Wednesday, June 1, 2011

Nature contents: 02 June 2011

Nature Alert
The science that matters. Every week.

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View Table of Contents http://links.ealert.nature.com/ctt?kn=47&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0


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=========================== ADVERTISEMENT ===========================

---THIS WEEK'S HIGHLIGHTS:

--Biological Sciences
-Ultra-prolonged activation of CO2-sensing neurons disorients mosquitoes
The isolation of odorants that modify carbon dioxide detection mechanisms
in the three deadliest mosquito species offers hope that malaria and
dengue fever might be controlled by interfering with insect vectors'
ability to detect a potential host's breath.
http://links.ealert.nature.com/ctt?kn=93&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

--Earth & Environmental Sciences
-A hydrothermal origin for isotopically anomalous cap dolostone cements from south China
Earth's emergence from perhaps its most severe ice age, the Marinoan
'snowball' glaciation some 635 million years ago, is thought to be
linked with a massive release of trapped methane. But now a key line
of evidence for this exit route from a snowball Earth is questioned.
http://links.ealert.nature.com/ctt?kn=94&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

--Physical Sciences
-A graphene-based broadband optical modulator
The development of a graphene-based optical modulator integrated on
a silicon chip opens exciting possibilities for application in the
on-chip optical communications field.
http://links.ealert.nature.com/ctt?kn=90&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

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Nature Publishing Index China 2010 NEW!

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of the Nature Publishing Index 2010 China. The Nature Publishing Index
2010 China reports the rankings of research institutions and cities in
mainland China and Hong Kong based on their output of research articles
in Nature journals and points to where some of best research is being
conducted in China.

View the China rankings now!
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--Podcast & Video
-This week, worms from hell, early human lifestyles and quantum computing.
Plus, the best of the rest from Nature.
http://links.ealert.nature.com/ctt?kn=121&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

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======================== NEWS AND COMMENT ========================

Read daily news coverage http://links.ealert.nature.com/ctt?kn=122&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

EDITORIALS
** A big disease with a little name
Three decades on from the first published cases of what would later
be recognized as AIDS, the social and cultural challenges of the
disease remain.
http://links.ealert.nature.com/ctt?kn=92&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Board the eurostar
Europe's science meeting is getting bigger and better. Now's the
time to get involved for 2012.
http://links.ealert.nature.com/ctt?kn=100&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Gold mine
A trove of worms found in the deep subsurface biosphere illustrates
the ubiquity of life.
http://links.ealert.nature.com/ctt?kn=101&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

WORLD VIEW
** China needs no foreign help to feed itself
China can meet the demands of its growing population without importing
grain from elsewhere, says Peng Gong.
http://links.ealert.nature.com/ctt?kn=16&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

SEVEN DAYS
** Seven days: 27 May-2 June 2011
The week in science
http://links.ealert.nature.com/ctt?kn=19&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

NEWS
** A new eye on biodiversity
Airborne observatory will use chemical clues to map and assess
tropical ecosystems.
http://links.ealert.nature.com/ctt?kn=18&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Scientists on trial over L'Aquila deaths
Seismologists charged for giving apparent reassurances on Italian
earthquake risks.
http://links.ealert.nature.com/ctt?kn=17&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Japan quake rocks fusion project
Damaged facilities force further delay to ITER experiment.
http://links.ealert.nature.com/ctt?kn=30&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Tevatron's legacy set to disappear
Lack of long-term preservation plan threatens to leave key information
inaccessible for future analysis.
http://links.ealert.nature.com/ctt?kn=31&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Furore erupts over Turkish test cipher
University entrance-exam fiasco hits election campaign.
http://links.ealert.nature.com/ctt?kn=25&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** First sale for quantum computing
But critics say that D-Wave's system is still something of a black box.
http://links.ealert.nature.com/ctt?kn=24&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Will you take the 'arsenic-life' test?
Critiques prompt researchers to offer samples of poison-tolerant
microbe to doubters.
http://links.ealert.nature.com/ctt?kn=22&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

FEATURES
** Physics meets cancer: The disruptor
Paul Davies likes to ask big questions. But how did the freethinking
cosmologist suddenly find himself probing the physics of cancer?
http://links.ealert.nature.com/ctt?kn=20&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Quantum computing: The power of discord
Physicists have always thought quantum computing is hard because
quantum states are incredibly fragile. But could noise and messiness
actually help things along?
http://links.ealert.nature.com/ctt?kn=27&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

COMMENT
** Children of the AIDS pandemic
Practical support and psychosocial interventions are desperately needed
to help those dealing with the fallout of AIDS, says Lucie Cluver.
http://links.ealert.nature.com/ctt?kn=95&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Stigma impedes AIDS prevention
Medical advances cannot help those who deny they are at risk of HIV and
avoid HIV tests. Salim S. Abdool Karim describes how such attitudes may
be overcome.
http://links.ealert.nature.com/ctt?kn=97&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

BOOKS AND ARTS
** Economics: Trial and error
An impressive book argues that we should embrace failure in economic
and social progress, finds Matt Ridley.
http://links.ealert.nature.com/ctt?kn=87&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=74&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Neuroscience: Recalling the future
Our memories may be tools for working out what's to come and what to
do about it, finds Linnaea Ostroff.
http://links.ealert.nature.com/ctt?kn=72&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Q&A: Musical intelligence
Eduardo Reck Miranda is a composer and leading researcher in artificial
intelligence in music, based at the University of Plymouth, UK. A
revised version of his Sacra Conversazione - five movements for
string orchestra, percussion and electronics - will be performed
on 9 June in London. He explains what music can tell us about speech,
physiology and cognition.
http://links.ealert.nature.com/ctt?kn=78&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

CORRESPONDENCE
** Respect limits of embryo patents
Roland Hipp and Peter Liese
http://links.ealert.nature.com/ctt?kn=76&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Cameroon: not ready for REDD+
Benoit Bosquet
http://links.ealert.nature.com/ctt?kn=82&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Cameroon: listening to indigenous peoples
David Hoyle
http://links.ealert.nature.com/ctt?kn=80&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Population mapping of poor countries
Andrew Tatem and Catherine Linard
http://links.ealert.nature.com/ctt?kn=85&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

OBITUARY
** Willard Boyle (1924-2011)
Physicist who helped invent the 'eye of the digital camera'.
http://links.ealert.nature.com/ctt?kn=84&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0


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======================== BIOLOGICAL SCIENCES ========================
RESEARCH
** Crystal structure of the FimD usher bound to its cognate FimC-FimH
substrate
Gilles Phan, Han Remaut, Tao Wang, William J. Allen, Katharina F. Pirker
et al.
Type 1 pili are the archetypal representative of a widespread class of
adhesive...
http://links.ealert.nature.com/ctt?kn=102&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Principles of activation and permeation in an anion-selective
Cys-loop receptor
Ryan E. Hibbs and Eric Gouaux
Fast inhibitory neurotransmission is essential for nervous system
function and ...
http://links.ealert.nature.com/ctt?kn=111&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Strontium isotope evidence for landscape use by early hominins
Sandi R. Copeland, Matt Sponheimer, Darryl J. de Ruiter, Julia A.
Lee-Thorp, Daryl Codron et al.
Ranging and residence patterns among early hominins have been indirectly
inferr...
http://links.ealert.nature.com/ctt?kn=109&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Nematoda from the terrestrial deep subsurface of South Africa
G. Borgonie, A. Garcia-Moyano, D. Litthauer, W. Bert, A. Bester et al.
Since its discovery over two decades ago, the deep subsurface biosphere
has bee...
http://links.ealert.nature.com/ctt?kn=108&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Earliest evidence of mammalian social behaviour in the basal
Tertiary of Bolivia
Sandrine Ladeveze, Christian de Muizon, Robin M. D. Beck, Damien
Germain and Ricardo Cespedes-Paz
The vast majority of Mesozoic and early Cenozoic metatherian mammals
(extinct r...
http://links.ealert.nature.com/ctt?kn=107&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Ultra-prolonged activation of CO2-sensing neurons disorients mosquitoes
Stephanie Lynn Turner, Nan Li, Tom Guda, John Githure, Ring T. Carde
et al.
Carbon dioxide (CO2) present in exhaled air is the most important
sensory cue f...
http://links.ealert.nature.com/ctt?kn=93&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Cryptic genetic variation promotes rapid evolutionary adaptation
in an RNA enzyme
Eric J. Hayden, Evandro Ferrada and Andreas Wagner
Cryptic variation is caused by the robustness of phenotypes to mutations.
Crypt...
http://links.ealert.nature.com/ctt?kn=51&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Non-apoptotic role of BID in inflammation and innate immunity
Garabet Yeretssian, Ricardo G. Correa, Karine Doiron, Patrick Fitzgerald,
Christopher P. Dillon et al.
Innate immunity is a fundamental defence response that depends on
evolutionaril...
http://links.ealert.nature.com/ctt?kn=42&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Glutamate induces de novo growth of functional spines in developing
cortex
Hyung-Bae Kwon and Bernardo L. Sabatini
Mature cortical pyramidal neurons receive excitatory inputs onto small
protrusi...
http://links.ealert.nature.com/ctt?kn=43&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT
hybrids
Dawn M. Wenzel, Alexei Lissounov, Peter S. Brzovic and Rachel E. Klevit
Although the functional interaction between ubiquitin-conjugating
enzymes (E2s)...
http://links.ealert.nature.com/ctt?kn=36&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter
transporter homologue
Yongfang Zhao, Daniel S. Terry, Lei Shi, Matthias Quick, Harel Weinstein
et al.
Neurotransmitter/Na+ symporters (NSSs) terminate neuronal signalling
by recaptu...
http://links.ealert.nature.com/ctt?kn=38&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Condensin association with histone H2A shapes mitotic chromosomes
Kenji Tada, Hiroaki Susumu, Takeshi Sakuno and Yoshinori Watanabe
Chromosome structure is dynamically regulated during cell division,
and this re...
http://links.ealert.nature.com/ctt?kn=115&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in
myeloid cells
James A. Stefater III, Ian Lewkowich, Sujata Rao, Giovanni Mariggi,
April C. Carpenter et al.
Myeloid cells are a feature of most tissues. Here we show that during
developme...
http://links.ealert.nature.com/ctt?kn=116&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Latent TGF-[bgr] binding protein 3 identifies a second heart field
in zebrafish
Yong Zhou, Timothy J. Cashman, Kathleen R. Nevis, Pablo Obregon,
Sara A. Carney et al.
The four-chambered mammalian heart develops from two fields of cardiac
progenit...
http://links.ealert.nature.com/ctt?kn=96&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Single-molecule fluorescence reveals sequence-specific misfolding
in multidomain proteins
Madeleine B. Borgia, Alessandro Borgia, Robert B. Best, Annette Steward,
Daniel Nettels et al.
A large range of debilitating medical conditions is linked to protein
misfoldin...
http://links.ealert.nature.com/ctt?kn=106&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** A gene regulatory network controlling the embryonic specification
of endoderm
Isabelle S. Peter and Eric H. Davidson
Specification of endoderm is the prerequisite for gut formation in
the embryoge...
http://links.ealert.nature.com/ctt?kn=104&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Induction of human neuronal cells by defined transcription factors
Zhiping P. Pang, Nan Yang, Thomas Vierbuchen, Austin Ostermeier,
Daniel R. Fuentes et al.
Somatic cell nuclear transfer, cell fusion, or expression of lineage-
specific f...
http://links.ealert.nature.com/ctt?kn=26&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Erratum: Duplications of the neuropeptide receptor gene VIPR2 confer significant
risk for schizophrenia
Vladimir Vacic, Shane McCarthy, Dheeraj Malhotra, Fiona Murray,
Hsun-Hua Chou et al.
http://links.ealert.nature.com/ctt?kn=34&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Malaria: Mosquitoes bamboozled
Mark Stopfer
Mosquitoes harbouring the malaria parasite follow pulses of carbon
dioxide exhaled by their human prey to track them down. A novel set
of chemicals can distract these insects by disrupting their sense of
smell.
http://links.ealert.nature.com/ctt?kn=39&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Immunology: In command of commensals
Menno van Lookeren Campagne and Vishva M. Dixit
Humans must maintain a balanced composition for the trillions of
commensal microbes that inhabit their gut, but how they do this is
largely unclear. It now emerges that one factor is a molecular pathway
in gut epithelial cells.
http://links.ealert.nature.com/ctt?kn=41&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Palaeoanthropology: In search of the australopithecines
Margaret J. Schoeninger
Evidence from strontium isotope ratios preserved in fossil teeth
provides a glimpse into the group dynamics and ranging habits of
the australopithecines that can be compared with the patterns for
modern primates.
http://links.ealert.nature.com/ctt?kn=32&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Molecular evolution: Hidden diversity sparks adaptation
Jeremy A. Draghi and Joshua B. Plotkin
Although some genetic mutations have clear effects, others have been
considered neutral and inconsequential. Such cryptic mutations can
nonetheless facilitate adaptation to new environments.
http://links.ealert.nature.com/ctt?kn=33&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

NEWS & COMMENT
** Neuroscience: Pay attention to the neurons
http://links.ealert.nature.com/ctt?kn=35&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Stem cells: Gene repair tool for stem cells
http://links.ealert.nature.com/ctt?kn=62&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Ecology: Speciation drives plant extinction
http://links.ealert.nature.com/ctt?kn=60&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Molecular neuroscience: Bitter breath for lung airways
http://links.ealert.nature.com/ctt?kn=61&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Anthropology: Kiwi DNA tells Maori history
http://links.ealert.nature.com/ctt?kn=58&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Animal behaviour: Turtle embryos seek sunny side
http://links.ealert.nature.com/ctt?kn=59&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Microbiology: Protein behind protozoan power
http://links.ealert.nature.com/ctt?kn=56&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Molecular biology: Cells stressed from hunger
http://links.ealert.nature.com/ctt?kn=57&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** A big disease with a little name
Three decades on from the first published cases of what would later be
recognized as AIDS, the social and cultural challenges of the disease
remain.
http://links.ealert.nature.com/ctt?kn=92&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Gold mine
A trove of worms found in the deep subsurface biosphere illustrates
the ubiquity of life.
http://links.ealert.nature.com/ctt?kn=101&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Children of the AIDS pandemic
Practical support and psychosocial interventions are desperately needed
to help those dealing with the fallout of AIDS, says Lucie Cluver.
http://links.ealert.nature.com/ctt?kn=95&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Stigma impedes AIDS prevention
Medical advances cannot help those who deny they are at risk of HIV and
avoid HIV tests. Salim S. Abdool Karim describes how such attitudes may
be overcome.
http://links.ealert.nature.com/ctt?kn=97&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Economics: Trial and error
An impressive book argues that we should embrace failure in economic
and social progress, finds Matt Ridley.
http://links.ealert.nature.com/ctt?kn=87&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=74&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Neuroscience: Recalling the future
Our memories may be tools for working out what's to come and what to
do about it, finds Linnaea Ostroff.
http://links.ealert.nature.com/ctt?kn=72&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Q&A: Musical intelligence
Eduardo Reck Miranda is a composer and leading researcher in artificial
intelligence in music, based at the University of Plymouth, UK. A
revised version of his Sacra Conversazione - five movements for
string orchestra, percussion and electronics - will be performed
on 9 June in London. He explains what music can tell us about speech,
physiology and cognition.
http://links.ealert.nature.com/ctt?kn=78&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Respect limits of embryo patents
Roland Hipp and Peter Liese
http://links.ealert.nature.com/ctt?kn=76&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0


** More News & Comment on BIOLOGICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=67&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0


=========================== ADVERTISEMENT ===========================

Nature Reviews Molecular Cell Biology
Free Poster - The identity and properties of mesenchymal stem cells
http://links.ealert.nature.com/ctt?kn=114&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

This Poster provides an overview of the identity of MSCs in vivo and
the effects of their in vitro-expanded progeny, and highlights key
questions in the field regarding the biology of these elusive cells.

Produced with support from:
STEMCELL Technologies

=====================================================================

======================== CHEMICAL SCIENCES ========================
RESEARCH
** Principles of activation and permeation in an anion-selective
Cys-loop receptor
Ryan E. Hibbs and Eric Gouaux
Fast inhibitory neurotransmission is essential for nervous system
function and ...
http://links.ealert.nature.com/ctt?kn=111&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Cryptic genetic variation promotes rapid evolutionary adaptation
in an RNA enzyme
Eric J. Hayden, Evandro Ferrada and Andreas Wagner
Cryptic variation is caused by the robustness of phenotypes to
mutations. Crypt...
http://links.ealert.nature.com/ctt?kn=51&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Non-apoptotic role of BID in inflammation and innate immunity
Garabet Yeretssian, Ricardo G. Correa, Karine Doiron, Patrick Fitzgerald,
Christopher P. Dillon et al.
Innate immunity is a fundamental defence response that depends on
evolutionaril...
http://links.ealert.nature.com/ctt?kn=42&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT
hybrids
Dawn M. Wenzel, Alexei Lissounov, Peter S. Brzovic and Rachel E. Klevit
Although the functional interaction between ubiquitin-conjugating
enzymes (E2s)...
http://links.ealert.nature.com/ctt?kn=36&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter
transporter homologue
Yongfang Zhao, Daniel S. Terry, Lei Shi, Matthias Quick, Harel Weinstein
et al.
Neurotransmitter/Na+ symporters (NSSs) terminate neuronal signalling
by recaptu...
http://links.ealert.nature.com/ctt?kn=38&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Molecular evolution: Hidden diversity sparks adaptation
Jeremy A. Draghi and Joshua B. Plotkin
Although some genetic mutations have clear effects, others have been
considered neutral and inconsequential. Such cryptic mutations can
nonetheless facilitate adaptation to new environments.
http://links.ealert.nature.com/ctt?kn=33&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

NEWS & COMMENT
** Chemistry: Crystals on water's edge
http://links.ealert.nature.com/ctt?kn=54&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=74&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0


** More News & Comment on CHEMICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=40&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0


========================
PHYSICAL SCIENCES
========================
RESEARCH
** The thermodynamic meaning of negative entropy
Lidia del Rio, Johan Aberg, Renato Renner, Oscar Dahlsten and Vlatko
Vedral
The heat generated by computations is not only an obstacle to circuit
miniaturi...
http://links.ealert.nature.com/ctt?kn=52&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** A graphene-based broadband optical modulator
Ming Liu, Xiaobo Yin, Erick Ulin-Avila, Baisong Geng, Thomas Zentgraf
et al.
Integrated optical modulators with high modulation speed, small
footprint and l...
http://links.ealert.nature.com/ctt?kn=90&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** A hydrothermal origin for isotopically anomalous cap dolostone
cements from south China
Thomas F. Bristow, Magali Bonifacie, Arkadiusz Derkowski, John M.
Eiler and John P. Grotzinger
The release of methane into the atmosphere through destabilization
of clathrate...
http://links.ealert.nature.com/ctt?kn=94&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** A dynamic early East Antarctic Ice Sheet suggested by ice-covered
fjord landscapes
Duncan A. Young, Andrew P. Wright, Jason L. Roberts, Roland C. Warner,
Neal W. Young et al.
The first Cenozoic ice sheets initiated in Antarctica from the
Gamburtsev Subgl...
http://links.ealert.nature.com/ctt?kn=9&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** A current filamentation mechanism for breaking magnetic field
lines during reconnection
H. Che, J. F. Drake and M. Swisdak
During magnetic reconnection, the field lines must break and reconnect
to relea...
http://links.ealert.nature.com/ctt?kn=55&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Mineralogical constraints on Precambrian pCO2
Christopher T. Reinhard and Noah J. Planavsky
Arising from M. T. Rosing, D. K. Bird, N. H. Sleep & C. J. Bjerrum
Nature 464, ...
Rosing and others recently proposed a new model for the early Earth's a...
http://links.ealert.nature.com/ctt?kn=12&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Low pCO2 in the pore water, not in the Archean air
N. Dauphas and J. F. Kasting
Arising from M. T. Rosing, D. K. Bird, N. H. Sleep & C. J. Bjerrum
Nature 464, ...
The solar luminosity during the Archean (3.8 to 2.5 billion years
ago) was 20|[...
http://links.ealert.nature.com/ctt?kn=1&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Faint young Sun paradox remains
Colin Goldblatt and Kevin J. Zahnle
Arising from M. T. Rosing, D. K. Bird, N. H. Sleep & C. J. Bjerrum,
Nature 464,...
The Sun was fainter when the Earth was young, but the climate was
generally at ...
http://links.ealert.nature.com/ctt?kn=2&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Rosing, Bird, Sleep & Bjerrum reply
Minik T. Rosing, Dennis K. Bird, Norman H. Sleep and Christian J.
Bjerrum
Replying to C. T. Reinhard & N. J. Planavsky p...
http://links.ealert.nature.com/ctt?kn=4&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Quantum information: Entanglement as elbow grease
Patrick Hayden
Quantum correlations have long been recognized as an informational
resource for quantum communication and computation. It now seems that
they can also do physical work.
http://links.ealert.nature.com/ctt?kn=10&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Climate change: Ancient Antarctic fjords
Sandra Passchier
The East Antarctic ice sheet, the largest in the world, lies seemingly
frozen in time. Discovery of a rugged landscape buried beneath the
thick ice provides evidence of a more dynamic past.
http://links.ealert.nature.com/ctt?kn=11&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

NEWS & COMMENT
** Physics: Location counts in search for waves
http://links.ealert.nature.com/ctt?kn=5&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=74&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Cameroon: listening to indigenous peoples
David Hoyle
http://links.ealert.nature.com/ctt?kn=80&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Willard Boyle (1924-2011)
Physicist who helped invent the 'eye of the digital camera'.
http://links.ealert.nature.com/ctt?kn=84&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0


** More News & Comment on PHYSICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=50&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0


======================== EARTH AND ENVIRONMENTAL SCIENCES ========================
RESEARCH
** A hydrothermal origin for isotopically anomalous cap dolostone
cements from south China
Thomas F. Bristow, Magali Bonifacie, Arkadiusz Derkowski, John M. Eiler
and John P. Grotzinger
The release of methane into the atmosphere through destabilization
of clathrate...
http://links.ealert.nature.com/ctt?kn=94&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** A dynamic early East Antarctic Ice Sheet suggested by ice-covered
fjord landscapes
Duncan A. Young, Andrew P. Wright, Jason L. Roberts, Roland C. Warner,
Neal W. Young et al.
The first Cenozoic ice sheets initiated in Antarctica from the
Gamburtsev Subgl...
http://links.ealert.nature.com/ctt?kn=9&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Nematoda from the terrestrial deep subsurface of South Africa
G. Borgonie, A. Garcia-Moyano, D. Litthauer, W. Bert, A. Bester et al.
Since its discovery over two decades ago, the deep subsurface biosphere
has bee...
http://links.ealert.nature.com/ctt?kn=108&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** A current filamentation mechanism for breaking magnetic field lines
during reconnection
H. Che, J. F. Drake and M. Swisdak
During magnetic reconnection, the field lines must break and reconnect
to relea...
http://links.ealert.nature.com/ctt?kn=55&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Mineralogical constraints on Precambrian pCO2
Christopher T. Reinhard and Noah J. Planavsky
Arising from M. T. Rosing, D. K. Bird, N. H. Sleep & C. J. Bjerrum
Nature 464, ...
Rosing and others recently proposed a new model for the early Earth's a...
http://links.ealert.nature.com/ctt?kn=12&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Low pCO2 in the pore water, not in the Archean air
N. Dauphas and J. F. Kasting
Arising from M. T. Rosing, D. K. Bird, N. H. Sleep & C. J. Bjerrum
Nature 464, ...
The solar luminosity during the Archean (3.8 to 2.5 billion years ago)
was 20|[...
http://links.ealert.nature.com/ctt?kn=1&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Faint young Sun paradox remains
Colin Goldblatt and Kevin J. Zahnle
Arising from M. T. Rosing, D. K. Bird, N. H. Sleep & C. J. Bjerrum,
Nature 464,...
The Sun was fainter when the Earth was young, but the climate was
generally at ...
http://links.ealert.nature.com/ctt?kn=2&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Rosing, Bird, Sleep & Bjerrum reply
Minik T. Rosing, Dennis K. Bird, Norman H. Sleep and Christian J.
Bjerrum
Replying to C. T. Reinhard & N. J. Planavsky p...
http://links.ealert.nature.com/ctt?kn=4&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Climate change: Ancient Antarctic fjords
Sandra Passchier
The East Antarctic ice sheet, the largest in the world, lies seemingly
frozen in time. Discovery of a rugged landscape buried beneath the
thick ice provides evidence of a more dynamic past.
http://links.ealert.nature.com/ctt?kn=11&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

NEWS & COMMENT
** Books in brief
http://links.ealert.nature.com/ctt?kn=74&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Cameroon: not ready for REDD+
Benoit Bosquet
http://links.ealert.nature.com/ctt?kn=82&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Cameroon: listening to indigenous peoples
David Hoyle
http://links.ealert.nature.com/ctt?kn=80&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0


** More News & Comment on EARTH AND ENVIRONMENTAL SCIENCES
http://links.ealert.nature.com/ctt?kn=49&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

=========================== ADVERTISEMENT ===========================

Naturejobs Career Expo - London - UK's largest fair and conference
focused exclusively on the scientific world.
22 September 2011
Exhibition is FREE
REGISTER TODAY: http://links.ealert.nature.com/ctt?kn=128&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

=====================================================================


======================== CAREERS & JOBS ========================
** Back to the bench
Grants and fellowship programmes can lessen the shock of re-entry for
researchers who have taken a career break.
http://links.ealert.nature.com/ctt?kn=126&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Communication: Voices for Careers
Columnist competition yields six winners.
http://links.ealert.nature.com/ctt?kn=86&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** Board the eurostar
Europe's science meeting is getting bigger and better. Now's the time
to get involved for 2012.
http://links.ealert.nature.com/ctt?kn=100&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0

** First sale for quantum computing
But critics say that D-Wave's system is still something of a black box.
http://links.ealert.nature.com/ctt?kn=24&ms=MzY2NzMyNDkS1&r=MjA1NzcwMjE4MQS2&b=2&j=MTAyODgzMTY4S0&mt=1&rt=0


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