Wednesday, August 8, 2012

Leukemia - Table of Contents alert Volume 26 Issue 8

TABLE OF CONTENTS

Volume 26, Issue 8 (August 2012)

In this issue
How to Manage…
Original Articles
Letters to the Editor

Also new
AOP

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How to Manage…

Top

How to manage acute promyelocytic leukemia

J-Q Mi, J-M Li, Z-X Shen, S-J Chen and Z Chen

Leukemia 2012 26: 1743-1751; advance online publication, March 16, 2012; 10.1038/leu.2012.57

Abstract | Full Text

Original Articles

Top

MOLECULAR TARGETS FOR THERAPY

Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells

Y Yu, L Yang, M Zhao, S Zhu, R Kang, P Vernon, D Tang and L Cao

Leukemia 2012 26: 1752-1760; advance online publication, March 7, 2012; 10.1038/leu.2012.65

Abstract | Full Text

Optimal induction of myeloma cell death requires dual blockade of phosphoinositide 3-kinase and mTOR signalling and is determined by translocation subtype

C Stengel, C W Cheung, J Quinn, K Yong and A Khwaja

Leukemia 2012 26: 1761-1770; advance online publication, March 14, 2012; 10.1038/leu.2012.69

Abstract | Full Text

THERAPY

Serial monitoring of human systemic and xenograft models of leukemia using a novel vascular disrupting agent

M Benezra, E Phillips, D Tilki, B-S Ding, J Butler, K Dobrenkov, B Siim, D Chaplin, S Rafii, S Rabbany and M S Bradbury

Leukemia 2012 26: 1771-1778; advance online publication, February 20, 2012; 10.1038/leu.2012.48

Abstract | Full Text

Outcome of patients activating an unrelated donor search: the impact of transplant with reduced intensity conditioning in a large cohort of consecutive high-risk patients

A Rambaldi, A Bacigalupo, R Fanin, F Ciceri, F Bonifazi, M Falda, G Lambertenghi-Deliliers, F Benedetti, B Bruno, P Corradini, P E Alessandrino, P Iacopino, W Arcese, R Scimè, R Raimondi, S Sica, L Castagna, T Lamparelli, R Oneto, L Lombardini, S Pollichieni, A Algarotti, A Carobbio, N Sacchi and A Bosi on behalf of Gruppo Italiano Trapianto di Midollo Osseo, GITMO

Leukemia 2012 26: 1779-1785; advance online publication, March 1, 2012; 10.1038/leu.2012.55

Abstract | Full Text

ACUTE LEUKEMIAS

Treatment of acute lymphoblastic leukemia with an rGel/BLyS fusion toxin

R Parameswaran, M Yu, M-A Lyu, M Lim, M G Rosenblum, J Groffen and N Heisterkamp

Leukemia 2012 26: 1786-1796; advance online publication, February 29, 2012; 10.1038/leu.2012.54

Abstract | Full Text

CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia

A Inthal, P Zeitlhofer, M Zeginigg, M Morak, R Grausenburger, E Fronkova, B Fahrner, G Mann, O A Haas and R Panzer-Grümayer

Leukemia 2012 26: 1797-1803; advance online publication, March 5, 2012; 10.1038/leu.2012.60

Abstract | Full Text

MYELODYSPLASIAS

5-Azacitidine in aggressive myelodysplastic syndromes regulates chromatin structure at PU.1 gene and cell differentiation capacity

N Curik, P Burda, K Vargova, V Pospisil, M Belickova, P Vlckova, F Savvulidi, E Necas, H Hajkova, C Haskovec, J Cermak, M Krivjanska, M Trneny, P Laslo, A Jonasova and T Stopka

Leukemia 2012 26: 1804-1811; advance online publication, February 20, 2012; 10.1038/leu.2012.47

Abstract | Full Text

CHRONIC LYMPHOCYTIC LEUKEMIA

Stromal cells modulate TCL1 expression, interacting AP-1 components and TCL1-targeting micro-RNAs in chronic lymphocytic leukemia

M Sivina, E Hartmann, E Vasyutina, J M Boucas, A Breuer, M J Keating, W G Wierda, A Rosenwald, M Herling and J A Burger

Leukemia 2012 26: 1812-1820; advance online publication, March 5, 2012; 10.1038/leu.2012.63

Abstract | Full Text

The EuroChimerism concept for a standardized approach to chimerism analysis after allogeneic stem cell transplantation

T Lion, F Watzinger, S Preuner, H Kreyenberg, M Tilanus, R de Weger, J van Loon, L de Vries, H Cavé, C Acquaviva, M Lawler, M Crampe, A Serra, B Saglio, F Colnaghi, A Biondi, J J M van Dongen, M van der Burg, M Gonzalez, M Alcoceba, G Barbany, M Hermanson, E Roosnek, C Steward, J Harvey, F Frommlet and P Bader on behalf of the EuroChimerism Consortium (EU-Project number: QLG1-CT-2002-01485)

Leukemia 2012 26: 1821-1828; advance online publication, March 7, 2012; 10.1038/leu.2012.66

Abstract | Full Text

ONCOGENES, FUSION GENES AND TUMOR SUPPRESSOR GENES

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

A Ptasinska, S A Assi, D Mannari, S R James, D Williamson, J Dunne, M Hoogenkamp, M Wu, M Care, H McNeill, P Cauchy, M Cullen, R M Tooze, D G Tenen, B D Young, P N Cockerill, D R Westhead, O Heidenreich and C Bonifer

Leukemia 2012 26: 1829-1841; advance online publication, February 20, 2012; 10.1038/leu.2012.49

Abstract | Full Text

Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia

A Zebisch, A Wölfler, I Fried, O Wolf, K Lind, C Bodner, M Haller, A Drasche, D Pirkebner, D Matallanas, O Rath, K Blyth, R Delwel, E Taskesen, F Quehenberger, W Kolch, J Troppmair and H Sill

Leukemia 2012 26: 1842-1849; advance online publication, March 5, 2012; 10.1038/leu.2012.61

Abstract | Full Text

DIFFERENTIATION

p38αMAPK interacts with and inhibits RARα: suppression of the kinase enhances the therapeutic activity of retinoids in acute myeloid leukemia cells

M Gianni, M Peviani, N Bruck, A Rambaldi, G Borleri, M Terao, M Kurosaki, G Paroni, C Rochette-Egly and E Garattini

Leukemia 2012 26: 1850-1861; advance online publication, February 22, 2012; 10.1038/leu.2012.50

Abstract | Full Text

MYELOMA

Clinical significance of CD81 expression by clonal plasma cells in high-risk smoldering and symptomatic multiple myeloma patients

B Paiva, N-C Gutiérrez, X Chen, M-B Vídriales, M-Á Montalbán, L Rosiñol, A Oriol, J Martínez-López, M-V Mateos, L López-Corral, E Díaz-Rodríguez, J-J Pérez, E Fernández-Redondo, F de Arriba, L Palomera, E Bengoechea, M-J Terol, R de Paz, A Martin, J Hernández, A Orfao, J-J Lahuerta, J Bladé, A Pandiella and J-F San Miguel on behalf of the GEM (Grupo Español de Mieloma)/PETHEMA (Programa para el Estudio de la Terapéutica en Hemopatías Malignas) cooperative study groups

Leukemia 2012 26: 1862-1869; advance online publication, February 15, 2012; 10.1038/leu.2012.42

Abstract | Full Text

Curative one-shot systemic virotherapy in murine myeloma

S Naik, R Nace, M J Federspiel, G N Barber, K-W Peng and S J Russell

Leukemia 2012 26: 1870-1878; advance online publication, March 19, 2012; 10.1038/leu.2012.70

Abstract | Full Text

Letters to the Editor

Top

Novel splicing-factor mutations in juvenile myelomonocytic leukemia

J Takita, K Yoshida, M Sanada, R Nishimura, J Okubo, A Motomura, M Hiwatari, K Oki, T Igarashi, Y Hayashi and S Ogawa

Leukemia 2012 26: 1879-1881; advance online publication, February 20, 2012; 10.1038/leu.2012.45

Full Text

Sequencing histone-modifying enzymes identifies UTX mutations in acute lymphoblastic leukemia

B G Mar, L Bullinger, E Basu, K Schlis, L B Silverman, K Döhner and S A Armstrong

Leukemia 2012 26: 1881-1883; advance online publication, March 1, 2012; 10.1038/leu.2012.56

Full Text

Evaluating surface erythropoietin receptor in multiple myeloma

C P Miller, K Rattray, Y Zhang, B L Wood, N Burwick, S Chien, W I Bensinger, C A Blau and P S Becker

Leukemia 2012 26: 1883-1886; advance online publication, March 1, 2012; 10.1038/leu.2012.58

Full Text

A low thymic function is associated with leukemia relapse in children given T-cell-depleted HLA-haploidentical stem cell transplantation

E Clave, D Lisini, C Douay, G Giorgiani, M Busson, M Zecca, D Charron, M E Bernardo, A Toubert and F Locatelli

Leukemia 2012 26: 1886-1888; advance online publication, March 5, 2012; 10.1038/leu.2012.59

Full Text

Neoplastic B-cell growth is impaired by HLA-G/ILT2 interaction

A Naji, C Menier, G Maki, E D Carosella and N Rouas-Freiss

Leukemia 2012 26: 1889-1892; advance online publication, March 5, 2012; 10.1038/leu.2012.62

Full Text

SKLB1028, a novel oral multikinase inhibitor of EGFR, FLT3 and Abl, displays exceptional activity in models of FLT3-driven AML and considerable potency in models of CML harboring Abl mutants

Z-X Cao, J-J Liu, R-L Zheng, J Yang, L Zhong, Y Xu, L-J Wang, C-H Zhang, B-L Wang, S Ma, Z-R Wang, H-Z Xie, Y-Q Wei and S-Y Yang

Leukemia 2012 26: 1892-1895; advance online publication, March 9, 2012; 10.1038/leu.2012.67

Full Text

Non-nodal type of mantle cell lymphoma is a specific biological and clinical subgroup of the disease

C Royo, A Navarro, G Clot, I Salaverria, E Giné, P Jares, D Colomer, A Wiestner, W H Wilson, M C Vegliante, V Fernandez, E M Hartmann, N Trim, W N Erber, S H Swerdlow, W Klapper, M J S Dyer, M Vargas-Pabón, G Ott, A Rosenwald, R Siebert, A López-Guillermo, E Campo and S Beà

Leukemia 2012 26: 1895-1898; advance online publication, March 19, 2012; 10.1038/leu.2012.72

Full Text

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