The EDGE: Nature contents: 09 June 2011

Nature Alert
The science that matters. Every week.

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View Table of Contents http://links.ealert.nature.com/ctt?kn=64&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

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=========================== ADVERTISEMENT ===========================

---THIS WEEK'S HIGHLIGHTS:

--Biological Sciences
-Hepatitis C
More people are infected with Hepatitis C virus (HCV) than HIV yet
it is a neglected epidemic. Diagnosis and treatment are arduous, and
there is no vaccine. However, new drugs that improve HCV treatment
could herald an era of HCV awareness.
http://links.ealert.nature.com/ctt?kn=151&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

--Physical Sciences
-Direct measurement of the quantum wavefunction
The wavefunction, simultaneously describing the wave- and particle-
like nature of matter, is central to quantum theory. Following this
experiment, though, the very nature of the wavefunction becomes a
subject of debate.
http://links.ealert.nature.com/ctt?kn=112&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

--Earth & Environmental Sciences
-Irregular tropical glacier retreat over the Holocene epoch driven
by progressive warming
The Telata glacier, high in the Bolivian Andes, provides a 11,000-year
history of tropical glacier fluctuation: it records a dramatic reduction
in glacier size during the past 200 years, and models predict a 4º-5ºC
warming in the tropical Andes by 2100.
http://links.ealert.nature.com/ctt?kn=114&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

=========================== ADVERTISEMENT ===========================

Nature Publishing Index China 2010 NEW!

Nature Publishing Group is delighted to present the inaugural edition
of the Nature Publishing Index 2010 China. The Nature Publishing Index
2010 China reports the rankings of research institutions and cities in
mainland China and Hong Kong based on their output of research articles
in Nature journals and points to where some of best research is being
conducted in China.

View the China rankings now!
http://links.ealert.nature.com/ctt?kn=120&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

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--Podcast & Video
-In this week's podcast: cyber warfare, species xenophobia and the
chemistry of water. Plus, the best of the rest from this week's Nature.
http://links.ealert.nature.com/ctt?kn=142&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

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======================== NEWS AND COMMENT ========================
Read daily news coverage http://links.ealert.nature.com/ctt?kn=143&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

EDITORIALS
** Cyberwarfare challenge
National cybersecurity plans should go beyond the cold-war mentality
of an arms race and focus more on linking traditional computer security
with protections for industrial control systems.
http://links.ealert.nature.com/ctt?kn=109&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Second chances
Leaders must end a run of unmet pledges when they meet to discuss sustainable development.
http://links.ealert.nature.com/ctt?kn=110&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Misspent energy
The crisis at Fukushima Daiichi should spark a rethink of nuclear-
research programmes.
http://links.ealert.nature.com/ctt?kn=119&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

WORLD VIEW
** Beware of gifts that come at too great a cost
Danger lurks for state universities when philanthropy encroaches on
academic independence, warns Sheldon Krimsky.
http://links.ealert.nature.com/ctt?kn=23&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

SEVEN DAYS
** Seven days: 3-9 June 2011
The week in science
http://links.ealert.nature.com/ctt?kn=31&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

NEWS IN FOCUS
** Fukushima deep in hot water
Rising levels of radioactive liquid hamper clean-up effort.
http://links.ealert.nature.com/ctt?kn=29&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** A healthier Japan
Yusuke Nakamura, a geneticist at the University of Tokyo, has long
argued that the country should reform its health-care system and work
harder to cash in on its biological discoveries. His mission was given
fresh urgency by the Tohoku earthquake and tsunami in March — and now
he has a pulpit. In January, Nakamura launched the Office of Medical
Innovation, a cabinet-level advisory organization, and he will make
his case at a high-level government meeting next week.
http://links.ealert.nature.com/ctt?kn=28&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Microbe outbreak panics Europe
Spread of rare Escherichia coli strain raises questions over surveillance
of infectious diseases.
http://links.ealert.nature.com/ctt?kn=37&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** US research facilities anticipate budget gloom
Interdisciplinary centres are at the sharp end of proposed cuts.
http://links.ealert.nature.com/ctt?kn=36&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Hungarian natural history under threat
Historical collections given marching orders as government plans
military university at museum site.
http://links.ealert.nature.com/ctt?kn=34&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Whistle-blower claims his accusations cost him his job
University denies it retaliated against researcher who questioned
supervisor's data.
http://links.ealert.nature.com/ctt?kn=32&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

FEATURES
** Computer security: Is this the start of cyberwarfare?
Last year's Stuxnet virus attack represented a new kind of threat to
critical infrastructure
http://links.ealert.nature.com/ctt?kn=15&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Evolution: Darwin's city
David Sloan Wilson is using the lens of evolution to understand
life in the struggling city of Binghamton, New York. Next, he
wants to improve it.
http://links.ealert.nature.com/ctt?kn=13&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

COMMENT
** Save our soils
Researchers must collaborate to manage one of the planet's most precious
and threatened resources - for food production and much more, says
Steve Banwart.
http://links.ealert.nature.com/ctt?kn=121&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Don't judge species on their origins
Conservationists should assess organisms on environmental impact rather
than on whether they are natives, argue Mark Davis and 18 other ecologists.
http://links.ealert.nature.com/ctt?kn=115&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

BOOKS AND ARTS
** Ethics: Battling the body brokers
A hard-hitting book calls for greater transparency to deter the illegal
trade in human blood, organs and eggs, finds Laura Spinney.
http://links.ealert.nature.com/ctt?kn=117&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=107&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Evolution: Darwin's other books
From geology to mould, the naturalist's publications form a coherent
whole, finds Eugenie Scott.
http://links.ealert.nature.com/ctt?kn=91&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Q&A: The machinist
Dutch artist Christiaan Zwanikken makes computer-controlled mechanical
sculptures, many of which use animal skeletons he has found. As a film
about Zwanikken's work and life at an isolated Portuguese convent
premieres in Edinburgh, UK, he discusses human relationships with other
animals and machines.
http://links.ealert.nature.com/ctt?kn=89&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

CORRESPONDENCE
** EU innovation must benefit society
Sybille van den Hove, Jacqueline McGlade and Michael H. Depledge
http://links.ealert.nature.com/ctt?kn=95&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** NIH: translation centre bridges a gap
John C. Reed and E. Lucile White
http://links.ealert.nature.com/ctt?kn=93&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** NIH: FDA key for speed and safety
James P. Reichmann
http://links.ealert.nature.com/ctt?kn=99&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Slovenian scientists reward mentors
Anze Zupanic
http://links.ealert.nature.com/ctt?kn=97&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

ERRATUM
** Eutherian mammals use diverse strategies to initiate X-chromosome
inactivation during development
http://links.ealert.nature.com/ctt?kn=57&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

=========================== ADVERTISEMENT ===========================

The New York Stem Cell Foundation
requests applications from early career investigators in the US,
Canada and the UK to cultivate innovative projects exploring fundamental
areas of developmental, cellular, cognitive, and behavioral
neuroscience. Proposals need not be related to stem cells. The
award provides $1.5M USD over 5 years. Closing date July 8, 2011.

http://links.ealert.nature.com/ctt?kn=136&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

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======================== BIOLOGICAL SCIENCES ========================
RESEARCH
** Role of the ubiquitin-like protein Hub1 in splice-site usage and
alternative splicing
Shravan Kumar Mishra, Tim Ammon, Grzegorz M. Popowicz, Marcin Krajewski,
Roland J. Nagel et al.
Alternative splicing of pre-messenger RNAs diversifies gene products
in eukaryo...
http://links.ealert.nature.com/ctt?kn=116&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Role of YAP/TAZ in mechanotransduction
Sirio Dupont, Leonardo Morsut, Mariaceleste Aragona, Elena Enzo,
Stefano Giulitti et al.
Cells perceive their microenvironment not only through soluble
signals but also...
http://links.ealert.nature.com/ctt?kn=126&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Discovery of novel intermediate forms redefines the fungal tree
of life
Meredith D. M. Jones, Irene Forn, Catarina Gadelha, Martin J. Egan,
David Bass et al.
Fungi are the principal degraders of biomass in terrestrial ecosystems
and esta...
http://links.ealert.nature.com/ctt?kn=124&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Visual place learning in Drosophila melanogaster
Tyler A. Ofstad, Charles S. Zuker and Michael B. Reiser
The ability of insects to learn and navigate to specific locations
in the envir...
http://links.ealert.nature.com/ctt?kn=123&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** A genetically humanized mouse model for hepatitis C virus infection
Marcus Dorner, Joshua A. Horwitz, Justin B. Robbins, Walter T.
Barry, Qian Feng et al.
Hepatitis C virus (HCV) remains a major medical problem. Antiviral
treatment is...
http://links.ealert.nature.com/ctt?kn=122&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Immunogenicity of induced pluripotent stem cells
Tongbiao Zhao, Zhen-Ning Zhang, Zhili Rong and Yang Xu
Induced pluripotent stem cells (iPSCs), reprogrammed from somatic
cells with de...
http://links.ealert.nature.com/ctt?kn=131&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** In vivo imaging of Treg cells providing immune privilege to
the haematopoietic stem-cell niche
Joji Fujisaki, Juwell Wu, Alicia L. Carlson, Lev Silberstein,
Prabhakar Putheti et al.
Stem cells reside in a specialized regulatory microenvironment
or niche, where ...
http://links.ealert.nature.com/ctt?kn=129&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** A somitic Wnt16/Notch pathway specifies haematopoietic stem
cells
Wilson K. Clements, Albert D. Kim, Karen G. Ong, John C. Moore,
Nathan D. Lawson et al.
Haematopoietic stem cells (HSCs) are a self-renewing population
of cells that c...
http://links.ealert.nature.com/ctt?kn=128&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Direct reprogramming of somatic cells is promoted by maternal
transcription factor Glis1
Momoko Maekawa, Kei Yamaguchi, Tomonori Nakamura, Ran Shibukawa,
Ikumi Kodanaka et al.
Induced pluripotent stem cells (iPSCs) are generated from somatic
cells by the ...
http://links.ealert.nature.com/ctt?kn=127&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** A function for cyclin D1 in DNA repair uncovered by protein interactome
analyses in human cancers
Siwanon Jirawatnotai, Yiduo Hu, Wojciech Michowski, Joshua E. Elias,
Lisa Becks et al.
Cyclin D1 is a component of the core cell cycle machinery. Abnormally
high leve...
http://links.ealert.nature.com/ctt?kn=68&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Structure and function of a membrane component SecDF that enhances
protein export
Tomoya Tsukazaki, Hiroyuki Mori, Yuka Echizen, Ryuichiro Ishitani,
Shuya Fukai et al.
Protein translocation across the bacterial membrane, mediated by
the secretory ...
http://links.ealert.nature.com/ctt?kn=58&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** MicroRNAs 103 and 107 regulate insulin sensitivity
Mirko Trajkovski, Jean Hausser, Jurgen Soutschek, Bal Bhat, Akinc
Akin et al.
Defects in insulin signalling are among the most common and earliest
defects th...
http://links.ealert.nature.com/ctt?kn=102&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** CCL2 recruits inflammatory monocytes to facilitate breast-tumour
metastasis
Bin-Zhi Qian, Jiufeng Li, Hui Zhang, Takanori Kitamura, Jinghang
Zhang et al.
Macrophages, which are abundant in the tumour microenvironment,
enhance maligna...
http://links.ealert.nature.com/ctt?kn=101&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** De novo cardiomyocytes from within the activated adult heart after
injury
Nicola Smart, Sveva Bollini, Karina N. Dube, Joaquim M. Vieira, Bin
Zhou et al.
A significant bottleneck in cardiovascular regenerative medicine is
the identif...
http://links.ealert.nature.com/ctt?kn=134&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Whole-genome sequencing identifies recurrent mutations in chronic
lymphocytic leukaemia
Xose S. Puente, Magda Pinyol, Victor Quesada, Laura Conde, Gonzalo R.
Ordonez et al.
Chronic lymphocytic leukaemia (CLL), the most frequent leukaemia in
adults in W...
http://links.ealert.nature.com/ctt?kn=135&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Eutherian mammals use diverse strategies to initiate X-chromosome
inactivation during development
Ikuhiro Okamoto, Catherine Patrat, Dominique Thepot, Nathalie Peynot,
Patricia Fauque et al.
http://links.ealert.nature.com/ctt?kn=57&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Stem cells: iPS cells under attack
Effie Apostolou and Konrad Hochedlinger
Induced pluripotent stem cells offer promise for patient-specific
regenerative therapy. But a study now cautions that, even when
immunologically matched, these cells can be rejected after transplantation.
http://links.ealert.nature.com/ctt?kn=60&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Epidemiology: How common is autism?
Catherine Lord
Autism spectrum disorders vary greatly in severity. By including
children in regular education who received no special help, an
epidemiological study has found these disorders to be up to three
times more prevalent than thought.
http://links.ealert.nature.com/ctt?kn=52&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Neuroscience: Flies race to a safe place
Troy Zars
Is the fruitfly one of the animals that use visual cues to guide
navigation and spatial learning? And if so, how does the simple fly
brain support spatial memory formation? Some answers are now emerging.
http://links.ealert.nature.com/ctt?kn=54&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** DNA repair: Cyclin D1 multitasks
Jiri Bartek and Jiri Lukas
Cyclin D1 is one of the drivers of the cell cycle, and its deregulation
may promote the development of tumours. Surprisingly, this protein also
mediates the repair of damaged DNA, a mechanism that commonly prevents
cancer.
http://links.ealert.nature.com/ctt?kn=55&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

NEWS & COMMENT
** Anthropology: Dinner date in Madagascar
http://links.ealert.nature.com/ctt?kn=48&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Cancer: Probing for pancreatic cancer
http://links.ealert.nature.com/ctt?kn=49&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Immunology: Cells sense house dust
http://links.ealert.nature.com/ctt?kn=50&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Evolutionary biology: Stinky, stocky and stripy for a reason
http://links.ealert.nature.com/ctt?kn=51&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Cancer: How cancer cells survive stress
http://links.ealert.nature.com/ctt?kn=80&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Save our soils
Researchers must collaborate to manage one of the planet's most
precious and threatened resources - for food production and
much more, says Steve Banwart.
http://links.ealert.nature.com/ctt?kn=121&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Ethics: Battling the body brokers
A hard-hitting book calls for greater transparency to deter the illegal
trade in human blood, organs and eggs, finds Laura Spinney.
http://links.ealert.nature.com/ctt?kn=117&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=107&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** EU innovation must benefit society
Sybille van den Hove, Jacqueline McGlade and Michael H. Depledge
http://links.ealert.nature.com/ctt?kn=95&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** NIH: translation centre bridges a gap
John C. Reed and E. Lucile White
http://links.ealert.nature.com/ctt?kn=93&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** NIH: FDA key for speed and safety
James P. Reichmann
http://links.ealert.nature.com/ctt?kn=99&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

CAREERS
** Biomedical research: Growing with the flow
http://links.ealert.nature.com/ctt?kn=78&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** More News & Comment on BIOLOGICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=84&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

=========================== ADVERTISEMENT ===========================

Nature Outlook: Hepatitis C

For the first time in decades, new drugs are about to be launched that
could substantially improve treatment and herald a new era of HCV awareness.
Access the Outlook free online for six months.
http://links.ealert.nature.com/ctt?kn=21&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0 .

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=====================================================================

======================== CHEMICAL SCIENCES ========================
RESEARCH
** Role of the ubiquitin-like protein Hub1 in splice-site usage and
alternative splicing
Shravan Kumar Mishra, Tim Ammon, Grzegorz M. Popowicz, Marcin Krajewski,
Roland J. Nagel et al.
Alternative splicing of pre-messenger RNAs diversifies gene products in
eukaryo...
http://links.ealert.nature.com/ctt?kn=116&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Direct measurement of the quantum wavefunction
Jeff S. Lundeen, Brandon Sutherland, Aabid Patel, Corey Stewart and
Charles Bamber
The wavefunction is the complex distribution used to completely describe
a quan...
http://links.ealert.nature.com/ctt?kn=79&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Hydrogen bonding at the water surface revealed by isotopic dilution
spectroscopy
Igor V. Stiopkin, Champika Weeraman, Piotr A. Pieniazek, Fadel Y.
Shalhout, James L. Skinner et al.
The air-water interface is perhaps the most common liquid interface. It...
http://links.ealert.nature.com/ctt?kn=76&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Structure and function of a membrane component SecDF that enhances
protein export
Tomoya Tsukazaki, Hiroyuki Mori, Yuka Echizen, Ryuichiro Ishitani,
Shuya Fukai et al.
Protein translocation across the bacterial membrane, mediated by the
secretory ...
http://links.ealert.nature.com/ctt?kn=58&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Physical chemistry: Water's wafer-thin surface
Pavel Jungwirth
A combination of vibrational spectroscopy and molecular calculations
reveals that only the surface layer of water at the interface with
air has a distinctly different structure from the bulk liquid.
http://links.ealert.nature.com/ctt?kn=77&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Quantum physics: How to catch a wave
Onur Hosten
The wavefunction is a central mathematical entity in quantum physics. It
is used to completely describe the state of a system. A means of probing
it directly is now on hand.
http://links.ealert.nature.com/ctt?kn=74&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** More News & Comment on CHEMICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=56&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

======================== PHYSICAL SCIENCES ========================
RESEARCH
** A current filamentation mechanism for breaking magnetic field lines
during reconnection
H. Che, J. F. Drake and M. Swisdak
During magnetic reconnection, the field lines must break and reconnect
to relea...
http://links.ealert.nature.com/ctt?kn=69&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Hydrogen bonding at the water surface revealed by isotopic dilution s
pectroscopy
Igor V. Stiopkin, Champika Weeraman, Piotr A. Pieniazek, Fadel Y.
Shalhout, James L. Skinner et al.
The air-water interface is perhaps the most common liquid interface. It...
http://links.ealert.nature.com/ctt?kn=76&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Irregular tropical glacier retreat over the Holocene epoch driven
by progressive warming
Vincent Jomelli, Myriam Khodri, Vincent Favier, Daniel Brunstein,
Marie-Pierre Ledru et al.
The causes and timing of tropical glacier fluctuations during the
Holocene epoc...
http://links.ealert.nature.com/ctt?kn=9&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** X-ray illumination of the ejecta of supernova 1987A
J. Larsson, C. Fransson, G. Ostlin, P. Groningsson, A. Jerkstrand
et al.
When a massive star explodes as a supernova, substantial amounts of
radioactive...
http://links.ealert.nature.com/ctt?kn=75&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Hydrogen-poor superluminous stellar explosions
R. M. Quimby, S. R. Kulkarni, M. M. Kasliwal, A. Gal-Yam, I. Arcavi
et al.
Supernovae are stellar explosions driven by gravitational or
thermonuclear ener...
http://links.ealert.nature.com/ctt?kn=72&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** A low mass for Mars from Jupiter's early gas-driven migration
Kevin J. Walsh, Alessandro Morbidelli, Sean N. Raymond, David P.
O'Brien and Avi M. Mandell
Jupiter and Saturn formed in a few million years (ref. 1) from a
gas-dominated ...
http://links.ealert.nature.com/ctt?kn=73&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** The electromotive force of MnAs nanoparticles
D. C. Ralph
Arising from P. N. Hai, S. Ohya, M. Tanaka, S. E. Barnes & S. Maekawa.
Nature 4...
Magnetic tunnel junctions can produce large magnetoresistance effects
that are ...
http://links.ealert.nature.com/ctt?kn=11&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Complex systems: Unzipping Zipf's law
Lada Adamic
One mathematical model can account for power-law distributions in a
variety of systems. Eschewing system-specific assumptions, it utilizes
a shared feature of the observed distributions: they all describe the
division of items into groups.
http://links.ealert.nature.com/ctt?kn=10&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Physical chemistry: Water's wafer-thin surface
Pavel Jungwirth
A combination of vibrational spectroscopy and molecular calculations
reveals that only the surface layer of water at the interface with air
has a distinctly different structure from the bulk liquid.
http://links.ealert.nature.com/ctt?kn=77&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Quantum physics: How to catch a wave
Onur Hosten
The wavefunction is a central mathematical entity in quantum physics.
It is used to completely describe the state of a system. A means of
probing it directly is now on hand.
http://links.ealert.nature.com/ctt?kn=74&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

NEWS & COMMENT
** Particle physics: Antihydrogen held captive
http://links.ealert.nature.com/ctt?kn=12&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Photonics: Light threaded through tiny gap
http://links.ealert.nature.com/ctt?kn=1&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Materials science: Switching strength on or off
http://links.ealert.nature.com/ctt?kn=2&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Cyberwarfare challenge
National cybersecurity plans should go beyond the cold-war mentality
of an arms race and focus more on linking traditional computer security
with protections for industrial control systems.
http://links.ealert.nature.com/ctt?kn=109&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=107&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** More News & Comment on PHYSICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=67&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

======================== EARTH AND ENVIRONMENTAL SCIENCES ========================
RESEARCH
** A current filamentation mechanism for breaking magnetic field lines
during reconnection
H. Che, J. F. Drake and M. Swisdak
During magnetic reconnection, the field lines must break and reconnect
to relea...
http://links.ealert.nature.com/ctt?kn=69&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** A low mass for Mars from Jupiter's early gas-driven migration
Kevin J. Walsh, Alessandro Morbidelli, Sean N. Raymond, David P. O'Brien
and Avi M. Mandell
Jupiter and Saturn formed in a few million years (ref. 1) from a gas-
dominated ...
http://links.ealert.nature.com/ctt?kn=73&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

NEWS & COMMENT
** Glaciology: Glacier modelling can reduce risks
http://links.ealert.nature.com/ctt?kn=4&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Geoscience: Permafrost thaws, wetlands shrink
http://links.ealert.nature.com/ctt?kn=5&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Second chances
Leaders must end a run of unmet pledges when they meet to discuss
sustainable development.
http://links.ealert.nature.com/ctt?kn=110&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Save our soils
Researchers must collaborate to manage one of the planet's most precious
and threatened resources - for food production and much more, says
Steve Banwart.
http://links.ealert.nature.com/ctt?kn=121&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** More News & Comment on EARTH AND ENVIRONMENTAL SCIENCES
http://links.ealert.nature.com/ctt?kn=66&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

======================== Specials - Outlook: Hepatitis C ========================
http://links.ealert.nature.com/ctt?kn=14&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Hepatitis C
Herb Brody
http://links.ealert.nature.com/ctt?kn=6&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Introduction: A smouldering public-health crisis
Lauren Gravitz
Long overshadowed by HIV, the hepatitis C virus is starting to take
its toll. A...
http://links.ealert.nature.com/ctt?kn=7&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Therapeutics: New drugs hit the target
Jana Schlutter
With two recently approved drugs and dozens more in the pipeline,
hepatitis C t...
http://links.ealert.nature.com/ctt?kn=33&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Perspective: Miles to go before we sleep
Charles Rice
New drugs are generating much excitement, but a cure for all will
take generati...
http://links.ealert.nature.com/ctt?kn=40&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Pharmacogenomics: Playing the odds
Amy Maxmen
Can doctors calculate a patient's chance of being cured by searching
their DNA?...
http://links.ealert.nature.com/ctt?kn=42&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Perspective: Recognizing resistance
Diana Sylvestre
The hepatitis C virus is endemic among injection drug users, who
could harbour ...
http://links.ealert.nature.com/ctt?kn=38&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Global health: A uniquely Egyptian epidemic
Mohammed Yahia
Egypt has the highest prevalence of hepatitis C worldwide. And the
epidemic wil...
http://links.ealert.nature.com/ctt?kn=39&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Research technique: The murine candidate
Elie Dolgin
Small animals that mimic human hepatitis C infection will help researchers
pinp...
http://links.ealert.nature.com/ctt?kn=26&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Vaccines: A moving target
Michael Eisenstein
The hepatitis C virus has a set of cunning ways to evade immunity, but
research...
http://links.ealert.nature.com/ctt?kn=27&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Diagnostics: A testing journey
Sarah DeWeerdt
Results ready in minutes and more efficacious drugs will help find and
treat th...
http://links.ealert.nature.com/ctt?kn=24&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

** Perspective: Test and treat this silent killer
Brian R. Edlin
The scourge of the hepatitis C virus in the United States is woefully
underesti...
http://links.ealert.nature.com/ctt?kn=25&ms=MzY2OTUwMTcS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAzNDEyOTQ4S0&mt=1&rt=0

The EDGE

Wednesday, June 8, 2011

Nature contents: 09 June 2011

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