Thursday, November 8, 2012

Scientific Reports Biology Table of Contents e-alert: November 2012

  08 November 2012   
 
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Biological Sciences
 
 
 
 
 
 
 

Non-randomized mtDNA damage after ionizing radiation via charge transport

 
 

Xin Zhou, Xinguo Liu, Xin Zhang et al.

 
 

Although it is well known that there are mutation hot spots in mtDNA, whether there are damage hot spots remain elusive. In this study, the regional DNA damage of mitochondrial …

 
 
 
 
 
 

Multiple mutations and mutation combinations in the sodium channel of permethrin resistant mosquitoes, Culex quinquefasciatus

 
 

Ting Li, Lee Zhang, William R. Reid et al.

 
 

A previous study identified 3 nonsynonymous and 6 synonymous mutations in the entire mosquito sodium channel of Culex quinquefasciatus, the prevalence of which were strongly …

 
 
 
 
 
 

Neutron diffraction studies of the interaction between amphotericin B and lipid-sterol model membranes

 
 

Fabrizia Foglia, M. Jayne Lawrence, Bruno Demė et al.

 
 

Over the last 50 years or so, amphotericin has been widely employed in treating life-threatening systemic fungal infections. Its usefulness in the clinic, however, has always been …

 
 
 
 
 
 

Sequential origin in the high performance properties of orb spider dragline silk

 
 

Todd A. Blackledge, José Pérez-Rigueiro, Gustavo R. Plaza et al.

 
 

Major ampullate (MA) dragline silk supports spider orb webs, combining strength and extensibility in the toughest biomaterial. MA silk evolved ~376 MYA and identifying how …

 
 
 
 
 
 

Use of Direct Gradient Analysis to Uncover Biological Hypotheses in 16S Survey Data and Beyond

 
 

John R. Erb-Downward, Amir A. Sadighi Akha, Juan Wang et al.

 
 

This study investigated the use of direct gradient analysis of bacterial 16S pyrosequencing surveys to identify relevant bacterial community signals in the midst of a "noisy" …

 
 
 
 
 
 

Counterflow Dielectrophoresis for Trypanosome Enrichment and Detection in Blood

 
 

Anoop Menachery, Clemens Kremer, Pui E. Wong et al.

 
 

Human African trypanosomiasis or sleeping sickness is a deadly disease endemic in sub-Saharan Africa, caused by single-celled protozoan parasites. Although it has been targeted …

 
 
 
 
 
 

When not to copy: female fruit flies use sophisticated public information to avoid mated males

 
 

Adeline Loyau, Simon Blanchet, Pauline Van Laere et al.

 
 

Semen limitation (lack of semen to fertilize all of a female's eggs) imposes high fitness costs to female partners. Females should therefore avoid mating with semen-limited males. …

 
 
 
 
 
 

Positive and negative selection, self-nonself discrimination and the roles of costimulation and anergy

 
 

P. Mostardinha, F. Vistulo de Abreu

 
 

It is still unclear whether the adaptive immune system can perform accurate self-nonself discrimination and what could influence its performance. Starting from simple cellular …

 
 
 
 
 
 

Estimating the proportion of variation in susceptibility to multiple sclerosis captured by common SNPs

 
 

Corey T. Watson, Giulio Disanto, Felix Breden et al.

 
 

Multiple sclerosis (MS) is a complex disease with underlying genetic and environmental factors. Although the contribution of alleles within the major histocompatibility complex …

 
 
 
 
 
 

12-Chemokine Gene Signature Identifies Lymph Node-like Structures in Melanoma: Potential for Patient Selection for Immunotherapy?

 
 

Jane L. Messina, David A. Fenstermacher, Steven Eschrich et al.

 
 

We have interrogated a 12-chemokine gene expression signature (GES) on genomic arrays of 14,492 distinct solid tumors and show broad distribution across different histologies. We …

 
 
 
 
 
 

Differential expression of HIV-1 interfering factors in monocyte-derived macrophages stimulated with polarizing cytokines or interferons

 
 

Viviana Cobos Jiménez, Thijs Booiman, Steven W. de Taeye et al.

 
 

HIV-1 replication in macrophages can be regulated by cytokines and infection is restricted in macrophages activated by type I interferons and polarizing cytokines. Here, we …

 
 
 
 
 
 

Conserved and divergent elements in Torso RTK activation in Drosophila development

 
 

Marco Grillo, Marc Furriols, Cristina de Miguel et al.

 
 

The repeated use of signalling pathways is a common phenomenon but little is known about how they become co-opted in different contexts. Here we examined this issue by analysing …

 
 
 
 
 
 

Microbial diversity in long-term water-flooded oil reservoirs with different in situ temperatures in China

 
 

Fan Zhang, Yue-Hui She, Lu-Jun Chai et al.

 
 

Water-flooded oil reservoirs have specific ecological environments due to continual water injection and oil production and water recycling. Using 16S rRNA gene clone library …

 
 
 
 
 
 

Protease-catalysed Direct Asymmetric Mannich Reaction in Organic Solvent

 
 

Yang Xue, Ling-Po Li, Yan-Hong He et al.

 
 

We reported the first enzyme-catalysed, direct, three-component asymmetric Mannich reaction using protease type XIV from Streptomyces griseus (SGP) in acetonitrile. Yields of up …

 
 
 
 
 
 

High-performance method for specific effect on nucleic acids in cells using TiO2~DNA nanocomposites

 
 

Asya S. Levina, Marina N. Repkova, Zinfer R. Ismagilov et al.

 
 

Nanoparticles are used to solve the current drug delivery problem. We present a high-performance method for efficient and selective action on nucleic acid target in cells using …

 
 
 
 
 
 

Evolutionary history of human disease genes reveals phenotypic connections and comorbidity among genetic diseases

 
 

Solip Park, Jae-Seong Yang, Jinho Kim et al.

 
 

The extent to which evolutionary changes have impacted the phenotypic relationships among human diseases remains unclear. In this work, we report that phenotypically similar …

 
 
 
 
 
 

Disturbances in equilibrium function after major earthquake

 
 

Motoyasu Honma, Nobutaka Endo, Yoshihisa Osada et al.

 
 

Major earthquakes were followed by a large number of aftershocks and significant outbreaks of dizziness occurred over a large area. However it is unclear why major earthquake …

 
 
 
 
 
 

ADDENDUM: A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals

 
 

Hisashi Moriguchi, Yue Zhang, Makoto Mihara et al.

 
 

 
 
 
 
 
 

ADDENDUM: Successful cryopreservation of human ovarian cortex tissues using supercooling

 
 

Hisashi Moriguchi, Yue Zhang, Makoto Mihara et al.

 
 

 
 
 
 
 
 

MtDNA analysis of global populations support that major population expansions began before Neolithic Time

 
 

Hong-Xiang Zheng, Shi Yan, Zhen-Dong Qin et al.

 
 

Agriculture resulted in extensive population growths and human activities. However, whether major human expansions started after Neolithic Time still remained controversial. With …

 
 
 
 
 
 

Modelling the effects of sanitary policies on European vulture conservation

 
 

Antoni Margalida, Ma Àngels Colomer

 
 

Biodiversity losses are increasing as a consequence of negative anthropogenic effects on ecosystem dynamics. However, the magnitude and complexity of these effects may still be …

 
 
 
 
 
 

Spontaneous generation of germline characteristics in mouse fibrosarcoma cells

 
 

Zhan Ma, Yao Hu, Guoying Jiang et al.

 
 

Germline/embryonic-specific genes have been found to be activated in somatic tumors. In this study, we further showed that cells functioning as germline could be present in mouse …

 
 
 
 
 
 

Cold Radiofrequency Plasma Treatment Modifies Wettability and Germination Speed of Plant Seeds

 
 

Edward Bormashenko, Roman Grynyov, Yelena Bormashenko et al.

 
 

We report the possibility to modify the wetting properties of the surfaces of a diversity of seeds including: lentils (Lens culinaris), beans (Phaseolus vulgaris) and wheat

 
 
 
 
 
 

Mechanisms of Dendritic Cell Lysosomal Killing of Cryptococcus

 
 

Camaron R. Hole, Hoang Bui, Floyd L. Wormley et al.

 
 

Cryptococcus neoformans is an opportunistic pulmonary fungal pathogen that disseminates to the CNS causing fatal meningitis in immunocompromised patients. Dendritic cells (DCs) …

 
 
 
 
 
 

Beyond pairwise strategy updating in the prisoner's dilemma game

 
 

Xiaofeng Wang, Matjaž Perc, Yongkui Liu et al.

 
 

In spatial games players typically alter their strategy by imitating the most successful or one randomly selected neighbor. Since a single neighbor is taken as reference, the …

 
 
 
 
 
 

The computational influence of neurogenesis in the processing of spatial information in the dentate gyrus

 
 

Javier I. Cuneo, Nicolas H. Quiroz, Victoria I. Weisz et al.

 
 

This study was designed to analyze the effect of hippocampal neurogenesis on the spatial maps of granule cells. Accordingly, we developed and improved an artificial neural network …

 
 
 
 
 
 

Automated and fast building of three-dimensional RNA structures

 
 

Yunjie Zhao, Yangyu Huang, Zhou Gong et al.

 
 

Building tertiary structures of non-coding RNA is required to understand their functions and design new molecules. Current algorithms of RNA tertiary structure prediction give …

 
 
 
 
 
 

Rapid Nipah virus entry into the central nervous system of hamsters via the olfactory route

 
 

Vincent J. Munster, Joseph B. Prescott, Trenton Bushmaker et al.

 
 

Encephalitis is a hallmark of Nipah virus (NiV) infection in humans. The exact route of entry of NiV into the central nervous system (CNS) is unknown. Here, we performed a …

 
 
 
 
 
 

A novel mutation in the Lipase H gene underlies autosomal recessive hypotrichosis and woolly hair

 
 

Muhammad Tariq, Aysha Azhar, Shahid Mahmood Baig et al.

 
 

Mutations in the lipase member H (LIPH) gene cause autosomal recessive hypotrichosis with woolly hair. We report herein on five consanguineous families from Pakistan segregating …

 
 
 
 
 
 

Environmental and genetic controls of soldier caste in a parasitic social wasp

 
 

Kenta Watanabe, Yudai Nishide, Derek A. Roff et al.

 
 

A larval army caste is found in some parasitic wasps with polyembryonic or clonal proliferation, where many clone larvae emerge from a single egg. In contrast to non-parasitic …

 
 
 
 
 
 

Continued Distress among Abandoned Dogs in Fukushima

 
 

Miho Nagasawa, Kazutaka Mogi, Takefumi Kikusui

 
 

In Fukushima, Japan, a prolonged refugee situation caused by a major nuclear incident after the earthquake of March 11, 2011 has led to the unintentional abandonment of many pets. …

 
 
 
 
 
 

Predator-prey role reversals, juvenile experience and adult antipredator behaviour

 
 

Yasuyuki Choh, Maira Ignacio, Maurice W. Sabelis et al.

 
 

Although biologists routinely label animals as predators and prey, the ecological role of individuals is often far from clear. There are many examples of role reversals in …

 
 
 
 
 
 

Zebrafish respond to the geomagnetic field by bimodal and group-dependent orientation

 
 

Akira Takebe, Toshiki Furutani, Tatsunori Wada et al.

 
 

A variety of animals use Earth's magnetic field as a reference for their orientation behaviour. Although distinctive magnetoreception mechanisms have been postulated for many …

 
 
 
 
 
 

Next-generation sequencing coupled with a cell-free display technology for high-throughput production of reliable interactome data

 
 

Shigeo Fujimori, Naoya Hirai, Hiroyuki Ohashi et al.

 
 

Next-generation sequencing (NGS) has been applied to various kinds of omics studies, resulting in many biological and medical discoveries. However, high-throughput protein-protein …

 
 
 
 
 
 

Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides

 
 

Geoffrey Masuyer, Sylva L. U. Schwager, Edward D. Sturrock et al.

 
 

Angiotensin-I converting enzyme (ACE), a two-domain dipeptidylcarboxypeptidase, is a key regulator of blood pressure as a result of its critical role in the …

 
 
 
 
 
 

Abundance, Composition, and Sinking Rates of Fish Fecal Pellets in the Santa Barbara Channel

 
 

Grace K. Saba, Deborah K. Steinberg

 
 

Rapidly sinking fecal pellets are an important component of the vertical flux of particulate organic matter (POM) from the surface to the ocean's interior; however, few studies …

 
 
 
 
 
 

Meal frequency patterns determine the phase of mouse peripheral circadian clocks

 
 

Hiroaki Kuroda, Yu Tahara, Keisuke Saito et al.

 
 

Peripheral circadian clocks in mammals are strongly entrained by light-dark and eating cycles. Their physiological functions are maintained by the synchronization of the phase of …

 
 
 
 
 
 

Attenuation of Streptococcus suis virulence by the alteration of bacterial surface architecture

 
 

Youjun Feng, Min Cao, Jie Shi et al.

 
 

NeuB, a sialic acid synthase catalyzes the last committed step of the de novo biosynthetic pathway of sialic acid, a major element of bacterial surface structure. Here we report a …

 
 
 
 
 
 

ImprimatinC1, a novel plant immune-priming compound, functions as a partial agonist of salicylic acid

 
 

Yoshiteru Noutoshi, Yusuke Jikumaru, Yuji Kamiya et al.

 
 

Plant activators are agrochemicals that protect crops from pathogens. They confer durable resistance to a broad range of diseases by activating intrinsic immune mechanisms in …

 
 
 
 
 
 

Multiplex epitope mapping using bacterial surface display reveals both linear and conformational epitopes

 
 

Elton P. Hudson, Mathias Uhlen, Johan Rockberg

 
 

As antibody-based diagnosis and therapy grow at an increased pace, there is a need for methods which rapidly and accurately determine antibody-antigen interactions. Here, we …

 
 
 
 
 
 

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

 
 

Cristian A. Lasagna-Reeves, Diana L. Castillo-Carranza, Urmi Sengupta et al.

 
 

Intracerebral injection of brain extracts containing amyloid or tau aggregates in transgenic animals can induce cerebral amyloidosis and tau pathology. We extracted pure …

 
 
 
 
 
 
 
 
 
 
 
 

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