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Here is your customized Science X Newsletter for March 31, 2019:
Spotlight Stories Headlines
Astronomy & Space news
 | US boots on the Moon in 2024? It won't be easyFor the past 15 years, America has sought to put its astronauts back on the Moon, but NASA did not think it could be done before 2028. |
Technology news
 | Apple pulls plug on AirPower wireless charging matApple confirmed on Friday that it will not deliver on its promise of helping usher in a wireless future with an AirPower mat for charging its devices. |
 | Stacking boxes is spectator treat if Boston Dynamics is in the warehouseEach time news breaks of a fresh video from Boston Dynamics one expects yet another fright night of bipeds making the earth tremble and doing a somersault or four for encores. |
 | No AI in humor: R2-D2 walks into a bar, doesn't get the jokeA robot walks into a bar. It goes CLANG. |
 | Magento commerce platform has fixes, users told to install asapPatches for an ecommerce platform should be applied immediately. No ifs, maybes, buts, laters. Researchers say anyone using the Magento platform should upgrade as soon as possible and in light of the threat, as soon as possible means right now. |
 | Financial pressure mounts to fix Boeing's troubled jetlinerBoeing is facing mounting pressure to roll out a software update on its best-selling plane in time for airlines to use the jets during the peak summer travel season. |
 | New Australian laws could see social media execs jailed over terror imagesAustralia pledged Saturday to introduce new laws that could see social media executives jailed and tech giants fined billions for failing to remove extremist material from their platforms. |
 | Facebook to tighten live stream access after mosque attacksFacebook on Friday said it is tightening live video streaming rules in response to the service being used to broadcast deadly attacks on mosques in New Zealand. |
Breaking up Big Tech not the answer: EU commissionerBreaking up the world's tech titans is not the best way to counter their power, EU Competition Commissioner Margrethe Vestager said Friday, while leaving room for that eventuality as a "last resort." | |
 | How Europe is faring on renewable energy targetsThe European Union's use of renewable energy—such as hydropower, wind and solar—reached 17.5 percent in 2017, keeping it on track for a target of 20 percent by 2020. |
 | Facebook chief wants 'more active' govt role regulating internetFacebook chief Mark Zuckerberg called Saturday for governments to play a "more active role" in regulating the internet, urging more countries to adopt versions of sweeping European rules aimed at safeguarding user privacy. |
 | Leaders hint Poland will not fully apply EU copyright lawPoland's right-wing leaders hinted Saturday they will not fully implement the European Union's new copyright reform, saying it stifles freedom of speech. |
Medicine & Health news
 | Trips to the toilet at night are a sign of high blood pressureTrips to the toilet at night are a sign of high blood pressure, according to results from the Watari study presented today at the 83rd Annual Scientific Meeting of the Japanese Circulation Society (JCS 2019). |
Gastrointestinal complaints in children could signal future mental health problemsA Columbia University study has found that adversity early in life is associated with increased gastrointestinal symptoms in children that may have an impact on the brain and behavior as they grow to maturity. | |
 | Hundreds vaccinated after measles emergency in New YorkA New York county which declared a state of emergency over a measles outbreak is on the "right path" after administering hundreds of vaccinations in two days, the chief of the US district said on Friday. |
Immune checkpoint inhibitor combo efficacious for patients with neuroendocrine carcinomaA combination of the anti-CTLA-4 immunotherapeutic ipilimumab (Yervoy) and the anti-PD-1 immunotherapeutic nivolumab (Opdivo) showed clinical benefit among patients with rare, high-grade neuroendocrine carcinoma, according to results from the DART phase II clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. | |
HER2-targeted CAR T-cell therapy shows promising antitumor activity in patients with sarcomaA combination of chemotherapy and chimeric antigen receptor (CAR) T cells designed to target the protein HER2 was found to be safe and showed clinical responses in pediatric and adult patients with advanced HER2-positive sarcoma, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. | |
Adding savolitinib to osimertinib beneficial for certain pretreated lung cancer patientsAdding the investigational MET inhibitor savolitinib to the EGFR inhibitor osimertinib (Tagrisso) yielded clinical responses in patients who had EGFR-mutant non-small cell lung cancer (NSCLC) that had developed resistance to prior EGFR-targeted therapies through MET-gene amplification, according to interim results from two expansion cohorts of the phase Ib clinical trial TATTON, presented at the AACR Annual Meeting 2019, March 29-April 3. | |
Mesothelin-targeted CAR T-cell therapy shows early promise in patients with solid tumorsA chimeric antigen receptor (CAR) T-cell therapy that targets the protein mesothelin showed no evidence of major toxicity and had antitumor activity in patients with malignant pleural disease from mesothelioma, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. | |
 | CD40 combination therapy can shrink pancreatic tumorsA new combination of immunotherapy and chemotherapy for pancreatic cancer caused tumors to shrink in the majority of evaluable patients—20 out of 24 as of an interim analysis of the phase 1b trial data. The early findings provide hope that this strategy involving a CD40 antibody, a checkpoint inhibitor, and standard-of-care chemotherapy could be effective for treating the nation's third deadliest type of cancer. Researchers from the Abramson Cancer Center at the University of Pennsylvania will present the findings today in a clinical trials plenary session at the American Association for Cancer Research 2019 Annual Meeting in Atlanta (Abstract #8060). The ongoing study is being conducted in collaboration with the Parker Institute for Cancer Immunotherapy and its other member institutions and partners. These are the first clinical trial data ever presented as a result of this collaboration. |
Excess body weight before 50 is associated with higher risk of dying from pancreatic cancerExcess weight before age 50 may be more strongly associated with pancreatic cancer mortality risk than excess weight at older ages, according to results of a study presented at the AACR Annual Meeting 2019, March 29-April 3. | |
New glioblastoma vaccine shows promising results in phase Ib clinical trialGlioblastoma is the most aggressive type of primary brain cancer, one with a prognosis of 11-15 months with standard treatment. Results from a phase 1b clinical trial of a new experimental glioblastoma vaccine developed by Jefferson and Imvax, show the treatment was tolerated well by patients, slowed tumor recurrence, and prolonged patient survival. | |
 | Mozambique says cholera cases up to 271 in cyclone-hit cityMozambican authorities say the number of cholera cases among cyclone survivors has risen to 271. |
 | International aid helps Mozambique fight cholera in BeiraAs Mozambique battles to control a fast-spreading cholera outbreak in the cyclone-hit central city of Beira, international assistance is arriving. |
Biology news
 | Bait crisis could take the steam out of lobster this summerThe boom times for the U.S. lobster industry are imperiled this year because of a shortage of a little fish that has been luring the crustaceans into traps for hundreds of years. |
 | Sheep nibble Madrid's largest park into shapeIt's a rustic scene: sheep graze placidly on grass as a shepherd keeps watch. But this is Madrid's largest public park, not the tranquil countryside. |
 | Stranded baby elephants rescued by Thai rangersSix baby elephants separated from their parents and trapped in a muddy pit for days have been rescued by park rangers in rural Thailand, officials said Saturday. |
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