Wednesday, April 6, 2011

Nature contents: 07 April 2011

Nature Alert
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View Table of Contents http://links.ealert.nature.com/ctt?kn=49&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

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Nature Immunology webcast
Current Controversies: Lineage Differentiation!
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=========================== ADVERTISEMENT ===========================
---THIS WEEK'S HIGHLIGHTS:

--Biological Sciences
-Self-organizing optic-cup morphogenesis in three-dimensional culture
Clusters of mouse stem cells organize themselves into layered structures
resembling the optic cup, a precursor of the embryonic eye, and then
form fully stratified retinal tissue. This has important implications
for regenerative medicine.
[ http://links.ealert.nature.com/ctt?kn=97&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0 ]

--Earth & Environmental Sciences
-Low strength of deep San Andreas fault gouge from SAFOD core
Laboratory strength measurements of material from a drill hole located
north-west of Parkfield, California show that the San Andreas fault
is very weak at this location and depth. The cause is an accumulation
of saponite -- one of the weakest phyllosilicate minerals known.
[ http://links.ealert.nature.com/ctt?kn=99&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0 ]

--Earth & Environmental Sciences
-Biodiversity improves water quality through niche partitioning
Experiments involving manipulation of the number of algae species
in model stream systems suggest a mechanism to explain why the
conservation of biodiversity improves the ability of an ecosystem
to retain nutrients and remain productive.
[ http://links.ealert.nature.com/ctt?kn=94&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0 ]

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--Podcast & Video
-This week, growing retinas in the lab, 50 years on since the first
human in space - and other anniversaries. Plus, the best of the
rest from Nature.
[ http://links.ealert.nature.com/ctt?kn=121&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0 ]
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======================== NEWS AND COMMENT ========================
Read daily news coverage http://links.ealert.nature.com/ctt?kn=122&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

EDITORIALS
** Scotland be brave
Those who want to build a better future for Scotland should resist
cuts to an innovative scheme that helps its universities to compete
with larger rivals elsewhere.
http://links.ealert.nature.com/ctt?kn=96&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Soya scrutiny
A partnership to encourage sustainable farming in Brazil may not be
as green as it seems.
http://links.ealert.nature.com/ctt?kn=103&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Eye on the tiger
The latest Indian tiger census demonstrates welcome methodological
rigour.
http://links.ealert.nature.com/ctt?kn=104&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

WORLD VIEW
** A long shadow over Fukushima
One impact of Japan's nuclear crisis is a dim but definite echo of
Chernobyl, says Jim Smith — decades of caesium-137.
http://links.ealert.nature.com/ctt?kn=48&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

SEVEN DAYS
** Seven days: 7 April 2011
The week in science
http://links.ealert.nature.com/ctt?kn=21&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

NEWS
** Fukushima health risks scrutinized
But scientists are struggling to pick through radiation data.
http://links.ealert.nature.com/ctt?kn=20&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Japan's long road ahead
Isotopes hint at more than a decade of clean-up at Fukushima.
http://links.ealert.nature.com/ctt?kn=19&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** US radiation study sparks debate
Researchers divided on how best to probe any possible link to cancer.
http://links.ealert.nature.com/ctt?kn=27&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** NASA human space-flight programme lost in
transition
US space agency is wrestling with competing visions and uncertainty
of budget deadlock.
http://links.ealert.nature.com/ctt?kn=26&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Rare-disease project has global ambitions
Consortium aims for hundreds of new therapies by 2020.
http://links.ealert.nature.com/ctt?kn=24&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Bulgarian funding agency accused of poor practice
Former director claims his efforts to reform National Science Fund
have been hindered.
http://links.ealert.nature.com/ctt?kn=22&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Patent dispute threatens US Alzheimer's research
Lawsuit could expose hundreds of scientists to property-rights
litigation.
http://links.ealert.nature.com/ctt?kn=31&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

FEATURES
** Materials Science: The pull of stronger magnets
Super-powerful magnets would boost the performance of electric cars
and other green technology. Why is it so hard to make them?
http://links.ealert.nature.com/ctt?kn=29&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Developing world: Educating India
The country's vast, education-hungry population could supply the next
generation of the world's scientists — but only if it can teach them.
http://links.ealert.nature.com/ctt?kn=14&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

COMMENT
** NASA: what now?
This month marks 50 years since Yuri Gagarin first ventured into space
in the Vostok 1 mission, and 30 years since NASA's first shuttle flight.
As the shuttle Endeavour prepares for its final flight, seven experts
outline what NASA's priorities need to be.
http://links.ealert.nature.com/ctt?kn=100&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** The search for clean cash
The Massachusetts Institute of Technology has been an innovator of
university funding models, says David Kaiser. Its 150-year history
holds lessons for today.
http://links.ealert.nature.com/ctt?kn=102&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Fix the antibiotics pipeline
As resistance mushrooms, governments must make development of new
antibiotics financially viable for industry,
say Matthew A. Cooper and David Shlaes.
http://links.ealert.nature.com/ctt?kn=92&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

BOOKS AND ARTS
** Psychology: The art of remembering
Larry R. Squire enjoys an engaging account of how memory works and
how to win in memory competitions.
http://links.ealert.nature.com/ctt?kn=80&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Globalization: Behind India's technological boom
The rise of outsourcing by Western companies stifles local innovation,
learns Andrew Robinson.
http://links.ealert.nature.com/ctt?kn=79&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=83&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Astronomy: Finding other worlds
A survey of exoplanetary research shows how the field has come in
from the cold, finds Chris Tinney.
http://links.ealert.nature.com/ctt?kn=82&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Communication: Show and tell
A New York storytelling project reveals the personal side of
scientific life, finds David Carmel.
http://links.ealert.nature.com/ctt?kn=85&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

CORRESPONDENCE
** China's green policy has some way to go
Tong Wu
http://links.ealert.nature.com/ctt?kn=84&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** An insight into Maxwell's mind?
David J. Tyler
http://links.ealert.nature.com/ctt?kn=87&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Financial model failed in real world
Robin O. Motz
http://links.ealert.nature.com/ctt?kn=86&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Shuttle programme lifetime cost
Roger Pielke, Jr and Radford Byerly
http://links.ealert.nature.com/ctt?kn=116&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0


=========================== ADVERTISEMENT ===========================
Nominations are being solicited for the 2011 J. Allyn Taylor
International Prize in Medicine. The Prize will be awarded to a
scientist who has made outstanding contributions in the area of Stem
Cell Research. Nominations should be sent prior to May 1st, 2011.

http://links.ealert.nature.com/ctt?kn=56&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0
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======================== BIOLOGICAL SCIENCES ========================
RESEARCH
** Self-organizing optic-cup morphogenesis in three-dimensional culture
Mototsugu Eiraku, Nozomu Takata, Hiroki Ishibashi, Masako Kawada,
Eriko Sakakura et al.
Balanced organogenesis requires the orchestration of multiple
cellular interact...
http://links.ealert.nature.com/ctt?kn=97&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Gut flora metabolism of phosphatidylcholine promotes cardiovascular
disease
Zeneng Wang, Elizabeth Klipfell, Brian J. Bennett, Robert Koeth,
Bruce S. Levison et al.
Metabolomics studies hold promise for the discovery of pathways
linked to disea...
http://links.ealert.nature.com/ctt?kn=117&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Streptococcal M1 protein constructs a pathological host fibrinogen
network
Pauline Macheboeuf, Cosmo Buffalo, Chi-yu Fu, Annelies S. Zinkernagel,
Jason N. Cole et al.
M1 protein, a major virulence factor of the leading invasive strain of
group A ...
http://links.ealert.nature.com/ctt?kn=101&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Biodiversity improves water quality through niche partitioning
Bradley J. Cardinale
Excessive nutrient loading of water bodies is a leading cause of water
pollution...
http://links.ealert.nature.com/ctt?kn=94&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Tumour evolution inferred by single-cell sequencing
Nicholas Navin, Jude Kendall, Jennifer Troge, Peter Andrews,
Linda Rodgers et al.
Genomic analysis provides insights into the role of copy number
variation in di...
http://links.ealert.nature.com/ctt?kn=110&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Molecular regulation of sexual preference revealed by genetic studies
of 5-HT in the brains of male mice
Yan Liu, Yun'ai Jiang, Yunxia Si, Ji-Young Kim, Zhou-Feng Chen et al.
Although the question of to whom a male directs his mating attempts is
a critic...
http://links.ealert.nature.com/ctt?kn=107&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Local, persistent activation of Rho GTPases during plasticity of
single dendritic spines
Hideji Murakoshi, Hong Wang and Ryohei Yasuda
The Rho family of GTPases have important roles in the morphogenesis
of the dend...
http://links.ealert.nature.com/ctt?kn=106&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Dampening of death pathways by schnurri-2 is essential for T-cell
development
Tracy L. Staton, Vanja Lazarevic, Dallas C. Jones, Amanda J. Lanser,
Tsuyoshi Takagi et al.
Generation of a diverse and self-tolerant T-cell repertoire requires
appropriat...
http://links.ealert.nature.com/ctt?kn=105&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Hedgehog/Wnt feedback supports regenerative proliferation of
epithelial stem cells in bladder
Kunyoo Shin, John Lee, Nini Guo, James Kim, Agnes Lim et al.
Epithelial integrity in metazoan organs is maintained through the
regulated pro...
http://links.ealert.nature.com/ctt?kn=115&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** An siRNA pathway prevents transgenerational retrotransposition in
plants subjected to stress
Hidetaka Ito, Herve Gaubert, Etienne Bucher, Marie Mirouze,
Isabelle Vaillant et al.
Eukaryotic genomes consist to a significant extent of retrotransposons
that are...
http://links.ealert.nature.com/ctt?kn=113&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** A long noncoding RNA maintains active chromatin to coordinate
homeotic gene expression
Kevin C. Wang, Yul W. Yang, Bo Liu, Amartya Sanyal,
Ryan Corces-Zimmerman et al.
The genome is extensively transcribed into long intergenic noncoding
RNAs (linc...
http://links.ealert.nature.com/ctt?kn=112&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Crystal structure of a phosphorylation-coupled saccharide transporter
Yu Cao, Xiangshu Jin, Elena J. Levin, Hua Huang, Yinong Zong et al.
Saccharides have a central role in the nutrition of all living
organisms. Where...
http://links.ealert.nature.com/ctt?kn=111&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** DISC1-dependent switch from progenitor proliferation to migration
in the developing cortex
Koko Ishizuka, Atsushi Kamiya, Edwin C. Oh, Hiroaki Kanki,
Saurav Seshadri et al.
Regulatory mechanisms governing the sequence from progenitor cell
proliferation...
http://links.ealert.nature.com/ctt?kn=53&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Eutherian mammals use diverse strategies to initiate X-chromosome
inactivation during development
Ikuhiro Okamoto, Catherine Patrat, Dominique Thepot, Nathalie Peynot,
Patricia Fauque et al.
X-chromosome inactivation (XCI) in female mammals allows dosage
compensation fo...
http://links.ealert.nature.com/ctt?kn=44&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Suppression of lung adenocarcinoma progression by Nkx2-1
Monte M. Winslow, Talya L. Dayton, Roel G. W. Verhaak,
Caroline Kim-Kiselak, Eric L. Snyder et al.
Despite the high prevalence and poor outcome of patients with
metastatic lung c...
http://links.ealert.nature.com/ctt?kn=45&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Increasing adult hippocampal neurogenesis is sufficient to improve
pattern separation
Amar Sahay, Kimberly N. Scobie, Alexis S. Hill, Colin M. O'Carroll,
Mazen A. Kheirbek et al.
Adult hippocampal neurogenesis is a unique form of neural circuit
plasticity th...
http://links.ealert.nature.com/ctt?kn=38&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Neuronal activity is required for the development of specific
cortical interneuron subtypes
Natalia V. De Marco Garcia, Theofanis Karayannis and Gord Fishell
Electrical activity has been shown to regulate development in a variety
of spec...
http://links.ealert.nature.com/ctt?kn=40&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Genome-wide analysis reveals novel molecular features of mouse
recombination hotspots
Fatima Smagulova, Ivan V. Gregoretti, Kevin Brick, Pavel Khil,
R. Daniel Camerini-Otero et al.
Meiotic recombination predominantly occurs at discrete genomic loci
called reco...
http://links.ealert.nature.com/ctt?kn=41&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Ephrin Bs are essential components of the Reelin pathway to regulate
neuronal migration
Aycan Senturk, Sylvia Pfennig, Alexander Weiss, Katja Burk and
Amparo Acker-Palmer
Coordinated migration of neurons in the developing and adult brain
is essential...
http://links.ealert.nature.com/ctt?kn=43&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and
during differentiation
Gabriella Ficz, Miguel R. Branco, Stefanie Seisenberger, Fatima Santos,
Felix Krueger et al.
Methylation at the 5[prime] position of cytosine in DNA has important
roles i...
http://links.ealert.nature.com/ctt?kn=34&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Cardiovascular disease: The diet-microbe morbid union
Kimberly Rak and Daniel J. Rader
A common dietary component that some people even take as a supplement
is converted by the gut microbiota to harmful metabolites linked to
heart disease. This finding has cautionary implications.
http://links.ealert.nature.com/ctt?kn=35&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Regenerative medicine: DIY eye
Robin R. Ali and Jane C. Sowden
Generation of complex organs in vitro is a major challenge in
regenerative medicine. But it is not an impossible one: an entire
synthetic retina has now been generated from embryonic stem cells.
http://links.ealert.nature.com/ctt?kn=36&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Ecology: Diversity favours productivity
Andy Hector
A consequence of Darwin's 'principle of divergence' is that loss of
species can harm the functioning of ecosystems. A study of algal
communities in artificial streams suggests that he was right.
http://links.ealert.nature.com/ctt?kn=37&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Reproductive biology: Bone returns the favour
Sonya M. Schuh-Huerta and Renee A. Reijo Pera
There are well-established links between the reproductive system,
metabolism and skeletal growth. But it comes as a surprise that the
skeleton -- more specifically, the bone hormone osteocalcin -- modulates
fertility.
http://links.ealert.nature.com/ctt?kn=67&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

NEWS & COMMENT
** Cancer biology: Malaria drug shrinks tumours
http://links.ealert.nature.com/ctt?kn=65&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Palaeoanthropology: Remains in ancient cave get younger
http://links.ealert.nature.com/ctt?kn=66&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Evolutionary biology: Bad for your teeth?
http://links.ealert.nature.com/ctt?kn=63&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Palaeontology: The giant rabbits of Minorca
http://links.ealert.nature.com/ctt?kn=64&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Cell biology: Starved cells opt for quiescence
http://links.ealert.nature.com/ctt?kn=61&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Eye on the tiger
The latest Indian tiger census demonstrates welcome methodological rigour.
http://links.ealert.nature.com/ctt?kn=104&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Fix the antibiotics pipeline
As resistance mushrooms, governments must make development of new
antibiotics financially viable for industry,
say Matthew A. Cooper and David Shlaes.
http://links.ealert.nature.com/ctt?kn=92&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Psychology: The art of remembering
Larry R. Squire enjoys an engaging account of how memory works and how
to win in memory competitions.
http://links.ealert.nature.com/ctt?kn=80&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** California: Safe harbour
San Diego's diverse corporate science portfolio offers opportunities
for open-minded scientists hoping to escape stagnation in academia.
http://links.ealert.nature.com/ctt?kn=62&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0


** More News & Comment on BIOLOGICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=73&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0


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Nature Special: Japan earthquake and nuclear crisis

Nature brings you regular updates on the crisis, as well as analysis
of why this earthquake was so destructive, the Japanese government's
struggle to respond to the nuclear disaster, and the effects on Japan's
research community.

Bookmark this Special for the latest news and developments.
http://links.ealert.nature.com/ctt?kn=54&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0
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======================== CHEMICAL SCIENCES ========================
RESEARCH
** Streptococcal M1 protein constructs a pathological host fibrinogen
network
Pauline Macheboeuf, Cosmo Buffalo, Chi-yu Fu, Annelies S. Zinkernagel,
Jason N. Cole et al.
M1 protein, a major virulence factor of the leading invasive strain
of group A ...
http://links.ealert.nature.com/ctt?kn=101&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

NEWS & COMMENT
** Chemistry: Fine-tuning polymerization
http://links.ealert.nature.com/ctt?kn=59&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0


** More News & Comment on CHEMICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=42&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0


======================== PHYSICAL SCIENCES ========================
RESEARCH
** Electromagnetically induced transparency and slow light with
optomechanics
A. H. Safavi-Naeini, T. P. Mayer Alegre, J. Chan, M. Eichenfield,
M. Winger et al.
Controlling the interaction between localized optical and mechanical
excitation...
http://links.ealert.nature.com/ctt?kn=60&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** High-frequency, scaled graphene transistors on diamond-like carbon
Yanqing Wu, Yu-ming Lin, Ageeth A. Bol, Keith A. Jenkins,
Fengnian Xia et al.
Owing to its high carrier mobility and saturation velocity, graphene
has attrac...
http://links.ealert.nature.com/ctt?kn=55&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Genome-wide analysis reveals novel molecular features of mouse
recombination hotspots
Fatima Smagulova, Ivan V. Gregoretti, Kevin Brick, Pavel Khil,
R. Daniel Camerini-Otero et al.
Meiotic recombination predominantly occurs at discrete genomic loci
called reco...
http://links.ealert.nature.com/ctt?kn=41&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Electronics: Industry-compatible graphene transistors
Frank Schwierz
An innovative technique has been developed to manufacture graphene
transistors that operate at radio frequencies and low temperatures.
The process brings the devices closer to applications.
http://links.ealert.nature.com/ctt?kn=9&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Oceanography: When glacial giants roll over
Anders Levermann
The energy released by capsizing icebergs can be equal to that of
small earthquakes -- enough to create ocean waves of considerable
magnitude. Should such 'glacial tsunamis' be added to the list of
future global-warming hazards?
http://links.ealert.nature.com/ctt?kn=10&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Cosmology: A smoother end to the dark ages
Zoltan Haiman
Independent lines of evidence suggest that the first stars, which
ended the cosmic dark ages, came in pairs rather than singly. This
could change the prevailing view that the early Universe had a
Swiss-cheese-like appearance.
http://links.ealert.nature.com/ctt?kn=11&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

NEWS & COMMENT
** Origami: How to fold a rigid bag
http://links.ealert.nature.com/ctt?kn=13&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Nanotechnology: Painting and shaping pillars
http://links.ealert.nature.com/ctt?kn=1&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Astronomy: Comets gave rings their ripples
http://links.ealert.nature.com/ctt?kn=2&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Fluid dynamics: Getting through a drowning machine
http://links.ealert.nature.com/ctt?kn=4&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Scotland be brave
Those who want to build a better future for Scotland should resist
cuts to an innovative scheme that helps its universities to compete
with larger rivals elsewhere.
http://links.ealert.nature.com/ctt?kn=96&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** NASA: what now?
This month marks 50 years since Yuri Gagarin first ventured into
space in the Vostok 1 mission, and 30 years since NASA's first shuttle
flight. As the shuttle Endeavour prepares for its final flight, seven
experts outline what NASA's priorities need to be.
http://links.ealert.nature.com/ctt?kn=100&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Globalization: Behind India's technological boom
The rise of outsourcing by Western companies stifles local innovation,
learns Andrew Robinson.
http://links.ealert.nature.com/ctt?kn=79&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=83&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Astronomy: Finding other worlds
A survey of exoplanetary research shows how the field has come in
from the cold, finds Chris Tinney.
http://links.ealert.nature.com/ctt?kn=82&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** An insight into Maxwell's mind?
David J. Tyler
http://links.ealert.nature.com/ctt?kn=87&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Shuttle programme lifetime cost
Roger Pielke, Jr and Radford Byerly
http://links.ealert.nature.com/ctt?kn=116&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0


** More News & Comment on PHYSICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=52&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0


======================== EARTH AND ENVIRONMENTAL SCIENCES ========================
RESEARCH
** Evidence for mechanical coupling and strong Indian lower crust
beneath southern Tibet
Alex Copley, Jean-Philippe Avouac and Brian P. Wernicke
How surface deformation within mountain ranges relates to tectonic
processes at...
http://links.ealert.nature.com/ctt?kn=5&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Low strength of deep San Andreas fault gouge from SAFOD core
David A. Lockner, Carolyn Morrow, Diane Moore and Stephen Hickman
The San Andreas fault accommodates 28-34 mm yr-1...
http://links.ealert.nature.com/ctt?kn=99&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Biodiversity improves water quality through niche partitioning
Bradley J. Cardinale
Excessive nutrient loading of water bodies is a leading cause of
water pollutio...
http://links.ealert.nature.com/ctt?kn=94&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Thermal history of Mars inferred from orbital geochemistry of
volcanic provinces
David Baratoux, Michael J. Toplis, Marc Monnereau and Olivier Gasnault
Reconstruction of the geological history of Mars has been the focus
of consider...
http://links.ealert.nature.com/ctt?kn=6&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Isotope fractionation in silicate melts by thermal diffusion
Frank M. Richter
Arising from F. Huang, P. et al. Nature 464, 396-400 (2010); Huang et al.
It was recently shown that relatively large (compared to analytical
precision) ...
http://links.ealert.nature.com/ctt?kn=7&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Huang et al. reply
F. Huang, P. Chakraborty, C. C. Lundstrom, C. Holmden,
J. J. G. Glessner et al.
Replying to F. M. Richter...
http://links.ealert.nature.com/ctt?kn=23&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Oceanography: When glacial giants roll over
Anders Levermann
The energy released by capsizing icebergs can be equal to that of small
earthquakes -- enough to create ocean waves of considerable magnitude.
Should such 'glacial tsunamis' be added to the list of future
global-warming hazards?
http://links.ealert.nature.com/ctt?kn=10&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Ecology: Diversity favours productivity
Andy Hector
A consequence of Darwin's 'principle of divergence' is that loss of
species can harm the functioning of ecosystems. A study of algal
communities in artificial streams suggests that he was right.
http://links.ealert.nature.com/ctt?kn=37&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Earth science: A new mechanical model for Tibet
Jeffrey T. Freymueller
A three-dimensional mechanical model of the Tibetan crust explains both
the first-order features of GPS surface velocities and the contrast
in the types of earthquake between northern and southern Tibet.
http://links.ealert.nature.com/ctt?kn=28&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

NEWS & COMMENT
** Soya scrutiny
A partnership to encourage sustainable farming in Brazil may not be
as green as it seems.
http://links.ealert.nature.com/ctt?kn=103&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Eye on the tiger
The latest Indian tiger census demonstrates welcome methodological rigour.
http://links.ealert.nature.com/ctt?kn=104&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** NASA: what now?
This month marks 50 years since Yuri Gagarin first ventured into
space in the Vostok 1 mission, and 30 years since NASA's first shuttle
flight. As the shuttle Endeavour prepares for its final flight, seven
experts outline what NASA's priorities need to be.
http://links.ealert.nature.com/ctt?kn=100&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=83&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Astronomy: Finding other worlds
A survey of exoplanetary research shows how the field has come in
from the cold, finds Chris Tinney.
http://links.ealert.nature.com/ctt?kn=82&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** China's green policy has some way to go
Tong Wu
http://links.ealert.nature.com/ctt?kn=84&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0


** More News & Comment on EARTH AND ENVIRONMENTAL SCIENCES
http://links.ealert.nature.com/ctt?kn=51&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

=========================== ADVERTISEMENT ===========================
Herrenhausen Symposium on Autoimmunity
June 20-23, 2011 • Kloster Seeon, Seeon, Germany
A subset of leaders in the field will attend the Herrenhausen
Symposium and participate in an interdisciplinary discussion that
will point in the direction of solutions to the greatest challenges
that the field of autoimmunity faces.
Application deadline - April 22, 2011
http://links.ealert.nature.com/ctt?kn=70&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0
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======================== CAREERS & JOBS ========================
** California: Safe harbour
San Diego's diverse corporate science portfolio offers opportunities
for open-minded scientists hoping to escape stagnation in academia.
http://links.ealert.nature.com/ctt?kn=127&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Waiting for the motivation fairy
It's easy to give in to procrastination -- but Hugh Kearns and
Maria Gardiner offer some tips for getting your drive back.
http://links.ealert.nature.com/ctt?kn=108&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Scotland be brave
Those who want to build a better future for Scotland should resist
cuts to an innovative scheme that helps its universities to compete
with larger rivals elsewhere.
http://links.ealert.nature.com/ctt?kn=96&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Developing world: Educating India
The country's vast, education-hungry population could supply the next
generation of the world's scientists — but only if it can teach them.
http://links.ealert.nature.com/ctt?kn=14&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** The search for clean cash
The Massachusetts Institute of Technology has been an innovator of
university funding models, says David Kaiser. Its 150-year history
holds lessons for today.
http://links.ealert.nature.com/ctt?kn=102&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0

** Globalization: Behind India's technological boom
The rise of outsourcing by Western companies stifles local innovation,
learns Andrew Robinson.
http://links.ealert.nature.com/ctt?kn=79&m=36469108&r=MjA1NzcwMjE4MQS2&b=2&j=OTg0ODgyMjkS1&mt=1&rt=0


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