  | Today's Top Story |  |  | |  |  |  | | See how Cardmembers use American Express OPEN Cards to help run their business:
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  - EU approves Roche's Avastin to treat ovarian cancer
The European Commission approved the use of Roche Holding's Avastin plus standard chemotherapy for women newly diagnosed with metastatic ovarian cancer. Patients given the combination during two late-stage studies survived longer without disease progression than the chemotherapy-only group. Reuters (12/23)       - Marina, Mirna to develop mRNA-based therapeutics
Marina Biotech and Mirna Therapeutics will jointly develop and commercialize microRNA-based drugs using proprietary microRNAs from Mirna and Smarticles liposomal delivery technology from Marina. The licensing deal gives Mirna the right to develop and market any products that result from the collaboration while Marina Biotech will provide preclinical and process development support. Marina could get as much as $63 million in milestone payments and royalties. Pharmaceutical Business Review Online (12/26) - Scientists link mutations to PKD/IC
A group of international researchers found that the gene PRRT2 is the cause of paroxysmal kinesigenic dyskinesia with infantile convulsions, a rare neurological disorder that results in epilepsy in infants and movement disorders in older kids. The study could lead to better diagnostic tools for PKD/IC and give researchers insight into Parkinson's disease and other movement disorders. Medical News Today (12/25)  | Your job as an Exchange administrator isn't easy. You have to respond to lost messages, handle email discovery requirements, and keep everything up and running. Is there an easy way to manage your Exchange environment — and do it under budget? Learn about the challenges faced by three real organizations, and how using the right solution brought them peace of mind. |
 - Provenance gets $8M from Alopexx
Provenance Biopharmaceuticals has secured $8 million in funding from Alopexx Enterprises. Provenance will use the money for the development of its drug candidate DI-Leu16-IL2, which is being studied for hematological cancers including non-Hodgkin lymphoma. A new firm named Alopexx Oncology will handle development of the immunotherapeutic. Genetic Engineering & Biotechnology News (12/23)  | Let’s Go Design: Episode #7
Before moving into the last stage of production, the team calls a last minute “sanity check” on the final design of the hot rod baby buggy. They look at each of the main components to make sure it rides smoothly. Watch them at work at LetsGoDesign.tv |
 | | | Most Popular Headlines from Last Week Results based on number of times each story was clicked by readers. |
| Hot Topics | | | | Top five news stories selected by BIO SmartBrief readers in the past week. - Results based on number of times each story was clicked by readers.
| Industrial & Environmental | | | | - Dinneen: Ethanol sector can grow without the VEETC, import tariff
Ethanol groups are optimistic that the industry will continue to thrive even without the blender's tax credit and the tariff on imported ethanol, which are both due to expire Dec. 31. The sector is planning to expand its market by pushing for higher blends and more blender pumps and flexible-fuel vehicles. "I would expect continued growth," said Bob Dinneen, president and CEO of the Renewable Fuels Association. CattleNetwork.com/Reuters (12/22) | News from BIO | | | | - Are you taking full advantage of your membership?
BIO's cost-savings program, BIO Business Solutions, is helping 2,700 companies nationwide save on the cost of essential products and services. Members of BIO and 43 state and regional biotech associations are eligible to receive preferential pricing and other benefits at no additional cost beyond their membership dues. VWR International, FedEx, Office Depot and Business Wire are just a few of the industry leading providers that offer special pricing through this members-only program. Learn more or enroll here.
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