Molecular Therapy - Table of Contents alert Volume 20 Issue 4

TABLE OF CONTENTS Volume 20, Issue 4 (April 2012) In this issue Editorial In This Issue Research Highlights Letters to the Editor Commentary Review Original Articles Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement Pediatric Research Reviews Highlights Cell-based therapies in 2012 Published in April 2012 as a special supplemental issue of Pediatric Research, the annual review issue highlights cell-based therapies in pediatrics. The articles in this issue examine developments in cell-based therapies used for treating neonatal/pediatric neuronal damage, hematologic diseases, chronic inflammatory diseases and cancers. Visit www.nature.com/pr and gain access to these articles before they are published in print.   Editorial Top Seeing Eye to Eye With Gene Therapy Roland W Herzog Mol Ther 2012 20: 687-688; 10.1038/mt.2012.43 Full Text In This Issue Top In This Issue Mol Ther 2012 20: 690; 10.1038/mt.2012.54 Full Text Research Highlights Top Research Highlights Mol Ther 2012 20: 691; 10.1038/mt.2012.55 Full Text Letters to the Editor Top A Water-Soluble Coelenterazine for Sensitive In Vivo Imaging of Coelenterate Luciferases Danielle Morse and Bakhos A Tannous Mol Ther 2012 20: 692-693; 10.1038/mt.2012.38 Full Text Commentary Top mRNA Leapfrogs DNA to Show Promise for Therapeutic Gene Transfer Eli Gilboa Mol Ther 2012 20: 694-695; 10.1038/mt.2012.31 Full Text Do Cell-Penetrating Peptides Actually “Penetrate” Cellular Membranes? Caroline Palm-Apergi, Peter Lönn and Steven F Dowdy Mol Ther 2012 20: 695-697; 10.1038/mt.2012.40 Full Text Progress in the Development of Hepatitis C Virus Vaccines Hildegund CJ Ertl Mol Ther 2012 20: 697-698; 10.1038/mt.2012.30 Full Text Review Top The AAV Vector Toolkit: Poised at the Clinical Crossroads Aravind Asokan, David V Schaffer and R Jude Samulski Mol Ther 2012 20: 699-708; advance online publication, January 24, 2012; 10.1038/mt.2011.287 Abstract | Full Text Retroviral Integrations in Gene Therapy Trials Luca Biasco, Cristina Baricordi and Alessandro Aiuti Mol Ther 2012 20: 709-716; advance online publication, January 17, 2012; 10.1038/mt.2011.289 Abstract | Full Text Original Articles Top Co-administration With the Pharmacological Chaperone AT1001 Increases Recombinant Human α-Galactosidase A Tissue Uptake and Improves Substrate Reduction in Fabry Mice Elfrida R Benjamin, Richie Khanna, Adriane Schilling, John J Flanagan, Lee J Pellegrino, Nastry Brignol, Yi Lun, Darlene Guillen, Brian E Ranes, Michelle Frascella, Rebecca Soska, Jessie Feng, Leo Dungan, Brandy Young, David J Lockhart and Kenneth J Valenzano Mol Ther 2012 20: 717-726; advance online publication, January 3, 2012; 10.1038/mt.2011.271 Abstract | Full Text Enhancing Muscle Membrane Repair by Gene Delivery of MG53 Ameliorates Muscular Dystrophy and Heart Failure in δ-Sarcoglycan-deficient Hamsters Bo He, Ru-hang Tang, Noah Weisleder, Bin Xiao, Zhenhua Yuan, Chuanxi Cai, Hua Zhu, Peihui Lin, Chunping Qiao, Jianbin Li, Christina Mayer, Juan Li, Jianjie Ma and Xiao Xiao Mol Ther 2012 20: 727-735; advance online publication, February 7, 2012; 10.1038/mt.2012.5 Abstract | Full Text Treating Tumors With a Vaccinia Virus Expressing IFNβ Illustrates the Complex Relationships Between Oncolytic Ability and Immunogenicity Liang-Chuan S Wang, Rachel C Lynn, Guanjun Cheng, Edward Alexander, Veena Kapoor, Edmund K Moon, Jing Sun, Zvi G Fridlender, Stuart N Isaacs, Stephen H Thorne and Steven M Albelda Mol Ther 2012 20: 736-748; advance online publication, October 18, 2011; 10.1038/mt.2011.228 Abstract | Full Text The Oncolytic Poxvirus JX-594 Selectively Replicates in and Destroys Cancer Cells Driven by Genetic Pathways Commonly Activated in Cancers Kelley A Parato, Caroline J Breitbach, Fabrice Le Boeuf, Jiahu Wang, Chris Storbeck, Carolina Ilkow, Jean-Simon Diallo, Theresa Falls, Joseph Burns, Vanessa Garcia, Femina Kanji, Laura Evgin, Kang Hu, Francois Paradis, Shane Knowles, Tae-Ho Hwang, Barbara C Vanderhyden, Rebecca Auer, David H Kirn and John C Bell Mol Ther 2012 20: 749-758; advance online publication, December 20, 2011; 10.1038/mt.2011.276 Abstract | Full Text Myxoma Virus Sensitizes Cancer Cells to Gemcitabine and Is an Effective Oncolytic Virotherapeutic in Models of Disseminated Pancreatic Cancer Sonia Tusell Wennier, Jia Liu, Shoudong Li, Masmudur M. Rahman, Mahmoud Mona and Grant McFadden Mol Ther 2012 20: 759-768; advance online publication, January 10, 2012; 10.1038/mt.2011.293 Abstract | Full Text BioKnife, a uPA Activity-dependent Oncolytic Sendai Virus, Eliminates Pleural Spread of Malignant Mesothelioma via Simultaneous Stimulation of uPA Expression Yosuke Morodomi, Tokujiro Yano, Hiroaki Kinoh, Yui Harada, Satoru Saito, Ryoichi Kyuragi, Kumi Yoshida, Mitsuho Onimaru, Fumihiro Shoji, Tsukihisa Yoshida, Kensaku Ito, Yasunori Shikada, Riichiroh Maruyama, Mamoru Hasegawa, Yoshihiko Maehara and Yoshikazu Yonemitsu Mol Ther 2012 20: 769-777; advance online publication, February 7, 2012; 10.1038/mt.2011.305 Abstract | Full Text Adenovirus-mediated E2-EPF UCP Gene Transfer Prevents Autoamputation in a Mouse Model of Hindlimb Ischemia Jung Hwa Lim, Hyo Jung Shin, Kyeong-Su Park, Chan Hee Lee, Cho-Rok Jung and Dong-Soo Im Mol Ther 2012 20: 778-787; advance online publication, January 31, 2012; 10.1038/mt.2011.302 Abstract | Full Text Stanniocalcin-1 Rescued Photoreceptor Degeneration in Two Rat Models of Inherited Retinal Degeneration Gavin W Roddy, Robert H Rosa Jr, Joo Youn Oh, Joni H Ylostalo, Thomas J Bartosh, Jr, Hosoon Choi, Ryang Hwa Lee, Douglas Yasumura, Kelly Ahern, Gregory Nielsen, Michael T Matthes, Matthew M LaVail and Darwin J Prockop Mol Ther 2012 20: 788-797; advance online publication, January 31, 2012; 10.1038/mt.2011.308 Abstract | Full Text Preclinical Corrective Gene Transfer in Xeroderma Pigmentosum Human Skin Stem Cells Emilie Warrick, Marta Garcia, Corinne Chagnoleau, Odile Chevallier, Valérie Bergoglio, Daniela Sartori, Fulvio Mavilio, Jaime F Angulo, Marie-Françoise Avril, Alain Sarasin, Fernando Larcher, Marcela Del Rio, Françoise Bernerd and Thierry Magnaldo Mol Ther 2012 20: 798-807; advance online publication, November 8, 2011; 10.1038/mt.2011.233 Abstract | Full Text Immune-mediated Loss of Transgene Expression From Virally Transduced Brain Cells Is Irreversible, Mediated by IFNγ, Perforin, and TNFα, and due to the Elimination of Transduced Cells Jeffrey M Zirger, Mariana Puntel, Josee Bergeron, Mia Wibowo, Rameen Moridzadeh, Niyati Bondale, Carlos Barcia, Kurt M Kroeger, Chunyan Liu, Maria G Castro and Pedro R Lowenstein Mol Ther 2012 20: 808-819; advance online publication, January 10, 2012; 10.1038/mt.2011.243 Abstract | Full Text SHAPE-directed Discovery of Potent shRNA Inhibitors of HIV-1 Justin T Low, Stefanie A Knoepfel, Joseph M Watts, Olivier ter Brake, Ben Berkhout and Kevin M Weeks Mol Ther 2012 20: 820-828; advance online publication, February 7, 2012; 10.1038/mt.2011.299 Abstract | Full Text Intranasal Delivery of HMGB1 siRNA Confers Target Gene Knockdown and Robust Neuroprotection in the Postischemic Brain Il-Doo Kim, Joo-Hyun Shin, Seung-Woo Kim, Sunghyun Choi, Junseong Ahn, Pyung-Lim Han, Jong-Sang Park and Ja-Kyeong Lee Mol Ther 2012 20: 829-839; advance online publication, January 17, 2012; 10.1038/mt.2011.291 Abstract | Full Text HIV Develops Indirect Cross-resistance to Combinatorial RNAi Targeting Two Distinct and Spatially Distant Sites Priya S Shah, Nhung P Pham and David V Schaffer Mol Ther 2012 20: 840-848; advance online publication, January 31, 2012; 10.1038/mt.2012.3 Abstract | Full Text Zinc-finger Nuclease Editing of Human cxcr4 Promotes HIV-1 CD4+ T Cell Resistance and Enrichment Jinyun Yuan, Jianbin Wang, Karen Crain, Colleen Fearns, Kenneth A Kim, Kevin L Hua, Philip D Gregory, Michael C Holmes and Bruce E Torbett Mol Ther 2012 20: 849-859; advance online publication, January 24, 2012; 10.1038/mt.2011.310 Abstract | Full Text Combined mTOR Inhibition and OX40 Agonism Enhances CD8+ T Cell Memory and Protective Immunity Produced by Recombinant Adenovirus Vaccines Jennifer D Bassett, Stephanie L Swift, Heather VanSeggelen, Joanne A Hammill, AJ Robert McGray, Carole Evelegh, Yonghong Wan and Jonathan L Bramson Mol Ther 2012 20: 860-869; advance online publication, December 20, 2011; 10.1038/mt.2011.281 Abstract | Full Text Phase I Clinical Trial of Smad7 Knockdown Using Antisense Oligonucleotide in Patients With Active Crohn's Disease Giovanni Monteleone, Massimo C Fantini, Sara Onali, Francesca Zorzi, Giulia Sancesario, Sergio Bernardini, Emma Calabrese, Francesca Viti, Ivan Monteleone, Livia Biancone and Francesco Pallone Mol Ther 2012 20: 870-876; advance online publication, January 17, 2012; 10.1038/mt.2011.290 Abstract | Full Text American Society for Gene and Cell Therapy - Call for Abstracts The American Society for Gene and Cell Therapy will be accepting late abstract submissions for their upcoming 15th Annual Meeting to be held from May 16 - 19, 2012 in Philadelphia, PA; beginning March 1, 2012, with a deadline of April 2, 2012.   Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Molecular Therapy. 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