Molecular Systems Biology - New articles published 13 March 2012

Latest Articles 13th March 2012   Featured Article Research Article   Web feeds About Open access Advertisement ACCELERATE YOUR RESEARCH: Save time & money for your project with our services to: - DISCOVER novel protein interactions; - VALIDATE protein functions in cell; - INHIBIT protein interactions with small molecules. Benefit from our expertise in protein interactions and get high-quality results. Over 200 publications in top-ranking journals and 900 researchers who trusted us. http://www.hybrigenics-services.com +33 (0)1 58 10 38 29   Featured Article The clock gene circuit in Arabidopsis includes a repressilator with additional feedback loops Recent findings are incorporated into a new mathematical model of the plant circadian clock, revealing a complex circuit structure comprised of multiple negative feedback loops, and predicting a repressive role for a key regulator, TOC1, which the authors confirm experimentally. Alexandra Pokhilko, Aurora Piñas Fernández, Kieron D Edwards, Megan M Southern, Karen J Halliday & Andrew J Millar Molecular Systems Biology 8:574; doi:10.1038/msb.2012.6; published 6 March 2012 Synopsis | Full Text | PDF | Supp. Inf. | Review Process Research Article Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry Proteomic analysis of T cells emerging from quiescence identifies dynamic network-level changes in key cellular processes. Disruption of two such processes, ribosome biogenesis and RNA splicing, reveals that the programs controlling cell growth and cell-cycle entry are separable. Stephen J Orr, Daniel R Boutz, Rong Wang, Constantinos Chronis, Nicholas C Lea, Thivyan Thayaparan, Emma Hamilton, Hanna Milewicz, Eric Blanc, Ghulam J Mufti, Edward M Marcotte & N Shaun B Thomas Molecular Systems Biology 8:573; doi:10.1038/msb.2012.5; published 13 March 2012 Full Text | PDF | Supp. Inf. | Review Process

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