Scientific Reports Biology Table of Contents e-alert: May 2012

01 May 2012      • Visit Scientific Reports • Submit your manuscript to Scientific Reports     Welcome to your Table of Contents e-alert for Scientific Reports             Nature Reviews Cancer & Nature Reviews Immunology FOCUS ON TUMOUR IMMUNOLOGY & IMMUNOTHERAPY Access the Focus online for FREE until end of September 2012: www.nature.com/reviews/focus/tumourimmunology Produced with support from Boehringer Ingelheim               Biological Sciences               Engineering a thermo-stable superoxide dismutase functional at sub-zero to >50°C, which also tolerates autoclaving ▶     Arun Kumar, Som Dutt, Ganesh Bagler et al.     Superoxide dismutase (SOD) is a critical enzyme associated with controlling oxygen toxicity arising out of oxidative stress in any living system. A hyper-thermostable SOD isolated …             A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing ▶     Andrea Ferrante, Jack Gorski     The mechanism of HLA-DM (DM) activity is still unclear. We have shown that DM-mediated peptide release from HLA-DR (DR) is dependent on the presence of exchange peptide. However, …             From father to son: transgenerational effect of tetracycline on sperm viability ▶     Jeanne A. Zeh, Melvin M. Bonilla, Angelica J. Adrian et al.     The broad-spectrum antibiotic tetracycline is used in animal production, antimicrobial therapy, and for curing arthropods infected with bacterial endosymbionts such as Wolbachia. …             Oxytocin attenuates feelings of hostility depending on emotional context and individuals' characteristics ▶     Tetsu Hirosawa, Mitsuru Kikuchi, Haruhiro Higashida et al.     In humans, oxytocin (OT) enhances prosocial behaviour. However, it is still unclear how the prosocial effects of OT are modulated by emotional features and/or individuals' …             Presence of Amorphous Carbon Nanoparticles in Food Caramels ▶     Md Palashuddin Sk, Amit Jaiswal, Anumita Paul et al.     We report the finding of the presence of carbon nanoparticles (CNPs) in different carbohydrate based food caramels, viz. bread, jaggery, sugar caramel, corn flakes and biscuits, …             TRPA1 Contributes to the Acute Inflammatory Response and Mediates Carrageenan-Induced Paw Edema in the Mouse ▶     Lauri J. Moilanen, Mirka Laavola, Meiju Kukkonen et al.     Transient receptor potential ankyrin 1 (TRPA1) is an ion channel involved in thermosensation and nociception. TRPA1 is activated by exogenous irritants and also by oxidants formed …             Identification of 14-3-3γ as a Mieap-interacting protein and its role in mitochondrial quality control ▶     Takafumi Miyamoto, Noriaki Kitamura, Masaya Ono et al.     Mieap, a p53-inducible protein, controls mitochondrial integrity by inducing the accumulation of lysosomal proteins within mitochondria. This phenomenon is designated MALM, for M…             Intermittent exposure to traces of green leaf volatiles triggers a plant response ▶     Kaori Shiojiri, Rika Ozawa, Kenji Matsui et al.     Plants are known to mount a defensive response when exposed to volatile chemicals from other plants, but the critical concentration required for this response is not known. We …             Genomic analysis of Pseudomonas putida: genes in a genome island are crucial for nicotine degradation ▶     Hongzhi Tang, Yuxiang Yao, Lijuan Wang et al.     Nicotine is an important chemical compound in nature that has been regarded as an environmental toxicant causing various preventable diseases. Several bacterial species are …             Multiple tyrosine metabolites are GPR35 agonists ▶     Huayun Deng, Haibei Hu, Ye Fang     Both kynurenic acid and 2-acyl lysophosphatidic acid have been postulated to be the endogenous agonists of GPR35. However, controversy remains whether alternative endogenous …             Competing activation mechanisms in epidemics on networks ▶     Claudio Castellano, Romualdo Pastor-Satorras     In contrast to previous common wisdom that epidemic activity in heterogeneous networks is dominated by the hubs with the largest number of connections, recent research has pointed …             Sex differences in intimate relationships ▶     Vasyl Palchykov, Kimmo Kaski, Janos Kertész et al.     Social networks based on dyadic relationships are fundamentally important for understanding of human sociality. However, we have little understanding of the dynamics of close …             A high-throughput behavioral paradigm for Drosophila olfaction - The Flywalk ▶     Kathrin Steck, Daniel Veit, Ronald Grandy et al.     How can odor-guided behavior of numerous individual Drosophila be assessed automatically with high temporal resolution? For this purpose we introduce the automatic integrated …             Indiscriminable sounds determine the direction of visual motion ▶     Maori Kobayashi, Wataru Teramoto, Souta Hidaka et al.     On cross-modal interactions, top-down controls such as attention and explicit identification of cross-modal inputs were assumed to play crucial roles for the optimization. Here we …             Calcineurin Controls Voltage-Dependent-Inactivation (VDI) of the Normal and Timothy Cardiac Channels ▶     Moshe Cohen-Kutner, Yfat Yahalom, Michael Trus et al.     Ca2-entry in the heart is tightly controlled by Cav1.2 inactivation, which involves Ca2-dependent inactivation (CDI) and voltage-dependent inactivation (VDI) components. Timothy …             If players are sparse social dilemmas are too: Importance of percolation for evolution of cooperation ▶     Zhen Wang, Attila Szolnoki, Matjaž Perc     Spatial reciprocity is a well known tour de force of cooperation promotion. A thorough understanding of the effects of different population densities is therefore crucial. Here we …             High susceptibility to lipopolysaccharide-induced lethal shock in encephalomyocarditis virus-infected mice ▶     Hirofumi Ohtaki, Hiroyasu Ito, Masato Hoshi et al.     Secondary bacterial infection in humans is one of the pathological conditions requiring clinical attention. In this study, we examined the effect of lipopolysaccharide (LPS) on …             The eye limits the brain's learning potential ▶     Jiawei Zhou, Yudong Zhang, Yun Dai et al.     The concept of a critical period for visual development early in life during which sensory experience is essential to normal neural development is now well established. However …             Delivery of subunit influenza vaccine to skin with microneedles improves immunogenicity and long-lived protection ▶     Dimitrios G. Koutsonanos, Elena V. Vassilieva, Anastasia Stavropoulou et al.     Influenza infection represents a major socio-economic burden worldwide. Novel delivery methods can render influenza vaccination easier and more acceptable by the public, and …             Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells ▶     Chang W. Song, Hyemi Lee, Ruud P. M. Dings et al.     The anti-cancer effects of metformin, the most widely used drug for type 2 diabetes, alone or in combination with ionizing radiation were studied with MCF-7 human breast cancer …             Therapeutic potential of HIV protease-activable CASP3 ▶     Kosuke Miyauchi, Emiko Urano, Mari Takizawa et al.     Development of a therapeutic application of CASP3/caspase 3/CPP32, an executor of apoptosis, has been challenging because regulation of its activation is complicated. This study …             Single cell genome analysis supports a link between phagotrophy and primary plastid endosymbiosis ▶     Debashish Bhattacharya, Dana C. Price, Hwan Su Yoon et al.     Two cases of primary plastid endosymbiosis are known. The first occurred ca. 1.6 billion years ago and putatively gave rise to the canonical plastid in algae and plants. The …             Paleolithic Contingent in Modern Japanese: Estimation and Inference using Genome-wide Data ▶     Yungang He, Wei R. Wang, Shuhua Xu et al.     The genetic origins of Japanese populations have been controversial. Upper Paleolithic Japanese, i.e. Jomon, developed independently in Japanese islands for more than 10,000 years …             Amylases without known homologues discovered in an acid mine drainage: significance and impact ▶     François Delavat, Vincent Phalip, Anne Forster et al.     Acid Mine Drainages (AMDs) are extreme environments characterized by acidic and oligotrophic conditions and by metal contaminations. A function-based screening of an AMD-derived …             Epstein-Barr virus latent membrane protein 2A exacerbates experimental autoimmune encephalomyelitis and enhances antigen presentation function ▶     Rhoda A. Chang, Stephen D. Miller, Richard Longnecker     Multiple sclerosis (MS) is an inflammatory, autoimmune disease of the central nervous system. The cause of MS is still unknown but epidemiological and immunological studies have …             A simple and efficient statistical potential for scoring ensembles of protein structures ▶     Pilar Cossio, Daniele Granata, Alessandro Laio et al.     In protein structure prediction it is essential to score quickly and reliably large sets of models by selecting the ones that are closest to the native state. We here present a …             STING Mediates Neuronal Innate Immune Response Following Japanese Encephalitis Virus Infection ▶     Arshed Nazmi, Rupanjan Mukhopadhyay, Kallol Dutta et al.     Flavivirus-mediated inflammation causes neuronal death, but whether the infected neurons can evoke an innate immune response to elicit their own protection, is unknown. In an …                         Scientific Reports is accepting submissions from all scientific fields. 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