Monday, October 1, 2012

Scientific Reports Biology Table of Contents e-alert: October 2012

 01 October 2012  
 
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Biological Sciences
 
 
 
 
 
 
 

Nettle as a distinct Bronze Age textile plant

 
 

C. Bergfjord, U. Mannering, K. M. Frei et al.

 
 

It is generally assumed that the production of plant fibre textiles in ancient Europe, especially woven textiles for clothing, was closely linked to the development of agriculture …

 
 
 
 
 
 

Genomes of surface isolates of Alteromonas macleodii: the life of a widespread marine opportunistic copiotroph

 
 

Mario López-Pérez, Aitor Gonzaga, Ana-Belen Martin-Cuadrado et al.

 
 

Alteromonas macleodii is a marine gammaproteobacterium with widespread distribution in temperate or tropical waters. We describe three genomes of isolates from surface waters …

 
 
 
 
 
 

GTP binding and intramolecular regulation by the ROC domain of Death Associated Protein Kinase 1

 
 

Joseph D. Jebelli, Sybille Dihanich, Laura Civiero et al.

 
 

The ROCO proteins are a family of large, multidomain proteins characterised by the presence of a Ras of complex proteins (ROC) domain followed by a COR, or C-terminal of ROC, …

 
 
 
 
 
 

The hematopoietic cytokine granulocyte-macrophage colony stimulating factor is important for cognitive functions

 
 

Markus Krieger, Martin Both, Simon A. Kranig et al.

 
 

We recently reported expression of hematopoietic growth factor GM-CSF and its receptor (GM-CSFR) in CNS neurons. Here we evaluated this system in learning and memory formation …

 
 
 
 
 
 

Importance of β-Catenin in glucose and energy homeostasis

 
 

Lynda Elghazi, Aaron P. Gould, Aaron J. Weiss et al.

 
 

In settings of increased insulin demand, failure to expand pancreatic β-cells mass leads to diabetes. Genome-wide scans of diabetic populations have uncovered several genes …

 
 
 
 
 
 

Spatial Filter Based Bessel-Like Beam for Improved Penetration Depth Imaging in Fluorescence Microscopy

 
 

Subhajit B. Purnapatra, Sampa Bera, Partha Pratim Mondal

 
 

Monitoring and visualizing specimens at a large penetration depth is a challenge. At depths of hundreds of microns, several physical effects (such as, scattering, PSF distortion …

 
 
 
 
 
 

The efficacy of musical emotions provoked by Mozart's music for the reconciliation of cognitive dissonance

 
 

Nobuo Masataka, Leonid Perlovsky

 
 

Debates on the origin and function of music have a long history. While some scientists argue that music itself plays no adaptive role in human evolution, others suggest that music …

 
 
 
 
 
 

Acquired immunity of transgenic torenia plants overexpressing agmatine coumaroyltransferase to pathogens and herbivore pests

 
 

Atsushi Muroi, Kenji Matsui, Takeshi Shimoda et al.

 
 

We investigated the ability of transgenic torenia (Scrophulariaceae) plants to resist fungi and arthropod herbivores. Torenia hybrida cv. Summerwave Blue was manipulated to …

 
 
 
 
 
 

Release of Cyclic Phosphatidic Acid from Gelatin-based Hydrogels Inhibit Colon Cancer Cell Growth and Migration

 
 

Tamotsu Tsukahara, Kimiko Murakami-Murofushi

 
 

Microparticle and nanoparticle formulations are widely used to improve the bioavailability of low-solubility drugs and as vehicles for organ- and tissue-specific targeted drug …

 
 
 
 
 
 

Primary Role of the Chromophore Bond Length Alternation in Reversible Photoconversion of Red Fluorescence Proteins

 
 

Mikhail Drobizhev, Thomas E. Hughes, Yuriy Stepanenko et al.

 
 

Rapid photobleaching of fluorescent proteins can limit their use in imaging applications. The underlying kinetics is multi-exponential and strongly depends on the local …

 
 
 
 
 
 

Large-scale identification of target proteins of a glycosyltransferase isozyme by Lectin-IGOT-LC/MS, an LC/MS-based glycoproteomic approach

 
 

Daisuke Sugahara, Hiroyuki Kaji, Kazushi Sugihara et al.

 
 

Model organisms containing deletion or mutation in a glycosyltransferase-gene exhibit various physiological abnormalities, suggesting that specific glycan motifs on certain …

 
 
 
 
 
 

PEG-Labeled Nucleotides and Nanopore Detection for Single Molecule DNA Sequencing by Synthesis

 
 

Shiv Kumar, Chuanjuan Tao, Minchen Chien et al.

 
 

We describe a novel single molecule nanopore-based sequencing by synthesis (Nano-SBS) strategy that can accurately distinguish four bases by detecting 4 different sized tags …

 
 
 
 
 
 

COMT Val158Met polymorphism interacts with stressful life events and parental warmth to influence decision making

 
 

Qinghua He, Gui Xue, Chuansheng Chen et al.

 
 

Both genetic and environmental factors have been shown to influence decision making, but their relative contributions and interactions are not well understood. The present study …

 
 
 
 
 
 

Nitric oxide rescues thalidomide mediated teratogenicity

 
 

Jamila H. Siamwala, Vimal Veeriah, M. Krishna Priya et al.

 
 

Thalidomide, a sedative drug given to pregnant women, unfortunately caused limb deformities in thousands of babies. Recently the drug was revived because of its therapeutic …

 
 
 
 
 
 

MHC genotype and near-deterministic mortality in grey seals

 
 

M. de Assunção-Franco, J. I. Hoffman, J. Harwood et al.

 
 

The Major Histocompatability Complex (MHC) is one of the best known and best characterised components of the immune system, yet its functions remain somewhat enigmatic, including …

 
 
 
 
 
 

Is coaching experience associated with effective use of timeouts in basketball?

 
 

Serguei Saavedra, Satyam Mukherjee, James P. Bagrow

 
 

Experience is an important asset in almost any professional activity. In basketball, there is believed to be a positive association between coaching experience and effective use …

 
 
 
 
 
 

Less than 5 Netrin-1 molecules initiate attraction but 200 Sema3A molecules are necessary for repulsion

 
 

Giulietta Pinato, Dan Cojoc, Linh Thuy Lien et al.

 
 

Guidance molecules, such as Sema3A or Netrin-1, induce growth cone (GC) repulsion or attraction. In order to determine the speed of action and efficiency of these guidance cues we …

 
 
 
 
 
 

Cerebrospinal Fluid Metabolome in Mood Disorders-Remission State has a Unique Metabolic Profile

 
 

Rima Kaddurah-Daouk, Peixiong Yuan, Stephen H. Boyle et al.

 
 

Targeted metabolomics provides an approach to quantify metabolites involved in specific molecular pathways. We applied an electrochemistry-based, targeted metabolomics platform to …

 
 
 
 
 
 

Stygoregions – a promising approach to a bioregional classification of groundwater systems

 
 

Heide Stein, Christian Griebler, Sven Berkhoff et al.

 
 

Linked to diverse biological processes, groundwater ecosystems deliver essential services to mankind, the most important of which is the provision of drinking water. In contrast …

 
 
 
 
 
 

Functional integration between defence and IRE1-mediated ER stress response in rice

 
 

Shimpei Hayashi, Yuhya Wakasa, Fumio Takaiwa

 
 

Conditions within the endoplasmic reticulum (ER) influence most secretory proteins that pass through the ER. Therefore, eukaryotic cells must strike a balance between the ER …

 
 
 
 
 
 

A seventh bacterial chlorophyll driving a large light-harvesting antenna

 
 

Jiro Harada, Tadashi Mizoguchi, Yusuke Tsukatani et al.

 
 

The discovery of new chlorophyllous pigments would provide greater understanding of the mechanisms and evolution of photosynthesis. Bacteriochlorophyll f has never been observed …

 
 
 
 
 
 

Integrating multi-origin expression data improves the resolution of deep phylogeny of ray-finned fish (Actinopterygii)

 
 

Ming Zou, Baocheng Guo, Wenjing Tao et al.

 
 

The actinopterygians comprise nearly one-half of all extant vertebrate species and are very important for human well-being. However, the phylogenetic relationships among certain …

 
 
 
 
 
 

Archaeal proteins Nop10 and Gar1 increase the catalytic activity of Cbf5 in pseudouridylating tRNA

 
 

Rajashekhar Kamalampeta, Ute Kothe

 
 

Cbf5 is a pseudouridine synthase that usually acts in a guide RNA-dependent manner as part of H/ACA small ribonucleoproteins; however archaeal Cbf5 can also act independently of …

 
 
 
 
 
 

How to suppress undesired synchronization

 
 

V. H. P. Louzada, N. A. M. Araújo, J. S. Andrade et al.

 
 

Examples of synchronization can be found in a wide range of phenomena such as neurons firing, lasers cascades, chemical reactions, and opinion formation. However, in many …

 
 
 
 
 
 

Production of Graphite Chloride and Bromide Using Microwave Sparks

 
 

Jian Zheng, Hong-Tao Liu, Bin Wu et al.

 
 

Chemically modified graphite is an economical material with promising applications in its own right or as an intermediate in the synthesis of graphene. However, because of its …

 
 
 
 
 
 

A Polycomb complex remains bound through DNA replication in the absence of other eukaryotic proteins

 
 

Bettina M. Lengsfeld, Kayla N. Berry, Sharmistha Ghosh et al.

 
 

Propagation of chromatin states through DNA replication is central to epigenetic regulation and can involve recruitment of chromatin proteins to replicating chromatin through …

 
 
 
 
 
 

Feeder-Free Derivation of Human Induced Pluripotent Stem Cells with Messenger RNA

 
 

Luigi Warren, Yuhui Ni, Jiwu Wang et al.

 
 

The therapeutic promise of induced pluripotent stem cells (iPSCs) has spurred efforts to circumvent genome alteration when reprogramming somatic cells to pluripotency. Approaches …

 
 
 
 
 
 

Decline of forest interior conditions in the conterminous United States

 
 

Kurt H. Riitters, James D. Wickham

 
 

Forest fragmentation threatens the sustainability of forest interior environments, thereby endangering subordinate ecological attributes and functions. We analyzed the spatial …

 
 
 
 
 
 

Stable Isotope Analysis Challenges Wasp-Waist Food Web Assumptions in an Upwelling Pelagic Ecosystem

 
 

Daniel J. Madigan, Aaron B. Carlisle, Heidi Dewar et al.

 
 

Eastern boundary currents are often described as ‘wasp-waist’ ecosystems in which one or few mid-level forage species support a high diversity of larger predators that are highly …

 
 
 
 
 
 

The Cell Cycle Switch Computes Approximate Majority

 
 

Luca Cardelli, Attila Csikász-Nagy

 
 

Both computational and biological systems have to make decisions about switching from one state to another. The ‘Approximate Majority’ computational algorithm provides the …

 
 
 
 
 
 

Regulation of VEGF expression by HIF-1α in the femoral head cartilage following ischemia osteonecrosis

 
 

Chi Zhang, Yang Li, Reuel Cornelia et al.

 
 

Juvenile femoral head osteonecrosis is due to disruption of blood supply which results in ischemic injury. Angiogenesis is an essential component for the healing of damaged head. …

 
 
 
 
 
 

β-hairpin forms by rolling up from C-terminal: Topological guidance of early folding dynamics

 
 

Søren Enemark, Nicholas A. Kurniawan, Raj Rajagopalan

 
 

That protein folding is a non-random, guided process has been known even prior to Levinthal's paradox; yet, guided searches, attendant mechanisms and their relation to primary …

 
 
 
 
 
 

Evolution of cooperation driven by zealots

 
 

Naoki Masuda

 
 

Recent experimental results with humans involved in social dilemma games suggest that cooperation may be a contagious phenomenon and that the selection pressure operating on …

 
 
 
 
 
 

The Fate of a Normal Human Cell Traversed by a Single Charged Particle

 
 

C. Fournier, S. Zahnreich, D. Kraft et al.

 
 

The long-term “fate” of normal human cells after single hits of charged particles is one of the oldest unsolved issues in radiation protection and cellular radiobiology. Using a …

 
 
 
 
 
 

The NAD+-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status

 
 

Xiumei Guo, Mehmet Kesimer, Gökhan Tolun et al.

 
 

SIRT1, a NAD-dependent protein deacetylase, is an important regulator in cellular stress response and energy metabolism. While the list of SIRT1 substrates is growing, how the …

 
 
 
 
 
 

In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues

 
 

Yukiko Nambu, Tatsunari Hayashi, Kyoung-Jin Jang et al.

 
 

Mutually exclusive cell fate determination of CD4 helper or CD8 killer T cells occurs in the thymus. These T-cell subsets are not believed to redirect other lineages. Here we …

 
 
 
 
 
 

A programmable NOR-based device for transcription profile analysis

 
 

Tom Ran, Yehonatan Douek, Lilach Milo et al.

 
 

An autonomous synthetic programmable device that can diagnose a cell's state according to predefined markers and produce a corresponding therapeutic output may be the basis of …

 
 
 
 
 
 

Silencing of microRNA-122 enhances interferon-α signaling in the liver through regulating SOCS3 promoter methylation

 
 

Takeshi Yoshikawa, Akemi Takata, Motoyuki Otsuka et al.

 
 

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide. Although novel drugs against HCV are under development, the current standard therapy …

 
 
 
 
 
 

Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA

 
 

Gabrielle Fredman, Yongsheng Li, Jesmond Dalli et al.

 
 

Mechanisms underlying delays in resolution programs of inflammation are of interest for many diseases. Here, we addressed delayed resolution of inflammation and identified …

 
 
 
 
 
 

Effects of the CACNA1C risk allele on neurocognition in patients with schizophrenia and healthy individuals

 
 

Hiroaki Hori, Noriko Yamamoto, Takashi Fujii et al.

 
 

Recent genetic association studies have identified the A-allele of rs1006737 within CACNA1C as a risk factor for schizophrenia as well as mood disorders. Some evidence suggests …

 
 
 
 
 
 

Targeting the cancer cell cycle by cold atmospheric plasma

 
 

O. Volotskova, T. S. Hawley, M. A. Stepp et al.

 
 

Cold atmospheric plasma (CAP), a technology based on quasi-neutral ionized gas at low temperatures, is currently being evaluated as a new highly selective alternative addition to …

 
 
 
 
 
 

Rapid identification and drug susceptibility screening of ESAT-6 secreting Mycobacteria by a NanoELIwell assay

 
 

Yen H. Nguyen, Xin Ma, Lidong Qin

 
 

To meet the global needs of tuberculosis (TB) control, a nanoELIwell device was developed as a multifunctional assay for TB diagnosis and drug susceptibility testing. The device …

 
 
 
 
 
 

Chemical Structure of Retro-2, a Compound That Protects Cells against Ribosome-Inactivating Proteins

 
 

Jewn Giew Park, Jennifer Nielsen Kahn, Nilgun E. Tumer et al.

 
 

Shiga-like toxins and ricin are ribosome-inactivating proteins (RIPs) that are lethal to mammals and pose a global health threat. No clinical vaccines or therapeutics currently …

 
 
 
 
 
 

Optimizing Functional Network Representation of Multivariate Time Series

 
 

Massimiliano Zanin, Pedro Sousa, David Papo et al.

 
 

By combining complex network theory and data mining techniques, we provide objective criteria for optimization of the functional network representation of generic multivariate …

 
 
 
 
 
 

Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers

 
 

Christopher J. Holland, Pierre J. Rizkallah, Sabrina Vollers et al.

 
 

Successful immunity requires that a limited pool of αβ T-cell receptors (TCRs) provide cover for a vast number of potential foreign peptide antigens presented by ‘self’ major …

 
 
 
 
 
 
 
 
 
 
 
 

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