The EDGE: Nature contents: 30 June 2011

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---THIS WEEK'S HIGHLIGHTS:

--Biological Sciences
-Morphological evolution caused by many subtle-effect substitutions
in regulatory DNA
Using the shavenbaby gene in the fruit fly Drosophila sechellia as a
model, the evolution of a hairless larva is shown to involve many
mutations of small effect, providing support for a 'gradualist'
evolutionary process.
http://links.ealert.nature.com/ctt?kn=100&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

--Physical Sciences
-A luminous quasar at a redshift of z = 7.085
Infrared deep-sky survey data are bringing ever more distant quasars
into view. The discovery of a luminous quasar with a redshift beyond
the previous high of z = 6.44 throws light on the ionization
state of the Universe as it was just 0.75 billion years after the Big Bang.
http://links.ealert.nature.com/ctt?kn=102&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

--Earth & Environmental Sciences
-A salt-water reservoir as the source of a compositionally stratified
plume on Enceladus
The first measurements of the composition of particles in the
emissions plume of Saturn's icy moon Enceladus point to an origin in
a subsurface salt-water reservoir.
http://links.ealert.nature.com/ctt?kn=97&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

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Nature Outlook: Biofuels

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--Podcast & Video
-This week, we tackle a plant plague and talk about higher education
as part of our Africa special. Plus, a new method that could make
gene therapy better.
http://links.ealert.nature.com/ctt?kn=131&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

--Special
-Africa
In this week's Africa special, a series of News, Feature and Comment
pieces takes a broad look at the current state of, and future prospects
for, science and technology in Africa.
http://links.ealert.nature.com/ctt?kn=109&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

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======================== NEWS AND COMMENT ========================
Read daily news coverage http://links.ealert.nature.com/ctt?kn=133&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

EDITORIALS
** Shot with its own gun
The Intergovernmental Panel on Climate Change must implement changes
now to regain lost credibility or it will remain an easy target for
critics seeking to score cheap points.
http://links.ealert.nature.com/ctt?kn=98&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Made in Japan
A new university on an island outpost looks set to succeed against
the odds.
http://links.ealert.nature.com/ctt?kn=107&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** A helping hand
What can individual researchers do for colleagues in Africa?
http://links.ealert.nature.com/ctt?kn=108&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

WORLD VIEW
** Give the new generation a chance
Romain Murenzi wants more young scientists in the developing world
to be given the same opportunity to build careers that he was.
http://links.ealert.nature.com/ctt?kn=14&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

SEVEN DAYS
** Seven days: 24-30 June 2011
The week in science
http://links.ealert.nature.com/ctt?kn=22&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

NEWS IN FOCUS
** Averting a swarm
Yemen's political instability may make it difficult to control locust
breeding.
http://links.ealert.nature.com/ctt?kn=21&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Stem-cell scientists grapple with clinics
In the absence of regulation, researchers weigh their options for
educating patients about unproven treatments.
http://links.ealert.nature.com/ctt?kn=20&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Call to curb lab tests on dogs
Canine remains the default option in outdated pharmaceutical toxicology.
http://links.ealert.nature.com/ctt?kn=30&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Biologist spared jail for grant fraud
A prompt confession and apparent remorse helped a former MIT researcher
to secure a lighter sentence.
http://links.ealert.nature.com/ctt?kn=29&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Okinawa goes recruiting
Research freedom proves trump card for interdisciplinary Japanese institute.
http://links.ealert.nature.com/ctt?kn=27&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

FEATURES
** Science in Africa: Lands of promise
Addressing a continent's challenges.
http://links.ealert.nature.com/ctt?kn=24&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Science in Africa: The view from the front line
Africa's nations are achieving some success in building their science
capacity, but the foundations remain unsteady.
http://links.ealert.nature.com/ctt?kn=34&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Science in Africa: Enter the dragon
China is pumping money into African science. But what do both sides
stand to gain — and lose?
http://links.ealert.nature.com/ctt?kn=32&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Agriculture: The wheat stalker
Scientists are fighting damaging wheat fungi from East Africa, but
breeding new crops won't help unless farmers plant them.
http://links.ealert.nature.com/ctt?kn=13&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

COMMENT
** Africa AIMS high
Eight years ago, physicist Neil Turok set up the African Institute for
Mathematical Sciences in South Africa. The initiative is now set to
expand across the continent.
http://links.ealert.nature.com/ctt?kn=103&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Research in a war zone
Bassirou Bonfoh and others offer lessons from a West African institute
that has survived ten years of conflict.
http://links.ealert.nature.com/ctt?kn=105&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Crowd control in Rwanda
Sub-Saharan Africa's most densely peopled mainland nation is determined
to head off a population crisis. Others should take note, say Josh
Ruxin and Antoinette Habinshuti.
http://links.ealert.nature.com/ctt?kn=95&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

BOOKS AND ARTS
** Stem cells: The clash of hype, hope and stem cells
A revealing book investigates the politicization of regenerative
medicine, finds Gilberto Corbellini.
http://links.ealert.nature.com/ctt?kn=79&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Climate change: Beyond Kyoto
Gwyn Prins commends the latest tome to advocate better ways to
accelerate decarbonization.
http://links.ealert.nature.com/ctt?kn=77&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=83&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** History: Holistic browsing
D. Graham Burnett muses on an exhibition exploring the legacy of
Stewart Brand's eco-handbook.
http://links.ealert.nature.com/ctt?kn=81&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

CORRESPONDENCE
** Block changes to Brazil's Forest Code
Luiz Antonio Martinelli
http://links.ealert.nature.com/ctt?kn=87&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** WHO working to be fit for purpose
Margaret Chan
http://links.ealert.nature.com/ctt?kn=85&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Population bomb: the UN responds
Hania Zlotnik
http://links.ealert.nature.com/ctt?kn=90&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** More at stake in stem-cell patents
David Albert Jones
http://links.ealert.nature.com/ctt?kn=89&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

OBITUARY
** Rosalyn Sussman Yalow (1921-2011)
The second woman to win the Nobel prize in medicine.
http://links.ealert.nature.com/ctt?kn=125&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

CORRIGENDA
** Imprints of fast-rotating massive stars in the Galactic Bulge
http://links.ealert.nature.com/ctt?kn=12&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Enterotypes of the human gut microbiome
http://links.ealert.nature.com/ctt?kn=39&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

======================== BIOLOGICAL SCIENCES ========================
RESEARCH
** Morphological evolution caused by many subtle-effect substitutions
in regulatory DNA
Nicolas Frankel, Deniz F. Erezyilmaz, Alistair P. McGregor, Shu Wang,
Francois Payre et al.
Morphology evolves often through changes in developmental genes, but
the causal...
http://links.ealert.nature.com/ctt?kn=100&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Genomic island variability facilitates Prochlorococcus-virus coexistence
Sarit Avrani, Omri Wurtzel, Itai Sharon, Rotem Sorek and Debbie Lindell
Prochlorococcus cyanobacteria are extremely abundant in the oceans,
as are the ...
http://links.ealert.nature.com/ctt?kn=122&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Integrated genomic analyses of ovarian carcinoma
(Participants are arranged by area of contribution and then by
institution.) Disease working group and tissue source sitesGenome
sequencing centres: Baylor College of MedicineBroad InstituteWashington
University in St Louis et al.
A catalogue of molecular aberrations that cause ovarian cancer is
critical for ...
http://links.ealert.nature.com/ctt?kn=120&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Modern optics in exceptionally preserved eyes of Early Cambrian
arthropods from Australia
Michael S. Y. Lee, James B. Jago, Diego C. Garcia-Bellido, Gregory D.
Edgecombe, James G. Gehling et al.
Despite the status of the eye as an "organ of extreme perfection"...
http://links.ealert.nature.com/ctt?kn=119&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** A gene regulatory network controlling the embryonic specification of
endoderm
Isabelle S. Peter and Eric H. Davidson
Specification of endoderm is the prerequisite for gut formation in
the embryoge...
http://links.ealert.nature.com/ctt?kn=118&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** De novo cardiomyocytes from within the activated adult heart after injury
Nicola Smart, Sveva Bollini, Karina N. Dube, Joaquim M. Vieira, Bin Zhou et al.
A significant bottleneck in cardiovascular regenerative medicine is the identif...
http://links.ealert.nature.com/ctt?kn=56&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Latent TGF-[bgr] binding protein 3 identifies a second heart field
in zebrafish
Yong Zhou, Timothy J. Cashman, Kathleen R. Nevis, Pablo Obregon, Sara
A. Carney et al.
The four-chambered mammalian heart develops from two fields of cardiac
progenit...
http://links.ealert.nature.com/ctt?kn=47&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** MicroRNAs 103 and 107 regulate insulin sensitivity
Mirko Trajkovski, Jean Hausser, Jurgen Soutschek, Bal Bhat, Akinc
Akin et al.
Defects in insulin signalling are among the most common and earliest
defects th...
http://links.ealert.nature.com/ctt?kn=48&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction
factor counteracted by Vpx
Nadine Laguette, Bijan Sobhian, Nicoletta Casartelli, Mathieu Ringeard,
Christine Chable-Bessia et al.
The primate lentivirus auxiliary protein Vpx counteracts an unknown
restriction...
http://links.ealert.nature.com/ctt?kn=41&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Vpx relieves inhibition of HIV-1 infection of macrophages mediated
by the SAMHD1 protein
Kasia Hrecka, Caili Hao, Magda Gierszewska, Selene K. Swanson,
Malgorzata Kesik-Brodacka et al.
Macrophages and dendritic cells have key roles in viral infections,
providing v...
http://links.ealert.nature.com/ctt?kn=43&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Single-molecule fluorescence reveals sequence-specific misfolding
in multidomain proteins
Madeleine B. Borgia, Alessandro Borgia, Robert B. Best, Annette Steward,
Daniel Nettels et al.
A large range of debilitating medical conditions is linked to protein
misfoldin...
http://links.ealert.nature.com/ctt?kn=44&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Crystal structure of a copper-transporting PIB-type ATPase
Pontus Gourdon, Xiang-Yu Liu, Tina Skjorringe, J. Preben Morth, Lisbeth
Birk Moller et al.
Heavy-metal homeostasis and detoxification is crucial for cell viability.
P-typ...
http://links.ealert.nature.com/ctt?kn=126&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Excitatory transmission from the amygdala to nucleus accumbens
facilitates reward seeking
Garret D. Stuber, Dennis R. Sparta, Alice M. Stamatakis, Wieke A. van
Leeuwen, Juanita E. Hardjoprajitno et al.
The basolateral amygdala (BLA) has a crucial role in emotional learning
irrespe...
http://links.ealert.nature.com/ctt?kn=104&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** A role for glia in the progression of Rett's syndrome
Daniel T. Lioy, Saurabh K. Garg, Caitlin E. Monaghan, Jacob Raber,
Kevin D. Foust et al.
Rett's syndrome (RTT) is an X-chromosome-linked autism spectrum disorde...
http://links.ealert.nature.com/ctt?kn=117&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Direct conversion of mouse fibroblasts to hepatocyte-like cells by
defined factors
Sayaka Sekiya and Atsushi Suzuki
The location and timing of cellular differentiation must be stringently
control...
http://links.ealert.nature.com/ctt?kn=114&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** In vivo genome editing restores haemostasis in a mouse model of haemophilia
Hojun Li, Virginia Haurigot, Yannick Doyon, Tianjian Li, Sunnie Y. Wong et al.
Editing of the human genome to correct disease-causing mutations is a promising...
http://links.ealert.nature.com/ctt?kn=112&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Functional mapping of single spines in cortical neurons in vivo
Xiaowei Chen, Ulrich Leischner, Nathalie L. Rochefort, Israel Nelken
and Arthur Konnerth
The individual functional properties and spatial arrangement of
afferent synapt...
http://links.ealert.nature.com/ctt?kn=110&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Enterotypes of the human gut microbiome
Manimozhiyan Arumugam, Jeroen Raes, Eric Pelletier, Denis Le Paslier,
Takuji Yamada et al.
http://links.ealert.nature.com/ctt?kn=39&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Microbiology: Arms race in a drop of sea water
Frederic Partensky and Laurence Garczarek
Marine cyanobacteria can shrug off viral assault by inactivating the
genes involved in virus attachment. But this strategy has a cost: it
may affect cell fitness or even favour infection by other viruses.
http://links.ealert.nature.com/ctt?kn=46&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Regenerative medicine: Muscle for a damaged heart
Vincent Christoffels
When cardiac muscle cells die during a heart attack, this can lead to
heart failure and even death. It now emerges that stem cells of the
'sheet' enveloping the heart can be coaxed to form new muscle after
such an event.
http://links.ealert.nature.com/ctt?kn=37&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** HIV: Going for the watchman
Efrem S. Lim and Michael Emerman
A protein called SAMHD1 seems to hinder the infection of key cells
of the immune system by HIV-1. Cousins of this virus, however, produce
a factor that overcomes the protective effects of SAMHD1.
http://links.ealert.nature.com/ctt?kn=38&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

NEWS & COMMENT
** Palaeontology: Worldly dinosaurs roamed afar
http://links.ealert.nature.com/ctt?kn=40&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Biology: Algal synchronized swimming
http://links.ealert.nature.com/ctt?kn=68&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Molecular neuroscience: Can humans sense magnetic fields?
http://links.ealert.nature.com/ctt?kn=66&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Phylogenetics: True origin of true crocodiles
http://links.ealert.nature.com/ctt?kn=67&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Bioengineering: RNA scaffolds boost biosynthesis
http://links.ealert.nature.com/ctt?kn=64&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Ecology: Scat evidence exonerates wolves
http://links.ealert.nature.com/ctt?kn=65&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Neuroscience: How experience shapes the brain
http://links.ealert.nature.com/ctt?kn=62&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Stem cells: The clash of hype, hope and stem cells
A revealing book investigates the politicization of regenerative
medicine, finds Gilberto Corbellini.
http://links.ealert.nature.com/ctt?kn=79&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=83&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** WHO working to be fit for purpose
Margaret Chan
http://links.ealert.nature.com/ctt?kn=85&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Population bomb: the UN responds
Hania Zlotnik
http://links.ealert.nature.com/ctt?kn=90&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** More at stake in stem-cell patents
David Albert Jones
http://links.ealert.nature.com/ctt?kn=89&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Rosalyn Sussman Yalow (1921-2011)
The second woman to win the Nobel prize in medicine.
http://links.ealert.nature.com/ctt?kn=125&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** More News & Comment on BIOLOGICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=72&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

=========================== ADVERTISEMENT ===========================

Eppendorf Award for Young European Investigators

Nature is the partner for the Eppendorf Award for Young European
Investigators. This year's prize was awarded to Assistant Professor
Suzan Rooijakkers, PhD, for her discoveries of how the pathogen
Staphylococcus aureus evades immune attack to survive in the human host.

Listen to a podcast from the award ceremony.
http://links.ealert.nature.com/ctt?kn=19&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

=====================================================================

======================== CHEMICAL SCIENCES ========================
RESEARCH
** Vpx relieves inhibition of HIV-1 infection of macrophages mediated
by the SAMHD1 protein
Kasia Hrecka, Caili Hao, Magda Gierszewska, Selene K. Swanson,
Malgorzata Kesik-Brodacka et al.
Macrophages and dendritic cells have key roles in viral infections,
providing v...
http://links.ealert.nature.com/ctt?kn=43&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Crystal structure of a copper-transporting PIB-type ATPase
Pontus Gourdon, Xiang-Yu Liu, Tina Skjorringe, J. Preben Morth,
Lisbeth Birk Moller et al.
Heavy-metal homeostasis and detoxification is crucial for cell
viability. P-typ...
http://links.ealert.nature.com/ctt?kn=126&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Molecular physics: Matter-wave interference made clear
Uwe Becker
Interference patterns are generated when light from a point source
passes through two parallel slits. Electrons emitted from diatomic
molecules produce analogous patterns, but these couldn't be observed
directly - until now.
http://links.ealert.nature.com/ctt?kn=63&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** HIV: Going for the watchman
Efrem S. Lim and Michael Emerman
A protein called SAMHD1 seems to hinder the infection of key cells of
the immune system by HIV-1. Cousins of this virus, however, produce a
factor that overcomes the protective effects of SAMHD1.
http://links.ealert.nature.com/ctt?kn=38&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** More News & Comment on CHEMICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=45&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

======================== PHYSICAL SCIENCES ========================
RESEARCH
** A luminous quasar at a redshift of z = 7.085
Daniel J. Mortlock, Stephen J. Warren, Bram P. Venemans, Mitesh Patel,
Paul C. Hewett et al.
The intergalactic medium was not completely reionized until
approximately a bil...
http://links.ealert.nature.com/ctt?kn=102&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** A salt-water reservoir as the source of a compositionally
stratified plume on Enceladus
F. Postberg, J. Schmidt, J. Hillier, S. Kempf and R. Srama
The discovery of a plume of water vapour and ice particles emerging
from warm f...
http://links.ealert.nature.com/ctt?kn=97&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Observation of squeezed light from one atom excited with two photons
A. Ourjoumtsev, A. Kubanek, M. Koch, C. Sames, P. W. H. Pinkse et al.
Single quantum emitters such as atoms are well known as non-classical
light sou...
http://links.ealert.nature.com/ctt?kn=61&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Quantum quench of Kondo correlations in optical absorption
C. Latta, F. Haupt, M. Hanl, A. Weichselbaum, M. Claassen et al.
The interaction between a single confined spin and the spins of an
electron res...
http://links.ealert.nature.com/ctt?kn=57&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Thermal spin current from a ferromagnet to silicon by Seebeck
spin tunnelling
Jean-Christophe Le Breton, Sandeep Sharma, Hidekazu Saito, Shinji
Yuasa and Ron Jansen
Heat generation by electric current, which is ubiquitous in electronic
devices ...
http://links.ealert.nature.com/ctt?kn=60&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Giant boid snake from the Paleocene neotropics reveals hotter past
equatorial temperatures
Jason J. Head, Jonathan I. Bloch, Alexander K. Hastings, Jason R.
Bourque, Edwin A. Cadena et al.
http://links.ealert.nature.com/ctt?kn=1&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Imprints of fast-rotating massive stars in the Galactic Bulge
Cristina Chiappini, Urs Frischknecht, Georges Meynet, Raphael Hirschi,
Beatriz Barbuy et al.
http://links.ealert.nature.com/ctt?kn=12&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Cosmology: A monster in the early Universe
Chris Willott
The most distant quasar yet discovered sets constraints on the formation
mechanism of black holes. Its light spectrum has tantalizing features
that are expected to be observed before the reionization epoch ended.
http://links.ealert.nature.com/ctt?kn=10&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Quantum optics: Atom gives light a subtle squeeze
H. J. Carmichael and L. A. Orozco
When it comes to measuring physical quantities, the more that quantum
uncertainties can be squeezed the better. But when just one atom is
involved, demonstrating less squeezing is the real challenge.
http://links.ealert.nature.com/ctt?kn=11&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Molecular physics: Matter-wave interference made clear
Uwe Becker
Interference patterns are generated when light from a point source passes
through two parallel slits. Electrons emitted from diatomic molecules
produce analogous patterns, but these couldn't be observed directly -
until now.
http://links.ealert.nature.com/ctt?kn=63&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Atomic physics and quantum optics using superconducting circuits
J. Q. You and Franco Nori
Superconducting circuits based on Josephson junctions exhibit macroscopic
quant...
http://links.ealert.nature.com/ctt?kn=9&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

NEWS & COMMENT
** Technology: A jump on wireless power
http://links.ealert.nature.com/ctt?kn=2&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Climate change: Storms shift with climate change
http://links.ealert.nature.com/ctt?kn=4&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Shot with its own gun
The Intergovernmental Panel on Climate Change must implement changes
now to regain lost credibility or it will remain an easy target for
critics seeking to score cheap points.
http://links.ealert.nature.com/ctt?kn=98&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=83&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Block changes to Brazil's Forest Code
Luiz Antonio Martinelli
http://links.ealert.nature.com/ctt?kn=87&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** More News & Comment on PHYSICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=55&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

======================== EARTH AND ENVIRONMENTAL SCIENCES ========================
RESEARCH
** A salt-water reservoir as the source of a compositionally stratified
plume on Enceladus
F. Postberg, J. Schmidt, J. Hillier, S. Kempf and R. Srama
The discovery of a plume of water vapour and ice particles emerging
from warm f...
http://links.ealert.nature.com/ctt?kn=97&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

NEWS & COMMENT
** Climate change: Storms shift with climate change
http://links.ealert.nature.com/ctt?kn=4&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Oceanography: Ocean levels climbing faster
http://links.ealert.nature.com/ctt?kn=5&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Climate change: Beyond Kyoto
Gwyn Prins commends the latest tome to advocate better ways to accelerate
decarbonization.
http://links.ealert.nature.com/ctt?kn=77&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=83&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** History: Holistic browsing
D. Graham Burnett muses on an exhibition exploring the legacy of Stewart
Brand's eco-handbook.
http://links.ealert.nature.com/ctt?kn=81&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** Block changes to Brazil's Forest Code
Luiz Antonio Martinelli
http://links.ealert.nature.com/ctt?kn=87&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

** More News & Comment on EARTH AND ENVIRONMENTAL SCIENCES
http://links.ealert.nature.com/ctt?kn=54&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

=========================== ADVERTISEMENT ===========================

Nature Reviews Immunology
FOCUS ON METABOLISM AND IMMUNOLOGY
http://links.ealert.nature.com/ctt?kn=26&ms=MzY3Njg2NDUS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTA1MTE3MDY5S0&mt=1&rt=0

Articles in this Focus explore the interplay between metabolism and
the immune system, explaining how inflammation drives type 2 diabetes,
how fat tissue mediators affect inflammation and metabolic disease,
and how T cell metabolism is linked to T cell fate.

Access is FREE until August 2011

The EDGE

Wednesday, June 29, 2011

Nature contents: 30 June 2011

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