Clinical Pharmacology and Therapeutics - Table of Contents alert Volume 92 Issue 5

TABLE OF CONTENTS Volume 92, Issue 5 (November 2012) In this issue In This Issue Editorial News & Views Perspectives Translation Development Clinical Trial State of the Art Reviews Research Discovery Corrigendum Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement Weekly content now available Open Access - Peer Review - Renowned International Editorial Board Newly launched, CPT: PSP publishes weekly content covering the latest advances in quantitative methods as applied in pharmacology, physiology, and therapeutics in humans with a common focus on the application of these two areas on drug development.   In This Issue Top In This Issue Clin Pharmacol Ther 2012 92: 529; 10.1038/clpt.2012.174 Full Text Editorial Top Drug Trafficking: Recent Advances in Therapeutics and Disease J A Sprowl and A Sparreboom Clin Pharmacol Ther 2012 92: 531-534; 10.1038/clpt.2012.167 Abstract | Full Text Advancing Pharmacometrics and Systems Pharmacology S A Waldman and A Terzic Clin Pharmacol Ther 2012 92: 535-537; 10.1038/clpt.2012.151 Abstract | Full Text News & Views Top Highlights Clin Pharmacol Ther 2012 92: 538-539; 10.1038/clpt.2012.173 Full Text ASCPT News Clin Pharmacol Ther 2012 92: 540-544; 10.1038/clpt.2012.169 Full Text Perspectives Top COMMENTARIES The UCSF-FDA TransPortal: A Public Drug Transporter Database K M Morrissey, C C Wen, S J Johns, L Zhang, S-M Huang and K M Giacomini Clin Pharmacol Ther 2012 92: 545-546; 10.1038/clpt.2012.44 Abstract | Full Text Prediction of Transporter-Mediated Drug–Drug Interactions Using Endogenous Compounds M F Fromm Clin Pharmacol Ther 2012 92: 546-548; 10.1038/clpt.2012.145 Abstract | Full Text Models of Excellence: Improving Oncology Drug Development M R Sharma, M L Maitland and M J Ratain Clin Pharmacol Ther 2012 92: 548-550; 10.1038/clpt.2012.99 Abstract | Full Text A Step Closer to Personalized Chemotherapy: Consideration of the Influence of Genetic Variation in Hepatic Uptake Transporters on the Metabolism of CYP3A Substrates L Z Benet Clin Pharmacol Ther 2012 92: 551-552; 10.1038/clpt.2012.165 Abstract | Full Text CONFERENCE PROCEEDINGS Highlights from the International Transporter Consortium Second Workshop M J Zamek-Gliszczynski, K A Hoffmaster, D J Tweedie, K M Giacomini and K M Hillgren Clin Pharmacol Ther 2012 92: 553-556; 10.1038/clpt.2012.126 Abstract | Full Text LETTERS TO THE EDITOR High-Dose Ibuprofen Therapy for Patent Ductus Arteriosus in Extremely Preterm Neonates: Do We Have a Final Answer? S Sajan Saini and V Mahajan Clin Pharmacol Ther 2012 92: 557; advance online publication, September 12, 2012; 10.1038/clpt.2012.150 Full Text Response to “High-Dose Ibuprofen Therapy for Patent Ductus Arteriosus in Extremely Preterm Neonates: Do We Have a Final Answer?” C Dani Clin Pharmacol Ther 2012 92: 558; advance online publication, October 3, 2012; 10.1038/clpt.2012.162 Full Text Translation Top Hepatocyte Hopping of OATP1B Substrates Contributes to Efficient Hepatic Detoxification D Iusuf, E van de Steeg and A H Schinkel Clin Pharmacol Ther 2012 92: 559-562; advance online publication, September 26, 2012; 10.1038/clpt.2012.143 Full Text A Clinician-Driven Automated System for Integration of Pharmacogenetic Interpretations Into an Electronic Medical Record J K Hicks, K R Crews, J M Hoffman, N M Kornegay, M R Wilkinson, R Lorier, A Stoddard, W Yang, C Smith, C A Fernandez, S J Cross, C Haidar, D K Baker, S C Howard, W E Evans, U Broeckel and M V Relling Clin Pharmacol Ther 2012 92: 563-566; advance online publication, September 19, 2012; 10.1038/clpt.2012.140 Full Text Development Top Zebrafish as a Model to Study Drug Transporters at the Blood–Brain Barrier R A Umans and M R Taylor Clin Pharmacol Ther 2012 92: 567-570; advance online publication, October 10, 2012; 10.1038/clpt.2012.168 Full Text Use of Healthy Volunteers Drives Clinical Oncology Drug Development Decision Making M Iwamoto, R Iannone and J A Wagner Clin Pharmacol Ther 2012 92: 571-574; advance online publication, September 26, 2012; 10.1038/clpt.2012.157 Full Text Clinical Trial Top Effect of Adherence as Measured by MEMS, Ritonavir Boosting, and CYP3A5 Genotype on Atazanavir Pharmacokinetics in Treatment-Naive HIV-Infected Patients R M Savic, A Barrail-Tran, X Duval, G Nembot, X Panhard, D Descamps, C Verstuyft, B Vrijens, A-M Taburet, C Goujard and F Mentré and the ANRS 134–COPHAR 3 Study Group Clin Pharmacol Ther 2012 92: 575-583; advance online publication, October 3, 2012; 10.1038/clpt.2012.137 Abstract | Full Text State of the Art Top Understanding the Critical Disposition Pathways of Statins to Assess Drug–Drug Interaction Risk During Drug Development: It's Not Just About OATP1B1 R Elsby, C Hilgendorf and K Fenner Clin Pharmacol Ther 2012 92: 584-598; advance online publication, October 10, 2012; 10.1038/clpt.2012.163 Abstract | Full Text A Perspective on Efflux Transport Proteins in the Liver K Köck and K L R Brouwer Clin Pharmacol Ther 2012 92: 599-612; advance online publication, September 5, 2012; 10.1038/clpt.2012.79 Abstract | Full Text Reviews Top REVIEW The TGF-β Pathway as an Emerging Target for Chagas Disease Therapy T C Araújo-Jorge, M C Waghabi, S Bailly and J-J Feige Clin Pharmacol Ther 2012 92: 613-621; advance online publication, September 19, 2012; 10.1038/clpt.2012.102 Abstract | Full Text Fruit Juices as Perpetrators of Drug Interactions: The Role of Organic Anion–Transporting Polypeptides M J Dolton, B D Roufogalis and A J McLachlan Clin Pharmacol Ther 2012 92: 622-630; advance online publication, October 3, 2012; 10.1038/clpt.2012.159 Abstract | Full Text Research Top REPORTS Simulations Using a Drug–Disease Modeling Framework and Phase II Data Predict Phase III Survival Outcome in First-Line Non–Small-Cell Lung Cancer L Claret, J-F Lu, R Bruno, C-P Hsu, Y-J Hei and Y-N Sun Clin Pharmacol Ther 2012 92: 631-634; advance online publication, August 22, 2012; 10.1038/clpt.2012.78 Abstract | Full Text ARTICLES N-Methylnicotinamide Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving Multidrug and Toxin Extrusions (MATE1 and MATE2-K) S Ito, H Kusuhara, Y Kumagai, Y Moriyama, K Inoue, T Kondo, H Nakayama, S Horita, K Tanabe, H Yuasa and Y Sugiyama Clin Pharmacol Ther 2012 92: 635-641; advance online publication, October 10, 2012; 10.1038/clpt.2012.138 Abstract | Full Text OATP1B1 Polymorphism as a Determinant of Erythromycin Disposition C S Lancaster, G H Bruun, C J Peer, T S Mikkelsen, T J Corydon, A A Gibson, S Hu, S J Orwick, R H J Mathijssen, W D Figg, S D Baker and A Sparreboom Clin Pharmacol Ther 2012 92: 642-650; advance online publication, September 19, 2012; 10.1038/clpt.2012.106 Abstract | Full Text Pomegranate Juice and Pomegranate Extract Do Not Impair Oral Clearance of Flurbiprofen in Human Volunteers: Divergence From In Vitro Results M J Hanley, G Masse, J S Harmatz, M H Court and D J Greenblatt Clin Pharmacol Ther 2012 92: 651-657; advance online publication, October 10, 2012; 10.1038/clpt.2012.170 Abstract | Full Text Discovery Top Contribution of the OATP1B Subfamily to Cancer Biology and Treatment T M Sissung, K M Reece, S Spencer and W D Figg Clin Pharmacol Ther 2012 92: 658-660; advance online publication, September 26, 2012; 10.1038/clpt.2012.127 Full Text Computational Modeling to Accelerate the Identification of Substrates and Inhibitors for Transporters That Affect Drug Disposition S Ekins, J E Polli, P W Swaan and S H Wright Clin Pharmacol Ther 2012 92: 661-665; advance online publication, September 26, 2012; 10.1038/clpt.2012.164 Full Text Corrigendum Top Corrigendum: Models for Disease Progression: New Approaches and Uses Clin Pharmacol Ther 2012 92: 666; 10.1038/clpt.2012.155 Full Text   Advertisement Ensure your access If you are unable to access the articles in thisalert, your library may not subscribe to this journal. Our online recommendation form is a simple way to make your librarian aware that this journal is valuable to your research. Recommend now at http://www.nature.com/librec/svc/request/makeProdRequest?id=clpt   Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Clinical Pharmacology & Therapeutics. In order to do so, please purchase a subscription. You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. For other enquiries, please contact our customer feedback department. Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2012 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.