Tuesday, December 13, 2011

Abbott, Reata form $400M licensing deal

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December 13, 2011
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  Today's Top Story 
 
  • Abbott, Reata form $400M deal for second-generation AIMs
    Reata Pharmaceuticals stands to receive $400 million from Abbott Laboratories as part of a research and development agreement centered on Reata's second-generation oral antioxidant inflammation modulators. The firms will co-develop the compounds and evenly split costs and profit for all compounds in all indications, excluding rheumatoid arthritis and certain autoimmune disorders. The agreement also calls for joint discovery of molecules with pharmacology similar to Reata's AIMs. PharmaTimes (U.K.) (12/12) LinkedInFacebookTwitterEmail this Story
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  Health Care & Policy 
  • Leukemia patients with mutation respond to drug in trial
    Ariad Pharmaceuticals' drug candidate ponatinib induced a positive response in about 65% of chronic myeloid leukemia patients with a genetic mutation called T315I in a Phase II study. Ariad plans to submit ponatinib for approval in mid-2012. Bloomberg (12/12) LinkedInFacebookTwitterEmail this Story
  • Scientists find marker for precursors of blood stem cells
    Researchers have found a molecular marker for blood stem cell precursors, according to a study published in Cell Stem Cell. "Understanding the developmental origins of hematopoietic stem cells is important for learning how to produce them in the lab from embryonic or induced pluripotent stem cells," said lead researcher Nancy Speck from the University of Pennsylvania. Yahoo!/Asian News International (12/10) LinkedInFacebookTwitterEmail this Story
  • Peripheral blood stem cells from unrelated donors tied to greater risk
    Patients with various types of high-risk leukemia who received peripheral blood stem cells, or PBSCs, from unrelated donors did not show greater survival rates and had a higher chance of developing chronic graft-versus-host disease, or GVHD, compared with patients who received bone marrow transplants from unrelated donors, according to a recent study. While previous studies have shown PBSCs from related donors to have clinical advantages, the current findings indicate that PSBCs from unrelated donors can lead to a higher risk of contracting chronic GVHD without similar benefits, the researchers said. HemOnc Today (12/11) LinkedInFacebookTwitterEmail this Story
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  Company & Financial News 
 
  • Onyx shares decline after accelerated review decision
    Onyx Pharmaceuticals said the FDA set a July 27 target date for approval of multiple myeloma drug carfilzomib, denying an accelerated review. According to Onyx, the agency said the company hadn't undertaken clinical trials required for the quicker review. "We feel comfortable that we have addressed the key risks and that this is a compound that deserves to be approved either on an accelerated basis or a full basis," CEO Tony Coles said. Bloomberg Businessweek (12/13) LinkedInFacebookTwitterEmail this Story
  • Expansion planned at Fitzsimons biotech park in Colorado
    The Fitzsimons Redevelopment Authority in Colorado plans to spend $8 million to build a 37,000-square-foot "accelerator" facility at its Bioscience Park Center in Aurora. Authority official Denise Brown said the new facility will be rented to companies "in the modest growth stage." Five companies involved in the development of various therapeutic, diagnostic and medical device products have shown interest in renting space in the accelerator facility, said authority spokeswoman Vicki Jenings. The Denver Post (12/12) LinkedInFacebookTwitterEmail this Story
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  Global Developments 
  • Elan, Dublin university seal biotech partnership
    Elan has forged a pact with the University College Dublin in Ireland as part of efforts to establish "a leadership position in the global biotechnology industry," beginning with the creation of the first biotech interdisciplinary chair in Europe. As part of the alliance, the university will receive more than $3.9 million from Elan for a new science facility. "The biotechnology industry require future business leaders ... to manage a portfolio of assets within the environment of a dynamic and ever-changing risks/reward equation," Elan chief executive Kelly Martin said. PharmaTimes (U.K.) (12/12) LinkedInFacebookTwitterEmail this Story
  • India plans to map genome of coconut
    India's Coconut Development Board is planning to partner with a genetic engineering company to map the genome of the coconut. "Once the genome is identified, it will help us cultivate various breeds of coconut according to our needs. We can produce short varieties of coconut trees or increase quality and yield," said board Chairman T K Jose. The Times of India (12/13) LinkedInFacebookTwitterEmail this Story
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  Food & Agriculture 
  • Opinion: Africa needs biotechnology to solve food problems
    African governments must adopt biotech crops to boost food production and alleviate hunger in the region, Matt Ridley writes in this Wall Street Journal opinion piece. The article builds on a Science magazine editorial by Calestous Juma, director of Harvard Kennedy School's Agricultural Innovation in Africa program, who argues that Africa badly needs biotechnology since most farmers in the region lack access to pesticides. The Wall Street Journal (12/10) LinkedInFacebookTwitterEmail this Story
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