Clinical Pharmacology and Therapeutics - Table of Contents alert Volume 92 Issue 6

TABLE OF CONTENTS Volume 92, Issue 6 (December 2012) In this issue In This Issue Editorial News & Views Discovery Perspectives Clinical Trial State of the Art Research Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement New content available each week! Original Research - Reviews & Perspectives - Tutorials CPT: PSP publishes critical content covering the latest advances in quantitative methods as applied in pharmacology, physiology, and therapeutics in humans with a common focus on the application of these two areas on drug development. CPT: PSP is an online open access journal.   In This Issue Top In This Issue Clin Pharmacol Ther 2012 92: 667; 10.1038/clpt.2012.195 Full Text Editorial Top Epigenetics: A New Link Toward Understanding Human Disease and Drug Response A M Cressman and M Piquette-Miller Clin Pharmacol Ther 2012 92: 669-673; 10.1038/clpt.2012.179 Abstract | Full Text News & Views Top HIGHLIGHTS Highlights Clin Pharmacol Ther 2012 92: 674-675; 10.1038/clpt.2012.194 Full Text ASCPT NEWS ASCPT News Clin Pharmacol Ther 2012 92: 676-681; 10.1038/clpt.2012.180 Full Text BOOKS Pharmacogenetics and Individualized Therapy Reviewed by  F Innocenti Clin Pharmacol Ther 2012 92: 682; 10.1038/clpt.2012.185 Full Text Discovery Top Epigenetic Variations in Heredity and Evolution E Jablonka Clin Pharmacol Ther 2012 92: 683-688; advance online publication, October 17, 2012; 10.1038/clpt.2012.158 Full Text Epigenetic Chemical Probes S Müller and P J Brown Clin Pharmacol Ther 2012 92: 689-693; advance online publication, October 24, 2012; 10.1038/clpt.2012.154 Full Text Perspectives Top LETTERS TO THE EDITOR Drug Labels: A Flawed Source of Data for Studying Orphan Drug Approvals A S Kesselheim and J Avorn Clin Pharmacol Ther 2012 92: 694; advance online publication, October 17, 2012; 10.1038/clpt.2012.166 Full Text Response to “Drug Labels: A Flawed Source of Data for Studying Orphan Drug Approvals” M Orfali, C Cassino, J Mardekian and T Cote Clin Pharmacol Ther 2012 92: 694-695; advance online publication, October 10, 2012; 10.1038/clpt.2012.172 Full Text Clinical Trial Top Proarrhythmic Safety of Repeat Doses of Mirabegron in Healthy Subjects: A Randomized, Double-Blind, Placebo-, and Active-Controlled Thorough QT Study M Malik, E M van Gelderen, J H Lee, D L Kowalski, M Yen, R Goldwater, S K Mujais, M P Schaddelee, P de Koning, A Kaibara, S S Moy and J J Keirns Clin Pharmacol Ther 2012 92: 696-706; advance online publication, November 14, 2012; 10.1038/clpt.2012.181 Abstract | Full Text State of the Art Top The Genetic and Epigenetic Basis of Type 2 Diabetes and Obesity A W Drong, C M Lindgren and M I McCarthy Clin Pharmacol Ther 2012 92: 707-715; advance online publication, October 10, 2012; 10.1038/clpt.2012.149 Abstract | Full Text Prenatal and Perinatal Environmental Influences on the Human Fetal and Placental Epigenome K Hogg, E M Price, C W Hanna and W P Robinson Clin Pharmacol Ther 2012 92: 716-726; advance online publication, October 10, 2012; 10.1038/clpt.2012.141 Abstract | Full Text Epigenomics and Interindividual Differences in Drug Response M Ivanov, M Kacevska and M Ingelman-Sundberg Clin Pharmacol Ther 2012 92: 727-736; advance online publication, October 24, 2012; 10.1038/clpt.2012.152 Abstract | Full Text Research Top ARTICLES Measurement and Compartmental Modeling of the Effect of CYP3A5 Gene Variation on Systemic and Intrarenal Tacrolimus Disposition S Zheng, Y Tasnif, M F Hebert, C L Davis, Y Shitara, J C Calamia, Y S Lin, D D Shen and K E Thummel Clin Pharmacol Ther 2012 92: 737-745; advance online publication, October 17, 2012; 10.1038/clpt.2012.175 Abstract | Full Text Impact of the CYP4F2 p.V433M Polymorphism on Coumarin Dose Requirement: Systematic Review and Meta-Analysis E Danese, M Montagnana, J A Johnson, A E Rettie, C F Zambon, S A Lubitz, G Suarez-Kurtz, L H Cavallari, L Zhao, M Huang, Y Nakamura, T Mushiroda, M K Kringen, P Borgiani, C Ciccacci, N T Au, T Langaee, V Siguret, M A Loriot, H Sagreiya, R B Altman, M H A Shahin, S A Scott, S I Khalifa, B Chowbay, I M Suriapranata, M Teichert, B H Stricker, M Taljaard, M R Botton, J E Zhang, M Pirmohamed, X Zhang, J F Carlquist, B D Horne, M T M Lee, V Pengo, G C Guidi, P Minuz and C Fava Clin Pharmacol Ther 2012 92: 746-756; advance online publication, November 7, 2012; 10.1038/clpt.2012.184 Abstract | Full Text HLA Genotype and Carbamazepine-Induced Cutaneous Adverse Drug Reactions: A Systematic Review V L Yip, A G Marson, A L Jorgensen, M Pirmohamed and A Alfirevic Clin Pharmacol Ther 2012 92: 757-765; advance online publication, November 7, 2012; 10.1038/clpt.2012.189 Abstract | Full Text A Population-Based Assessment of the Drug Interaction Between Levothyroxine and Warfarin D Pincus, T Gomes, C Hellings, H Zheng, J M Paterson, M M Mamdani and D N Juurlink Clin Pharmacol Ther 2012 92: 766-770; advance online publication, October 24, 2012; 10.1038/clpt.2012.171 Abstract | Full Text CYP2B6 and Bupropion’s Smoking-Cessation Pharmacology: The Role of Hydroxybupropion A Z X Zhu, L S Cox, N Nollen, B Faseru, K S Okuyemi, J S Ahluwalia, N L Benowitz and R F Tyndale Clin Pharmacol Ther 2012 92: 771-777; advance online publication, November 14, 2012; 10.1038/clpt.2012.186 Abstract | Full Text Advertisement Ensure your access If you are unable to access the articles in thisalert, your library may not subscribe to this journal. 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