  | Today's Top Story |  |  | | - Alexion will take over Enobia for as much as $1.08 billion
Alexion Pharmaceuticals agreed to purchase Canada's Enobia Pharma for $610 million in cash, plus as much as $470 million in milestone fees. The transaction is expected to be finalized during the first quarter. Enobia is working on a hypophosphatasia treatment, ENB-0040, that has orphan-drug and fast-track designation in the U.S. The Wall Street Journal (12/28)        | See how Cardmembers use American Express OPEN Cards to help run their business:
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  - Scientists work on stem cell treatment for hearing loss
British researchers will try to grow and transplant cells into the ear to prevent age-related hearing loss. "If we can find a way to replace fibrocytes through stem cell therapy when they start to degenerate, but before other parts of the inner ear get damaged, we could potentially have found a way to prevent age related hearing loss," researcher Dave Furness of Keele University said. The Telegraph (London) (12/28) - Gene variants tied to weight regain, loss in obese
The Ala12 allele at PPARG is associated with long- and short-term weight reduction in overweight or obese patients regardless of their weight-loss treatment, a study showed. Researchers also found three gene variants linked to weight regain in patients, regardless of treatment, and two others that were linked to outcomes dependent on treatment. The findings appear in Diabetes Care. PhysiciansBriefing.com/HealthDay News (12/28) - Study links Tbx3 gene to heart arrhythmia
Researchers discovered that a gene called Tbx3 may interfere with cardiac conduction, potentially causing heart arrhythmia. The study, published in the Proceedings of the National Academy of Sciences, showed that increasing Tbx3 protein resulted in irregular heartbeat or sudden death in mice. DailyRx.com (12/28)  | Let’s Go Design: Episode #7
Before moving into the last stage of production, the team calls a last minute “sanity check” on the final design of the hot rod baby buggy. They look at each of the main components to make sure it rides smoothly. Watch them at work at LetsGoDesign.tv |
 - Mass. biotech center loans $2.2M to 3 life science startups
Intelligent Bio-Systems and Allurion Technologies will each receive up to $750,000 in loans under the Accelerator Program of the Massachusetts Life Sciences Center. Paragonix Technologies, meanwhile, got $710,000. "We are pleased to add these three promising companies to the Center's investment portfolio," center executive Susan Windham-Bannister said. Boston Herald (12/28)  | How will IM, video, telephony and other elements of UC change in the coming year? This set of products provides a consistent unified user interface and experience and is poised to become more widespread in the enterprise. Get insight from Focus Experts as they share their predictions for Unified Communications in this free guide. |
 | Industry Deals | | | | - Biotech startup raises $5 million in financing round
 Daktari Diagnostics said in a regulatory filing that it has secured $5 million in a funding round. The Cambridge, Mass.-based startup is developing a point-of-care HIV test capable of making crucial CD4 white blood cell counts that can be used to evaluate AIDS therapies in the developing world. Mass High Tech (Boston) (12/28)  | |  | | The Buzz(CORPORATE ANNOUNCEMENTS)
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| Food & Agriculture | | | | | Industrial & Environmental | | | | - Ethanol is ranked third among biofuels trends of 2011
Ethanol ranked third in Biofuels Digest's top 11 biofuels trends of 2011 as the fuel gained popularity this year among advanced-biofuels manufacturers. The list also includes the filing of initial public offerings among renewable-products companies, the use of aviation biofuels and the development of algal biofuels in Australia. BiofuelsDigest.com (12/27) | News from BIO | | | | - Are you taking full advantage of your membership?
BIO's cost-savings program, BIO Business Solutions, is helping 2,700 companies nationwide save on the cost of essential products and services. Members of BIO and 43 state and regional biotech associations are eligible to receive preferential pricing and other benefits at no additional cost beyond their membership dues. VWR International, FedEx, Office Depot and Business Wire are just a few of the industry leading providers that offer special pricing through this members-only program. Learn more or enroll here.
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