Friday, September 7, 2012

Symphogen licenses experimental cancer drug to Merck

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September 7, 2012
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  Today's Top Story 
  • Symphogen licenses experimental cancer drug to Merck
    Merck KGaA secured exclusive worldwide development rights to Symphogen's Sym004, an anti-EGFR, dual-antibody mixture undergoing clinical trials for advanced KRAS wild-type metastatic colorectal cancer and squamous cell carcinoma of the head and neck. The licensing deal entitles Symphogen to about $25 million upfront plus as much $283 million in clinical development and regulatory milestone payments and about $314 million in potential sales milestone fees and royalties. Genetic Engineering & Biotechnology News (9/6) LinkedInFacebookTwitterEmail this Story
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  Health Care & Policy 
  • Astex teams up with U.K. groups to develop blood cancer treatments
    Astex Pharmaceuticals, the U.K.-based Cancer Research Technology and the Institute of Cancer Research agreed to work together to discover and develop drug candidates against a certain epigenetic target for blood cancer. The collaboration will integrate Astex's drug discovery technology and epigenetic drug development expertise with the institute's knowledge in blood cancer biology and drug discovery know-how. Genetic Engineering & Biotechnology News (9/6) LinkedInFacebookTwitterEmail this Story
  • ImaginAb to develop imaging agents for MacroGenics
    ImaginAb has entered a deal to develop imaging agents to be used in conjunction with a cancer drug being developed by MacroGenics. ImaginAb will develop agents for B7-H3, an immune regulator target that MacroGenics is using to develop the treatment. ImaginAb will also use a MacroGenics anti-CD3 antibody to develop a patient-selection tool for ongoing clinical trials. GenomeWeb Daily News (free registration) (9/5) LinkedInFacebookTwitterEmail this Story
  Company & Financial News 
  • Zymeworks obtains $11M in financing, gets milestone pay from Merck
    Zymeworks, which develops bispecific antibody drugs, raised an additional $11 million in venture capital from angel investors. The firm will use the money to develop an internal cancer drug candidate, which it hopes to bring into clinical study by late 2014. Zymeworks also received a cash payment from Merck & Co. after achieving a technical milestone linked to their collaboration. Xconomy/Seattle (9/6) LinkedInFacebookTwitterEmail this Story
  Featured Content 
 

  Food & Agriculture 
  • EU court: Member nations can't ban EU-approved biotech crops
    Member nations can't block the cultivation of biotech crops approved by the European Union, the European Court of Justice ruled in a case involving Pioneer Hi-Bred Italia and the Italian agriculture ministry. A lack of policies to ensure co-existence between biotech, organic and traditional crops doesn't give a member state the right to ban biotech crops, the court said. Bloomberg (9/6) LinkedInFacebookTwitterEmail this Story
  Industrial & Environmental 
  • Study looks at biofuel potential of nonflowering switchgrass
    Introducing a gene from corn into switchgrass would inhibit its maturation, allowing it to store more starch for conversion into cellulosic ethanol, according to scientists with the USDA's Agricultural Research Service and the University of California at Berkeley. Nonflowering varieties of switchgrass could boost starch content by 250%, said Sarah Hake, an ARS geneticist. Agriculture Research Service (USDA) (9/2012) LinkedInFacebookTwitterEmail this Story
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