Scientific Reports Biology Table of Contents e-alert: July 2011

01 August 2011      • Visit Scientific Reports • Submit your manuscript to Scientific Reports     Welcome to your Table of Contents e-alert for Scientific Reports           Biological Sciences               Population diversity and function of hyperpolarization-activated current in olfactory bulb mitral cells ▶     Kamilla Angelo, Troy W. Margrie     Although neurons are known to exhibit a broad array of intrinsic properties that impact critically on the computations they perform, very few studies have quantified such…             Hyperthermic seizures and aberrant cellular homeostasis in Drosophila dystrophic muscles ▶     April K. Marrone, Mariya M. Kucherenko, Robert Wiek et al.     In humans, mutations in the Dystrophin Glycoprotein Complex (DGC) cause muscular dystrophies (MDs) that are associated with muscle loss, seizures and brain abnormalities leading to…             Single-molecule sensing electrode embedded in-plane nanopore ▶     Makusu Tsutsui, Sakon Rahong, Yoko Iizumi et al.     Electrode-embedded nanopore is considered as a promising device structure for label-free single-molecule sequencing, the principle of which is based on nucleotide identification…             Triggered optical coherence tomography for capturing rapid periodic motion ▶     Ernest W. Chang, James B. Kobler, Seok H. Yun     Quantitative cross-sectional imaging of vocal folds during phonation is potentially useful for diagnosis and treatments of laryngeal disorders. Optical coherence tomography (OCT)…             The short-time structural plasticity of dendritic spines is altered in a model of Rett syndrome ▶     Silvia Landi, Elena Putignano, Elena Maria Boggio et al.     The maturation of excitatory transmission comes about through a developmental period in which dendritic spines are highly motile and their number, form and size are rapidly…             Commercial Teas Highlight Plant DNA Barcode Identification Successes and Obstacles ▶     Mark Y. Stoeckle, Catherine C. Gamble, Rohan Kirpekar et al.     Appearance does not easily identify the dried plant fragments used to prepare teas to species. Here we test recovery of standard DNA barcodes for land plants from a large array of …             Changes in the Adhesive Properties of Spider Aggregate Glue During the Evolution of Cobwebs ▶     Vasav Sahni, Todd A. Blackledge, Ali Dhinojwala     We compare the prey capture glues produced by orb-weaving spiders (viscid glue) and their evolutionary descendents, the cobweb-weaving spiders (gumfoot glue). These glues are…             Stability of domain structures in multi-domain proteins ▶     Ramachandra M. Bhaskara, Narayanaswamy Srinivasan     Multi-domain proteins have many advantages with respect to stability and folding inside cells. Here we attempt to understand the intricate relationship between the domain-domain…             Disruption of plasmepsin-4 and merozoites surface protein-7 genes in Plasmodium berghei induces combined virulence-attenuated phenotype ▶     Roberta Spaccapelo, Elena Aime, Sara Caterbi et al.     Blood stage malaria parasites causing a mild and self limited infection in mice have been obtained with either radiation or chemical mutagenesis showing the…             The Role of TSLP in IL-13-Induced Atopic March ▶     Zhou Zhu, Min-Hee Oh, Jinho Yu et al.     Although atopic dermatitis (AD) is the initial step of the "atopic march", a progression from AD to asthma, the underlying mechanism remains unknown. Selective expression of IL-13 …             Structural hierarchies define toughness and defect-tolerance despite simple and mechanically inferior brittle building blocks ▶     Dipanjan Sen, Markus J. Buehler     Mineralized biological materials such as bone, sea sponges or diatoms provide load-bearing and armor functions and universally feature structural hierarchies from nano to macro.…             Growing interfaces uncover universal fluctuations behind scale invariance ▶     Kazumasa A. Takeuchi, Masaki Sano, Tomohiro Sasamoto et al.     Stochastic motion of a point – known as Brownian motion – has many successful applications in science, thanks to its scale invariance and consequent universal features such as…             Label-free integrative pharmacology on-target of drugs at the β2-adrenergic receptor ▶     Ann M. Ferrie, Haiyan Sun, Ye Fang     We describe a label-free integrative pharmacology on-target (iPOT) method to assess the pharmacology of drugs at the β2-adrenergic receptor. This method combines dynamic mass…             Molecular evolution of HR, a gene that regulates the postnatal cycle of the hair follicle ▶     Amir Ali Abbasi     Hair is a unique mammalian trait that is absent in all other animal forms. Hairlessness is rare in mammals and humans are exceptional among primates in lacking dense layer of hair …             Model for in vivo progression of tumors based on co-evolving cell population and vasculature ▶     Sehyo C. Choe, Guannan Zhao, Zhenyuan Zhao et al.     With countless biological details emerging from cancer experiments, there is a growing need for minimal mathematical models which simultaneously advance our understanding of single…             Silicon uptake by sponges: a twist to understanding nutrient cycling on continental margins ▶     Manuel Maldonado, Laura Navarro, Ana Grasa et al.     About 75% of extant sponge species use dissolved silicon (DSi) to build a siliceous skeleton. We show that silicon (Si) uptake by sublittoral Axinella demosponges follows an…             Arabidopsis IRE1 catalyses unconventional splicing of bZIP60 mRNA to produce the active transcription factor ▶     Yukihiro Nagashima, Kei-ichiro Mishiba, Eiji Suzuki et al.     IRE1 plays an essential role in the endoplasmic reticulum (ER) stress response in yeast and mammals. We found that a double mutant of Arabidopsis IRE1A and IRE1B (ire1a/ire1b) is…             Non-specific binding of antibodies in immunohistochemistry: fallacies and facts ▶     Igor Buchwalow, Vera Samoilova, Werner Boecker et al.     The current protocols for blocking background staining in immunohistochemistry are based on conflicting reports. Background staining is thought to occur as a result of either…                 • Careers & Jobs           naturejobs.com Science jobs of the week       PhD in Biophysics / Cell Biology / Developmental Biology     Karlsruhe Institute of Technology (KIT)  Karlsruhe, Germany           Postdoctoral Associate     University of Florida - Department of Infectious Diseases & Pathology Gainesville, FL           Career Development Fellow     Medical Research Council Edinburgh, EH4 2XU, Britain           Research Associate in Epidemiology (Cohort Retention and Participation)     University of Bristol Bristol, United Kingdom           Post doc position in Molecular Virology, Biochemistry, Molecular Biology     Kansas University Medical Center Kansas, USA         No matter what your career stage, student, postdoc or senior scientist, you will find articles on naturejobs.com to help guide you in your science career. 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