Journal of Investigative Dermatology - Table of Contents alert Volume 133 Issue 3

TABLE OF CONTENTS Volume 133, Issue 3 (March 2013) In this issue Editorial Research Techniques Made Simple Commentaries Perspective Original Articles Letters to the Editor Corrigenda Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement Ionizing Radiation: The Good, the Bad, and the Ugly In our latest skinpod Dr. Robert Dellavalle speaks with Dr. Julie Ryan about ionizing radiation. Although a common treatment for cancer, ionizing radiation can potentially damage skin. There is currently no effective method to prevent skin injury due to radiation exposure.   Editorial Top The Ever-Evolving Landscape for Detection of Early Melanoma: Challenges and Promises Alan C Geller and Allan C Halpern J Invest Dermatol 2013 133: 583-585; 10.1038/jid.2012.360 Abstract | Full Text | PDF Clinical Snippets J Invest Dermatol 2013 133: 586; 10.1038/jid.2012.513 Abstract | Full Text | PDF BJD Editor's Choice J Invest Dermatol 2013 133: 587; 10.1038/jid.2012.514 Abstract | Full Text | PDF Editors' Picks J Invest Dermatol 2013 133: 588; 10.1038/jid.2012.515 Abstract | Full Text | PDF Research Techniques Made Simple Top Polymerase Chain Reaction Lilit Garibyan and Nidhi Avashia J Invest Dermatol 2013 133: e6; 10.1038/jid.2013.1 Abstract | Full Text | PDF Commentaries Top Vitamin D Level and Basal Cell Carcinoma, Squamous Cell Carcinoma, and Melanoma Risk Kavitha K Reddy J Invest Dermatol 2013 133: 589-592; 10.1038/jid.2012.427 Abstract | Full Text | PDF COUP-TF-Interacting Protein-2 (Ctip2): Driving the Coupé of Sphingolipid Biosynthesis in the Epidermis Wendy B Bollag J Invest Dermatol 2013 133: 593-594; 10.1038/jid.2012.423 Abstract | Full Text | PDF Combination Therapy of Immunocytokines with Ipilimumab: A Cure for Melanoma? Tao Wang, Rajasekharan Somasundaram and Meenhard Herlyn J Invest Dermatol 2013 133: 595-596; 10.1038/jid.2012.433 Abstract | Full Text | PDF Nevus Sebaceus Is a Mosaic RASopathy Rudolf Happle J Invest Dermatol 2013 133: 597-600; 10.1038/jid.2012.447 Abstract | Full Text | PDF Perspective Top γ-Secretase Mutations in Hidradenitis Suppurativa: New Insights into Disease Pathogenesis Andrew E Pink, Michael A Simpson, Nemesha Desai, Richard C Trembath and Jonathan N W Barker J Invest Dermatol 2013 133: 601-607; advance online publication, October 25, 2012; 10.1038/jid.2012.372 Abstract | Full Text | PDF Original Articles Top CELL BIOLOGY Serum Response Factor Controls Transcriptional Network Regulating Epidermal Function and Hair Follicle Morphogenesis Congxing Lin, Anna Hindes, Carole J Burns, Aaron C Koppel, Alexi Kiss, Yan Yin, Liang Ma, Miroslav Blumenberg, Denis Khnykin, Frode L Jahnsen, Seth D Crosby, Narendrakumar Ramanan and Tatiana Efimova J Invest Dermatol 2013 133: 608-617; advance online publication, November 15, 2012; 10.1038/jid.2012.378 Abstract | Full Text | PDF CELL BIOLOGY Differentiation of Human Embryonic Stem Cells into Clinically Amenable Keratinocytes in an Autogenic Environment Fahad K Kidwai, Hua Liu, Wei Seong Toh, Xin Fu, Doorgesh S Jokhun, Mohammad M Movahednia, Mingming Li, Yu Zou, Christopher A Squier, Toan T Phan and Tong Cao J Invest Dermatol 2013 133: 618-628; advance online publication, December 13, 2012; 10.1038/jid.2012.384 Abstract | Full Text | PDF CLINICAL RESEARCH Plasma 25-Hydroxyvitamin D and Risk of Non-Melanoma and Melanoma Skin Cancer: A Prospective Cohort Study Shoaib Afzal, Børge G Nordestgaard and Stig E Bojesen J Invest Dermatol 2013 133: 629-636; advance online publication, November 29, 2012; 10.1038/jid.2012.395 Abstract | Full Text | PDF CLINICAL RESEARCH Vitamin D Status and Skin Cancer Risk Independent of Time Outdoors: 11-Year Prospective Study in an Australian Community Jolieke C van der Pols, Anne Russell, Ulrike Bauer, Rachel E Neale, Michael G Kimlin and Adèle C Green J Invest Dermatol 2013 133: 637-641; advance online publication, October 18, 2012; 10.1038/jid.2012.346 Abstract | Full Text | PDF CLINICAL RESEARCH Systemic Immune Suppression Predicts Diminished Merkel Cell Carcinoma–Specific Survival Independent of Stage Kelly G Paulson, Jayasri G Iyer, Astrid Blom, E Margaret Warton, Monica Sokil, Lola Yelistratova, Louise Schuman, Kotaro Nagase, Shailender Bhatia, Maryam M Asgari and Paul Nghiem J Invest Dermatol 2013 133: 642-646; advance online publication, November 29, 2012; 10.1038/jid.2012.388 Abstract | Full Text | PDF CONNECTIVE TISSUE Increased KGF Expression Promotes Fibroblast Activation in a Double Paracrine Manner Resulting in Cutaneous Fibrosis Johanna Canady, Stephanie Arndt, Sigrid Karrer and Anja K Bosserhoff J Invest Dermatol 2013 133: 647-657; advance online publication, October 25, 2012; 10.1038/jid.2012.389 Abstract | Full Text | PDF CONNECTIVE TISSUE Enhancing Structural Support of the Dermal Microenvironment Activates Fibroblasts, Endothelial Cells, and Keratinocytes in Aged Human Skin In Vivo Taihao Quan, Frank Wang, Yuan Shao, Laure Rittié, Wei Xia, Jeffrey S Orringer, John J Voorhees and Gary J Fisher J Invest Dermatol 2013 133: 658-667; advance online publication, October 25, 2012; 10.1038/jid.2012.364 Abstract | Full Text | PDF GENETICS Transcription Factor Ctip2 Controls Epidermal Lipid Metabolism and Regulates Expression of Genes Involved in Sphingolipid Biosynthesis during Skin Development Zhixing Wang, Jay S Kirkwood, Alan W Taylor, Jan F Stevens, Mark Leid, Gitali Ganguli-Indra and Arup K Indra J Invest Dermatol 2013 133: 668-676; advance online publication, October 25, 2012; 10.1038/jid.2012.358 Abstract | Full Text | PDF GENETICS Copy Number Variation Analysis in 98 Individuals with PHACE Syndrome Dawn H Siegel, Joseph T C Shieh, Eun-kyung Kwon, Eulalia Baselga, Francine Blei, Maria Cordisco, William B Dobyns, Kelly J Duffy, Maria C Garzon, David L Gibbs, Johannes F Grimmer, Susan J Hayflick, Alfons L Krol, Pui-Yan Kwok, Rachel Lorier, Andrea Matter, Shannon McWeeney, Denise Metry, Sheri Mitchell, Elena Pope, Jennifer L Santoro, David A Stevenson, Pinar Bayrak-Toydemir, Beth Wilmot, Elizabeth A Worthey, Ilona J Frieden, Beth A Drolet and Ulrich Broeckel J Invest Dermatol 2013 133: 677-684; advance online publication, October 25, 2012; 10.1038/jid.2012.367 Abstract | Full Text | PDF GENETICS Local Delivery of Gene-Modifying Triplex-Forming Molecules to the Epidermis Faye A Rogers, Rong-Hua Hu and Leonard M Milstone J Invest Dermatol 2013 133: 685-691; advance online publication, September 27, 2012; 10.1038/jid.2012.351 Abstract | Full Text | PDF IMMUNOLOGY/INFECTION Gene Profiling of Narrowband UVB–Induced Skin Injury Defines Cellular and Molecular Innate Immune Responses Milène Kennedy Crispin, Judilyn Fuentes-Duculan, Nicholas Gulati, Leanne M Johnson-Huang, Tim Lentini, Mary Sullivan-Whalen, Patricia Gilleaudeau, Inna Cueto, Mayte Suárez-Fariñas, Michelle A Lowes and James G Krueger J Invest Dermatol 2013 133: 692-701; advance online publication, November 15, 2012; 10.1038/jid.2012.359 Abstract | Full Text | PDF IMMUNOLOGY/INFECTION Therapeutic Potential of B and T Lymphocyte Attenuator Expressed on CD8+ T Cells for Contact Hypersensitivity Daiki Nakagomi, Kotaro Suzuki, Junichi Hosokawa, Yoshihisa Kobayashi, Akira Suto, Hiroaki Takatori, Norihiko Watanabe, Hiroyuki Matsue, Theresa L Murphy, Kenneth M Murphy, Shinji Shimada and Hiroshi Nakajima J Invest Dermatol 2013 133: 702-711; advance online publication, November 29, 2012; 10.1038/jid.2012.396 Abstract | Full Text | PDF IMMUNOLOGY/INFECTION Alteration of the EphA2/Ephrin-A Signaling Axis in Psoriatic Epidermis Kristin Gordon, James J Kochkodan, Hanz Blatt, Samantha Y Lin, Nihal Kaplan, Andrew Johnston, William R Swindell, Paul Hoover, Bethanee J Schlosser, James T Elder, Johann E Gudjonsson and Spiro Getsios J Invest Dermatol 2013 133: 712-722; advance online publication, November 29, 2012; 10.1038/jid.2012.391 Abstract | Full Text | PDF IMMUNOLOGY/INFECTION Glutamine Suppresses DNFB-Induced Contact Dermatitis by Deactivating p38 Mitogen–Activated Protein Kinase via Induction of MAPK Phosphatase-1 Otgonzaya Ayush, Chang-Hoon Lee, Hae-Kyoung Kim, Suhn-Young Im, Baik-Hwan Cho and Hern-Ku Lee J Invest Dermatol 2013 133: 723-731; advance online publication, October 18, 2012; 10.1038/jid.2012.373 Abstract | Full Text | PDF IMMUNOLOGY/INFECTION Loss of Extracellular Superoxide Dismutase Induces Severe IL-23-Mediated Skin Inflammation in Mice Yun Sang Lee, In-Su Cheon, Byung-Hak Kim, Myung-Ja Kwon, Han-Woong Lee and Tae-Yoon Kim J Invest Dermatol 2013 133: 732-741; advance online publication, December 6, 2012; 10.1038/jid.2012.406 Abstract | Full Text | PDF KERATINOCYTES/EPIDERMIS Caspase-14-Deficient Mice Are More Prone to the Development of Parakeratosis Esther Hoste, Geertrui Denecker, Barbara Gilbert, Filip Van Nieuwerburgh, Leslie van der Fits, Bob Asselbergh, Riet De Rycke, Jean-Pierre Hachem, Dieter Deforce, Errol P Prens, Peter Vandenabeele and Wim Declercq J Invest Dermatol 2013 133: 742-750; advance online publication, September 27, 2012; 10.1038/jid.2012.350 Abstract | Full Text | PDF MELANOCYTES/MELANOMA The Immunocytokine L19–IL2 Eradicates Cancer When Used in Combination with CTLA-4 Blockade or with L19-TNF Kathrin Schwager, Teresa Hemmerle, David Aebischer and Dario Neri J Invest Dermatol 2013 133: 751-758; advance online publication, October 25, 2012; 10.1038/jid.2012.376 Abstract | Full Text | PDF MELANOCYTES/MELANOMA MAGE-C2 Promotes Growth and Tumorigenicity of Melanoma Cells, Phosphorylation of KAP1, and DNA Damage Repair Neehar Bhatia, Tony Z Xiao, Kimberly A Rosenthal, Imtiaz A Siddiqui, Saravanan Thiyagarajan, Brendan Smart, Qiao Meng, Cindy L Zuleger, Hasan Mukhtar, Shannon C Kenney, Mark R Albertini and B Jack Longley J Invest Dermatol 2013 133: 759-767; advance online publication, October 25, 2012; 10.1038/jid.2012.355 Abstract | Full Text | PDF MELANOCYTES/MELANOMA miR-137 Inhibits the Invasion of Melanoma Cells through Downregulation of Multiple Oncogenic Target Genes Chonglin Luo, Paul W Tetteh, Patrick R Merz, Elke Dickes, Alia Abukiwan, Agnes Hotz-Wagenblatt, Stefan Holland-Cunz, Tobias Sinnberg, Birgit Schittek, Dirk Schadendorf, Sven Diederichs and Stefan B Eichmüller J Invest Dermatol 2013 133: 768-775; advance online publication, November 15, 2012; 10.1038/jid.2012.357 Abstract | Full Text | PDF PHOTOBIOLOGY Opening of Chloride Channels by 1α,25-Dihydroxyvitamin D3 Contributes to Photoprotection against UVR-Induced Thymine Dimers in Keratinocytes Vanessa B Sequeira, Mark S Rybchyn, Clare Gordon-Thomson, Wannit Tongkao-on, Mathew T Mizwicki, Anthony W Norman, Vivienne E Reeve, Gary M Halliday and Rebecca S Mason J Invest Dermatol 2013 133: 776-782; advance online publication, September 27, 2012; 10.1038/jid.2012.343 Abstract | Full Text | PDF WOUND HEALING Reduced Il17a Expression Distinguishes a Ly6cloMHCIIhi Macrophage Population Promoting Wound Healing Mathieu P Rodero, Samantha S Hodgson, Brett Hollier, Christophe Combadiere and Kiarash Khosrotehrani J Invest Dermatol 2013 133: 783-792; advance online publication, December 13, 2012; 10.1038/jid.2012.368 Abstract | Full Text | PDF WOUND HEALING Lysophosphatidic Acid Promotes Cell Migration through STIM1- and Orai1-Mediated Ca2+i Mobilization and NFAT2 ActivationJIDOpen Ralph Jans, Laura Mottram, Darren L Johnson, Anna M Brown, Stephen Sikkink, Kehinde Ross and Nick J Reynolds J Invest Dermatol 2013 133: 793-802; advance online publication, October 25, 2012; 10.1038/jid.2012.370 Abstract | Full Text | PDF WOUND HEALING Treatment of Dermal Fibroblasts with GPI-Anchored Human TIMP-1 Protein Moderates Processes Linked to Scar Formation Roghieh Djafarzadeh, Susan Notohamiprodjo, Nicole Rieth, Monika Hofstetter, Elfriede Noessner and Peter J Nelson J Invest Dermatol 2013 133: 803-811; advance online publication, October 25, 2012; 10.1038/jid.2012.375 Abstract | Full Text | PDF WOUND HEALING An In Vivo Screen of Secreted Proteins Identifies Adiponectin as a Regulator of Murine Cutaneous Wound HealingJIDOpen Neeraj S Salathia, Jian Shi, Jay Zhang and Richard J Glynne J Invest Dermatol 2013 133: 812-821; advance online publication, October 25, 2012; 10.1038/jid.2012.374 Abstract | Full Text | PDF Letters to the Editor Top Hair Steroid Profiling Reveals Racial Differences in Male Pattern Baldness between Korean and Caucasian Populations Man Ho Choi, Sun Ju Kim, Bark-Lynn Lew, Woo Young Sim and Bong Chul Chung J Invest Dermatol 2013 133: 822-824; advance online publication, November 15, 2012; 10.1038/jid.2012.349 Abstract | Full Text | PDF Mosaic Activating RAS Mutations in Nevus Sebaceus and Nevus Sebaceus Syndrome Bryan K Sun, Andrea Saggini, Kavita Y Sarin, Jinah Kim, Latanya Benjamin, Philip E LeBoit and Paul A Khavari J Invest Dermatol 2013 133: 824-827; advance online publication, October 25, 2012; 10.1038/jid.2012.377 Abstract | Full Text | PDF Whole-Exome Sequencing Reveals Somatic Mutations in HRAS and KRAS, which Cause Nevus Sebaceus Jonathan L Levinsohn, Li C Tian, Lynn M Boyden, Jennifer M McNiff, Deepak Narayan, Erin S Loring, Duri Yun, Jeffrey L Sugarman, John D Overton, Shrikant M Mane, Richard P Lifton, Amy S Paller, Annette M Wagner, Richard J Antaya and Keith A Choate J Invest Dermatol 2013 133: 827-830; advance online publication, October 25, 2012; 10.1038/jid.2012.379 Abstract | Full Text | PDF Genetic Profiling of BRAF Inhibitor–Induced Keratoacanthomas Reveals No Induction of MAP Kinase Pathway Expression Rajan P Kulkarni, Seema Plaisier, Seong H Ra, Xinmin Li, Delphine J Lee, Joseph D Hillman and Scott W Binder J Invest Dermatol 2013 133: 830-833; advance online publication, September 27, 2012; 10.1038/jid.2012.353 Abstract | Full Text | PDF A Single-Nucleotide Polymorphism in the Abcc6 Gene Associates with Connective Tissue Mineralization in Mice Similar to Targeted Models for Pseudoxanthoma Elasticum Annerose Berndt, Qiaoli Li, Christopher S Potter, Yanhua Liang, Kathleen A Silva, Victoria Kennedy, Jouni Uitto and John P Sundberg J Invest Dermatol 2013 133: 833-836; advance online publication, September 27, 2012; 10.1038/jid.2012.340 Abstract | Full Text | PDF Association of Cardiovascular and Metabolic Disease Genes with Psoriasis Yingchang Lu, Haoyan Chen, Pernilla Nikamo, Hui Qi Low, Cynthia Helms, Mark Seielstad, Jianjun Liu, Anne M Bowcock, Mona Stahle and Wilson Liao J Invest Dermatol 2013 133: 836-839; advance online publication, November 29, 2012; 10.1038/jid.2012.366 Abstract | Full Text | PDF A c-kit Mutation in Exon 18 in Familial Mastocytosis Stefan Wöhrl, Katharina B Moritz, Andreas Bracher, Gottfried Fischer, Georg Stingl and Robert Loewe J Invest Dermatol 2013 133: 839-841; advance online publication, November 29, 2012; 10.1038/jid.2012.394 Abstract | Full Text | PDF A Method for Intravital Monitoring of Human Cells Using a Far-Red Luminescent Probe in Graft-Versus-Host Disease Model Mice Hongjiang Qiao, Riichiro Abe, Nao Saito, Yasuyuki Fujita, Inkin Hayashi-Ujiie, Gang Wang, Sanae Haga, Chun Wu, Yoshihiro Ohmiya, Michitaka Ozaki and Hiroshi Shimizu J Invest Dermatol 2013 133: 841-843; advance online publication, September 27, 2012; 10.1038/jid.2012.345 Abstract | Full Text | PDF Autoimmune Disease Induction in a Healthy Human Organ: A Humanized Mouse Model of Alopecia Areata Amos Gilhar, Aviad Keren, Avner Shemer, Roberto d'Ovidio, Yehuda Ullmann and Ralf Paus J Invest Dermatol 2013 133: 844-847; advance online publication, October 25, 2012; 10.1038/jid.2012.365 Abstract | Full Text | PDF High Anti-Staphylococcal Antibody Titers in Patients with Epidermolysis Bullosa Relate to Long-Term Colonization with Alternating Types of Staphylococcus aureus Magdalena M van der Kooi-Pol, Corné P de Vogel, Gerlinde N Westerhout-Pluister, Yanka K Veenstra-Kyuchukova, José C Duipmans, Corinna Glasner, Girbe Buist, Goffe S Elsinga, Hans Westra, Hendrik P J Bonarius, Herman Groen, Willem J B van Wamel, Hajo Grundmann, Marcel F Jonkman and Jan Maarten van Dijl J Invest Dermatol 2013 133: 847-850; advance online publication, September 27, 2012; 10.1038/jid.2012.347 Abstract | Full Text | PDF Keratin Intracellular Concentration Revisited: Implications for Keratin Function in Surface Epithelia Xia Feng, Hao Zhang, Joseph B Margolick and Pierre A Coulombe J Invest Dermatol 2013 133: 850-853; advance online publication, November 29, 2012; 10.1038/jid.2012.397 Abstract | Full Text | PDF No Evidence for Viral Sequences in Mycosis Fungoides and Sézary Syndrome Skin Lesions: A High-Throughput Sequencing Approach Olivier Dereure, Justine Cheval, Aurélie Du Thanh, Kevin Pariente, Virginie Sauvage, Jean Claude Manuguerra, Valérie Caro, Vincent Foulongne and Marc Eloit J Invest Dermatol 2013 133: 853-855; advance online publication, October 25, 2012; 10.1038/jid.2012.371 Abstract | Full Text | PDF Parakeratotic Corneocytes Play a Unique Role in Human Skin Wound Healing Marcia L Usui, Robert A Underwood, Philip Fleckman and John E Olerud J Invest Dermatol 2013 133: 856-858; advance online publication, September 27, 2012; 10.1038/jid.2012.352 Abstract | Full Text | PDF Corrigenda Top Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1 Ji Li, Ting-Xin Jiang, Michael W Hughes, Ping Wu, Juehua Yu, Randall B Widelitz, Guoping Fan and Cheng-Ming Chuong J Invest Dermatol 2013 133: 859; advance online publication, September 20, 2012; 10.1038/jid.2012.348 Abstract | Full Text | PDF Interferon Regulatory Factor 6 Promotes Differentiation of the Periderm by Activating Expression of Grainyhead-Like 3 Gabriel de la Garza, Jack Robert Schleiffarth, Martine Dunnwald, Anuj Mankad, Jason L Weirather, Gregory Bonde, Stephen Butcher, Tamer A Mansour, Youssef A Kousa, Cindy F Fukazawa, Douglas W Houston, J Robert Manak, Brian C Schutte, Daniel S Wagner and Robert A Cornell J Invest Dermatol 2013 133: 859; advance online publication, November 29, 2012; 10.1038/jid.2012.380 Abstract | Full Text | PDF Marrow-Derived Stromal Cell Delivery on Fibrin Microbeads Can Correct Radiation-Induced Wound-Healing Deficits Michael W Xie, Raphael Gorodetsky, Ewa D Micewicz, Natalia C Mackenzie, Elena Gaberman, Lilia Levdansky and William H McBride J Invest Dermatol 2013 133: 859; advance online publication, November 29, 2012; 10.1038/jid.2012.381 Abstract | Full Text | PDF Advertisement Follow JID on Facebook for access to news, comments and articles. 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