Wednesday, September 5, 2012

Pfizer's leukemia drug Bosulif gains FDA approval

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September 5, 2012
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  Health Care & Policy 
  • CVR buyback indicates Sanofi's growing confidence in Lemtrada
    Sanofi plans to repurchase as much as $152 million worth of outstanding contingent-value rights related to the success of drugs developed by Genzyme, which it acquired last year. The plan is a sign of Sanofi's increasing confidence in multiple sclerosis drug Lemtrada, or alemtuzumab, which is waiting for regulatory approval and could enter the market next year. Reuters (9/4) LinkedInFacebookTwitterEmail this Story
  • Biokine licenses leukemia drug candidate to BioLineRX
    Biokine Therapeutics granted BioLineRx exclusive worldwide rights to BL-8040, a therapeutic peptide for acute myeloid leukemia and other hematologic cancers. As part of the licensing deal, Biokine will receive $50,000 to $100,000 a month in exchange for certain development services and $250,000 in potential milestone fees plus royalties if the drug is sublicensed to a third party. BioLineRx plans to initiate a midstage trial next year to assess the efficacy of the peptide in AML patients. Genetic Engineering & Biotechnology News (9/4) LinkedInFacebookTwitterEmail this Story
  • ImmusanT's celiac vaccine Nexvax2 enters early-stage development
    ImmusanT initiated two early-stage trials of Nexvax2, a celiac disease vaccine designed to help patients develop tolerance to gluten, which damages the lining of their small intestines. One trial, conducted in Australia and New Zealand, will evaluate tolerability, safety and pharmacokinetics in patients on a gluten-free diet. The other study is in the U.S. Mass High Tech (Boston) (9/4) LinkedInFacebookTwitterEmail this Story
  • Neural stem cells help return sensation to patients with paralysis
    Swiss researchers are testing the use of neural stem cells in the treatment of three patients with broken spines. After six months, two of the patients reported sensations of touch and heat between the chest and belly button, according to the findings presented at a spinal cord society meeting. Nine more patients are set to receive the treatment. New Scientist (9/3) LinkedInFacebookTwitterEmail this Story
  • Collaborative study will look at circulating tumor cells
    NYU Langone Medical Center and Transgenomic will collaborate on research to detect mutations in circulating tumor cells of patients with early-stage lung cancer in an effort to personalize treatment. Researchers will compare the genetic profiles of cell-free DNA with CTC DNA to provide new insights into the genetic makeup of metastasizing tumor cells and to identify mutations known to respond to treatment. Genetic Engineering & Biotechnology News (9/4) LinkedInFacebookTwitterEmail this Story
  Company & Financial News 
 
  • Cellerant gets $36.4M for stem cell-based radiation syndrome therapy
    The Biomedical Advanced Research and Development Authority awarded Cellerant Therapeutics a $36.4 million grant to help further develop CLT-008, an allogeneic stem cell-based treatment for acute radiation syndrome. The funding is part of a five-year grant that could total $169.9 million. Cellerant will put the money toward ongoing clinical and nonclinical studies, as well as process development and manufacturing. Genetic Engineering & Biotechnology News (9/4) LinkedInFacebookTwitterEmail this Story

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  • BIO, 6 groups move to intervene in RFS lawsuit
    BIO and six other groups are seeking to intervene in a lawsuit brought by an oil-industry group against the 2012 cellulosic and advanced biofuel targets under the Renewable Fuel Standard. In a brief filed Tuesday, the groups said the Environmental Protection Agency's 2012 cellulosic and advance biofuels targets are based on market projections and in keeping with rules set by Congress. "Precedent makes clear that EPA can adopt standards calculated to spur development, consistent with Congress's express statutory objectives," the groups' filing showed. DomesticFuel.com (9/4) LinkedInFacebookTwitterEmail this Story
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