Special Issue: Gene Therapy for Eye Diseases |
|  | Guest Editor Robin R Ali, University College London, United Kingdom Over the last decade it has become increasingly clear that eye disorders are amongst the most amenable targets for gene therapy. This issue surveys ocular gene transfer using AAV and lentiviral vectors which are the most effective vector platforms for the eye and also surveys gene therapy approaches for the treatment of a range of retinal disorders, including inherited retinopathies, glaucoma and retinal and choroidal neovascularisation. |  | TABLE OF CONTENTS
|  |  |  | Volume 19, Issue 2 (February 2012) |  | In this issue
Editorial
Reviews
Short Communications
Enabling Technologies
Original Articles
Erratum
Also new
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|  | | Editorial | Top |  | Ocular gene therapy: introduction to the special issueR R Ali Gene Ther 2012 19: 119-120; 10.1038/gt.2011.189 Full Text | PDF |  | Reviews | Top |  | Gene transfer for ocular neovascularization and macular edemaP A Campochiaro Gene Ther 2012 19: 121-126; advance online publication, November 10, 2011; 10.1038/gt.2011.164 Abstract | Full Text |  |  |  | Gene therapy for retinal ganglion cell neuroprotection in glaucomaA M Wilson and A Di Polo Gene Ther 2012 19: 127-136; advance online publication, October 6, 2011; 10.1038/gt.2011.142 Abstract | Full Text |  |  |  | Gene-based therapies for dominantly inherited retinopathiesG J Farrar, S Millington-Ward, N Chadderton, P Humphries and P F Kenna Gene Ther 2012 19: 137-144; advance online publication, November 17, 2011; 10.1038/gt.2011.172 Abstract | Full Text |  |  |  | Ocular gene delivery using lentiviral vectorsK S Balaggan and R R Ali Gene Ther 2012 19: 145-153; advance online publication, November 3, 2011; 10.1038/gt.2011.153 Abstract | Full Text |  |  |  | Gene supplementation therapy for recessive forms of inherited retinal dystrophiesA J Smith, J W B Bainbridge and R R Ali Gene Ther 2012 19: 154-161; advance online publication, October 27, 2011; 10.1038/gt.2011.161 Abstract | Full Text |  |  |  | Novel adeno-associated viral vectors for retinal gene therapyL H Vandenberghe and A Auricchio Gene Ther 2012 19: 162-168; advance online publication, October 13, 2011; 10.1038/gt.2011.151 Abstract | Full Text |  |  |  | Optogenetic therapy for retinitis pigmentosaV Busskamp, S Picaud, J A Sahel and B Roska Gene Ther 2012 19: 169-175; advance online publication, October 13, 2011; 10.1038/gt.2011.155 Abstract | Full Text |  | Short Communications | Top |  | Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9D Dalkara, L C Byrne, T Lee, N V Hoffmann, D V Schaffer and J G Flannery Gene Ther 2012 19: 176-181; advance online publication, October 20, 2011; 10.1038/gt.2011.163 Abstract | Full Text |  |  |  | Absence of ocular malignant transformation after sub-retinal delivery of rAAV2/2 or integrating lentiviral vectors in p53-deficient miceK S Balaggan, Y Duran, A Georgiadis, C Thaung, S E Barker, P K Buch, A MacNeil, S Robbie, J W B Bainbridge, A J Smith and R R Ali Gene Ther 2012 19: 182-188; advance online publication, November 24, 2011; 10.1038/gt.2011.194 Abstract | Full Text |  | Enabling Technologies | Top |  | Targeted suicide gene therapy for glioma using human embryonic stem cell-derived neural stem cells genetically modified by baculoviral vectorsY Zhao, D H Lam, J Yang, J Lin, C K Tham, W H Ng and S Wang Gene Ther 2012 19: 189-200; advance online publication, June 2, 2011; 10.1038/gt.2011.82 Abstract | Full Text |  | Original Articles | Top |  | Jaagsiekte sheep retrovirus pseudotyped lentiviral vector-mediated gene transfer to fetal ovine lungM G Davey, P W Zoltick, C A Todorow, M P Limberis, E D Ruchelli, H L Hedrick and A W Flake Gene Ther 2012 19: 201-209; advance online publication, June 9, 2011; 10.1038/gt.2011.83 Abstract | Full Text |  |  |  | Successful target cell transduction of capsid-engineered rAAV vectors requires clathrin-dependent endocytosisS Uhrig, O Coutelle, T Wiehe, L Perabo, M Hallek and H Büning Gene Ther 2012 19: 210-218; advance online publication, June 9, 2011; 10.1038/gt.2011.78 Abstract | Full Text |  |  |  | Regulation of gene expression in prostate cancer cells with an artificially constructed promoter responsive to radiationA Morii, R Ogawa, A Watanabe, S Kakutani, Q L Zhao, K Kume, T Kondo and H Fuse Gene Ther 2012 19: 219-227; advance online publication, June 23, 2011; 10.1038/gt.2011.89 Abstract | Full Text |  |  |  | Experimental autoimmune hearing loss is exacerbated in IL-10-deficient mice and reversed by IL-10 gene transferB Zhou, M H Kermany, Q Cai, C Cai, Y Zhou, U Nair, W Liu and T J Yoo Gene Ther 2012 19: 228-235; advance online publication, June 23, 2011; 10.1038/gt.2011.88 Abstract | Full Text |  | Erratum | Top |  | Novel adeno-associated viral vectors for retinal gene therapyL H Vandenberghe and A Auricchio Gene Ther 2012 19: 236; advance online publication, November 24, 2011; 10.1038/gt.2011.199 Full Text |  |  |  |  |  | Advertisement |  | |
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