Leukemia - Table of Contents alert Volume 30 Issue 5

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Advertisement Blood Cancer Journal is an online-only, open access journal publishing high quality research on hematologic malignancies and related disorders. The journal has an Impact Factor of 3.467. Explore the benefits of submitting your next research article. TABLE OF CONTENTS Volume 30, Issue 5 (May 2016) In this issue Reviews Original Articles Letters to the Editor Also new AOP Sign up for e-alerts Recommend to your library Web feed Follow on Twitter Subscribe Advertisement BJC collections: Cancer Immunotherapy Immunotherapies have revolutionised therapy for some cancers. In parallel with therapeutic trials, many other mechanisms and pathways are being investigated in optimising these treatments.  Access this collection from British Journal of Cancer - free online for six months Produced with support from: EMD Serono   Reviews Top Management of relapsed multiple myeloma: recommendations of the International Myeloma Working Group J Laubach, L Garderet, A Mahindra, G Gahrton, J Caers, O Sezer, P Voorhees, X Leleu, H E Johnsen, M Streetly, A Jurczyszyn, H Ludwig, U-H Mellqvist, W-J Chng, L Pilarski, H Einsele, J Hou, I Turesson, E Zamagni, C S Chim, A Mazumder, J Westin, J Lu, T Reiman, S Kristinsson, D Joshua, M Roussel, P O'Gorman, E Terpos, P McCarthy, M Dimopoulos, P Moreau, R Z Orlowski, J S Miguel, K C Anderson, A Palumbo, S Kumar, V Rajkumar, B Durie and P G Richardson Leukemia 2016 30: 1005-1017; advance online publication, December 29, 2015; 10.1038/leu.2015.356 Abstract | Full Text Myeloproliferative neoplasms and inflammation: whether to target the malignant clone or the inflammatory process or both S Koschmieder, T I Mughal, H C Hasselbalch, G Barosi, P Valent, J-J Kiladjian, G Jeryczynski, H Gisslinger, J S Jutzi, H L Pahl, R Hehlmann, A Maria Vannucchi, F Cervantes, R T Silver and T Barbui Leukemia 2016 30: 1018-1024; advance online publication, February 8, 2016; 10.1038/leu.2016.12 Abstract | Full Text Original Articles Top ACUTE MYELOID LEUKEMIA The combination of FLT3 and DNA methyltransferase inhibition is synergistically cytotoxic to FLT3/ITD acute myeloid leukemia cells E Chang, S Ganguly, T Rajkhowa, C D Gocke, M Levis and H Konig Leukemia 2016 30: 1025-1032; advance online publication, December 21, 2015; 10.1038/leu.2015.346 Abstract | Full Text ACUTE LYMPHOBLASTIC LEUKEMIA CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1-induced T-cell acute lymphoblastic leukemia N Jena, J Sheng, J K Hu, W Li, W Zhou, G Lee, N Tsichlis, A Pathak, N Brown, A Deshpande, C Luo, G F Hu, P W Hinds, R A Van Etten and M G Hu Leukemia 2016 30: 1033-1043; advance online publication, December 28, 2015; 10.1038/leu.2015.353 Abstract | Full Text CHRONIC MYELOGENOUS LEUKEMIA Long-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial OPEN A Hochhaus, G Saglio, T P Hughes, R A Larson, D-W Kim, S Issaragrisil, P D le Coutre, G Etienne, P E Dorlhiac-Llacer, R E Clark, I W Flinn, H Nakamae, B Donohue, W Deng, D Dalal, H D Menssen and H M Kantarjian Leukemia 2016 30: 1044-1054; advance online publication, February 3, 2016; 10.1038/leu.2016.5 Abstract | Full Text CHRONIC LYMPHOCYTIC LEUKEMIA Next-generation IgVH sequencing CLL-like monoclonal B-cell lymphocytosis reveals frequent oligoclonality and ongoing hypermutation M Klinger, J Zheng, K S J Elenitoba-Johnson, S L Perkins, M Faham and D W Bahler Leukemia 2016 30: 1055-1061; advance online publication, December 21, 2015; 10.1038/leu.2015.351 Abstract | Full Text LYMPHOMA Recurrent activating mutations of CD28 in peripheral T-cell lymphomas J Rohr, S Guo, J Huo, A Bouska, C Lachel, Y Li, P D Simone, W Zhang, Q Gong, C Wang, A Cannon, T Heavican, A Mottok, S Hung, A Rosenwald, R Gascoyne, K Fu, T C Greiner, D D Weisenburger, J M Vose, L M Staudt, W Xiao, G E O Borgstahl, S Davis, C Steidl, T McKeithan, J Iqbal and W C Chan Leukemia 2016 30: 1062-1070; advance online publication, December 31, 2015; 10.1038/leu.2015.357 Abstract | Full Text MULTIPLE MYELOMA, GAMMOPATHIES Gene signature combinations improve prognostic stratification of multiple myeloma patients W J Chng, T-H Chung, S Kumar, S Usmani, N Munshi, H Avet-Loiseau, H Goldschmidt, B Durie and P Sonneveld on behalf of the International Myeloma Working Group Leukemia 2016 30: 1071-1078; advance online publication, December 16, 2015; 10.1038/leu.2015.341 Abstract | Full Text Risk factors for and outcomes of patients with POEMS syndrome who experience progression after first-line treatment T V Kourelis, F K Buadi, M A Gertz, M Q Lacy, S K Kumar, P Kapoor, R S Go, J A Lust, S R Hayman, V Rajkumar, S R Zeldenrust, S J Russell, D Dingli, Y Lin, N Leung, Y L Hwa, W Gonsalves, R A Kyle and A Dispenzieri Leukemia 2016 30: 1079-1085; advance online publication, December 16, 2015; 10.1038/leu.2015.344 Abstract | Full Text Dexamethasone treatment promotes Bcl-2 dependence in multiple myeloma resulting in sensitivity to venetoclax S M Matulis, V A Gupta, A K Nooka, H V Hollen, J L Kaufman, S Lonial and L H Boise Leukemia 2016 30: 1086-1093; advance online publication, December 28, 2015; 10.1038/leu.2015.350 Abstract | Full Text Single-cell analysis of targeted transcriptome predicts drug sensitivity of single cells within human myeloma tumors A K Mitra, U K Mukherjee, T Harding, J S Jang, H Stessman, Y Li, A Abyzov, J Jen, S Kumar, V Rajkumar and B Van Ness Leukemia 2016 30: 1094-1102; advance online publication, December 29, 2015; 10.1038/leu.2015.361 Abstract | Full Text Targeting vasculogenesis to prevent progression in multiple myeloma M Moschetta, Y Mishima, Y Kawano, S Manier, B Paiva, L Palomera, Y Aljawai, A Calcinotto, C Unitt, I Sahin, A Sacco, S Glavey, J Shi, M R Reagan, F Prosper, M Bellone, M Chesi, L P Bergsagel, A Vacca, A M Roccaro and I M Ghobrial Leukemia 2016 30: 1103-1115; advance online publication, February 3, 2016; 10.1038/leu.2016.3 Abstract | Full Text Clonal B cells in Waldenström’s macroglobulinemia exhibit functional features of chronic active B-cell receptor signaling OPEN K V Argyropoulos, R Vogel, C Ziegler, G Altan-Bonnet, E Velardi, M Calafiore, A Dogan, M Arcila, M Patel, K Knapp, C Mallek, Z R Hunter, S P Treon, M R M van den Brink and M L Palomba Leukemia 2016 30: 1116-1125; advance online publication, February 12, 2016; 10.1038/leu.2016.8 Abstract | Full Text CHRONIC MYLEPROLIFERATIVE NEOPLASMS Clinical impact of bone marrow morphology for the diagnosis of essential thrombocythemia: comparison between the BCSH and the WHO criteria OPEN H Gisslinger, G Jeryczynski, B Gisslinger, A Wölfler, S Burgstaller, V Buxhofer-Ausch, M Schalling, M-T Krauth, A-I Schiefer, C Kornauth, I Simonitsch-Klupp, C Beham-Schmid, L Müllauer and J Thiele Leukemia 2016 30: 1126-1132; advance online publication, December 29, 2015; 10.1038/leu.2015.360 Abstract | Full Text STEM CELL BIOLOGY Dnmt3a regulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells O A Guryanova, Y K Lieu, F E Garrett-Bakelman, B Spitzer, J L Glass, K Shank, A B V Martinez, S A Rivera, B H Durham, F Rapaport, M D Keller, S Pandey, L Bastian, D Tovbin, A R Weinstein, J Teruya-Feldstein, O Abdel-Wahab, V Santini, C E Mason, A M Melnick, S Mukherjee and R L Levine Leukemia 2016 30: 1133-1142; advance online publication, December 29, 2015; 10.1038/leu.2015.358 Abstract | Full Text STEM CELL TRANSPLANTATION Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1 OPEN L Zanotti, R Angioni, B Calì, C Soldani, C Ploia, F Moalli, M Gargesha, G D'Amico, S Elliman, G Tedeschi, E Maffioli, A Negri, S Zacchigna, A Sarukhan, J V Stein and A Viola Leukemia 2016 30: 1143-1154; advance online publication, February 22, 2016; 10.1038/leu.2016.33 Abstract | Full Text TRANSCRIPTIONAL CONTROL AND SIGNAL TRANSDUCTION, CELL CYCLE BCOR regulates myeloid cell proliferation and differentiation Q Cao, M D Gearhart, S Gery, S Shojaee, H Yang, H Sun, D-c Lin, J-w Bai, M Mead, Z Zhao, Q Chen, W-w Chien, S Alkan, T Alpermann, T Haferlach, M Müschen, V J Bardwell and H P Koeffler Leukemia 2016 30: 1155-1165; advance online publication, February 5, 2016; 10.1038/leu.2016.2 Abstract | Full Text ANIMAL MODELS The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models S Dutta, A Krause, S Vosberg, T Herold, B Ksienzyk, L Quintanilla-Martinez, B Tizazu, M Chopra, A Graf, S Krebs, H Blum, P A Greif, A Vetter, K Metzeler, M Rothenberg-Thurley, M R Schneider, M Dahlhoff, K Spiekermann, U Zimber-Strobl, E Wolf and S K Bohlander Leukemia 2016 30: 1166-1176; advance online publication, December 21, 2015; 10.1038/leu.2015.349 Abstract | Full Text Letters to the Editor Top Effect of the type of treatment facility on the outcome of acute myeloid leukemia in adolescents and young adults R S Go, A C Bartley, A Al-Kali, N D Shah and E B Habermann Leukemia 2016 30: 1177-1180; advance online publication, August 26, 2015; 10.1038/leu.2015.239 Full Text Unrelated cord blood transplantation for childhood acute myelogenous leukemia: The influence of cytogenetic risk group stratification G Michel, R Cunha, A Ruggeri, T A O'Brien, H Bittencourt, J H Dalle, F Locatelli, A P Iori, M Mauad, C Oudin, F Giannotti, F Volt, E Gluckman, P Bader and V Rocha on behalf of Eurocord, Cord Blood Committee of Cellular Therapy Immunobiology and Pediatric Disease Working parties of EBMT Leukemia 2016 30: 1180-1183; advance online publication, September 15, 2015; 10.1038/leu.2015.243 Full Text Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant-99 protocol E M C Driessen, P de Lorenzo, M Campbell, M Felice, A Ferster, I Hann, A Vora, L Hovi, G Escherich, C K Li, G Mann, T Leblanc, F Locatelli, A Biondi, J Rubnitz, M Schrappe, L Silverman, J Stary, R Suppiah, T Szczepanski, M Valsecchi and R Pieters Leukemia 2016 30: 1184-1187; advance online publication, September 15, 2015; 10.1038/leu.2015.246 Full Text Risk factors for second acute myeloid leukemia/myelodysplastic syndrome among survivors of non-Hodgkin lymphoma C J K Lam, R E Curtis, G M Dores, E A Engels, N E Caporaso, A Polliack, J L Warren, H A Young, P H Levine, A F Elmi, J F Fraumeni, M A Tucker and L M Morton Leukemia 2016 30: 1187-1190; advance online publication, September 15, 2015; 10.1038/leu.2015.248 Full Text Comprehensive quantitative proteomic profiling of the pharmacodynamic changes induced by MLN4924 in acute myeloid leukemia cells establishes rationale for its combination with azacitidine V Visconte, S T Nawrocki, C M Espitia, K R Kelly, A Possemato, S A Beausoleil, Y Han, H E Carraway, A Nazha, A S Advani, J P Maciejewski, M A Sekeres and J S Carew Leukemia 2016 30: 1190-1194; advance online publication, September 15, 2015; 10.1038/leu.2015.250 Full Text A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros J L Wiemels, A J de Smith, J Xiao, S-T Lee, M O Muench, M E Fomin, M Zhou, H M Hansen, A Termuhlen, C Metayer and K M Walsh Leukemia 2016 30: 1194-1197; advance online publication, September 16, 2015; 10.1038/leu.2015.251 Full Text Identification of characteristic and prognostic values of chromosome 1p abnormality by multi-gene fluorescence in situ hybridization in multiple myeloma F Li, L Hu, Y Xu, Z Li, S Yi, Z Gu, C Li, M Hao, K Ru, F Zhan, A Zetterberg, W Yuan, T Cheng and L Qiu Leukemia 2016 30: 1197-1201; advance online publication, September 16, 2015; 10.1038/leu.2015.254 Full Text Hematopoietic stem cell transplantation for T-cell large granular lymphocyte leukemia: a retrospective study of the European Society for Blood and Marrow Transplantation T Marchand, T Lamy, H Finel, W Arcese, S Choquet, J Finke, A Huynh, G Irrera, D Karakasis, J Konopacki, J Lambert, M Michieli, H C Schouten, W Schroyens, G Sucak, J Tischer, E Vandenberghe and P Dreger on behalf of the Lymphoma Working Party of the EBMT Leukemia 2016 30: 1201-1204; advance online publication, September 22, 2015; 10.1038/leu.2015.256 Full Text Activating somatic mutations outside the SH2-domain of STAT3 in LGL leukemia E Andersson, H Kuusanmäki, S Bortoluzzi, S Lagström, A Parsons, H Rajala, A van Adrichem, S Eldfors, T Olson, M J Clemente, A Laasonen, P Ellonen, C Heckman, T P Loughran, J P Maciejewski and S Mustjoki Leukemia 2016 30: 1204-1208; advance online publication, September 30, 2015; 10.1038/leu.2015.263 Full Text Paroxysmal nocturnal hemoglobinuria induced by the occurrence of BCR-ABL in a PIGA mutant hematopoietic progenitor cell R Tominaga, T Katagiri, K Kataoka, K Kataoka, R K C Wee, A Maeda, H Gomyo, I Mizuno, T Murayama, S Ogawa and S Nakao Leukemia 2016 30: 1208-1210; advance online publication, October 6, 2015; 10.1038/leu.2015.268 Full Text Prospective molecular monitoring of minimal residual disease after non-myeloablative allografting in newly diagnosed multiple myeloma M Ladetto, S Ferrero, D Drandi, M Festuccia, F Patriarca, N Mordini, S Cena, R Benedetto, G Guarona, F Ferrando, L Brunello, P Ghione, V Boccasavia, R Fanin, P Omedè, L Giaccone, A Palumbo, R Passera, M Boccadoro and B Bruno Leukemia 2016 30: 1211-1214; advance online publication, October 6, 2015; 10.1038/leu.2015.269 Full Text Oncogenic activation of MPL/thrombopoietin receptor by 17 mutations at W515: implications for myeloproliferative neoplasms J-P Defour, I Chachoua, C Pecquet and S N Constantinescu Leukemia 2016 30: 1214-1216; advance online publication, October 6, 2015; 10.1038/leu.2015.271 Full Text Idiotype-specific CD4+ T cells eradicate disseminated myeloma O A Haabeth, A Tveita, M Fauskanger, K Hennig, P O Hofgaard and B Bogen Leukemia 2016 30: 1216-1220; advance online publication, October 9, 2015; 10.1038/leu.2015.278 Full Text Impact of FLT3-ITD location on sensitivity to TKI-therapy in vitro and in vivo P Arreba-Tutusaus, T S Mack, L Bullinger, T M Schnöder, A Polanetzki, S Weinert, A Ballaschk, Z Wang, A J Deshpande, S A Armstrong, K Döhner, T Fischer and F H Heidel Leukemia 2016 30: 1220-1225; advance online publication, October 21, 2015; 10.1038/leu.2015.292 Full Text Palmitoylacyltransferase Zdhhc9 inactivation mitigates leukemogenic potential of oncogenic Nras P Liu, B Jiao, R Zhang, H Zhao, C Zhang, M Wu, D Li, X Zhao, Q Qiu, J Li and R Ren Leukemia 2016 30: 1225-1228; advance online publication, October 22, 2015; 10.1038/leu.2015.293 Full Text Advertisement The International Chronic Myeloid Leukemia Foundation (iCMLf) are pleased to share with you, the Handbook of Chronic Myeloid Leukemia Timothy P. Hughes, et al (2016). Download your free copy today The iCMLf have partnered with Springer Healthcare IME to bring this book to hematologists with a strong interest in Chronic Myeloid Leukemia. This practical handbook provides healthcare providers involved in the diagnosis and treatment of CML with a concise and up-to-date survey of the field. This independent educational resource is supported by a grant from Novartis Oncology. Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com More Nature Events Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to Leukemia. 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