Nature Reviews Microbiology contents March 2013 Volume 11 Number 3 pp 143-217

TABLE OF CONTENTS
March 2013 Volume 11 Number 3
Impact Factor 21.182 *	In this issue Editorial Research Highlights News and Analysis Progress Reviews Analysis Perspectives Also this month Article Series: Vector-borne diseases  Featured article: The microbiome explored: recent insights and future challenges Martin Blaser, Peer Bork, Claire Fraser, Rob Knight & Jun Wang
Subscribe   Facebook   RSS   Recommend to library   Twitter
Advertisement
Nature Reviews Immunology Focus on The inbetweeners: innate-like lymphocytes This Focus issue features Review and Perspective articles on the 'inbetweeners' of the immune system, and a Guidelines article proposing a uniform nomenclature for the emerging innate lymphoid cell subsets. Read the Focus online at: www.nature.com/nri/focus/innate-likelymphocytes
EDITORIAL		Top
Looking inwards p143 | doi:10.1038/nrmicro2987 The publication of a new article type prompts us to have a look back at the evolution and development of the journal over the past decade. Abstract | Full Text | PDF
RESEARCH HIGHLIGHTS Top Cellular microbiology: Mycobacterium leprae turns back the clock p145 | doi:10.1038/nrmicro2975 Mycobacterium leprae triggers reprogramming of Schwann cells to promote its dissemination. PDF Environmental microbiology: Plant bacteria thrive in storm clouds p146 | doi:10.1038/nrmicro2978 The first comprehensive biogeochemical survey of a storm cloud reveals a selection bias for plant-associated bacteria over soil bacteria, which could influence the global distribution of bacteria. PDF IN THE NEWS Entering a post-antibiotic era? p146 | doi:10.1038/nrmicro2983 PDF Bacterial pathogenesis: sRNA clears the way for G4 p146 | doi:10.1038/nrmicro2985 Transcription of an sRNA is required for formation of a G4 structure that allows pilin antigenic variation in Neisseria gonorrhoeae. PDF Virus genetics: Schmallenberg virus reveals its secrets p147 | doi:10.1038/nrmicro2986 Two groups report the development of a reverse genetics system to recover Schmallenberg virus from cloned cDNA. PDF Bacterial physiology: No rest for the persisters p148 | doi:10.1038/nrmicro2969 On exposure to a cell wall synthesis inhibitor, Mycobacterium smegmatis persisters enter a dynamic state of balanced cell division and death. PDF Biofilms: Survival of the wrinkliest p148 | doi:10.1038/nrmicro2972 The formation of wrinkles in Pseudomonas aeruginosa biofilms is a redox-driven adaptation to maximize oxygen accessibility, indicating that redox homeostasis is an important determinant of biofilm morphogenesis. PDF Fungal Pathogenesis: The advantages of keeping your offspring quiet p148 | doi:10.1038/nrmicro2976 Phytophthora sojae evades host immunity by silencing avirulence genes over multiple generations. PDF IN BRIEF Parasite biology: Shedding light on Toxoplasma invasion | Marine microbiology: A day in the life of a microplankton community | Antimicrobials: Aminoglycosides flip the switch on resistance PDF Microbiology JOBS of the week Senior Research Technologist Cleveland Clinic Foundation Assistant / Associate Professor of Immunology and Infectious Diseases Harvard School of Public Health Postdoctoral Position University of Alberta - Department of Biological Sciences Postdoc Fellow in RNA Biology and Genomics University of California - Los Angeles More Science jobs from Microbiology EVENT Society for General Microbiology Spring Conference 2013 03.5.13 Manchester, UK More science events from
NEWS AND ANALYSIS		Top
GENOME WATCH Sherlock Genomes — viral investigator Sarah E. Smith & Rachael S. Wash p150 | doi:10.1038/nrmicro2979 This month's Genome Watch highlights how deep sequencing technologies have vastly reduced the time and prior knowledge needed to generate viral genomes. PDF
PROGRESS		Top
Extreme sweetness: protein glycosylation in archaea Jerry Eichler p151 | doi:10.1038/nrmicro2957 N-glycosylation was first reported in archaea almost 40 years ago. However, as Jerry Eichler describes in this Progress article, it is only recently, with the ready availability of archaeal genome sequences and new and improved molecular tools, that we have begun to make major advances in our understanding of this crucial post-translational modification. Abstract | Full Text | PDF
REVIEWS		Top
Sticking together: building a biofilm the Bacillus subtilis way Hera Vlamakis, Yunrong Chai, Pascale Beauregard, Richard Losick & Roberto Kolter p157 | doi:10.1038/nrmicro2960 Bacillus subtilis has emerged as an important model organism for the study of biofilms. In this Review, Kolter, Losick and colleagues discuss the regulation of B. subtilis biofilm assembly and highlight two emerging areas in the field: biofilm formation on natural substrates and biofilm disassembly. Abstract | Full Text | PDF | Supplementary information
RNA viruses and the host microRNA machinery Benjamin R. tenOever p169 | doi:10.1038/nrmicro2971 Small RNAs (sRNAs) are used by plants, nematodes and arthropods in cellular defence against viruses, but in chordates, sRNAs were replaced with a protein-based system to inhibit viral replication. Here, Benjamin tenOever describes how the lack of interplay between cellular sRNAs and RNA viruses permits the engineering of vectors that can deliver their own sRNAs or are controlled by the sRNAs present in the host. Abstract | Full Text | PDF
Article series: Vector-borne diseases Beyond insecticides: new thinking on an ancient problem Elizabeth A. McGraw & Scott L. O'Neill p181 | doi:10.1038/nrmicro2968 In addition to developing vaccines and drugs that target vector-borne diseases, historically the use of insecticides has been the main approach for targeting the vector itself. However, as McGraw and O'Neill describe in this Review, there has been substantial recent progress in developing alternative genetic and biological vector-control strategies. Abstract | Full Text | PDF
Popping the cork: mechanisms of phage genome ejection Ian J. Molineux & Debabrata Panja p194 | doi:10.1038/nrmicro2988 Despite 60 years of investigation, our understanding of the mechanisms by which phages eject their genomes into target bacterial cells remains incomplete. Here, Molineux and Panja describe the structure of DNA inside the phage head and discuss the current models for DNA ejection both in vitro and in vivo. Abstract | Full Text | PDF
ANALYSIS		Top
Shallow breathing: bacterial life at low O2 Rachel L. Morris & Thomas M. Schmidt p205 | doi:10.1038/nrmicro2970 In this Analysis article, Morris and Schmidt report the results of surveys searching for high-affinity terminal oxidase genes in sequenced bacterial genomes and shotgun metagenomes. They find that bacteria with the potential to respire under microoxic conditions are phylogenetically diverse and intriguingly widespread in nature, and go on to highlight the importance of microaerobic metabolism in host-associated bacteria. Abstract | Full Text | PDF | Supplementary information
PERSPECTIVES		Top
VIEWPOINT The microbiome explored: recent insights and future challenges Martin Blaser, Peer Bork, Claire Fraser, Rob Knight & Jun Wang p213 | doi:10.1038/nrmicro2973 Here, Blaser, Bork, Fraser, Knight and Wang highlight the most exciting findings in the field of microbiome research and discuss what will be necessary to obtain a better understanding of the role of the microbiota in human health and disease, and to develop microbiota-based therapies. Abstract | Full Text | PDF
Advertisement
SUBSCRIBE to Nature Reviews Microbiology TODAY and receive your own personal copy delivered directly to your door each month. PLUS you will gain full online access to the entire archive since launch. Nature Reviews Microbiology is the no. 1 monthly review journal in microbiology*. Ensure you have access.
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com More Nature Events

*2011 Journal Citation Report (Thomson Reuters, 2012)

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department For print subscription enquiries, please contact our subscription department For other enquiries, please contact our feedback department Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2013 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.