| |  | | Advertisement |  | |  | | | Special Report from the Euroclonality Consortium: Guidelines for Improved Clonality Diagnostics | Top |  | EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected lymphoproliferationsA W Langerak, P J T A Groenen, M Brüggemann, K Beldjord, C Bellan, L Bonello, E Boone, G I Carter, M Catherwood, F Davi, M-H Delfau-Larue, T Diss, P A S Evans, P Gameiro, R Garcia Sanz, D Gonzalez, D Grand, Å Håkansson, M Hummel, H Liu, L Lombardia, E A Macintyre, B J Milner, S Montes-Moreno, E Schuuring, M Spaargaren, E Hodges and J J M van Dongen Leukemia 2012 26: 2159-2171; advance online publication, August 24, 2012; 10.1038/leu.2012.246 Abstract | Full Text |  | Reviews | Top |  | Standardized definitions of molecular response in chronic myeloid leukemiaN C P Cross, H E White, M C Müller, G Saglio and A Hochhaus Leukemia 2012 26: 2172-2175; advance online publication, April 16, 2012; 10.1038/leu.2012.104 Abstract | Full Text |  |  |  | Targeting the FMS-like tyrosine kinase 3 in acute myeloid leukemiaR Swords, C Freeman and F Giles Leukemia 2012 26: 2176-2185; advance online publication, April 27, 2012; 10.1038/leu.2012.114 Abstract | Full Text |  |  |  | Leukemia-associated antigens and their relevance to the immunotherapy of acute myeloid leukemiaS Anguille, V F Van Tendeloo and Z N Berneman Leukemia 2012 26: 2186-2196; advance online publication, June 1, 2012; 10.1038/leu.2012.145 Abstract | Full Text |  | Original Articles | Top |  | THERAPY | Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-upR A Larson, A Hochhaus, T P Hughes, R E Clark, G Etienne, D-W Kim, I W Flinn, M Kurokawa, B Moiraghi, R Yu, R E Blakesley, N J Gallagher, G Saglio and H M Kantarjian Leukemia 2012 26: 2197-2203; advance online publication, May 18, 2012; 10.1038/leu.2012.134 Abstract | Full Text |  |  |  | ACUTE LEUKEMIAS | Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrationsT D Buitenkamp, R Pieters, N E Gallimore, A van der Veer, J P P Meijerink, H B Beverloo, M Zimmermann, V de Haas, S M Richards, A J Vora, C D Mitchell, L J Russell, C Schwab, C J Harrison, A V Moorman, M M van den Heuvel-Eibrink, M L den Boer and C M Zwaan Leukemia 2012 26: 2204-2211; advance online publication, March 22, 2012; 10.1038/leu.2012.84 Abstract | Full Text |  |  |  | Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemiaV Enciso-Mora, F J Hosking, E Sheridan, S E Kinsey, T Lightfoot, E Roman, J A E Irving, I P M Tomlinson, J M Allan, M Taylor, M Greaves and R S Houlston Leukemia 2012 26: 2212-2215; advance online publication, March 29, 2012; 10.1038/leu.2012.89 Abstract | Full Text |  |  |  | TET2 is essential for survival and hematopoietic stem cell homeostasisK Shide, T Kameda, H Shimoda, T Yamaji, H Abe, A Kamiunten, M Sekine, T Hidaka, K Katayose, Y Kubuki, S Yamamoto, T Miike, H Iwakiri, S Hasuike, K Nagata, K Marutsuka, A Iwama, T Matsuda, A Kitanaka and K Shimoda Leukemia 2012 26: 2216-2223; advance online publication, April 3, 2012; 10.1038/leu.2012.94 Abstract | Full Text |  |  |  | B-cell regulator of immunoglobulin heavy-chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cellsM P Puissegur, R Eichner, C Quelen, E Coyaud, B Mari, K Lebrigand, C Broccardo, F Nguyen-Khac, M Bousquet and P Brousset Leukemia 2012 26: 2224-2232; advance online publication, April 3, 2012; 10.1038/leu.2012.95 Abstract | Full Text |  |  |  | Using combination therapy to override stromal-mediated chemoresistance in mutant FLT3-positive AML: synergism between FLT3 inhibitors, dasatinib/multi-targeted inhibitors and JAK inhibitorsE Weisberg, Q Liu, Erik Nelson, A L Kung, A L Christie, R Bronson, M Sattler, T Sanda, Z Zhao, W Hur, C Mitsiades, R Smith, J F Daley, R Stone, I Galinsky, J D Griffin and N Gray Leukemia 2012 26: 2233-2244; advance online publication, April 3, 2012; 10.1038/leu.2012.96 Abstract | Full Text |  |  |  | Poor prognosis for P2RY8-CRLF2 fusion but not for CRLF2 over-expression in children with intermediate risk B-cell precursor acute lymphoblastic leukemiaC Palmi, E Vendramini, D Silvestri, G Longinotti, D Frison, G Cario, C Shochat, M Stanulla, V Rossi, A M Di Meglio, T Villa, E Giarin, G Fazio, A Leszl, M Schrappe, G Basso, A Biondi, S Izraeli, V Conter, M G Valsecchi, G Cazzaniga and G te Kronnie Leukemia 2012 26: 2245-2253; advance online publication, April 9, 2012; 10.1038/leu.2012.101 Abstract | Full Text |  |  |  | CHRONIC MYELOPROLIFERATIVE NEOPLASIAS | First-line imatinib mesylate in patients with newly diagnosed accelerated phase-chronic myeloid leukemiaD Rea, G Etienne, F Nicolini, P Cony-Makhoul, H Johnson-Ansah, L Legros, F Huguet, M Tulliez, M Gardembas, K Bouabdallah, P Rousselot, J-M Cayuela, F Guilhot and F-X Mahon Leukemia 2012 26: 2254-2259; advance online publication, March 30, 2012; 10.1038/leu.2012.92 Abstract | Full Text |  |  |  | CHRONIC LYMPHOCYTIC LEUKEMIA | N-(4-hydroxyphenyl)retinamide promotes apoptosis of resting and proliferating B-cell chronic lymphocytic leukemia cells and potentiates fludarabine and ABT-737 cytotoxicityS Bruno, F Ghiotto, C Tenca, A N Mazzarello, M Bono, P Luzzi, S Casciaro, A Recchia, A DeCensi, F Morabito and F Fais Leukemia 2012 26: 2260-2268; advance online publication, April 5, 2012; 10.1038/leu.2012.98 Abstract | Full Text |  |  |  | LYMPHOMA | Mast cells promote the growth of Hodgkin's lymphoma cell tumor by modifying the tumor microenvironment that can be perturbed by bortezomibH Mizuno, T Nakayama, Y Miyata, S Saito, S Nishiwaki, N Nakao, K Takeshita and T Naoe Leukemia 2012 26: 2269-2276; advance online publication, March 20, 2012; 10.1038/leu.2012.81 Abstract | Full Text |  |  |  | E2F4 plays a key role in Burkitt lymphoma tumorigenesisI Molina-Privado, R Jiménez-P, S Montes-Moreno, Y Chiodo, M Rodríguez-Martínez, L Sánchez-Verde, T Iglesias, M A Piris and M R Campanero Leukemia 2012 26: 2277-2285; advance online publication, April 5, 2012; 10.1038/leu.2012.99 Abstract | Full Text |  |  |  | MYELOMA | Increased expression of extracellular matrix metalloproteinase inducer (CD147) in multiple myeloma: role in regulation of myeloma cell proliferationB K Arendt, D K Walters, X Wu, R C Tschumper, P M Huddleston, K J Henderson, A Dispenzieri and D F Jelinek Leukemia 2012 26: 2286-2296; advance online publication, March 30, 2012; 10.1038/leu.2012.91 Abstract | Full Text |  | Letters to the Editor | Top |  | Fas expression at diagnosis as a biomarker of azacitidine activity in high-risk MDS and secondary AMLS Ettou, E Audureau, C Humbrecht, B Benet, H Jammes, T Clozel, V Bardet, C Lacombe, F Dreyfus, P Mayeux, E Solary and M Fontenay Leukemia 2012 26: 2297-2299; advance online publication, June 5, 2012; 10.1038/leu.2012.152 Full Text |  |  |  | Impact of bivaluridin and Genous stent in patients with acute myeloid leukemia undergoing emergency percutaneous coronary angioplasty for acute coronary syndromeG Galasso, T Niglio, S De Luca, C De Biase, V Parisi and F Piscione Leukemia 2012 26: 2300-2301; advance online publication, April 2, 2012; 10.1038/leu.2012.93 Full Text |  | Corrigenda | Top |  | Generation and characterization of a novel hematopoietic progenitor cell line with DC differentiation potentialC Rathinam, M Sauer, A Ghosh, C Rudolph, A Hegazy, B Schlegelberger, K Welte and C Klein Leukemia 2012 26: 2302; 10.1038/leu.2012.132 Abstract | Full Text |  |  |  | Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-upR A Larson, A Hochhaus, T P Hughes, R E Clark, G Etienne, D-W Kim, I W Flinn, M Kurokawa, B Moiraghi, R Yu, R E Blakesley, N J Gallagher, G Saglio and H M Kantarjian Leukemia 2012 26: 2302; 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