Nature contents: 13 October 2011

Can't view this email? Click here to view in your browser.     Volume 478 Number 7368      nature •Visit Nature homepage •Subscribe to Nature •View Table of Contents The science that matters. Every week.                       RNA-Seq just went from complicated to compatible. EA will provide your data in a format you are used to -- 100% microarray compatible format. Now you can have your data and use it too! Expresssion Analysis will help you detect 2x more differentially expressed transcripts, novel isoforms and SNVs and can achieve >97% alignment to your reference genome. 919-405-2248             Jump to the content that matters to you View Table of Contents ▶ ▼ News & Comment   ▼ Biological Sciences   ▼ Chemical Sciences   ▼ Physical Sciences   ▼ Earth & Environmental Sciences   ▼ Careers & Jobs       This week's highlights     Physical Sciences More Physical sciences ▼   Ocean-like water in the Jupiter-family comet 103P/Hartley 2   The deuterium-to-hydrogen (D/H) ratio measured in the Kuiper-belt comet 103P/Hartley 2 is close to that seen in ocean waters here on Earth, fuelling the suspicion that some of 'our' water may have arrived in cometary impacts.       Earth & Environmental Sciences More Earth & Environmental sciences ▼   Atmospheric oxygenation caused by a change in volcanic degassing pressure   Two and a half billion years ago Earth's atmosphere was transformed in what is known as the Great Oxidation Event. Work with a model of volcanic degassing suggests that a shift of volcanic activity from a largely under-water affair to an open-air process may have been a key step towards the breathable atmosphere we have today.       Earth & Environmental Sciences More Earth & Environmental sciences ▼   Strong contributors to network persistence are the most vulnerable to extinction   In cooperative networks - whether between plants and their pollinators or service providers and customers - it is the nodes that contribute to the nestedness of the network that improve its stability. But strangely, a study of 20 plant-pollinator partnerships and various socioeconomic networks, shows that these same nodes are also the most vulnerable to extinction.                   Speed. Resolution. Sensitivity. Accuracy. Hamamatsu's NanoZoomer 2.0 Series delivers all this and more. The ultimate scientific digital image-maker and virtual microscopy tool, the NanoZoomer converts glass slides into digital slides quickly and accurately, making it perfect for viewing and analyzing slide-mounted tissue at any resolution. Get reliable scanning 24/7/365 in brightfield or fluorescence at the touch of a button.                 Podcast & Video     In this week's podcast: The secrets of the Black Death bacterium, local knowledge helps scientists study the Arctic, and the genome of the naked mole rat - ugly as sin, but long-lived and cancer-resistant.       Specials - Outlook: Biomedical research masterclass     Each year, the world's finest scientific minds, from Nobel laureates to aspiring young researchers, meet on the picturesque German island of Lindau to engage one another about the practice of their craft. Nature Outlook examines the areas of biomedical science that challenge and inspire these pre-eminent investigators. ▼ more       Special: After the ice     The Arctic ice is melting, and with it go many of the old assumptions about how science should be conducted in the Arctic Circle. In the series of News Features and Comment pieces in this issue, we chart the changing picture of Arctic science, as well as the political and environmental consequences of the retreating ice.         News & Comment Read daily news coverage▶ ▲top             THIS WEEK           Editorials                   The case of Dr Hicheur ▶     The continued imprisonment of a French-Algerian physicist highlights the need for scientists to defend the human rights of all colleagues.             An eye for success ▶     Steve Jobs and Apple revolutionized the way scientists render their work.             More than teeth ▶     The bizarre-looking naked mole rat is a worthy member of the genome club.             World View                   Marine protection in the Arctic cannot wait ▶     Global economics, not declining sea ice, is driving ships to the Arctic Ocean. Only international regulation will protect the region, says Lawson Brigham.             Seven Days                   Seven days: 7-13 October 2011 ▶     The week in science           NEWS IN FOCUS           A fight for life that united a field ▶     Nobel-prizewinner Ralph Steinman tried to beat his cancer with vaccines based on the dendritic cells he discovered.             Persistence pays off for crystal chemist ▶     Discovery of mosaic material wins Nobel prize.             Sun-watchers hope giant telescope will get green light ▶     Observatory would reveal structures that trigger sunspots and space weather.             Brazil cooks up transgenic bean ▶     Approval draws criticism over transparency and safety tests.             France toughens conflict rules ▶     Law demands greater transparency for health experts.             Features                   Special issue on the Arctic: After the ice ▶     As the Arctic thaws, can science help to chart a sustainable path for the north?             Redrawing the Arctic map: The new north ▶             Scientific challenges in the Arctic: Open water ▶     As the ice melts, fresh obstacles confront Arctic researchers.           COMMENT           Sustainability: A green Arctic ▶     Academic collaboration is essential for creating a sustainable future for Arctic development, says Lars Kullerud.             Governance: A peaceful Arctic ▶     Encourage dialogue between the producers and consumers of scientific knowledge in the north to keep the region conflict free, says Oran R. Young.             Arctic science: The local perspective ▶     Indigenous knowledge is maturing as a science, says Henry P. Huntington. But more work is needed to give the field the respect it deserves.             Books and Arts                   Bioethics: Brave new biopolitics ▶     Kevin Finneran hails a timely take on the debate raging over biotechnology breakthroughs in the United States.             Books in brief ▶             Anthropology: Centuries of skulls ▶     Alison Abbott enjoys a German exhibition charting how the human head is revered by cultures worldwide.             Q&A: Internet visionary ▶     As the new director of the Media Lab at the Massachusetts Institute of Technology (MIT) in Cambridge, Joichi Ito brings his knowledge of Internet start-ups — including Flickr, Twitter and licence provider Creative Commons — to the lab that developed the ideas behind the game Guitar Hero and Amazon Kindle's E-Ink technology. Ito talks about the value of playfulness and freedom in scientific discovery.             Correspondence                   Arctic warming: Sea-ice minimum is not a one-off Christian Melsheimer, Georg Heygster & Justus Notholt | Research investment: Vaccine research loses out Peter Hale, Simon Wain-Hobson & Robin A. Weiss | Military science: The JASONs bought into the Vietnam War Joseph Schwartz | Economics: Fallacy in costs of pollution control Neal Hockley           Corrections                   Correction ▶             Correction ▶                         Strands of life - 5 short films on physiology and medicine Recorded at the 2011 Meeting of Nobel Laureates, the films capture conversations between young researchers and Nobel prizewinning scientists. Watch the full series of films including this week's release "Hungry for knowledge" featuring Oliver Smithies. Supported by Mars, Incorporated and published weekly from Sept 15th - Oct 13th               Biological Sciences ▲top             RESEARCH           Latest Online                   Solutions for a cultivated planet ▶     Jonathan A. Foley, Navin Ramankutty, Kate A. Brauman, Emily S. Cassidy, James S. Gerber et al.     Increasing population and consumption are placing unprecedented demands on agric...             PDGF signalling controls age-dependent proliferation in pancreatic β-cells ▶     Hainan Chen, Xueying Gu, Yinghua Liu, Jing Wang, Stacey E. Wirt et al.     Determining the signalling pathways that direct tissue expansion is a principal ...             A high-resolution map of human evolutionary constraint using 29 mammals ▶     Kerstin Lindblad-Toh, Manuel Garber, Or Zuk, Michael F. Lin, Brian J. Parker et al.     The comparison of related genomes has emerged as a powerful lens for genome inte...             Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells ▶     Kosuke Yusa, S. Tamir Rashid, Helene Strick-Marchand, Ignacio Varela, Pei-Qi Liu et al.     Human induced pluripotent stem cells (iPSCs) represent a unique opportunity for ...             Perception of sniff phase in mouse olfaction ▶     Matthew Smear, Roman Shusterman, Rodney O’Connor, Thomas Bozza & Dmitry Rinberg     Olfactory systems encode odours by which neurons respond and by when they respon...             Genome sequencing reveals insights into physiology and longevity of the naked mole rat ▶     Eun Bae Kim, Xiaodong Fang, Alexey A. Fushan, Zhiyong Huang, Alexei V. Lobanov et al.     The naked mole rat (Heterocephalus glaber) is a strictly subterranean, extraordi...             A draft genome of Yersinia pestis from victims of the Black Death ▶     Kirsten I. Bos, Verena J. Schuenemann, G. Brian Golding, Hernán A. Burbano, Nicholas Waglechner et al.     Technological advances in DNA recovery and sequencing have drastically expanded ...             Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase ▶     Mardo Kõivomägi, Ervin Valk, Rainis Venta, Anna Iofik, Martin Lepiku et al.     Multisite phosphorylation of proteins has been proposed to transform a graded pr...             Distinct stem cells contribute to mammary gland development and maintenance ▶     Alexandra Van Keymeulen, Ana Sofia Rocha, Marielle Ousset, Benjamin Beck, Gaëlle Bouvencourt et al.     The mammary epithelium is composed of several cell lineages including luminal, a...             Feedback from rhodopsin controls rhodopsin exclusion in Drosophila photoreceptors ▶     Daniel Vasiliauskas, Esteban O. Mazzoni, Simon G. Sprecher, Konstantin Brodetskiy, Robert J. Johnston Jr et al.     Sensory systems with high discriminatory power use neurons that express only one...             Structural basis for the bifunctionality of fructose-1,6-bisphosphate aldolase/phosphatase ▶     Shinya Fushinobu, Hiroshi Nishimasu, Daiki Hattori, Hyun-Jin Song & Takayoshi Wakagi     Enzymes catalyse specific reactions and are essential for maintaining life. Alth...             Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase ▶     Juan Du, Rafael F. Say, Wei Lü, Georg Fuchs & Oliver Einsle     Fructose-1,6-bisphosphate (FBP) aldolase/phosphatase is a bifunctional, thermost...             Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis ▶     Yukiji Takeda, Sandra Costa, Estelle Delamarre, Carmen Roncal, Rodrigo Leite de Oliveira et al.     PHD2 serves as an oxygen sensor that rescues blood supply by regulating vessel f...             Articles and Letters                   An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor ▶     Christiane A. Opitz, Ulrike M. Litzenburger, Felix Sahm, Martina Ott, Isabel Tritschler et al.     Activation of the aryl hydrocarbon receptor (AHR) by environmental xenobiotic to...             Diffraction-unlimited all-optical imaging and writing with a photochromic GFP ▶     Tim Grotjohann, Ilaria Testa, Marcel Leutenegger, Hannes Bock, Nicolai T. Urban et al.     Lens-based optical microscopy failed to discern fluorescent features closer than...             DNA stretching by bacterial initiators promotes replication origin opening ▶     Karl E. Duderstadt, Kevin Chuang & James M. Berger     Many replication initiators form higher-order oligomers that process host replic...             Self-replication of information-bearing nanoscale patterns ▶     Tong Wang, Ruojie Sha, Rémi Dreyfus, Mirjam E. Leunissen, Corinna Maass et al.     DNA molecules provide what is probably the most iconic example of self-replicati...             Atmospheric oxygenation caused by a change in volcanic degassing pressure ▶     Fabrice Gaillard, Bruno Scaillet & Nicholas T. Arndt     The Precambrian history of our planet is marked by two major events: a pulse of ...             Strong contributors to network persistence are the most vulnerable to extinction ▶     Serguei Saavedra, Daniel B. Stouffer, Brian Uzzi & Jordi Bascompte     The architecture of mutualistic networks facilitates coexistence of individual p...             An olfactory receptor for food-derived odours promotes male courtship in Drosophila ▶     Yael Grosjean, Raphael Rytz, Jean-Pierre Farine, Liliane Abuin, Jérôme Cortot et al.     Many animals attract mating partners through the release of volatile sex pheromo...             Molecular organization of vomeronasal chemoreception ▶     Yoh Isogai, Sheng Si, Lorena Pont-Lezica, Taralyn Tan, Vikrant Kapoor et al.     The vomeronasal organ (VNO) has a key role in mediating the social and defensive...             Theta-paced flickering between place-cell maps in the hippocampus ▶     Karel Jezek, Espen J. Henriksen, Alessandro Treves, Edvard I. Moser & May-Britt Moser     The ability to recall discrete memories is thought to depend on the formation of...             Peripheral education of the immune system by colonic commensal microbiota ▶     Stephanie K. Lathrop, Seth M. Bloom, Sindhuja M. Rao, Katherine Nutsch, Chan-Wang Lio et al.     The instruction of the immune system to be tolerant of self, thereby preventing ...             A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable ▶     Hua Tian, Brian Biehs, Søren Warming, Kevin G. Leong, Linda Rangell et al.     The small intestine epithelium renews every 2 to 5 days, making it one of the mo...             Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A ▶     A. J. Ehrlicher, F. Nakamura, J. H. Hartwig, D. A. Weitz & T. P. Stossel     Mechanical stresses elicit cellular reactions mediated by chemical signals. Defe...             S-nitrosylation of NADPH oxidase regulates cell death in plant immunity ▶     Byung-Wook Yun, Angela Feechan, Minghui Yin, Noor B. B. Saidi, Thierry Le Bihan et al.     Changes in redox status are a conspicuous feature of immune responses in a variety...             Structure of human mitochondrial RNA polymerase ▶     Rieke Ringel, Marina Sologub, Yaroslav I. Morozov, Dmitry Litonin, Patrick Cramer et al.     Transcription of the mitochondrial genome is performed by a single-subunit RNA p...             News & Views                   Behavioural neuroscience: Fruity aphrodisiacs ▶     Benjamin Prud'homme & Nicolas Gompel             Cancer: Why tumours eat tryptophan ▶     George C. Prendergast             Brief Communications Arising                   InsP3R channel gating altered by clustering? ▶     Horia Vais, J. Kevin Foskett & Don-On Daniel Mak             Rahman et al. reply ▶     Taufiq Rahman, Alexander Skupin, Martin Falcke & Colin W. Taylor             Corrigenda                   Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration ▶     Aycan Sentürk, Sylvia Pfennig, Alexander Weiss, Katja Burk & Amparo Acker-Palmer             A plastidial sodium-dependent pyruvate transporter ▶     Tsuyoshi Furumoto, Teppei Yamaguchi, Yumiko Ohshima-Ichie, Masayoshi Nakamura, Yoshiko Tsuchida-Iwata et al.             Research Highlights                   Conservation biology: Culls won't save Tasmanian devils | Neurodegeneration: Parkinson's propagator | Climate-change ecology: Foreshadows of climates past | Evolution: These fins were made for walking | Microbiology: How a bacterium grabs the gut | Neurobiology: Stress alters brain connections         NEWS & COMMENT           More than teeth | Arctic science: The local perspective | Bioethics: Brave new biopolitics | Books in brief | Anthropology: Centuries of skulls | Research investment: Vaccine research loses out Peter Hale, Simon Wain-Hobson & Robin A. Weiss             More Biological Sciences ▶                         Watch the film! Microbe Hunters: The Science of Pathogen Detection Learn how researchers worldwide rely on Roche's 454 Sequencing Systems to provide fast and accurate detection of pathogens when speed-to-result matters most. For life science research use only. Not for use in diagnostic procedures.               Chemical Sciences ▲top             RESEARCH           Latest Online                   Genome sequencing reveals insights into physiology and longevity of the naked mole rat ▶     Eun Bae Kim, Xiaodong Fang, Alexey A. Fushan, Zhiyong Huang, Alexei V. Lobanov et al.     The naked mole rat (Heterocephalus glaber) is a strictly subterranean, extraordi...             Structural basis for the bifunctionality of fructose-1,6-bisphosphate aldolase/phosphatase ▶     Shinya Fushinobu, Hiroshi Nishimasu, Daiki Hattori, Hyun-Jin Song & Takayoshi Wakagi     Enzymes catalyse specific reactions and are essential for maintaining life. Alth...             Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase ▶     Juan Du, Rafael F. Say, Wei Lü, Georg Fuchs & Oliver Einsle     Fructose-1,6-bisphosphate (FBP) aldolase/phosphatase is a bifunctional, thermost...             Articles and Letters                   Self-replication of information-bearing nanoscale patterns ▶     Tong Wang, Ruojie Sha, Rémi Dreyfus, Mirjam E. Leunissen, Corinna Maass et al.     DNA molecules provide what is probably the most iconic example of self-replicati...             Atmospheric oxygenation caused by a change in volcanic degassing pressure ▶     Fabrice Gaillard, Bruno Scaillet & Nicholas T. Arndt     The Precambrian history of our planet is marked by two major events: a pulse of ...             S-nitrosylation of NADPH oxidase regulates cell death in plant immunity ▶     Byung-Wook Yun, Angela Feechan, Minghui Yin, Noor B. B. Saidi, Thierry Le Bihan     Changes in redox status are a conspicuous feature of immune responses in a variety...             Corrigendum                   A plastidial sodium-dependent pyruvate transporter ▶     Tsuyoshi Furumoto, Teppei Yamaguchi, Yumiko Ohshima-Ichie, Masayoshi Nakamura, Yoshiko Tsuchida-Iwata et al.           NEWS & COMMENT           An eye for success             More Chemical Sciences ▶               Physical Sciences ▲top             RESEARCH           Latest Online                   Efficient quantum computing using coherent photon conversion ▶     N. K. Langford, S. Ramelow, R. Prevedel, W. J. Munro, G. J. Milburn et al.     Single photons are excellent quantum information carriers: they were used in the...             Articles and Letters                   Diffraction-unlimited all-optical imaging and writing with a photochromic GFP ▶     Tim Grotjohann, Ilaria Testa, Marcel Leutenegger, Hannes Bock, Nicolai T. Urban et al.     Lens-based optical microscopy failed to discern fluorescent features closer than...             Low-Mach-number turbulence in interstellar gas revealed by radio polarization gradients ▶     B. M. Gaensler, M. Haverkorn, B. Burkhart, K. J. Newton–McGee, R. D. Ekers et al.     The interstellar medium of the Milky Way is multiphase, magnetized and turbulent...             Ocean-like water in the Jupiter-family comet 103P/Hartley 2 ▶     Paul Hartogh, Dariusz C. Lis, Dominique Bockelée-Morvan, Miguel de Val-Borro, Nicolas Biver et al.     For decades, the source of Earth's volatiles, especially water with a deuterium-...             Coherent coupling of a superconducting flux qubit to an electron spin ensemble in diamond ▶     Xiaobo Zhu, Shiro Saito, Alexander Kemp, Kosuke Kakuyanagi, Shin-ichi Karimoto et al.     During the past decade, research into superconducting quantum bits (qubits) base...             Theta-paced flickering between place-cell maps in the hippocampus ▶     Karel Jezek, Espen J. Henriksen, Alessandro Treves, Edvard I. Moser & May-Britt Moser     The ability to recall discrete memories is thought to depend on the formation of...             News & Views                   Applied physics: Controlled incandescence ▶     Jean-Jacques Greffet             Quantum engineering: Spins coupled to a persistent current ▶     Irinel Chiorescu             Research Highlights                   Nanotechnology: Sugar and shake sensor power | Climate-change ecology: Foreshadows of climates past | Optics: A mirage of invisibility         NEWS & COMMENT           The case of Dr Hicheur | An eye for success | Sustainability: A green Arctic | Q&A: Internet visionary | Arctic warming: Sea-ice minimum is not a one-off Christian Melsheimer, Georg Heygster & Justus Notholt             More Physical Sciences ▶               Earth & Environmental Sciences ▲top             RESEARCH           Latest Online                   Solutions for a cultivated planet ▶     Jonathan A. Foley, Navin Ramankutty, Kate A. Brauman, Emily S. Cassidy, James S. Gerber et al.     Increasing population and consumption are placing unprecedented demands on agric...             Articles and Letters                   Ocean-like water in the Jupiter-family comet 103P/Hartley 2 ▶     Paul Hartogh, Dariusz C. Lis, Dominique Bockelée-Morvan, Miguel de Val-Borro, Nicolas Biver et al.     For decades, the source of Earth's volatiles, especially water with a deuterium-...             Atmospheric oxygenation caused by a change in volcanic degassing pressure ▶     Fabrice Gaillard, Bruno Scaillet & Nicholas T. Arndt     The Precambrian history of our planet is marked by two major events: a pulse of ...             News & Views                   Earth science: Sea change for the rise of oxygen ▶     Timothy W. Lyons & Christopher T. Reinhard             Research Highlights                   Climate-change ecology: Foreshadows of climates past | Environmental science: Plastic from clothing hits shorelines         NEWS & COMMENT           Sustainability: A green Arctic | Arctic science: The local perspective | Arctic warming: Sea-ice minimum is not a one-off Christian Melsheimer, Georg Heygster & Justus Notholt | Economics: Fallacy in costs of pollution control Neal Hockley             More Earth & Environmental Sciences ▶               Specials - Nature Outlook: Medical Research MasterclassFree Access ▲top               Medical research masterclass ▶     Michelle Grayson             Lunchtime science ▶     Biophysicist at Yale University in New Haven, Connecticut. Shared 2009 Nobel Prize in Chemistry for knowledge of the structure and function of the ribosome — the intracellular machine that builds proteins from instructions carried by RNA. Born in Milwaukee, Wisconsin in 1940. The oldest of five children, Steitz has admitted to being an average student in high school, until motivated to compete against his youngest brother who was getting better grades. Steitz was a keen musician and chorister, and considered a career in music before finally choosing to pursue science.              On the wings of imagination ▶     Biochemist at Technion, the Israeli Institute of Technology in Haifa. Shared the 2004 Nobel Prize in Chemistry for the discovery of the ubiquitin system, which mediates protein degradation in all plant and animal cells by destroying proteins that are denatured, misfolded or no longer needed. Family moved from Poland in the 1920s, and he was born in Haifa in 1947. The following year the state of Israel was established.              Biochemistry without boundaries ▶     Biochemist at the University of Washington in Seattle, he won a share of the 1992 Nobel Prize in Physiology or Medicine for discoveries concerning reversible phosphorylation: a regulatory mechanism that activates and deactivates enzymes in the vast majority of living cells. Fischer was born in Shanghai, China, in 1920.              Tough science ▶     X-ray crystallographer currently at the Weizmann Institute of Science in Rehovot, Israel. She won a share of the 2009 Nobel Prize in Chemistry for her work on the structure and function of the ribosome. Yonath was born in 1939 in Jerusalem to a poor family. Her father died when she was 11 years old, and Yonath helped support her mother and younger sister. Yonath was the first Israeli woman to win a Nobel prize and the first woman in 45 years to win the Nobel Prize in Chemistry              Rational enthusiasm ▶     Chemist at the University of Strasbourg in France. Shared the 1987 Nobel Prize in Chemistry for development and use of molecules that recognize and interact with each other. Coined 'supramolecular chemistry', it is an area of chemistry that exploits non-covalent interactions. Born in 1939 in Rosheim in France, Lehn was the son of a baker who later became the city's organist. Music is Lehn's main passion other than science.              Heart of science ▶     Biochemist at the George Washington University in Washington, DC, he shared the 1998 Nobel Prize in Physiology or Medicine for the discovery that nitric oxide acts as a signalling molecule in the cardiovascular system, prompting blood vessels to relax. Murad was born in Whiting, Indiana in 1936. His American mother was only 17 years old when she eloped with his father, an Albanian immigrant. His parents ran a restaurant, where he and his two brothers worked. Murad used to memorize customers' orders and mentally tally their bills, which he believed trained his memory and maths skills.              Science addict ▶     Virologist at German Cancer Research Centre in Heidelberg. Joint winner of 2008 Nobel Prize in Physiology or Medicine for discovery of the role of human papillomavirus (HPV) in causing cervical cancer. zur Hausen was born in 1936 in Gelsenkirchen-Buer in Germany, an area that was heavily bombed during the Second World War.              Telomeres: All's well that ends well ▶     Elizabeth Blackburn gave the first lecture at the 2011 Lindau meeting, describing her Nobel prizewinning work on telomeres. These chromosomal caps are known to play a role in cancer and are implicated in ageing — but their full biological utility remains a mystery.              Translational research: The American way ▶     The United States publishes more biomedical research papers than ever before, yet drug development is stagnating. Several new initiatives aim to turn this knowledge into new remedies.              Masterclass: The gathering brainstorm ▶     In Lindau, a colloquy between a Nobel laureate and three students encouraged the young researchers to grapple with some of the biggest challenges in drug development.          Sponsors                     Visit Illumina at ASHG/ICHG - Booth #708 Stop by our booth for a demonstration of the new MiSeq™ personal sequencing system, and learn how our comprehensive portfolio of sequencing- and array-based solutions can help power your research. For a complete list of Illumina workshops, presentations, and events at the show, click here.               Careers & Jobs ▲top               Rookie review ▶     What the novice peer reviewer needs to know before combing through a submission.                   Postdocs probe industry ▶     Programme offers close-up view of industry opportunities.                   PhD funding inadequate ▶     Pay falls short of expenses for some European PhD candidates.                   Science careers unstable ▶     Survey uncovers frustrations with career uncertainties in the United Kingdom.                   Careers related news & comment                   Brazil cooks up transgenic bean | France toughens conflict rules | Redrawing the Arctic map: The new north | Q&A: Internet visionary             naturejobs.com Science jobs of the week       Postdoctoral Opportunity     International Agency for Research on Cancer Lyon, FR           Science Portfolio Adviser     Wellcome Trust London, GB           Faculty Positions     Memorial Sloan-Kettering Cancer Center New York, US           Junior Research Groups     University of Würzburg Würzburg, DE         No matter what your career stage, student, postdoc or senior scientist, you will find articles on naturejobs.com to help guide you in your science career. 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