Scientific Reports Biology Table of Contents e-alert: February 2012

01 February 2012      • Visit Scientific Reports • Submit your manuscript to Scientific Reports     Welcome to your Table of Contents e-alert for Scientific Reports           Nature Reviews Neuroscience FOCUS ON ADDICTION Read for FREE online at: www.nature.com/nrn/focus/addiction Produced with support from National Institute on Drug Abuse (NIDA) and National Institute on Alcohol Abuse and Alcoholism (NIAAA) National Institutes of Health U.S. Department of Health & Human Services             Biological Sciences               Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration ▶     Charles-Peter Xavier, Raphael H. Rastetter, Margit Blömacher et al.     CRN2 (synonyms: coronin 1C, coronin 3) functions in the re-organization of the actin network and is implicated in cellular processes like protrusion formation, secretion, …             Success of a suicidal defense strategy against infection in a structured habitat ▶     Masaki Fukuyo, Akira Sasaki, Ichizo Kobayashi     Pathogen infection often leads to the expression of virulence and host death when the host-pathogen symbiosis seems more beneficial for the pathogen. Previously proposed …             Short Co-occurring Polypeptide Regions Can Predict Global Protein Interaction Maps ▶     Sylvain Pitre, Mohsen Hooshyar, Andrew Schoenrock et al.     A goal of the post-genomics era has been to elucidate a detailed global map of protein-protein interactions (PPIs) within a cell. Here, we show that the presence of co-occurring …             Functional analysis of missense variants in the TRESK (KCNK18) K+ channel ▶     Isabelle Andres-Enguix, Lijun Shang, Phillip J. Stansfeld et al.     A loss of function mutation in the TRESK K2P potassium channel (KCNK18), has recently been linked with typical familial migraine with aura. We now report the functional …             Neck-motor interactions trigger rotation of the kinesin stalk ▶     Hong-Lei Liu, Charles W. Pemble IV, Sharyn A. Endow     Rotation of the coiled-coil stalk of the kinesin-14 motors is thought to drive displacements or steps by the motor along microtubules, but the structural changes that trigger …             Road to evolution? Local adaptation to road adjacency in an amphibian (Ambystoma maculatum) ▶     Steven P. Brady     The network of roads on the landscape is vast, and contributes a suite of negative ecological effects on adjacent habitats, ranging from fragmentation to contamination by runoff. …             Impact of Intestinal Microbiota on Intestinal Luminal Metabolome ▶     Mitsuharu Matsumoto, Ryoko Kibe, Takushi Ooga et al.     Low–molecular-weight metabolites produced by intestinal microbiota play a direct role in health and disease. In this study, we analyzed the colonic luminal metabolome using …             Dynamical robustness in complex networks: the crucial role of low-degree nodes ▶     Gouhei Tanaka, Kai Morino, Kazuyuki Aihara     Many social, biological, and technological networks consist of a small number of highly connected components (hubs) and a very large number of loosely connected components …             The precision of axon targeting of mouse olfactory sensory neurons requires the BACE1 protease ▶     Luxiang Cao, Gregory T. Rickenbacher, Steve Rodriguez et al.     The β-site amyloid precursor protein cleaving enzyme 1 (BACE1) is necessary to generate the Aβ peptide, which is implicated in Alzheimer's disease pathology. Studies show that the …             Collagen based magnetic nanocomposites for oil removal applications ▶     Palanisamy Thanikaivelan, Narayanan T. Narayanan, Bhabendra K. Pradhan et al.     A stable magnetic nanocomposite of collagen and superparamagnetic iron oxide nanoparticles (SPIONs) is prepared by a simple process utilizing protein wastes from leather industry. …             Incipient speciation in Drosophila melanogaster involves chemical signals ▶     Micheline Grillet, Claude Everaerts, Benjamin Houot et al.     The sensory and genetic bases of incipient speciation between strains of Drosophila melanogaster from Zimbabwe and those from elsewhere are unknown. We studied mating behaviour …             A transgenic mouse model for monitoring oxidative stress ▶     Daisuke Oikawa, Ryoko Akai, Mio Tokuda et al.     Oxidative stress conditions enhance the production of reactive oxygen species resulting from a variety of stimuli, and are associated with various human diseases, including …             Recruitment in the sea: bacterial genes required for inducing larval settlement in a polychaete worm ▶     Ying Huang, Sean Callahan, Michael G. Hadfield     Metamorphically competent larvae of the marine tubeworm Hydroides elegans can be induced to metamorphose by biofilms of the bacterium Pseudoalteromonas luteoviolacea strain HI1. …             Fine-Scale Temporal Dynamics of a Fragmented Lotic Microbial Ecosystem ▶     Amitai Or, Lilach Shtrasler, Uri Gophna     Microbial ecosystems are often assumed to be relatively stable over short periods of time, but this assumption is seldom tested. An urban stream influenced by both flow and …             A Gene Signature for Predicting Outcome in Patients with Basal-like Breast Cancer ▶     Robin M. Hallett, Anna Dvorkin-Gheva, Anita Bane et al.     Basal-like breast cancer is a molecular subtype of breast cancer with a poor prognosis. Follow-up studies of long-term outcome in these patients, demonstrates they can be …             Origin and differentiation of breast nipple syringoma ▶     Werner Boecker, Tina Junkers, Michael Reusch et al.     Similarities in morphology and in glandular and squamous differentiation patterns amongst syringomas of the breast nipple and of the skin suggest a common nature, but the origin …             NMDA receptors and BAX are essential for Aβ impairment of LTP ▶     Kimberly Moore Olsen, Morgan Sheng     Accumulation of amyloid-β (Aβ) is a hallmark of Alzheimer’s disease, a neurodegenerative disorder in which synapse loss and dysfunction are early features. Acute exposure of …             Accurate RT-qPCR gene expression analysis on cell culture lysates ▶     Gert Van Peer, Pieter Mestdagh, Jo Vandesompele     Gene expression quantification on cultured cells using the reverse transcription quantitative polymerase chain reaction (RT-qPCR) typically involves an RNA purification step that …             Histone Deacetylase Inhibitors Globally Enhance H3/H4 Tail Acetylation Without Affecting H3 Lysine 56 Acetylation ▶     Paul Drogaris, Valérie Villeneuve, Christelle Pomiès et al.     Histone deacetylase inhibitors (HDACi) represent a promising avenue for cancer therapy. We applied mass spectrometry (MS) to determine the impact of clinically relevant HDACi on …             Visual motion with pink noise induces predation behaviour ▶     Wataru Matsunaga, Eiji Watanabe     Visual motion cues are one of the most important factors for eliciting animal behaviour, including predator-prey interactions in aquatic environments. To understand the elements …             Multifunctional CD4 T Cell Responses in Patients with Active Tuberculosis ▶     Zhengang Qiu, Mingxia Zhang, Yuzhen Zhu et al.     The roles of multifunctional CD4 T cells in human tuberculosis are not well defined. In this study, we found that patients with tuberculosis had decreased PMA/ionomycin stimulated …             Discrimination of the oral microbiota associated with high hydrogen sulfide and methyl mercaptan production ▶     Toru Takeshita, Nao Suzuki, Yoshio Nakano et al.     Both hydrogen sulfide (H2S) and methyl mercaptan (CH3SH) are frequently detected in large amounts in malodorous mouth air. We investigated the bacterial composition of saliva of …             A novel platform to enable the high-throughput derivation and characterization of feeder-free human iPSCs ▶     Bahram Valamehr, Ramzey Abujarour, Megan Robinson et al.     Human induced pluripotent stem cells (hiPSCs) hold enormous potential, however several obstacles impede their translation to industrial and clinical applications. Here we describe …             Drosophila growth-blocking peptide-like factor mediates acute immune reactions during infectious and non-infectious stress ▶     Seiji Tsuzuki, Masanori Ochiai, Hitoshi Matsumoto et al.     Antimicrobial peptides (AMPs), major innate immune effectors, are induced to protect hosts against invading microorganisms. AMPs are also induced under non-infectious stress; …             CUGBP1 and MBNL1 preferentially bind to 3′ UTRs and facilitate mRNA decay ▶     Akio Masuda, Henriette Skovgaard Andersen, Thomas Koed Doktor et al.     CUGBP1 and MBNL1 are developmentally regulated RNA-binding proteins that are causally associated with myotonic dystrophy type 1. We globally determined the in vivo RNA-binding …             Zscan4 transiently reactivates early embryonic genes during the generation of induced pluripotent stem cells ▶     Tetsuya Hirata, Tomokazu Amano, Yuhki Nakatake et al.     The generation of induced pluripotent stem cells (iPSCs) by the forced expression of defined transcription factors in somatic cells holds great promise for the future of …                         Scientific Reports is accepting submissions from all scientific fields. 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