SPECIAL FEATURE: Histone Deacetylases and their Inhibitors in Immunology |
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Histone deacetylases (HDAC) have been strongly associated with epigenetics and cancer development and several inhibitors are used in the treatment of certain types of cancers. The January 2012 issue will bring together a series of review articles focussing on the roles of specific histone deacetylases (HDAC) and their inhibitors in immunology and immune-related diseases. Further background information about these enzymes is available through the accompanying web focus which links to related articles across the Nature Publishing Group. |
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TABLE OF CONTENTS
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Volume 90, Issue 1 (January 2012) |
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Obituary | Top |
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Ralph Steinman and dendritic cellsKen Shortman Immunol Cell Biol 2012 90: 1-2; advance online publication, October 25, 2011; 10.1038/icb.2011.91 Full Text |
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Editorial | Top |
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HDACs and their inhibitors in immunology: teaching anticancer drugs new tricksDavid P Fairlie and Matthew J Sweet Immunol Cell Biol 2012 90: 3-5; 10.1038/icb.2011.105 Full TextPDF |
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Reviews | Top |
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Sirtuin 1 in immune regulation and autoimmunitySinyi Kong, Michael W McBurney and Deyu Fang Immunol Cell Biol 2012 90: 6-13; advance online publication, November 22, 2011; 10.1038/icb.2011.102 Abstract | Full Text |
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HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammationMatthew J Sweet, Melanie R Shakespear, Nabilah A Kamal and David P Fairlie Immunol Cell Biol 2012 90: 14-22; advance online publication, October 25, 2011; 10.1038/icb.2011.88 Abstract | Full Text |
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HDACi: molecular mechanisms and therapeutic implications in the innate immune systemBandar Ali Suliman, Dakang Xu and Bryan RG Williams Immunol Cell Biol 2012 90: 23-32; advance online publication, November 15, 2011; 10.1038/icb.2011.92 Abstract | Full Text |
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Histone deacetylase inhibitors in the generation of the anti-tumour immune responseGraham R Leggatt and Brian Gabrielli Immunol Cell Biol 2012 90: 33-38; advance online publication, November 8, 2011; 10.1038/icb.2011.94 Abstract | Full Text |
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Lysine acetylation in obesity, diabetes and metabolic diseaseAbishek Iyer, David P Fairlie and Lindsay Brown Immunol Cell Biol 2012 90: 39-46; advance online publication, November 15, 2011; 10.1038/icb.2011.99 Abstract | Full Text |
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HDAC inhibitors in HIVFiona Wightman, Paula Ellenberg, Melissa Churchill and Sharon R Lewin Immunol Cell Biol 2012 90: 47-54; advance online publication, November 15, 2011; 10.1038/icb.2011.95 Abstract | Full Text |
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Modulation of antigen-presenting cells by HDAC inhibitors: implications in autoimmunity and cancerKarrune V Woan, Eva Sahakian, Eduardo M Sotomayor, Edward Seto and Alejandro Villagra Immunol Cell Biol 2012 90: 55-65; advance online publication, November 22, 2011; 10.1038/icb.2011.96 Abstract | Full Text |
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HDAC inhibitors in parasitic diseasesKatherine T Andrews, Ashraful Haque and Malcolm K Jones Immunol Cell Biol 2012 90: 66-77; advance online publication, November 29, 2011; 10.1038/icb.2011.97 Abstract | Full Text |
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Interplay between histone deacetylases and autophagy - from cancer therapy to neurodegenerationOliver Trüe and Patrick Matthias Immunol Cell Biol 2012 90: 78-84; advance online publication, November 29, 2011; 10.1038/icb.2011.103 Abstract | Full Text |
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HDAC inhibitors in cancer biology: emerging mechanisms and clinical applicationsOmar Khan and Nicholas B La Thangue Immunol Cell Biol 2012 90: 85-94; advance online publication, November 29, 2011; 10.1038/icb.2011.100 Abstract | Full Text |
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Immune regulation by histone deacetylases: a focus on the alteration of FOXP3 activityHongtao Zhang, Yan Xiao, Zhiqiang Zhu, Bin Li and Mark I Greene Immunol Cell Biol 2012 90: 95-100; advance online publication, November 29, 2011; 10.1038/icb.2011.101 Abstract | Full Text |
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Original Articles | Top |
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Absence of scavenger receptor A promotes dendritic cell-mediated cross-presentation of cell-associated antigen and antitumor immune responseChunqing Guo, Huanfa Yi, Xiaofei Yu, Fanlei Hu, Daming Zuo, John R Subjeck and Xiang-Yang Wang Immunol Cell Biol 2012 90: 101-108; advance online publication, March 8, 2011; 10.1038/icb.2011.10 Abstract | Full Text |
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Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patientsBeatriz Sanchez-Correa, Inmaculada Gayoso, Juan M Bergua, Javier G Casado, Sara Morgado, Rafael Solana and Raquel Tarazona Immunol Cell Biol 2012 90: 109-115; advance online publication, March 8, 2011; 10.1038/icb.2011.15 Abstract | Full Text |
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Rapid death of duck cells infected with influenza: a potential mechanism for host resistance to H5N1Suresh V Kuchipudi, Stephen P Dunham, Rahul Nelli, Gavin A White, Vivien J Coward, Marek J Slomka, Ian H Brown and Kin Chow Chang Immunol Cell Biol 2012 90: 116-123; advance online publication, March 22, 2011; 10.1038/icb.2011.17 Abstract | Full Text |
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IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3Ben A Croker, Hiu Kiu, Marc Pellegrini, Jesse Toe, Simon Preston, Donald Metcalf, Joanne A O'Donnell, Louise H Cengia, Kate McArthur, Nicos A Nicola, Warren S Alexander and Andrew W Roberts Immunol Cell Biol 2012 90: 124-129; advance online publication, April 26, 2011; 10.1038/icb.2011.29 Abstract | Full Text |
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Short Communication | Top |
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Reinforcement of cancer immunotherapy by adoptive transfer of cblb-deficient CD8+ T cells combined with a DC vaccineChristina Lutz-Nicoladoni, Stephanie Wallner, Patrizia Stoitzner, Magdalena Pircher, Thomas Gruber, Anna Maria Wolf, Günther Gastl, Josef M Penninger, Gottfried Baier and Dominik Wolf Immunol Cell Biol 2012 90: 130-134; advance online publication, March 8, 2011; 10.1038/icb.2011.11 Abstract | Full Text |
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