| | | TABLE OF CONTENTS 
 |  |  |  |  |  | Volume 1, November 2011 |  |  | In this issue 
  Original Articles 
  Letter to the Editor 
 
 |  |  |  |  |  |  |  |  | Advertisement |  |  |  |  |  |  |  |  |  | Original Articles |  Top |  |  |  | Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemiaS Hart, K C Goh, V Novotny-Diermayr, Y C Tan, B Madan, C Amalini, L C Ong, B Kheng, A Cheong, J Zhou, W J Chng and J M Wood Blood Cancer J 2011 1: e44; 10.1038/bcj.2011.43 Abstract | Full Text |  |  |  |  |  |  |  | FHL2 interacts with CALM and is highly expressed in acute erythroid leukemiaZ Pašaliç, P A Greif, V Jurinoviç, M Mulaw, P M Kakadia, B Tizazu, L Fröhlich-Archangelo, A Krause and S K Bohlander Blood Cancer J 2011 1: e42; 10.1038/bcj.2011.40 Abstract | Full Text |  |  |  |  |  |  |  | Analysis of genomic aberrations and gene expression profiling identifies novel lesions and pathways in myeloproliferative neoplasmsK L Rice, X Lin, K Wolniak, B L Ebert, W Berkofsky-Fessler, M Buzzai, Y Sun, C Xi, P Elkin, R Levine, T Golub, D G Gilliland, J D Crispino, J D Licht and W Zhang Blood Cancer J 2011 1: e40; 10.1038/bcj.2011.39 Abstract | Full Text |  |  |  | Letter to the Editor |  Top |  |  |  | Patients with chronic myeloid leukemia treated with imatinib who showed the appearance of clonal cytogenetic abnormalities in Philadelphia chromosome-negative cellsM M da Rocha, L Otero, T F Padilha, J Dobbin, C de Souza Fernandez, E Abdelhay and T de Souza Fernandez Blood Cancer J 2011 1: e45; 10.1038/bcj.2011.45 Full Text |  |  |  |  |  |  |  |  |  |  |  | Advertisement |  |  |  | | A personal note - 40 years after the signing of the Cancer Act FREE Nat. Rev. Clin. Oncol ¦ doi:10.1038/nrclinonc.2011.168
 
 The Cancer Act that was signed by President Nixon 40 years ago had a mandate “to support research and the application of the results of research, to reduce the incidence, morbidity and mortality from cancer.” It has succeeded in many of these aims by focusing on basic research, as this personal account from a former Director of the National Cancer Institute testifies.
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