Wednesday, March 28, 2012

Molecular Systems Biology - New articles published 27 March 2012

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Featured Article

A regulatory role for repeated decoy transcription factor binding sites in target gene expression

Repetitive stretches of DNA that contain transcription factor (TF) binding sites can act as decoys that sequester TFs. This study shows that these decoy sites can have important indirect effects on transcriptional regulation by altering the dose–response between a TF and its target promoter.

Tek-Hyung Lee & Narendra Maheshri

Molecular Systems Biology 8:576; doi:10.1038/msb.2012.7; published 27 March 2012

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Editorial

Towards an ‘Oceans Systems Biology’

Eric Karsenti

Molecular Systems Biology 8:575; doi:10.1038/msb.2012.8; published 27 March 2012

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