Molecular Systems Biology - New articles published 22 May 2012

Latest Articles 22nd May 2012   Featured Article Research Article Report   Web feeds About Open access Featured Article Comparative transcriptomics of pathogenic and non-pathogenic Listeria species Comparative RNA-seq analysis of two related pathogenic and non-pathogenic bacterial strains reveals a hidden layer of divergence in the non-coding genome as well as conserved, widespread regulatory structures called ‘Excludons’, which mediate regulation through long non-coding antisense RNAs. Omri Wurtzel, Nina Sesto, J R Mellin, Iris Karunker, Sarit Edelheit, Christophe Bécavin, Cristel Archambaud, Pascale Cossart & Rotem Sorek Molecular Systems Biology 8:583; doi:10.1038/msb.2012.11; published 22 May 2012 Full Text | PDF | Supp. Inf. | Review Process Research Article Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response Live-cell imaging and mathematical modelling of the type-I interferon response to viral infection reveal that multiple layers of the cellular response are stochastic events in individual cells, while paracrine propagation of the IFN signal results in reliable antiviral protection. Ulfert Rand, Melanie Rinas, Johannes Schwerk, Gesa Nöhren, Melanie Linnes, Andrea Kröger, Michael Flossdorf, Kristóf Kály-Kullai, Hansjörg Hauser, Thomas Höfer & Mario Köster Molecular Systems Biology 8:584; doi:10.1038/msb.2012.17; published 22 May 2012 Full Text | PDF | Supp. Inf. | Review Process Report Transcription start site associated RNAs in bacteria A new class of small RNA (~45 bases long) is identified in gram positive and negative bacteria. These tssRNAs are associated with RNA polymerase pausing some 45 bases downstream of the transcription start site and show global changes in expression during the growth cycle. Eva Yus, Marc Güell, Ana P Vivancos, Wei-Hua Chen, María Lluch-Senar, Javier Delgado, Anne Claude Gavin, Peer Bork & Luis Serrano Molecular Systems Biology 8:585; doi:10.1038/msb.2012.16; published 22 May 2012 Full Text | PDF | Supp. Inf. | Review Process

Advertisement

Follow EMBO on Facebook for access to news, comments and articles and make it a place to share information with others interested in the field. https://www.facebook.com/EMBO.excellence.in.life.sciences

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. For other enquiries, please contact our customer feedback department. Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2012 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.