ther 2013 94: 150-157; advance online publication, March 19, 2013; 10.1038/clpt.2013.58 Abstract | Full Text A DPYD Variant (Y186C) in Individuals of African Ancestry Is Associated With Reduced DPD Enzyme Activity S M Offer, A M Lee, L K Mattison, C Fossum, N J Wegner and R B Diasio Clin Pharmacol Ther 2013 94: 158-166; advance online publication, April 3, 2013; 10.1038/clpt.2013.69 Abstract | Full Text Advertisement New content available each week!  Original Research - Reviews & Perspectives - Tutorials CPT: PSP publishes critical content covering the latest advances in quantitative methods as applied in pharmacology, physiology, and therapeutics in humans with a common focus on the application of these two areas on drug development. CPT: PSP is an online open access journal.      Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Clinical Pharmacology & Therapeutics. In order to do so, please purchase a subscription. You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. For other enquiries, please contact our customer feedback department. Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2013 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.