The EMBO Journal - Table of Contents alert Volume 32 Issue 4

TABLE OF CONTENTS 20 February 2013 | Volume 32, Issue 4 Have you seen? Articles Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement The EMBO Journal Editor's choice: Immunology RIG-I-mediated sensing of Listeria nucleic acids Abdullah, Knolle and colleagues BRG1 mediated Treg activation in immune tolerance Chaiyachati, Chi and colleagues Alarmin Mrp8/14 regulates adaptive immunity in dermatitis Petersen, Vogl and colleagues   Have you seen? Top Lateral thinking: CaMKII uncouples kainate receptors from mossy fibre synapses Activation of CaMKII induces long-term depression at the hippocampal mossy fibre synapse by promoting lateral diffusion of kainate receptors out of the synapse to fine-tune synaptic plasticity. Bryan A Copits and Geoffrey T Swanson The EMBO Journal (2013), 32, 487 - 489; 10.1038/emboj.2013.12 Abstract | Full text | PDF | Related article Published online: 29 January 2013 Running a little late: chloroplast Fe status and the circadian clock Iron homeostasis is essential for plant growth and survival. Two papers now report that chloroplast Iron levels also regulate the period of the circadian clock, which might confer fitness advantage by linking iron status to daily changes in environmental conditions. Grandon T Wilson and Erin L Connolly The EMBO Journal (2013), 32, 490 - 492; 10.1038/emboj.2013.14 Abstract | Full text | PDF | Related article Published online: 01 February 2013 Early replication fragile sites: where replication–transcription collisions cause genetic instability Groundbreaking work reported by Barlow et al in Cell identifies a new class of fragile sites as a source of genomic rearrangements in cancer. Oliver Mortusewicz, Patrick Herr and Thomas Helleday The EMBO Journal (2013), 32, 493 - 495; 10.1038/emboj.2013.20 Abstract | Full text | PDF | Related article Published online: 01 February 2013 Articles Top CaMKII-dependent phosphorylation of GluK5 mediates plasticity of kainate receptors CamKII governs long-term depression of kainate receptor (KAR) synaptic currents by phosphorylating the subunit GluK5, increasing its mobility and diffusion away from synaptic sites. Mario Carta, Patrizio Opazo, Julien Veran, Axel Athané, Daniel Choquet, Françoise Coussen and Christophe Mulle The EMBO Journal (2013), 32, 496 - 510; 10.1038/emboj.2012.334 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 04 January 2013 Subject Categories: Neuroscience Circadian clock adjustment to plant iron status depends on chloroplast and phytochrome function  EMBO Open The circadian clock of Arabidopsis is found to be hardwired to cellular iron levels, with chloroplasts playing a central role in iron sensing. Patrice A Salomé, Michele Oliva, Detlef Weigel and Ute Krämer The EMBO Journal (2013), 32, 511 - 523; 10.1038/emboj.2012.330 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 14 December 2012 Subject Categories: Signal Transduction | Plant Biology Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation The endosomal E3 ligases Godzilla and Goliath ubiquitinate the SNARE protein VAMP3 and thereby govern endosomal trafficking. Yasuo Yamazaki, Christina Schönherr, Gaurav K Varshney, Murat Dogru, Bengt Hallberg and Ruth H Palmer The EMBO Journal (2013), 32, 524 - 537; 10.1038/emboj.2013.1 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 25 January 2013 Subject Categories: Membranes and Transport | Proteins Structure-based in silico identification of ubiquitin-binding domains provides insights into the ALIX-V:ubiquitin complex and retrovirus budding A structure database mining approach not only reveals potential new ubiquitin-binding domains, but also immediately suggests the molecular basis of their interactions. Tal Keren-Kaplan, Ilan Attali, Michael Estrin, Lillian S Kuo, Efrat Farkash, Moran Jerabek-Willemsen, Noa Blutraich, Shay Artzi, Aviyah Peri, Eric O Freed, Haim J Wolfson and Gali Prag The EMBO Journal (2013), 32, 538 - 551; 10.1038/emboj.2013.4 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 29 January 2013 Subject Categories: Proteins | Genomic and Computational Biology Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? Purified 26S proteasomes equally degrade substrates bearing K48- and K63-linked ubiquitin chains, but cellular ubiquitin binding proteins selectively block proteasome targeting of K63-linked chains. James A Nathan, Hyoung Tae Kim, Lily Ting, Steven P Gygi and Alfred L Goldberg The EMBO Journal (2013), 32, 552 - 565; 10.1038/emboj.2012.354 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 11 January 2013 Subject Categories: Proteins TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3 A new ATG16L1-binding motif identified in several innate immune response proteins is involved in a non-classical form of autophagy in response to bacterial infection. Emilio Boada-Romero, Michal Letek, Aarne Fleischer, Kathrin Pallauf, Cristina Ramón-Barros and Felipe X Pimentel-Muiños The EMBO Journal (2013), 32, 566 - 582; 10.1038/emboj.2013.8 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 01 February 2013 Subject Categories: Differentiation and Death | Microbiology and Pathogens IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production IRAK-M was reported to inhibit TLR signalling. Now, IRAK-M is shown to activate NFκB via interaction with MyD88/IRAK-4 leading to the induction of a negative feedback loop that limits the inflammatory response. Hao Zhou, Minjia Yu, Koichi Fukuda, Jinteak Im, Peng Yao, Wei Cui, Katarzyna Bulek, Jarod Zepp, Youzhong Wan, Tae Whan Kim, Weiguo Yin, Victoria Ma, James Thomas, Jun Gu, Jian-an Wang, Paul E DiCorleto, Paul L Fox, Jun Qin and Xiaoxia Li The EMBO Journal (2013), 32, 583 - 596; 10.1038/emboj.2013.2 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 01 February 2013 Subject Categories: Signal Transduction | Immunology Kif3a interacts with Dynactin subunit p150Glued to organize centriole subdistal appendages In addition to its roles in intraflagellar transport as a subunit of kinesin-II, Kif3a has a motor-independent role in centrioles where it is required for centriole cohesion, subdistal appendage formation and microtubule anchoring Andrew Kodani, Maria Salomé Sirerol-Piquer, Allen Seol, Jose Manuel Garcia-Verdugo and Jeremy F Reiter The EMBO Journal (2013), 32, 597 - 607; 10.1038/emboj.2013.3 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 05 February 2013 Subject Categories: Cell and Tissue Architecture Advertisement EMBO - Transparency in Scientific Publishing The EMBO Journal has a fair and transparent process to rapidly publish your best science. 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