TABLE OF CONTENTS
|  |  |  | Volume 26, Issue 3 (March 2012) |  | In this issue
Leading Article
How to Manage…
Spotlight Reviews
Reviews
Original Articles
Letters to the Editor
Also new
   AOP
| |  |  |  | | Advertisement |  | |  | | | Leading Article | Top |  | Azacitidine for treatment of imminent relapse in MDS or AML patients after allogeneic HSCT: results of the RELAZA trialU Platzbecker, M Wermke, J Radke, U Oelschlaegel, F Seltmann, A Kiani, I-M Klut, H Knoth, C Röllig, J Schetelig, B Mohr, X Graehlert, G Ehninger, M Bornhäuser and C Thiede Leukemia 2012 26: 381-389; advance online publication, September 2, 2011; 10.1038/leu.2011.234 Abstract | Full Text |  | How to Manage… | Top |  | How to manage lower-risk myelodysplastic syndromesM A Sekeres Leukemia 2012 26: 390-394; advance online publication, September 9, 2011; 10.1038/leu.2011.223 Abstract | Full Text |  | Spotlight Reviews | Top |  | SPOTLIGHT ON MIRNA AND HEMATOPOIESIS
| Epigenetic regulation of miRNA genes in acute leukemiaX Agirre, J Á Martínez-Climent, M D Odero and F Prósper Leukemia 2012 26: 395-403; advance online publication, December 6, 2011; 10.1038/leu.2011.344 Abstract | Full Text |  |  |  | MicroRNAs in inflammation and immune responsesJ Contreras and D S Rao Leukemia 2012 26: 404-413; advance online publication, December 20, 2011; 10.1038/leu.2011.356 Abstract | Full Text |  |  |  | SPOTLIGHT ON SIGNALING PATHWAYS REGULATING HSC
| Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentT C Luis, M Ichii, M H Brugman, P Kincade and F J T Staal Leukemia 2012 26: 414-421; advance online publication, December 15, 2011; 10.1038/leu.2011.387 Abstract | Full Text |  | Reviews | Top |  | Commentary: does immune suppression increase risk of developing acute myeloid leukemia?R P Gale and G Opelz Leukemia 2012 26: 422-423; advance online publication, August 26, 2011; 10.1038/leu.2011.224 Abstract | Full Text |  |  |  | Regulatory T cells and immunodeficiency in mycosis fungoides and Sézary syndromeT Krejsgaard, N Odum, C Geisler, M A Wasik and A Woetmann Leukemia 2012 26: 424-432; advance online publication, September 9, 2011; 10.1038/leu.2011.237 Abstract | Full Text |  |  |  | Impact of arsenic trioxide in the treatment of acute promyelocytic leukemiaE Lengfelder, W-K Hofmann and D Nowak Leukemia 2012 26: 433-442; advance online publication, September 9, 2011; 10.1038/leu.2011.245 Abstract | Full Text |  | Original Articles | Top |  | ACUTE LEUKEMIAS
| MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AMLB Z Carter, D H Mak, Y Shi, J M Fidler, R Chen, X Ling, W Plunkett and M Andreeff Leukemia 2012 26: 443-450; advance online publication, September 9, 2011; 10.1038/leu.2011.246 Abstract | Full Text |  |  |  | (+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivoG A S dos Santos, R S Abreu e Lima, C R Pestana, A S G Lima, P S Scheucher, C H Thomé, H L Gimenes-Teixeira, B A A Santana-Lemos, A R Lucena-Araujo, F P Rodrigues, R Nasr, S A Uyemura, R P Falcão, H de Thé, P P Pandolfi, C Curti and E M Rego Leukemia 2012 26: 451-460; advance online publication, August 26, 2011; 10.1038/leu.2011.216 Abstract | Full Text |  |  |  | Allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia with t(6;9)(p23;q34) dramatically improves the patient prognosis: a matched-pair analysisK Ishiyama, A Takami, Y Kanda, S Nakao, M Hidaka, T Maeda, T Naoe, S Taniguchi, K Kawa, T Nagamura, Y Atsuta and H Sakamaki Leukemia 2012 26: 461-464; advance online publication, August 26, 2011; 10.1038/leu.2011.229 Abstract | Full Text |  |  |  | CHRONIC MYELOPROLIFERATIVE NEOPLASIAS
| NK cells are dysfunctional in human chronic myelogenous leukemia before and on imatinib treatment and in BCR–ABL-positive miceC I-U Chen, S Koschmieder, L Kerstiens, M Schemionek, B Altvater, S Pscherer, J Gerss, H T Maecker, W E Berdel, H Juergens, P P Lee and C Rossig Leukemia 2012 26: 465-474; advance online publication, September 9, 2011; 10.1038/leu.2011.239 Abstract | Full Text |  |  |  | IDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617FA Tefferi, T Jimma, N H Sulai, T L Lasho, C M Finke, R A Knudson, R F McClure and A Pardanani Leukemia 2012 26: 475-480; advance online publication, September 13, 2011; 10.1038/leu.2011.253 Abstract | Full Text |  |  |  | The JAK2V617F oncogene requires expression of inducible phosphofructokinase/fructose-bisphosphatase 3 for cell growth and increased metabolic activityM M Reddy, M S Fernandes, A Deshpande, E Weisberg, H V Inguilizian, O Abdel-Wahab, A L Kung, R L Levine, J D Griffin and M Sattler Leukemia 2012 26: 481-489; advance online publication, August 23, 2011; 10.1038/leu.2011.225 Abstract | Full Text |  |  |  | Release of intracellular calcium primes chronic myeloid leukaemia cells for tyrosine kinase inhibitor-induced apoptosisS L Forchap, M Pirmohamed and R E Clark Leukemia 2012 26: 490-498; advance online publication, September 2, 2011; 10.1038/leu.2011.231 Abstract | Full Text |  |  |  | CHRONIC LYMPHOCYTIC LEUKEMIA
| Proliferation centers in chronic lymphocytic leukemia: correlation with cytogenetic and clinicobiological features in consecutive patients analyzed on tissue microarraysM Ciccone, C Agostinelli, G M Rigolin, P P Piccaluga, F Cavazzini, S Righi, M T Sista, O Sofritti, L Rizzotto, E Sabattini, G Fioritoni, S Falorio, C Stelitano, A Olivieri, I Attolico, M Brugiatelli, P L Zinzani, E Saccenti, D Capello, M Negrini, A Cuneo and S Pileri Leukemia 2012 26: 499-508; advance online publication, September 23, 2011; 10.1038/leu.2011.247 Abstract | Full Text |  |  |  | STEM CELLS
| Early recipient chimerism testing in the T- and NK-cell lineages for risk assessment of graft rejection in pediatric patients undergoing allogeneic stem cell transplantationS Breuer, S Preuner, G Fritsch, H Daxberger, M Koenig, U Poetschger, A Lawitschka, C Peters, G Mann, T Lion and S Matthes-Martin Leukemia 2012 26: 509-519; advance online publication, September 16, 2011; 10.1038/leu.2011.244 Abstract | Full Text |  |  |  | LYMPHOMA
| Allogeneic transplantation following a reduced-intensity conditioning regimen in relapsed/refractory peripheral T-cell lymphomas: long-term remissions and response to donor lymphocyte infusions support the role of a graft-versus-lymphoma effectA Dodero, F Spina, F Narni, F Patriarca, I Cavattoni, F Benedetti, F Ciceri, D Baronciani, R Scimè, E Pogliani, A Rambaldi, F Bonifazi, S Dalto, B Bruno and P Corradini Leukemia 2012 26: 520-526; advance online publication, September 9, 2011; 10.1038/leu.2011.240 Abstract | Full Text |  | Letters to the Editor | Top |  | Persistence of mutant isocitrate dehydrogenase in patients with acute myeloid leukemia in remissionW-C Chou, K-Y Peng, W-C Lei, B-S Ko, W Tsay, C-H Kuo and H-F Tien Leukemia 2012 26: 527-529; advance online publication, August 16, 2011; 10.1038/leu.2011.215 Full Text |  |  |  | WT1 peptide vaccination following allogeneic stem cell transplantation in pediatric leukemic patients with high risk for relapse: successful maintenance of durable remissionY Hashii, E Sato-Miyashita, R Matsumura, S Kusuki, H Yoshida, H Ohta, N Hosen, A Tsuboi, Y Oji, Y Oka, H Sugiyama and K Ozono Leukemia 2012 26: 530-532; advance online publication, August 26, 2011; 10.1038/leu.2011.226 Full Text |  |  |  | Functional role of BAALC in leukemogenesisM Heuser, T Berg, F Kuchenbauer, C K Lai, G Park, S Fung, G Lin, M Leung, J Krauter, A Ganser and R K Humphries Leukemia 2012 26: 532-536; advance online publication, August 26, 2011; 10.1038/leu.2011.228 Full Text |  |  |  | NIH-defined graft-versus-host disease after reduced intensity or myeloablative conditioning in patients with acute myeloid leukemiaT H Terwey, A Vega-Ruiz, P G Hemmati, P Martus, E Dietz, P le Coutre, G Massenkeil, B Dörken and R Arnold Leukemia 2012 26: 536-542; advance online publication, August 26, 2011; 10.1038/leu.2011.230 Full Text |  |  |  | SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblastsV Visconte, H Makishima, A Jankowska, H Szpurka, F Traina, A Jerez, C O'Keefe, H J Rogers, M A Sekeres, J P Maciejewski and R V Tiu Leukemia 2012 26: 542-545; advance online publication, September 2, 2011; 10.1038/leu.2011.232 Full Text |  |  |  | Action of novel CD37 antibodies on chronic lymphocytic leukemia cellsG Krause, M Patz, P Isaeva, M Wigger, I Baki, V Vondey, S Kerwien, M Kuckertz, R Brinker, J Claasen, L P Frenzel, C-M Wendtner, K-H Heider and M Hallek Leukemia 2012 26: 546-549; advance online publication, September 2, 2011; 10.1038/leu.2011.233 Full Text |  |  |  | Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalitiesC Vicente, I Vazquez, A Conchillo, M A García-Sánchez, N Marcotegui, O Fuster, M González, M J Calasanz, I Lahortiga and M D Odero Leukemia 2012 26: 550-554; advance online publication, September 9, 2011; 10.1038/leu.2011.235 Full Text |  |  |  | The NPM1 wild-type OCI-AML2 and the NPM1-mutated OCI-AML3 cell lines carry DNMT3A mutationsE Tiacci, A Spanhol-Rosseto, M P Martelli, L Pasqualucci, H Quentmeier, V Grossmann, H G Drexler and B Falini Leukemia 2012 26: 554-557; advance online publication, September 9, 2011; 10.1038/leu.2011.238 Full Text |  |  |  | The surface molecule signature of primary human acute myeloid leukemia (AML) cells is highly associated with NPM1 mutation statusG Tsykunova, H Reikvam, R Hovland and Ø Bruserud Leukemia 2012 26: 557-559; advance online publication, September 9, 2011; 10.1038/leu.2011.243 Full Text |  |  |  | High rate of TNFRSF14 gene alterations related to 1p36 region in de novo follicular lymphoma and impact on prognosisE Launay, C Pangault, P Bertrand, F Jardin, T Lamy, H Tilly, K Tarte, C Bastard and T Fest Leukemia 2012 26: 559-562; advance online publication, September 23, 2011; 10.1038/leu.2011.266 Full Text |  |  |  |  |  | | Advertisement |  | |
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