Molecular Systems Biology - New articles published 11 September 2012

Latest Articles 11th September 2012   Featured Article Research Articles Editorial Correspondence Advertisement ACCELERATE YOUR RESEARCH: Save time & money for your project with our services to: - DISCOVER novel protein interactions; - VALIDATE protein functions in cell; - INHIBIT protein interactions with small molecules. Benefit from our expertise in protein interactions and get high-quality results. Over 200 publications in top-ranking journals and 1,000 researchers who trusted us. www.hybrigenics-services.com +33 (0)1 58 10 38 29     Web feeds About Open access Advertisement Molecular Systems Biology is seeking for an editor to join its in-house editorial team. This is an exciting opportunity to launch an editorial career with a leading journal in the fields of systems biology, synthetic biology and systems medicine. Work on all aspects of the editorial process including critically reading submitted research, organizing peer review, commissioning reviews, & developing journal content and editorial policies. Shape your field, join our team! Apply here: http://bit.ly/RhOEiN   Featured Article Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma In-depth proteomic analysis of microdissected colorectal cancer identifies extensive alterations in the cell-surface and nuclear proteomes between normal mucosa and adenocarcinoma, but observes strikingly little proteomic change between cancer and metastases. Jacek R Wiśniewski, Paweł Ostasiewicz, Kamila Duś, Dorota F Zielińska, Florian Gnad & Matthias Mann Molecular Systems Biology 8:611; doi:10.1038/msb.2012.44; published 11 September 2012 Full Text | PDF | Supp. Inf. | Review Process Research Articles Gene location and DNA density determine transcription factor distributions in Escherichia coli The steady-state spatial distribution of the lac repressor transcription factor is found to depend on the location of the encoding gene and the compaction of the surrounding DNA. This has important implications for global gene regulation and genome organization. Thomas E Kuhlman & Edward C Cox Molecular Systems Biology 8:610; doi:10.1038/msb.2012.42; published 11 September 2012 Full Text | PDF | Supp. Inf. | Review Process Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells Genomic, transcriptomic and proteomic profiles of human aneuploid cells reveal that mRNA levels increase with gene copy number, but protein levels are partially compensated. Aneuploid cells also exhibit common alterations in several pathways, including an activation of autophagy. Silvia Stingele, Gabriele Stoehr, Karolina Peplowska, Jürgen Cox, Matthias Mann & Zuzana Storchova Molecular Systems Biology 8:608; doi:10.1038/msb.2012.40; published 11 September 2012 Full Text | PDF | Supp. Inf. | Review Process Editorial The changing privacy landscape in the era of big data Eric E Schadt Molecular Systems Biology 8:612; doi:10.1038/msb.2012.47; published 11 September 2012 Full Text | PDF Correspondence A feel for systems Eberhard O Voit, Wendy C Newstetter & Melissa L Kemp Molecular Systems Biology 8:609; doi:10.1038/msb.2012.41; published 11 September 2012 Full Text | PDF | Supp. Inf.

Advertisement

Systems Biology Data Resources Deciphering a global network of functionally associated post-translational modifications Pablo Minguez, Peer Bork and colleagues Access the data Single-cell analysis of population context advances RNAi screening at multiple levels Berend Snijder, Lucas Pelkman and colleagues Access the data Effects of diet and development on the Drosophila lipidome Maria Carvalho, Andrej Shevchenko and colleagues Access the data

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. For other enquiries, please contact our customer feedback department. Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2012 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.