Wednesday, May 4, 2011

Nature contents: 05 May 2011

Nature Alert
The science that matters. Every week.

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View Table of Contents http://links.ealert.nature.com/ctt?kn=40&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

=========================== ADVERTISEMENT ===========================
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http://links.ealert.nature.com/ctt?kn=25&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0
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=========================== ADVERTISEMENT ===========================

---THIS WEEK'S HIGHLIGHTS:

--Physical Sciences
-Single-ion quantum lock-in amplifier
The 'lock-in' technique is a valuable tool in experimental physics,
used to increase measurement sensitivity while reducing
susceptibility to noise. Now a quantum analogue has been developed,
with the potential to enhance the sensitivity of any quantum sensor.
[ http://links.ealert.nature.com/ctt?kn=84&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0 ]

--Biological Sciences
-Evolved structure of language shows lineage-specific trends in
word-order universals
Analysis of word-order variation in over a third of the world's 7,000
surviving languages suggests that cultural evolution, rather than
either of the two previous theories put forward by Noam Chomsky and
Joseph Greenberg, can explain most aspects of linguistic structure.
[ http://links.ealert.nature.com/ctt?kn=87&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0 ]

--Biological Sciences
-Body plan innovation in treehoppers through the evolution of an
extra wing-like appendage
The bizarre and varied 'helmet' structure sported by the cicada-like
insects known as treehoppers turns out to be -- in evolutionary terms
-- virtually a third pair of wings. The discovery of this previously
unknown variation of the blueprint for insects illustrates how a
structure relieved of its original role is free to evolve in novel
directions.
[ http://links.ealert.nature.com/ctt?kn=81&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0 ]

--Podcast & Video
-This week, companies race into space, treehopper insects help to
explain evolutionary novelty, and the workings of the hummingbird's
tongue.
[ http://links.ealert.nature.com/ctt?kn=114&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0 ]

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======================== NEWS AND COMMENT ========================
Read daily news coverage http://links.ealert.nature.com/ctt?kn=115&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

EDITORIALS
** Storm warning
Political hostility over global-warming policy in the United States
is causing collateral damage. Plans for a National Climate Service
deserve better.
http://links.ealert.nature.com/ctt?kn=83&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Flagship funding
The European Union plans to throw serious money at serious problems.
http://links.ealert.nature.com/ctt?kn=91&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

WORLD VIEW
** 2 °C or not 2 °C? That is the climate question
Targets to limit the global temperature rise won't prevent climate
disruption. Tim Lenton says that policy-makers should focus on
regional impacts.
http://links.ealert.nature.com/ctt?kn=26&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

SEVEN DAYS
** Seven days: 29 Apr-5 May 2011
The week in science
http://links.ealert.nature.com/ctt?kn=15&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

NEWS
** Antiuniverse here we come
A controversial cosmic-ray detector destined for the International
Space Station will soon get to prove its worth.
http://links.ealert.nature.com/ctt?kn=14&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** China unveils its space station
Plans for modest outpost solidify 'go it alone' approach.
http://links.ealert.nature.com/ctt?kn=13&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Wayward whale not a fluke
Warming Arctic cited as likely cause of freak migration.
http://links.ealert.nature.com/ctt?kn=20&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** A how-to for peer review
A guide surveys the range of practices in Europe -- and offers
suggestions for improvement.
http://links.ealert.nature.com/ctt?kn=19&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** US farm-science head quits
Departure of director from National Institute of Food and Agriculture
casts uncertainty over future of flagship funding programme.
http://links.ealert.nature.com/ctt?kn=17&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** US stem-cell funding ban overturned
Appeals court decision bodes well for continued NIH support of
controversial research.
http://links.ealert.nature.com/ctt?kn=16&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

FEATURE
** Space science: Along for the ride
Reusable commercial rockets will soon be able to take scientists
-- and tourists -- on suborbital spaceflights. Are these vehicles vital
research tools, or an expensive dead end?
http://links.ealert.nature.com/ctt?kn=22&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

COMMENT
** From isotopes to the stars
Creating more exotic isotopes will reveal the stellar formation of
atoms -- a fitting tribute to Ernest Rutherford,
say Michael Thoennessen and Bradley Sherrill.
http://links.ealert.nature.com/ctt?kn=92&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

BOOKS AND ARTS
** Environment: Water, water everywhere...
Margaret Catley-Carlson wonders why humanity places so little value
on its most basic resource.
http://links.ealert.nature.com/ctt?kn=88&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Technology: Together, bit by bit
A historian's insights into digital culture fascinate George Rousseau.
http://links.ealert.nature.com/ctt?kn=90&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=79&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Q&A: Illuminating the dark
As he releases a 3D documentary about the prehistoric paintings in
Chauvet Cave in southern France, Werner Herzog -- the German director
of Fitzcarraldo and Grizzly Man -- talks about cave art and the
hostility of nature.
http://links.ealert.nature.com/ctt?kn=67&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

CORRESPONDENCE
** NIH revamp: US health care at fault
Thomas E. DeCoursey
http://links.ealert.nature.com/ctt?kn=66&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** NIH revamp: real issue is resources
Russ Altman
http://links.ealert.nature.com/ctt?kn=70&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** NIH revamp: avoid a redundant revolution
John Robinson
http://links.ealert.nature.com/ctt?kn=69&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** UNESCO helps manage tsunamis
Irina Bokova
http://links.ealert.nature.com/ctt?kn=72&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** It is rational to doubt Fukushima reports
Peter M. Sandman and Jody Lanard
http://links.ealert.nature.com/ctt?kn=71&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

CORRECTIONS
** Correction
http://links.ealert.nature.com/ctt?kn=21&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Correction
http://links.ealert.nature.com/ctt?kn=74&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0


=========================== ADVERTISEMENT ===========================
The EMBO Meeting 2011, 10-13 September, Vienna

More than 120 world-class scientific speakers, including: Richard Axel,
Susan Lindquist and Eric Wieschaus.

Three plenary sessions: microbiology of infection, genome evolution
and neuroscience.

21 concurrent sessions exploring classical fields of research and new
frontiers in molecular biology.

Submit your abstract by: 22 May 2011

http://links.ealert.nature.com/ctt?kn=62&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0
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======================== BIOLOGICAL SCIENCES ========================
RESEARCH
** Mapping and analysis of chromatin state dynamics in nine human cell types
Jason Ernst, Pouya Kheradpour, Tarjei S. Mikkelsen, Noam Shoresh,
Lucas D. Ward et al.
Chromatin profiling has emerged as a powerful means of genome annotation
and de...
http://links.ealert.nature.com/ctt?kn=73&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Crystal structure of a phosphorylation-coupled saccharide transporter
Yu Cao, Xiangshu Jin, Elena J. Levin, Hua Huang, Yinong Zong et al.
Saccharides have a central role in the nutrition of all living
organisms. Where...
http://links.ealert.nature.com/ctt?kn=109&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Crystal structure of oxygen-evolving photosystem II at a resolution
of 1.9 A
Yasufumi Umena, Keisuke Kawakami, Jian-Ren Shen and Nobuo Kamiya
Photosystem II is the site of photosynthetic water oxidation and
contains 20 su...
http://links.ealert.nature.com/ctt?kn=110&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Evolved structure of language shows lineage-specific trends in
word-order universals
Michael Dunn, Simon J. Greenhill, Stephen C. Levinson and Russell D. Gray
Languages vary widely but not without limit. The central goal of
linguistics is...
http://links.ealert.nature.com/ctt?kn=87&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Body plan innovation in treehoppers through the evolution of an
extra wing-like appendage
Benjamin Prud'homme, Caroline Minervino, Melanie Hocine,
Jessica D. Cande, Aicha Aouane et al.
Body plans, which characterize the anatomical organization of animal
groups of ...
http://links.ealert.nature.com/ctt?kn=81&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Functional specificity of local synaptic connections in neocortical
networks
Ho Ko, Sonja B. Hofer, Bruno Pichler, Katherine A. Buchanan,
P. Jesper Sjostrom et al.
Neuronal connectivity is fundamental to information processing in the
brain. Th...
http://links.ealert.nature.com/ctt?kn=89&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** DISC1-dependent switch from progenitor proliferation to migration
in the developing cortex
Koko Ishizuka, Atsushi Kamiya, Edwin C. Oh, Hiroaki Kanki,
Saurav Seshadri et al.
Regulatory mechanisms governing the sequence from progenitor cell
proliferation...
http://links.ealert.nature.com/ctt?kn=101&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Ancestral polyploidy in seed plants and angiosperms
Yuannian Jiao, Norman J. Wickett, Saravanaraj Ayyampalayam,
Andre S. Chanderbali, Lena Landherr et al.
Whole-genome duplication (WGD), or polyploidy, followed by gene loss
and diploi...
http://links.ealert.nature.com/ctt?kn=99&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Suppression of lung adenocarcinoma progression by Nkx2-1
Monte M. Winslow, Talya L. Dayton, Roel G. W. Verhaak,
Caroline Kim-Kiselak, Eric L. Snyder et al.
Despite the high prevalence and poor outcome of patients with
metastatic lung c...
http://links.ealert.nature.com/ctt?kn=96&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** CPEB and two poly(A) polymerases control miR-122 stability and p53
mRNA translation
David M. Burns, Andrea D'Ambrogio, Stephanie Nottrott and Joel D. Richter
Cytoplasmic polyadenylation-induced translation controls germ cell
development,...
http://links.ealert.nature.com/ctt?kn=94&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Enzyme-catalysed [4+2] cycloaddition is a key step in
the biosynthesis of spinosyn A
Hak Joong Kim, Mark W. Ruszczycky, Sei-hyun Choi, Yung-nan Liu and
Hung-wen Liu
The Diels-Alder reaction is a [4+2] cycloaddition reactio...
http://links.ealert.nature.com/ctt?kn=107&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Sequential interactions with Sec23 control the direction of vesicle
traffic
Christopher Lord, Deepali Bhandari, Shekar Menon, Majid Ghassemian,
Deborah Nycz et al.
How the directionality of vesicle traffic is achieved remains an
important unan...
http://links.ealert.nature.com/ctt?kn=105&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Learning-related feedforward inhibitory connectivity growth
required for memory precision
Sarah Ruediger, Claudia Vittori, Ewa Bednarek, Christel Genoud,
Piergiorgio Strata et al.
In the adult brain, new synapses are formed and pre-existing ones are
lost, but...
http://links.ealert.nature.com/ctt?kn=104&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Improved molecular replacement by density- and energy-guided protein
structure optimization
Frank DiMaio, Thomas C. Terwilliger, Randy J. Read, Alexander Wlodawer,
Gustav Oberdorfer et al.
Molecular replacement procedures, which search for placements of a
starting mod...
http://links.ealert.nature.com/ctt?kn=103&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT
hybrids
Dawn M. Wenzel, Alexei Lissounov, Peter S. Brzovic and Rachel E. Klevit
Although the functional interaction between ubiquitin-conjugating
enzymes (E2s)...
http://links.ealert.nature.com/ctt?kn=44&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Aberrant lipid metabolism disrupts calcium homeostasis causing liver
endoplasmic reticulum stress in obesity
Suneng Fu, Ling Yang, Ping Li, Oliver Hofmann, Lee Dicker et al.
The endoplasmic reticulum (ER) is the main site of protein and
lipid synthesis,...
http://links.ealert.nature.com/ctt?kn=37&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Evolutionary biology: The origins of novelty
Armin P. Moczek
Treehoppers produce highly diverse structures called helmets. To do
so they seem to have exploited the genetic potential, long inhibited
in other winged insects, to develop wings on a particular anatomical
segment.
http://links.ealert.nature.com/ctt?kn=38&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Biochemistry: Life imitates art
Wendy L. Kelly
The biosynthetic route to a naturally occurring insecticide, spinosyn A,
has been established. One of the enzymes involved might catalyse a
reaction that, although widely used by chemists, has proved elusive
in nature.
http://links.ealert.nature.com/ctt?kn=31&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Translational medicine: To the rescue of the failing heart
Donald M. Bers and Samantha P. Harris
Heart failure is characterized by weakened contractions of heart muscle.
A drug that directly activates the key force-generating molecule in
this muscle may be a valuable tool to strengthen the failing heart.
http://links.ealert.nature.com/ctt?kn=33&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

NEWS & COMMENT
** Zoology: Jellyfish eyes on the sky
http://links.ealert.nature.com/ctt?kn=34&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Ecology: Understudy takes on tortoise's role
http://links.ealert.nature.com/ctt?kn=36&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Genomics: A guided tour of the genome
http://links.ealert.nature.com/ctt?kn=27&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Neuroscience: Monkey recalls what monkey saw
http://links.ealert.nature.com/ctt?kn=28&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Immunology: Worm-proofing the gut
http://links.ealert.nature.com/ctt?kn=29&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Metabolism: Diabetes drug affects the brain
http://links.ealert.nature.com/ctt?kn=30&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Evolutionary genetics: Hunting for birth-timing genes
http://links.ealert.nature.com/ctt?kn=56&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=79&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Q&A: Illuminating the dark
As he releases a 3D documentary about the prehistoric paintings in
Chauvet Cave in southern France, Werner Herzog -- the German director
of Fitzcarraldo and Grizzly Man -- talks about cave art and the
hostility of nature.
http://links.ealert.nature.com/ctt?kn=67&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** NIH revamp: US health care at fault
Thomas E. DeCoursey
http://links.ealert.nature.com/ctt?kn=66&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** NIH revamp: real issue is resources
Russ Altman
http://links.ealert.nature.com/ctt?kn=70&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** NIH revamp: avoid a redundant revolution
John Robinson
http://links.ealert.nature.com/ctt?kn=69&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Systems immunology: Complexity captured
Researchers who can grasp the intricacies of the immune system and
enjoy distilling meaning from large data sets are in demand for a
growing subfield of systems biology.
http://links.ealert.nature.com/ctt?kn=54&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** African spending up
Increased agricultural-science budgets are creating new research jobs
in sub-Saharan nations.
http://links.ealert.nature.com/ctt?kn=55&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** NIH spared budget slash
Federal grants won't evaporate for US biomedical researchers in 2011.
http://links.ealert.nature.com/ctt?kn=52&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Turning point: Martin Jonikas
A plant biologist has won an international grant for his work using
genetic tools to advance understanding of photosynthesis.
http://links.ealert.nature.com/ctt?kn=53&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0


** More News & Comment on BIOLOGICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=61&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0


=========================== ADVERTISEMENT ===========================
Nature Genetics in association with Anhui Medical University in China
presents:
GWAS 2011: Opportunities and Challenges
May 19-22, 2011 - Hefei city, Anhui province, China
This GWAS workshop will provide us unique insights for promoting the
current GWAS from discovery of more causal disease variants to potential
clinical application.
Register today: http://links.ealert.nature.com/ctt?kn=60&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0
=====================================================================

======================== CHEMICAL SCIENCES ========================
RESEARCH
** Crystal structure of oxygen-evolving photosystem II at a resolution
of 1.9 A
Yasufumi Umena, Keisuke Kawakami, Jian-Ren Shen and Nobuo Kamiya
Photosystem II is the site of photosynthetic water oxidation and
contains 20 su...
http://links.ealert.nature.com/ctt?kn=110&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** The Soret effect and isotopic fractionation in high-temperature
silicate melts
Gerardo Dominguez, Gautam Wilkins and Mark H. Thiemens
Diffusion in condensed phases is a ubiquitous but poorly understood
phenomenon....
http://links.ealert.nature.com/ctt?kn=50&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis
of spinosyn A
Hak Joong Kim, Mark W. Ruszczycky, Sei-hyun Choi, Yung-nan Liu and
Hung-wen Liu
The Diels-Alder reaction is a [4+2] cycloaddition reactio...
http://links.ealert.nature.com/ctt?kn=107&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT
hybrids
Dawn M. Wenzel, Alexei Lissounov, Peter S. Brzovic and Rachel E. Klevit
Although the functional interaction between ubiquitin-conjugating
enzymes (E2s)...
http://links.ealert.nature.com/ctt?kn=44&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Aberrant lipid metabolism disrupts calcium homeostasis causing
liver endoplasmic reticulum stress in obesity
Suneng Fu, Ling Yang, Ping Li, Oliver Hofmann, Lee Dicker et al.
The endoplasmic reticulum (ER) is the main site of protein and lipid
synthesis,...
http://links.ealert.nature.com/ctt?kn=37&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Biochemistry: Life imitates art
Wendy L. Kelly
The biosynthetic route to a naturally occurring insecticide, spinosyn A,
has been established. One of the enzymes involved might catalyse a
reaction that, although widely used by chemists, has proved elusive
in nature.
http://links.ealert.nature.com/ctt?kn=31&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Materials chemistry: Catalytic accordions
Nicolas Giuseppone and Jean-Francois Lutz
Single chains of a specially designed polymer fold up in water to form
an encapsulated catalytic chamber. This supramolecular assembly
strategy mimics the one used by enzymes in nature.
http://links.ealert.nature.com/ctt?kn=51&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

NEWS & COMMENT
** Organic chemistry: Fusing rings with fluorine
http://links.ealert.nature.com/ctt?kn=48&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** From isotopes to the stars
Creating more exotic isotopes will reveal the stellar formation of
atoms -- a fitting tribute to Ernest Rutherford,
say Michael Thoennessen and Bradley Sherrill.
http://links.ealert.nature.com/ctt?kn=92&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Boost for solar research
A US federal grant for photovoltaic research will create hundreds of
academic and industrial jobs.
http://links.ealert.nature.com/ctt?kn=49&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0


** More News & Comment on CHEMICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=35&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0


======================== PHYSICAL SCIENCES ========================
RESEARCH
** Single-ion quantum lock-in amplifier
Shlomi Kotler, Nitzan Akerman, Yinnon Glickman, Anna Keselman and
Roee Ozeri
Quantum metrology uses tools from quantum information science to
improve measur...
http://links.ealert.nature.com/ctt?kn=84&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Convergence of electronic bands for high performance bulk
thermoelectrics
Yanzhong Pei, Xiaoya Shi, Aaron LaLonde, Heng Wang, Lidong Chen et al.
Thermoelectric generators, which directly convert heat into
electricity, have l...
http://links.ealert.nature.com/ctt?kn=45&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** The Soret effect and isotopic fractionation in high-temperature
silicate melts
Gerardo Dominguez, Gautam Wilkins and Mark H. Thiemens
Diffusion in condensed phases is a ubiquitous but poorly understood
phenomenon....
http://links.ealert.nature.com/ctt?kn=50&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** A single-atom quantum memory
Holger P. Specht, Christian Nolleke, Andreas Reiserer, Manuel Uphoff,
Eden Figueroa et al.
The faithful storage of a quantum bit (qubit) of light is essential
for long-di...
http://links.ealert.nature.com/ctt?kn=6&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Metrology: Filtering noise with a quantum probe
John J. Bollinger
In the science of measurement, increasing the sensitivity to the
quantity being measured while minimizing the susceptibility to noise
is a challenge. A technique demonstrated with a single electron spin
may help to tackle it.
http://links.ealert.nature.com/ctt?kn=7&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Materials chemistry: Catalytic accordions
Nicolas Giuseppone and Jean-Francois Lutz
Single chains of a specially designed polymer fold up in water to form
an encapsulated catalytic chamber. This supramolecular assembly
strategy mimics the one used by enzymes in nature.
http://links.ealert.nature.com/ctt?kn=51&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

NEWS & COMMENT
** Nanotechnology: Bigger screens with nanotubes
http://links.ealert.nature.com/ctt?kn=8&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Storm warning
Political hostility over global-warming policy in the United States
is causing collateral damage. Plans for a National Climate Service
deserve better.
http://links.ealert.nature.com/ctt?kn=83&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Space science: Along for the ride
Reusable commercial rockets will soon be able to take scientists
-- and tourists -- on suborbital spaceflights. Are these vehicles
vital research tools, or an expensive dead end?
http://links.ealert.nature.com/ctt?kn=2&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** From isotopes to the stars
Creating more exotic isotopes will reveal the stellar formation of
atoms -- a fitting tribute to Ernest Rutherford,
say Michael Thoennessen and Bradley Sherrill.
http://links.ealert.nature.com/ctt?kn=92&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Technology: Together, bit by bit
A historian's insights into digital culture fascinate George Rousseau.
http://links.ealert.nature.com/ctt?kn=90&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=79&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Systems immunology: Complexity captured
Researchers who can grasp the intricacies of the immune system and
enjoy distilling meaning from large data sets are in demand for a
growing subfield of systems biology.
http://links.ealert.nature.com/ctt?kn=54&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Boost for solar research
A US federal grant for photovoltaic research will create hundreds
of academic and industrial jobs.
http://links.ealert.nature.com/ctt?kn=49&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** More News & Comment on PHYSICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=43&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0


======================== EARTH AND ENVIRONMENTAL SCIENCES ========================
RESEARCH
** The Soret effect and isotopic fractionation in high-temperature
silicate melts
Gerardo Dominguez, Gautam Wilkins and Mark H. Thiemens
Diffusion in condensed phases is a ubiquitous but poorly understood
phenomenon....
http://links.ealert.nature.com/ctt?kn=50&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Depth-dependent extension, two-stage breakup and cratonic
underplating at rifted margins
Ritske Huismans and Christopher Beaumont
Uniform lithospheric extension predicts basic properties of
non-volcanic rifted...
http://links.ealert.nature.com/ctt?kn=9&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

NEWS & COMMENT
** Oceanography: A tsunami's trip around the world
http://links.ealert.nature.com/ctt?kn=1&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Storm warning
Political hostility over global-warming policy in the United States
is causing collateral damage. Plans for a National Climate Service
deserve better.
http://links.ealert.nature.com/ctt?kn=83&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Environment: Water, water everywhere...
Margaret Catley-Carlson wonders why humanity places so little value
on its most basic resource.
http://links.ealert.nature.com/ctt?kn=88&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=79&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** UNESCO helps manage tsunamis
Irina Bokova
http://links.ealert.nature.com/ctt?kn=72&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0


** More News & Comment on EARTH AND ENVIRONMENTAL SCIENCES
http://links.ealert.nature.com/ctt?kn=42&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

=========================== ADVERTISEMENT ===========================
Nature Communications
Celebrates its 1st anniversary!
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=====================================================================


======================== CAREERS & JOBS ========================
** Systems immunology: Complexity captured
Researchers who can grasp the intricacies of the immune system and
enjoy distilling meaning from large data sets are in demand for a
growing subfield of systems biology.
http://links.ealert.nature.com/ctt?kn=121&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** African spending up
Increased agricultural-science budgets are creating new research jobs
in sub-Saharan nations.
http://links.ealert.nature.com/ctt?kn=100&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Boost for solar research
A US federal grant for photovoltaic research will create hundreds of
academic and industrial jobs.
http://links.ealert.nature.com/ctt?kn=97&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** NIH spared budget slash
Federal grants won't evaporate for US biomedical researchers in 2011.
http://links.ealert.nature.com/ctt?kn=95&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Turning point: Martin Jonikas
A plant biologist has won an international grant for his work using
genetic tools to advance understanding of photosynthesis.
http://links.ealert.nature.com/ctt?kn=93&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Storm warning
Political hostility over global-warming policy in the United States is
causing collateral damage. Plans for a National Climate Service
deserve better.
http://links.ealert.nature.com/ctt?kn=83&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** Space science: Along for the ride
Reusable commercial rockets will soon be able to take scientists
-- and tourists -- on suborbital spaceflights. Are these vehicles
vital research tools, or an expensive dead end?
http://links.ealert.nature.com/ctt?kn=22&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** NIH revamp: US health care at fault
Thomas E. DeCoursey
http://links.ealert.nature.com/ctt?kn=66&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** NIH revamp: real issue is resources
Russ Altman
http://links.ealert.nature.com/ctt?kn=70&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** NIH revamp: avoid a redundant revolution
John Robinson
http://links.ealert.nature.com/ctt?kn=69&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** UNESCO helps manage tsunamis
Irina Bokova
http://links.ealert.nature.com/ctt?kn=72&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0

** It is rational to doubt Fukushima reports
Peter M. Sandman and Jody Lanard
http://links.ealert.nature.com/ctt?kn=71&m=36580827&r=MjA1NzcwMjE4MQS2&b=2&j=MTAwNjQ3NzI5S0&mt=1&rt=0


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