TABLE OF CONTENTS
|  | | | | Volume 117, Issue 5 (597-756)
Published online 22 August 2017
|  | In this issue
 Clinical Studies
Translational Therapeutics
Molecular Diagnostics
Genetics & Genomics
Epidemiology
Corrigenda
Also new today
 Advance online publication
Digital Edition
| | | | | | Advertisement | | New web focus from BJC: Tumour microenvironment
The tumour microenvironment (TME) comprises the spectrum of non-neoplastic cells (for example, fibroblasts and immune/inflammatory cells), vessels and associated matrix contained within a cancer. Far from being just a passive scaffold, it is now well established that the two-way interaction between these stromal components and the tumour cells themselves plays an active, and in many cases crucial, role in modulating tumour growth (through both stimulatory and inhibitory actions).
David Wynford-Thomas has put together a special collection of papers on TME >>> | | | | | | Clinical Studies | Top | | Knowledge or noise? Making sense of General Practitioners’ and Consultant use of 2-week-wait referrals for suspected cancer Conan Donnelly, Nigel Hart, Alan David McCrorie, Lesley Anderson, Michael Donnelly, Peter Murchie and Anna Gavin Br J Cancer 2017 117: 597-603; advance online publication, July 27, 2017; 10.1038/bjc.2017.213 Abstract | Full Text | | | | Long-term outcomes of patients with 10 or more colorectal liver metastases M A Allard, R Adam, F Giuliante, R Lapointe, C Hubert, J N M Ijzermans, D F Mirza, D Elias, C Laurent, T Gruenberger, G Poston, C Letoublon, H Isoniemi, V Lucidi, I Popescu and J Figueras Br J Cancer 2017 117: 604-611; advance online publication, July 20, 2017; 10.1038/bjc.2017.218 Abstract | Full Text | | | | Hamburg-Glasgow classification: preoperative staging by combination of disseminated tumour load and systemic inflammation in oesophageal carcinoma Matthias Reeh, Tarik Ghadban, Faik G Uzunoglu, Michael F Nentwich, Maximilian Bockhorn, Klaus Pantel, Jakob R Izbicki and Yogesh K Vashist Br J Cancer 2017 117: 612-618; advance online publication, July 13, 2017; 10.1038/bjc.2017.219 Abstract | Full Text | | | | The cost-effectiveness of screening for ovarian cancer: results from the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) Usha Menon, Alistair J McGuire, Maria Raikou, Andy Ryan, Susan K Davies, Matthew Burnell, Aleksandra Gentry-Maharaj, Jatinderpal K Kalsi, Naveena Singh, Nazar N Amso, Derek Cruickshank, Stephen Dobbs, Keith Godfrey, Jonathan Herod, Simon Leeson, Tim Mould, John Murdoch, David Oram, Ian Scott, Mourad W Seif, Karin Williamson, Robert Woolas, Lesley Fallowfield, Stuart Campbell, Steven J Skates, Mahesh Parmar and Ian J Jacobs Br J Cancer 2017 117: 619-627; advance online publication, July 25, 2017; 10.1038/bjc.2017.222 Abstract | Full Text | | Translational Therapeutics | Top | | Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models Cristina Belgiovine, Ezia Bello, Manuela Liguori, Ilaria Craparotta, Laura Mannarino, Lara Paracchini, Luca Beltrame, Sergio Marchini, Carlos M Galmarini, Alberto Mantovani, Roberta Frapolli, Paola Allavena and Maurizio D'Incalci Br J Cancer 2017 117: 628-638; advance online publication, July 6, 2017; 10.1038/bjc.2017.205 Abstract | Full Text | | | | HMGA1 expression levels are elevated in pancreatic intraepithelial neoplasia cells in the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer Michelle J Veite-Schmahl, William C Joesten and Michael A Kennedy Br J Cancer 2017 117: 639-647; advance online publication, July 11, 2017; 10.1038/bjc.2017.216 Abstract | Full Text | | | | Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients Roopma Wadhwa, Xuemei Wang, Veerabhadran Baladandayuthapani, Bin Liu, Hironori Shiozaki, Yusuke Shimodaira, Quan Lin, Elena Elimova, Wayne L Hofstetter, Stephen G Swisher, David C Rice, Dipen M Maru, Neda Kalhor, Manoop S Bhutani, Brian Weston, Jeffrey H Lee, Heath D Skinner, Ailing W Scott, Dilsa Mizrak Kaya, Kazuto Harada, Donald Berry, Shumei Song and Jaffer A Ajani Br J Cancer 2017 117: 648-655; advance online publication, July 20, 2017; 10.1038/bjc.2017.225 Abstract | Full Text | | | | TCTP as a therapeutic target in melanoma treatment M Boia-Ferreira, A B Basílio, A E Hamasaki, F H Matsubara, M H Appel, C R V Da Costa, R Amson, A Telerman, O M Chaim, S S Veiga and A Senff-Ribeiro Br J Cancer 2017 117: 656-665; advance online publication, July 27, 2017; 10.1038/bjc.2017.230 Abstract | Full Text | | Molecular Diagnostics | Top | | A combined biomarker panel shows improved sensitivity for the early detection of ovarian cancer allowing the identification of the most aggressive type II tumours Matthew R Russell, Ciaren Graham, Alfonsina D'Amato, Aleksandra Gentry-Maharaj, Andy Ryan, Jatinderpal K Kalsi, Carol Ainley, Anthony D Whetton, Usha Menon, Ian Jacobs and Robert L J Graham Br J Cancer 2017 117: 666-674; advance online publication, June 29, 2017; 10.1038/bjc.2017.199 Abstract | Full Text | | | | RBM38 is involved in TGF-β-induced epithelial-to-mesenchymal transition by stabilising zonula occludens-1 mRNA in breast cancer Jing Wu, Xu-Jie Zhou, Xi Sun, Tian-Song Xia, Xiao-Xia Li, Liang Shi, Lei Zhu, Wen-Bin Zhou, Ji-Fu Wei and Qiang Ding Br J Cancer 2017 117: 675-684; advance online publication, July 6, 2017; 10.1038/bjc.2017.204 Abstract | Full Text | | | | The TGF-β signalling negative regulator PICK1 represses prostate cancer metastasis to bone Yuhu Dai, Dong Ren, Qing Yang, Yanmei Cui, Wei Guo, Yingrong Lai, Hong Du, Chuyong Lin, Jun Li, Libing Song and Xinsheng Peng Br J Cancer 2017 117: 685-694; advance online publication, July 11, 2017; 10.1038/bjc.2017.212 Abstract | Full Text | | | | Platelet releasate promotes breast cancer growth and angiogenesis via VEGF–integrin cooperative signalling Lei Jiang, Yun Luan, Xinyan Miao, Chao Sun, Kailin Li, Zhangsen Huang, Dawei Xu, Mingxiang Zhang, Feng Kong and Nailin Li Br J Cancer 2017 117: 695-703; advance online publication, July 11, 2017; 10.1038/bjc.2017.214 Abstract | Full Text | | | | Correlation between circulating mutant DNA and metabolic tumour burden in advanced non-small cell lung cancer patients Anne Winther-Larsen, Christina Demuth, Joan Fledelius, Anne Tranberg Madsen, Karin Hjorthaug, Peter Meldgaard and Boe Sandahl Sorensen Br J Cancer 2017 117: 704-709; advance online publication, July 6, 2017; 10.1038/bjc.2017.215 Abstract | Full Text | | Genetics & Genomics | Top | | A comparative study of germline BRCA1 and BRCA2 mutation screening methods in use in 20 European clinical diagnostic laboratories Gillian Ellison, Andrew Wallace, Alexander Kohlmann and Simon Patton Br J Cancer 2017 117: 710-716; advance online publication, July 27, 2017; 10.1038/bjc.2017.223 Abstract | Full Text | | | | Whole-genome sequencing revealed novel prognostic biomarkers and promising targets for therapy of ovarian clear cell carcinoma Hiroaki Itamochi, Tetsuro Oishi, Nao Oumi, Satoshi Takeuchi, Kosuke Yoshihara, Mikio Mikami, Nobuo Yaegashi, Yasuhisa Terao, Kazuhiro Takehara, Kimio Ushijima, Hidemichi Watari, Daisuke Aoki, Tadashi Kimura, Toshiaki Nakamura, Yoshihito Yokoyama, Junzo Kigawa and Toru Sugiyama Br J Cancer 2017 117: 717-724; advance online publication, July 20, 2017; 10.1038/bjc.2017.228 Abstract | Full Text | | | | Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma Sarah Schumacher, Christoph Bartenhagen, Martin Hoffmann, Daniel Will, Johannes C Fischer, Stephan E Baldus, Christian Vay, Georg Fluegen, Levent Dizdar, Daniel Vallböhmer, Christoph A Klein, Wolfram T Knoefel, Nikolas H Stoecklein and Birte Möhlendick Br J Cancer 2017 117: 725-733; advance online publication, July 20, 2017; 10.1038/bjc.2017.233 Abstract | Full Text | | Epidemiology | Top | | Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium Artitaya Lophatananon, Sarah Stewart-Brown, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch Garcia, David E Neal, Freddie C Hamdy, Jenny L Donovan, Graham G Giles, Liesel M Fitzgerald, Melissa C Southey, Paul Pharoah, Nora Pashayan, Henrik Gronberg, Fredrik Wiklund, Markus Aly, Janet L Stanford, Hermann Brenner, Aida K Dieffenbach, Volker Arndt, Jong Y Park, Hui-Yi Lin, Thomas Sellers, Chavdar Slavov, Radka Kaneva, Vanio Mitev, Jyotsna Batra, Amanda Spurdle, Judith A Clements, APCB BioResource, The PRACTICAL consortium, Douglas Easton, Rosalind A Eeles and Kenneth Muir Br J Cancer 2017 117: 734-743; advance online publication, August 1, 2017; 10.1038/bjc.2017.231 Abstract | Full Text | | | | Lung cancer prognostic index: a risk score to predict overall survival after the diagnosis of non-small-cell lung cancer Marliese Alexander, Rory Wolfe, David Ball, Matthew Conron, Robert G Stirling, Benjamin Solomon, Michael MacManus, Ann Officer, Sameer Karnam, Kate Burbury and Sue M Evans Br J Cancer 2017 117: 744-751; advance online publication, July 20, 2017; 10.1038/bjc.2017.232 Abstract | Full Text | | | | Leukocyte telomere length and renal cell carcinoma survival in two studies Catherine L Callahan, Kendra Schwartz, Julie J Ruterbusch, Brian Shuch, Barry I Graubard, Qing Lan, Richard Cawthon, Andrea A Baccarelli, Wong-Ho Chow, Nathaniel Rothman, Jonathan N Hofmann and Mark P Purdue Br J Cancer 2017 117: 752-755; advance online publication, July 25, 2017; 10.1038/bjc.2017.237 Abstract | Full Text | | Corrigenda | Top | | Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer A Kenneth MacLeod, Lourdes Acosta-Jimenez, Philip J Coates, Michael McMahon, Frank A Carey, Tadashi Honda, John D Hayes, Colin J Henderson and C Roland Wolf Br J Cancer 2017 117: e1; advance online publication, March 21, 2017; 10.1038/bjc.2017.80 Full Text | | | | The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer C B Lajer, E Garnæs, L Friis-Hansen, B Norrild, M H Therkildsen, M Glud, M Rossing, H Lajer, D Svane, L Skotte, L Specht, C Buchwald and F C Nielsen Br J Cancer 2017 117: e2; advance online publication, July 13, 2017; 10.1038/bjc.2017.203 Full Text | | | | Inhibition of OATP1B1 by tyrosine kinase inhibitors: in vitro-in vivo correlations S Hu, R H J Mathijssen, P de Bruijn, S D Baker and A Sparreboom Br J Cancer 2017 117: e3; advance online publication, July 13, 2017; 10.1038/bjc.2017.217 Full Text | | | | | Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to British Journal of Cancer. 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