Autoimmune Disease: Clinical Translation of Basic Immunology |
|  | Autoimmunity occurs when an organism develops an immune response against itself, resulting in an inflammatory reaction which damages organs such as brain, joints or pancreas. This results in diseases such as Type 1 diabetes, vasculitis, or rheumatoid arthritis. A fine balance exists in order to accommodate the control of microbial pathogens and commensals, and immune self-tolerance. The March 2012 issue will include a review series on Autoimmune Disease, particularly featuring articles on clinical translation, and the current state of research in this area. Articles include reasons for the increased incidence of certain autoimmune diseases and allergic diseases in Western society and the advances made by the application of novel and high throughput technologies to the analysis of diseased tissues. The accompanying web focus presents links to related articles from across Nature Publishing Group. |  | TABLE OF CONTENTS
|  |  |  | Volume 90, Issue 3 (March 2012) |  | In this issue News and Commentary Editorial Reviews Theoretical Article Original Articles
Also new    AOP
| |  |  |  | | Advertisement |  | |  | | | News and Commentary | Top |  | Graft-versus-host disease: who's responsible?Rhodri Ceredig Immunol Cell Biol 2011 90: 253-254; advance online publication, July 12, 2011; 10.1038/icb.2011.62 Full Text |  | Editorial | Top |  | Autoimmunity: innovation in pathogenesis and therapyRanjeny Thomas Immunol Cell Biol 2012 90: 255; 10.1038/icb.2012.5 Full Text | PDF |  | Reviews | Top |  | Regulatory T-cell abnormalities and the global epidemic of immuno-inflammatory diseaseBarbara Fazekas de St Groth Immunol Cell Biol 2012 90: 256-259; advance online publication, February 7, 2012; 10.1038/icb.2011.113 Abstract | Full Text |  |  |  | The interplay between endoplasmic reticulum stress and inflammationSumaira Z Hasnain, Rohan Lourie, Indrajit Das, Alice C-H Chen and Michael A McGuckin Immunol Cell Biol 2012 90: 260-270; advance online publication, January 17, 2012; 10.1038/icb.2011.112 Abstract | Full Text |  |  |  | Is the origin of type 1 diabetes in the gut?Outi Vaarala Immunol Cell Biol 2012 90: 271-276; advance online publication, January 31, 2012; 10.1038/icb.2011.115 Abstract | Full Text |  |  |  | T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and manShimon Sakaguchi, Helen Benham, Andrew P Cope and Ranjeny Thomas Immunol Cell Biol 2012 90: 277-287; 10.1038/icb.2012.4 Abstract | Full Text |  |  |  | Novel regulatory mechanisms in inflammatory arthritis: a role for microRNADerek Baxter, Iain B McInnes and Mariola Kurowska-Stolarska Immunol Cell Biol 2012 90: 288-292; advance online publication, January 17, 2012; 10.1038/icb.2011.114 Abstract | Full Text |  |  |  | BAFF and innate immunity: new therapeutic targets for systemic lupus erythematosusFabien B Vincent, Eric F Morand and Fabienne Mackay Immunol Cell Biol 2012 90: 293-303; advance online publication, January 10, 2012; 10.1038/icb.2011.111 Abstract | Full Text |  |  |  | Pathogenicity and proteomic signatures of autoantibodies to Ro and LaRhianna Lindop, Georgia Arentz, Lauren A Thurgood, Joanne H Reed, Michael W Jackson and Tom P Gordon Immunol Cell Biol 2012 90: 304-309; advance online publication, January 17, 2012; 10.1038/icb.2011.108 Abstract | Full Text |  | Theoretical Article | Top |  | A proposal for a simple and inexpensive therapeutic cancer vaccineAude M Fahrer Immunol Cell Biol 2012 90: 310-313; advance online publication, May 24, 2011; 10.1038/icb.2011.42 Abstract | Full Text |  | Original Articles | Top |  | Bacterial lipoprotein-induced tolerance is reversed by overexpression of IRAK-1Chong Hui Li, Jinghua Liu, Mingbang An, H Paul Redmond and Jiang Huai Wang Immunol Cell Biol 2012 90: 314-320; advance online publication, May 3, 2011; 10.1038/icb.2011.37 Abstract | Full Text |  |  |  | Mast cells reside in myometrium and cervix, but are dispensable in mice for successful pregnancy and laborFiona M Menzies, Claire A Higgins, Malcolm C Shepherd, Robert JB Nibbs and Scott M Nelson Immunol Cell Biol 2012 90: 321-329; advance online publication, May 17, 2011; 10.1038/icb.2011.40 Abstract | Full Text |  |  |  | Kinetics of ocular and systemic antigen-specific T-cell responses elicited during murine cytomegalovirus retinitisMartin S Zinkernagel, Claire Petitjean, Matthew E Wikstrom and Mariapia A Degli-Esposti Immunol Cell Biol 2012 90: 330-336; advance online publication, May 17, 2011; 10.1038/icb.2011.43 Abstract | Full Text |  |  |  | Regulation of mucosal mast cell activation by short interfering RNAs targeting syntaxin4Shuang Liu, Agung Endro Nugroho, Masachika Shudou and Kazutaka Maeyama Immunol Cell Biol 2012 90: 337-345; advance online publication, May 31, 2011; 10.1038/icb.2011.41 Abstract | Full Text |  |  |  | HIV-specific CD8+ T-cell proliferation is prospectively associated with delayed disease progressionLyle R McKinnon, Rupert Kaul, Joshua Kimani, Nico J Nagelkerke, Charles Wachihi, Keith R Fowke, Terry Blake Ball and Francis A Plummer Immunol Cell Biol 2012 90: 346-351; advance online publication, May 24, 2011; 10.1038/icb.2011.44 Abstract | Full Text |  |  |  | Toll-like receptor 2 siRNA suppresses corneal inflammation and attenuates Aspergillus fumigatus keratitis in ratsHui Guo, Jianlu Gao and Xinyi Wu Immunol Cell Biol 2011 90: 352-357; advance online publication, June 7, 2011; 10.1038/icb.2011.49 Abstract | Full Text |  |  |  | Sclerodermatous chronic graft-versus-host disease induced by host T-cell-mediated autoimmunityYou Jeong Lee, Hye Sook Min, Eun Ha Kang, Hyo Jin Park, Yoon Kyung Jeon, Ju Hyun Kim, Hong Gyun Wu, Eun-Bong Lee, Chung-Gyu Park, Sung-Soo Yoon, Seong Hoe Park and Kyeong Cheon Jung Immunol Cell Biol 2011 90: 358-367; advance online publication, May 31, 2011; 10.1038/icb.2011.46 Abstract | Full Text |  |  |  |  |  | | Advertisement |  | |
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