Thursday, February 9, 2012

Gene Therapy - Table of Contents alert Volume 19 Issue 2

Special Issue: Gene Therapy for Eye Diseases


Guest Editor Robin R Ali, University College London, United Kingdom

Over the last decade it has become increasingly clear that eye disorders are amongst the most amenable targets for gene therapy. This issue surveys ocular gene transfer using AAV and lentiviral vectors which are the most effective vector platforms for the eye and also surveys gene therapy approaches for the treatment of a range of retinal disorders, including inherited retinopathies, glaucoma and retinal and choroidal neovascularisation.

TABLE OF CONTENTS

Volume 19, Issue 2 (February 2012)

In this issue
Editorial
Reviews
Short Communications
Enabling Technologies
Original Articles
Erratum

Also new
AOP

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Editorial

Top

Ocular gene therapy: introduction to the special issue

R R Ali

Gene Ther 2012 19: 119-120; 10.1038/gt.2011.189

Full Text | PDF

Reviews

Top

Gene transfer for ocular neovascularization and macular edema

P A Campochiaro

Gene Ther 2012 19: 121-126; advance online publication, November 10, 2011; 10.1038/gt.2011.164

Abstract | Full Text

Gene therapy for retinal ganglion cell neuroprotection in glaucoma

A M Wilson and A Di Polo

Gene Ther 2012 19: 127-136; advance online publication, October 6, 2011; 10.1038/gt.2011.142

Abstract | Full Text

Gene-based therapies for dominantly inherited retinopathies

G J Farrar, S Millington-Ward, N Chadderton, P Humphries and P F Kenna

Gene Ther 2012 19: 137-144; advance online publication, November 17, 2011; 10.1038/gt.2011.172

Abstract | Full Text

Ocular gene delivery using lentiviral vectors

K S Balaggan and R R Ali

Gene Ther 2012 19: 145-153; advance online publication, November 3, 2011; 10.1038/gt.2011.153

Abstract | Full Text

Gene supplementation therapy for recessive forms of inherited retinal dystrophies

A J Smith, J W B Bainbridge and R R Ali

Gene Ther 2012 19: 154-161; advance online publication, October 27, 2011; 10.1038/gt.2011.161

Abstract | Full Text

Novel adeno-associated viral vectors for retinal gene therapy

L H Vandenberghe and A Auricchio

Gene Ther 2012 19: 162-168; advance online publication, October 13, 2011; 10.1038/gt.2011.151

Abstract | Full Text

Optogenetic therapy for retinitis pigmentosa

V Busskamp, S Picaud, J A Sahel and B Roska

Gene Ther 2012 19: 169-175; advance online publication, October 13, 2011; 10.1038/gt.2011.155

Abstract | Full Text

Short Communications

Top

Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9

D Dalkara, L C Byrne, T Lee, N V Hoffmann, D V Schaffer and J G Flannery

Gene Ther 2012 19: 176-181; advance online publication, October 20, 2011; 10.1038/gt.2011.163

Abstract | Full Text

Absence of ocular malignant transformation after sub-retinal delivery of rAAV2/2 or integrating lentiviral vectors in p53-deficient mice

K S Balaggan, Y Duran, A Georgiadis, C Thaung, S E Barker, P K Buch, A MacNeil, S Robbie, J W B Bainbridge, A J Smith and R R Ali

Gene Ther 2012 19: 182-188; advance online publication, November 24, 2011; 10.1038/gt.2011.194

Abstract | Full Text

Enabling Technologies

Top

Targeted suicide gene therapy for glioma using human embryonic stem cell-derived neural stem cells genetically modified by baculoviral vectors

Y Zhao, D H Lam, J Yang, J Lin, C K Tham, W H Ng and S Wang

Gene Ther 2012 19: 189-200; advance online publication, June 2, 2011; 10.1038/gt.2011.82

Abstract | Full Text

Original Articles

Top

Jaagsiekte sheep retrovirus pseudotyped lentiviral vector-mediated gene transfer to fetal ovine lung

M G Davey, P W Zoltick, C A Todorow, M P Limberis, E D Ruchelli, H L Hedrick and A W Flake

Gene Ther 2012 19: 201-209; advance online publication, June 9, 2011; 10.1038/gt.2011.83

Abstract | Full Text

Successful target cell transduction of capsid-engineered rAAV vectors requires clathrin-dependent endocytosis

S Uhrig, O Coutelle, T Wiehe, L Perabo, M Hallek and H Büning

Gene Ther 2012 19: 210-218; advance online publication, June 9, 2011; 10.1038/gt.2011.78

Abstract | Full Text

Regulation of gene expression in prostate cancer cells with an artificially constructed promoter responsive to radiation

A Morii, R Ogawa, A Watanabe, S Kakutani, Q L Zhao, K Kume, T Kondo and H Fuse

Gene Ther 2012 19: 219-227; advance online publication, June 23, 2011; 10.1038/gt.2011.89

Abstract | Full Text

Experimental autoimmune hearing loss is exacerbated in IL-10-deficient mice and reversed by IL-10 gene transfer

B Zhou, M H Kermany, Q Cai, C Cai, Y Zhou, U Nair, W Liu and T J Yoo

Gene Ther 2012 19: 228-235; advance online publication, June 23, 2011; 10.1038/gt.2011.88

Abstract | Full Text

Erratum

Top

Novel adeno-associated viral vectors for retinal gene therapy

L H Vandenberghe and A Auricchio

Gene Ther 2012 19: 236; advance online publication, November 24, 2011; 10.1038/gt.2011.199

Full Text

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