| |  |  | | | | | Weekly Content Alert |  | | 24 July 2012 |  | | Featured image: |  |  |  | | Finnemore et al. synthesize iridescent and mechanically tough artificial nacre using a biomimetic approach. | | | | | |  | Advertisement |  | Nature Medicine and the Volkswagen Foundation present: Herrenhausen Symposium on Metastasis October 8-10, 2012 - Seeon, Germany A subset of leaders in the field will attend the Herrenhausen Symposium and participate in an interdisciplinary discussion that will point in the direction of solutions to the greatest challenges that the field of viral pathogenesis faces. Apply today! | |  | | | | | Latest Articles | View all Articles | | | |  | Patterning symmetry in the rational design of colloidal crystals OPEN |  | | Flavio Romano and Francesco Sciortino |  | | Patchy colloids are colloidal particles with chemically or physically patterned surfaces that result in complex interactions arising between them. By means of numerical simulations, Romano and Sciortino show that suitably tailored patches can induce the crystallization of patchy colloids into specific crystal structures. |  | | 24 Jul | Nat Commun 3:975 doi:10.1038/ncomms1968 (2012) |  | | Physical sciences Condensed matter |  | | Materials science Physical chemistry |  | Abstract | Full Text | PDF (749 kB) | Supplementary Information | 
 | Roles of icosahedral and crystal-like order in the hard spheres glass transition OPEN |  | | Mathieu Leocmach and Hajime Tanaka |  | | The dynamics and structure of the glass transition in liquids is still debated. Using particle-level confocal microscopy, Leocmach and Tanaka investigate supercooled colloidal liquids and distinguish different scenarios for glassy slow dynamics, suggesting that local ordering may only play a minor role. |  | | 24 Jul | Nat Commun 3:974 doi:10.1038/ncomms1974 (2012) |  | | Physical sciences Condensed matter |  | | Materials science |  | Abstract | Full Text | PDF (1,076 kB) | Supplementary Information | 
 | Gating of cyclic nucleotide-gated channels is voltage dependent |  | | Arin Marchesi, Monica Mazzolini and Vincent Torre |  | | Cyclic nucleotide-gated channels are apparently voltage insensitive despite having the S4-type voltage sensor. Marchesi et al. show that the gating of wild-type CNGA1 and native CNG channels is voltage-independent in the presence of Li+, Na+ and K+, but that it is voltage-dependent in the presence of Rb+, Cs+ and organic cations. |  | | 24 Jul | Nat Commun 3:973 doi:10.1038/ncomms1972 (2012) |  | | Biological sciences Biophysics |  | | Neuroscience |  | Abstract | Full Text | PDF (2,872 kB) | Supplementary Information | 
 | The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis OPEN |  | | Melissa J. Cudmore, Peter W. Hewett, Shakil Ahmad, Ke-Qing Wang, Meng Cai, Bahjat Al-Ani, Takeshi Fujisawa, Bin Ma, Samir Sissaoui, Wenda Ramma, Mark R. Miller, David E. Newby, Yuchun Gu, Bernhard Barleon, Herbert Weich and Asif Ahmed |  | | Vascular endothelial growth factor receptors (VEGFRs) assemble in dimers, the composition of which is thought to influence their function. Here, Cudmore et al. create a synthetic ligand that specifically activates VEGFR-1:VEGFR-2 heterodimers and explore their role in regulating endothelial cell function. |  | | 24 Jul | Nat Commun 3:972 doi:10.1038/ncomms1977 (2012) |  | | Biological sciences Cell biology |  | | Chemical biology |  | Abstract | Full Text | PDF (1,193 kB) | Supplementary Information | 
 | Ambient-stable tetragonal phase in silver nanostructures OPEN |  | | Yugang Sun, Yang Ren, Yuzi Liu, Jianguo Wen, John S. Okasinski and Dean J. Miller |  | | Crystallization of noble metal atoms usually leads to the thermodynamically stable face-centred cubic phase. Sun et al. show that internal strain in silver nanoparticles leads to lattice distortion and a stable body-centred tetragonal phase. |  | | 24 Jul | Nat Commun 3:971 doi:10.1038/ncomms1963 (2012) |  | | Chemical sciences Materials science |  | | Nanotechnology |  | Abstract | Full Text | PDF (1,415 kB) | Supplementary Information | 
 | Structural correlations in the generation of polaron pairs in low-bandgap polymers for photovoltaics OPEN |  | | Raphael Tautz, Enrico Da Como, Thomas Limmer, Jochen Feldmann, Hans-Joachim Egelhaaf, Elizabeth von Hauff, Vincent Lemaur, David Beljonne, Seyfullah Yilmaz, Ines Dumsch, Sybille Allard and Ullrich Scherf |  | | The electronic and optical properties of polymer semiconductors are largely dictated by their chemical structure. This study examines the nature of the photoexcited states generated in donor–acceptor polymers, and uncovers the dynamics of polaron pairs generation and recombination. |  | | 24 Jul | Nat Commun 3:970 doi:10.1038/ncomms1967 (2012) |  | | Physical sciences Condensed matter |  | | Materials science Physical chemistry |  | Abstract | Full Text | PDF (910 kB) | Supplementary Information | 
 | Plasmonic black gold by adiabatic nanofocusing and absorption of light in ultra-sharp convex grooves OPEN |  | | Thomas Søndergaard, Sergey M. Novikov, Tobias Holmgaard, René L. Eriksen, Jonas Beermann, Zhanghua Han, Kjeld Pedersen and Sergey I. Bozhevolnyi |  | | Plasmonic effects can turn reflective metals into strong absorbers, although this is usually realized within narrow wavelength ranges near resonances. Using arrays of ultra-sharp convex grooves, Søndergaard et al. show that nonresonant absorption can lead to effective broadband light absorption. |  | | 24 Jul | Nat Commun 3:969 doi:10.1038/ncomms1976 (2012) |  | | Physical sciences Optical physics |  | Abstract | Full Text | PDF (532 kB) | Supplementary Information | 
 | Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains |  | | Le Cong, Ruhong Zhou, Yu-chi Kuo, Margaret Cunniff and Feng Zhang |  | | The peptide sequence of transcription activator-like effectors (TALEs) can be customized to tailor the binding of TALEs to specific DNA sequences. Cong et al. improve TALE specificity for guanine binding and use a genetic construct based on TALEs to efficiently repress expression of a target gene. |  | | 24 Jul | Nat Commun 3:968 doi:10.1038/ncomms1962 (2012) |  | | Biological sciences Genetics |  | | Molecular biology |  | Abstract | Full Text | PDF (463 kB) | Supplementary Information | 
 | Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation OPEN |  | | Atsushi Saito, Soshi Kanemoto, Noritaka Kawasaki, Rie Asada, Hideo Iwamoto, Mami Oki, Hidetaka Miyagi, Soutarou Izumi, Tsukasa Sanosaka, Kinichi Nakashima and Kazunori Imaizumi |  | | The protein OASIS belongs to the CREB/ATF transcription factor family and is involved in endoplasmic reticulum stress responses. Saito and colleagues show that these stress responses temporally activate OASIS in neural precursor cells, resulting in their differentiation into astrocytes. |  | | 24 Jul | Nat Commun 3:967 doi:10.1038/ncomms1971 (2012) |  | | Biological sciences Neuroscience |  | Abstract | Full Text | PDF (1,780 kB) | Supplementary Information | 
 | Biomimetic layer-by-layer assembly of artificial nacre |  | | Alexander Finnemore, Pedro Cunha, Tamaryn Shean, Silvia Vignolini, Stefan Guldin, Michelle Oyen and Ullrich Steiner |  | | Nacre is an organic–inorganic composite biomaterial, which consists of an ordered multilayer structure of crystalline calcium carbonate platelets separated by porous organic layers. Finnemore et al. present a route to artificial nacre which mimics the natural layer-by-layer biosynthesis. |  | | 24 Jul | Nat Commun 3:966 doi:10.1038/ncomms1970 (2012) |  | | Physical sciences Materials science |  | Abstract | Full Text | PDF (716 kB) | Supplementary Information | 
 | Pronounced interannual variability in tropical South Pacific temperatures during Heinrich Stadial 1 OPEN |  | | Thomas Felis, Ute Merkel, Ryuji Asami, Pierre Deschamps, Ed C. Hathorne, Martin Kölling, Edouard Bard, Guy Cabioch, Nicolas Durand, Matthias Prange, Michael Schulz, Sri Yudawati Cahyarini and Miriam Pfeiffer |  | | During the last glacial termination, the North Atlantic experienced a cold interval, but its impact on tropical climate variability is not clear. Here, a fossil Tahiti coral record shows that tropical sea surface temperature varied actively during this event, consistent with climate model simulations. |  | | 24 Jul | Nat Commun 3:965 doi:10.1038/ncomms1973 (2012) |  | | Earth sciences Biogeochemistry |  | | Climate science Oceanography |  | | |  | Abstract | Full Text | PDF (651 kB) | Supplementary Information |  | | | | | | | |  |  |  |  |  |  | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here.
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