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September 2016 Volume 17 Number 9 | |||||||||||||||||||||||||||||||||||||||||||||||
In this issue
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REVIEWS | Top | ||||||||||||||||||||||||||||||||||||||||||||||
Epigenetic mechanisms in neurogenesis Bing Yao et al. p537 | doi:10.1038/nrn.2016.70 The proliferation and differentiation of neural stem cells in the embryonic and adult brain are influenced by various processes, including epigenetic regulation. Song and colleagues review the epigenetic regulation of neurogenesis in health and in various brain disorders, placing their focus on DNA and histone modifications. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
Adhesion G protein-coupled receptors in nervous system development and disease Tobias Langenhan, Xianhua Piao & Kelly R. Monk p550 | doi:10.1038/nrn.2016.86 Adhesion G protein-coupled receptors (aGPCRs) have diverse functional roles in the nervous system. In this Review, the authors discuss the roles of these proteins in neural development, including cortical patterning, dendrite and synapse formation, and myelination. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
The enigmatic mossy cell of the dentate gyrus Helen E. Scharfman p562 | doi:10.1038/nrn.2016.87 Mossy cells are a major subpopulation of glutamatergic principal neurons within the dentate gyrus; however, their roles in hippocampal circuitry are poorly understood. Scharfman describes how new techniques to probe mossy cell function are shedding light on their contribution to hippocampal function and behaviour. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
Molecular mechanisms underlying alcohol-drinking behaviours Dorit Ron & Segev Barak p576 | doi:10.1038/nrn.2016.85 The development of alcohol use disorder involves a transition from the moderate use to the excessive, uncontrolled consumption of alcohol. Focusing on findings in rodents, Ron and Barak review the intracellular signalling cascades that underlie this transition and the molecular mechanisms that act against it. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
PERSPECTIVES | Top | ||||||||||||||||||||||||||||||||||||||||||||||
OPINION Time to connect: bringing social context into addiction neuroscience Markus Heilig, David H. Epstein, Michael A. Nader & Yavin Shaham p592 | doi:10.1038/nrn.2016.67 Research on the neural substrates of drug addiction has yet to be translated into a treatment of addiction. Heilig et al. propose that finding neural links between social factors, such as exclusion, and drug addiction would help to make addiction neuroscience research more clinically relevant. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
CORRESPONDENCE | Top | ||||||||||||||||||||||||||||||||||||||||||||||
Correspondence: Meanings of self-grooming depend on an inverted U-shaped function with aversiveness Alberto Fernández-Teruel & Celio Estanislau p591 | doi:10.1038/nrn.2016.102 Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
REPLY | Top | ||||||||||||||||||||||||||||||||||||||||||||||
Reply: 'Stressing' rodent self-grooming for neuroscience research Cai Song, Kent C. Berridge & Allan V. Kalueff p591 | doi:10.1038/nrn.2016.103 Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
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*2014 Journal Citation Report (Thomson Reuters, 2015) |
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