Thursday, August 9, 2012

Gene Therapy - Table of Contents alert Volume 19 Issue 8

TABLE OF CONTENTS

Volume 19, Issue 8 (August 2012)

In this issue
Original Articles
Short Communication

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ARTICLE SPOTLIGHT

Antibodies against adeno-associated viral (AAV) vectors are highly prevalent in humans. In this article the authors provide insights into strategies to overcome the limitation of pre-existing humoral immunity to AAV vectors.

Prevalence and pharmacological modulation of humoral immunity to AAV vectors in gene transfer to synovial tissue Open
F Mingozzi and Colleagues
 
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Original Articles

Top

dsAAV8-mediated gene transfer and β-cell expression of IL-4 and β-cell growth factors are capable of reversing early-onset diabetes in NOD mice

D F Gaddy, M J Riedel, S Bertera, T J Kieffer and P D Robbins

Gene Ther 2012 19: 791-799; advance online publication, November 17, 2011; 10.1038/gt.2011.181

Abstract | Full Text

Novel random peptide libraries displayed on AAV serotype 9 for selection of endothelial cell-directed gene transfer vectors

K Varadi, S Michelfelder, T Korff, M Hecker, M Trepel, H A Katus, J A Kleinschmidt and O J Müller

Gene Ther 2012 19: 800-809; advance online publication, September 29, 2011; 10.1038/gt.2011.143

Abstract | Full Text

Artificial microRNA interference targeting AT1a receptors in paraventricular nucleus attenuates hypertension in rats

Z-D Fan, L Zhang, Z Shi, X-B Gan, X-Y Gao and G-Q Zhu

Gene Ther 2012 19: 810-817; advance online publication, September 29, 2011; 10.1038/gt.2011.145

Abstract | Full Text

Generating CTLs against the subdominant EBV LMP antigens by transient expression of an A20 inhibitor with EBV LMP proteins in human DCs

B Hong, G Peng, L Berry, S Gottschalk, J U Jung, S-Y Chen and X F Huang

Gene Ther 2012 19: 818-827; advance online publication, November 3, 2011; 10.1038/gt.2011.160

Abstract | Full Text

A designed curved DNA sequence remarkably enhances transgene expression from plasmid DNA in mouse liver

S Fukunaga, G Kanda, J Tanase, H Harashima, T Ohyama and H Kamiya

Gene Ther 2012 19: 828-835; advance online publication, September 15, 2011; 10.1038/gt.2011.127

Abstract | Full Text

Long-term effects of hepatocyte growth factor gene therapy in rat myocardial infarct model

Y-N Jin, M Inubushi, K Masamoto, K Odaka, I Aoki, A B Tsuji, M Sagara, M Koizumi and T Saga

Gene Ther 2012 19: 836-843; advance online publication, September 15, 2011; 10.1038/gt.2011.128

Abstract | Full Text

Development of the hybrid Sleeping Beauty-baculovirus vector for sustained gene expression and cancer therapy

W-Y Luo, Y-S Shih, C-L Hung, K-W Lo, C-S Chiang, W-H Lo, S-F Huang, S-C Wang, C-F Yu, C-H Chien and Y-C Hu

Gene Ther 2012 19: 844-851; advance online publication, September 15, 2011; 10.1038/gt.2011.129

Abstract | Full Text

Robust spinal motor neuron transduction following intrathecal delivery of AAV9 in pigs

T Federici, J S Taub, G R Baum, S J Gray, J C Grieger, K A Matthews, C R Handy, M A Passini, R J Samulski and N M Boulis

Gene Ther 2012 19: 852-859; advance online publication, September 15, 2011; 10.1038/gt.2011.130

Abstract | Full Text

Low-density lipoprotein receptor gene transfer in hypercholesterolemic mice improves cardiac function after myocardial infarction

E Van Craeyveld, F Jacobs, S C Gordts and B De Geest

Gene Ther 2012 19: 860-871; advance online publication, October 6, 2011; 10.1038/gt.2011.147

Abstract | Full Text

Short Communication

Top

Critical Variables affecting clinical-grade production of the self-inactivating gamma-retroviral vector for the treatment of X-linked severe combined immunodeficiency

J C M van der Loo, W P Swaney, E Grassman, A Terwilliger, T Higashimoto, A Schambach, S Hacein-Bey-Abina, D L Nordling, M Cavazzana-Calvo, A J Thrasher, D A Williams, L Reeves and P Malik

Gene Ther 2012 19: 872-876; advance online publication, May 3, 2012; 10.1038/gt.2012.37

Abstract | Full Text

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