| | | | Weekly Content Alert
| | 11 September 2012 | | Featured image: | | | | Lee et al. present a microscopic setup that allows confocal imaging of a beating mouse heart in real time. |
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| | | Advertisement | | | | | | Latest Articles | View all Articles | | | Evidence of an inhibitory restraint of seizure activity in humans | | Catherine A. Schevon, Shennan A. Weiss, Guy McKhann , Jr, Robert R. Goodman, Rafael Yuste, Ronald G. Emerson and Andrew J. Trevelyan | | Seizure activity in the brain is characterized by the recruitment of cortical neuronal activity. Schevon and colleagues study seizure activity in human subjects and find that the recruitment of neurons is hypersynchronous and that there is an intrinsic restraint on the propagation of this activity. | | 11 Sep | Nat Commun 3:1060 doi:10.1038/ncomms2056 (2012) | | Biological sciences Medical research Neuroscience | | Abstract | Full Text | PDF (1,748 kB) | Supplementary Information |
Greatwall kinase and cyclin B-Cdk1 are both critical constituents of M-phase-promoting factor OPEN | | Masatoshi Hara, Yusuke Abe, Toshiaki Tanaka, Takayoshi Yamamoto, Eiichi Okumura and Takeo Kishimoto | | Cyclin B–Cdk1 is thought to be synonymous with the promoting factor that drives entry into M-phase of the cell cycle. Here, Greatwall kinase is shown to be required for the breakdown of the nuclear envelope and the assembly of the spindle on entry into M-phase, suggesting that it too is a part of the M-phase-promoting factor. | | 11 Sep | Nat Commun 3:1059 doi:10.1038/ncomms2062 (2012) | | Biological sciences Cell biology | | | | Abstract | Full Text | PDF (845 kB) | Supplementary Information |
The spin Hall effect as a probe of nonlinear spin fluctuations | | D.H. Wei, Y. Niimi, B. Gu, T. Ziman, S. Maekawa and Y. Otani | | The spin Hall effect and its inverse allow conversion between charge and spin currents in both magnetic and nonmagnetic materials. Wei et al. observe an anomaly in the temperature dependence of the inverse spin Hall effect, which suggests that it can also be used as a sensor for very small magnetic moments. | | 11 Sep | Nat Commun 3:1058 doi:10.1038/ncomms2063 (2012) | | Physical sciences Applied physics | | Condensed matter | | Abstract | Full Text | PDF (768 kB) | Supplementary Information |
Fabrication of flexible and freestanding zinc chalcogenide single layers | | Yongfu Sun, Zhihu Sun, Shan Gao, Hao Cheng, Qinghua Liu, Junyu Piao, Tao Yao, Changzheng Wu, Shuanglin Hu, Shiqiang Wei and Yi Xie | | Ultrathin inorganic materials hold promise for a variety of applications, including flexible electronics. This work presents a fabrication method that permits the synthesis of large and flexible freestanding layers of zinc selenide that display a high-photocurrent density. | | 11 Sep | Nat Commun 3:1057 doi:10.1038/ncomms2066 (2012) | | Chemical sciences Inorganic chemistry | | Materials science | | Abstract | Full Text | PDF (826 kB) | Supplementary Information |
Proximity-induced high-temperature superconductivity in the topological insulators Bi2Se3 and Bi2Te3 | | Parisa Zareapour, Alex Hayat, Shu Yang F. Zhao, Michael Kreshchuk, Achint Jain, Daniel C. Kwok, Nara Lee, Sang-Wook Cheong, Zhijun Xu, Alina Yang, G.D. Gu, Shuang Jia, Robert J. Cava and Kenneth S. Burch | | Inducing superconductivity in topological insulators by proximity to superconductors is a promising strategy for quantum computing. Here the authors induce high-temperature superconductivity in the topological insulators Bi2Se3 and Bi2Te3 by placing them in contact with a cuprate superconductor. | | 11 Sep | Nat Commun 3:1056 doi:10.1038/ncomms2042 (2012) | | Physical sciences Condensed matter | | Materials science | | Abstract | Full Text | PDF (683 kB) | Supplementary Information |
TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer | | Alejandra Bruna, Wendy Greenwood, John Le Quesne, Andrew Teschendorff, Diego Miranda-Saavedra, Oscar M. Rueda, Jose L. Sandoval, Ana Tufegdzic Vidakovic, Amel Saadi, Paul Pharoah, John Stingl and Carlos Caldas | | TGF-β signalling suppresses tumorigenesis in breast cancer cells but its effects on breast cancer initiating cells have not been reported. Using cells in culture, Bruna et al. show that TGF-β increases breast cancer initiating cell numbers in cells that have low levels of the tight junction protein claudin. | | 11 Sep | Nat Commun 3:1055 doi:10.1038/ncomms2039 (2012) | | Biological sciences Cancer | | Cell biology | | Abstract | Full Text | PDF (1,128 kB) | Supplementary Information |
Real-time in vivo imaging of the beating mouse heart at microscopic resolution | | Sungon Lee, Claudio Vinegoni, Paolo Fumene Feruglio, Lyuba Fexon, Rostic Gorbatov, Misha Pivoravov, Andrea Sbarbati, Matthias Nahrendorf and Ralph Weissleder | | Microscopic imaging techniques have a high spatio-temporal resolution but, in living animals, are hampered by cardiac and respiratory motion. This paper describes a microscopic setup that allows fluorescent confocal imaging of the beating mouse heart over a period of several hours. | | 11 Sep | Nat Commun 3:1054 doi:10.1038/ncomms2060 (2012) | | Biological sciences | | Abstract | Full Text | PDF (979 kB) | Supplementary Information |
High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring OPEN | | Sonia de Assis, Anni Warri, M. Idalia Cruz, Olusola Laja, Ye Tian, Bai Zhang, Yue Wang, Tim Hui-Ming Huang and Leena Hilakivi-Clarke | | Environmental factors can influence one's susceptibility to cancer, but it is not clear whether such an influence extends beyond the directly exposed generations. Here, feeding pregnant rats with a high-fat diet or a hormone derivative, the authors observe increased breast cancer risk in up to three subsequent generations. | | 11 Sep | Nat Commun 3:1053 doi:10.1038/ncomms2058 (2012) | | Biological sciences Cancer | | Developmental biology Molecular biology | | Abstract | Full Text | PDF (985 kB) | Supplementary Information |
Enhanced mechanical properties of nanocrystalline boron carbide by nanoporosity and interface phases | | K. Madhav Reddy, J.J. Guo, Y. Shinoda, T. Fujita, A. Hirata, J.P. Singh, J.W. McCauley and M.W. Chen | | The mechanical properties of structural ceramics are characterized by a high degree of fragility and brittleness. This study demonstrates that, contrary to expectation, their brittleness can be reduced substantially by introducing nanopores together with weak grain boundary phases. | | 11 Sep | Nat Commun 3:1052 doi:10.1038/ncomms2047 (2012) | | Physical sciences Applied physics | | Materials science | | Nanotechnology | | Abstract | Full Text | PDF (1,341 kB) | Supplementary Information |
Attention gates visual coding in the human pulvinar | | Jason Fischer and David Whitney | | The pulvinar nucleus is involved in modulating visual information. Fischer and Whitney use brain imaging to study the pulvinar during visual attention, and find that the positions and orientations of attended objects are precisely encoded in the pulvinar, while information about ignored objects is gated out. | | 11 Sep | Nat Commun 3:1051 doi:10.1038/ncomms2054 (2012) | | Biological sciences Neuroscience | | | | Abstract | Full Text | PDF (869 kB) | Supplementary Information |
A non-syn-gas catalytic route to methanol production | | Cheng-Tar Wu, Kai Man Kerry Yu, Fenglin Liao, Neil Young, Peter Nellist, Andrew Dent, Anna Kroner and Shik Chi Edman Tsang | | Methanol is an important industrial chemical and liquid fuel, and is usually produced by the syn-gas route from natural gas. Wu et al. develop a new catalytic process that directly converts ethylene glycol, derived from biomass or fossil fuels, to methanol in hydrogen using a Pd/Fe2O3 co-precipitated catalyst. | | 11 Sep | Nat Commun 3:1050 doi:10.1038/ncomms2053 (2012) | | Chemical sciences Catalysis | | Inorganic chemistry | | Abstract | Full Text | PDF (1,004 kB) | Supplementary Information |
Disruption of a proto-planetary disc by the black hole at the milky way centre | | Ruth A. Murray-Clay and Abraham Loeb | | Recent observations have uncovered a cloud of ionized gas falling into the supermassive black hole at the centre of our galaxy. Murray-Clay and Loeb present a model that may explain these observations, in which the cloud is produced from the proto-planetary disc around a low-mass star orbiting the black hole. | | 11 Sep | Nat Commun 3:1049 doi:10.1038/ncomms2044 (2012) | | Physical sciences Astronomy | | | | Abstract | Full Text | PDF (372 kB) | Supplementary Information |
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