International Journal of Obesity - Table of Contents alert Volume 40 Issue 2

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Special Issue: All roads lead to the brain Guest Editor: Margriet Westerterp-Plantenga In recent years it became increasingly clear that the underlying disturbances in the regulation of energy homeostasis, despite their differences, share certain key features. Metabolic perturbations are key pathogenic mechanisms involved in obesity and responsible for the phenotypic expression of different acute and chronic diseases. Neurons throughout the CNS, but highly concentrated in some specific brain areas, sense humoral and neural signals of systemic energy status and relay this information to secondary neurons that regulate physiological processes so as to maintain energy homeostasis. The pertinent neuronal circuits must integrate information about short-term changes in nutrient availability in the context of long-term energy status. This requires mechanisms that rapidly and reversibly adjust the responsiveness of the involved neuronal circuits to changes in nutrient availability. This special issue addresses some examples, such as sexual dimorphism in the development of metabolic complications; intestinal GLP-1 and satiation, from man to rodents and back; new insights on the role of the endocannabinoid system in the regulation of energy balance; and finally anorexia/cachexia and obesity as two sides of the same coin. In summary, the papers in this special section of the International Journal of Obesity present a multifaceted approach to a fascinating, rapidly developing and important area of research. TABLE OF CONTENTS Volume 40, Issue 2 (February 2016) In this issue Special Editorial Special Reviews Reviews Original Articles Corrigendum Also new AOP Sign up for e-alerts Recommend to your library Web feed Follow on Twitter Subscribe Special Editorial Top Introduction to ‘All roads take to the brain: neural control of energy homeostasis in health and disease’ W Langhans, H-R Berthoud and M Westerterp-Plantenga Int J Obes 2016 40: 191-192; 10.1038/ijo.2015.245 Full Text | PDF Special Reviews Top Anorexia–cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15 V W W Tsai, S Lin, D A Brown, A Salis and S N Breit Int J Obes 2016 40: 193-197; advance online publication, December 1, 2015; 10.1038/ijo.2015.242 Abstract | Full Text Intestinal GLP-1 and satiation: from man to rodents and back R E Steinert, C Beglinger and W Langhans Int J Obes 2016 40: 198-205; advance online publication, August 28, 2015; 10.1038/ijo.2015.172 Abstract | Full Text A sexually dimorphic hypothalamic response to chronic high-fat diet consumption E Morselli, A P Frank, B F Palmer, C Rodriguez-Navas, A Criollo and D J Clegg Int J Obes 2016 40: 206-209; advance online publication, June 15, 2015; 10.1038/ijo.2015.114 Abstract | Full Text New insights on the role of the endocannabinoid system in the regulation of energy balance B Gatta-Cherifi and D Cota Int J Obes 2016 40: 210-219; advance online publication, September 16, 2015; 10.1038/ijo.2015.179 Abstract | Full Text Reviews Top Association of overweight and obesity with patient mortality after acute myocardial infarction: a meta-analysis of prospective studies L Wang, W Liu, X He, Y Chen, J Lu, K Liu, K Cao and P Yin Int J Obes 2016 40: 220-228; advance online publication, September 4, 2015; 10.1038/ijo.2015.176 Abstract | Full Text The early origins of obesity and insulin resistance: timing, programming and mechanisms L M Nicholas, J L Morrison, L Rattanatray, S Zhang, S E Ozanne and I C McMillen Int J Obes 2016 40: 229-238; advance online publication, September 14, 2015; 10.1038/ijo.2015.178 Abstract | Full Text Original Articles Top PEDIATRICS What accounts for ethnic differences in newborn skinfold thickness comparing South Asians and White Caucasians? Findings from the START and FAMILY Birth Cohorts OPEN S S Anand, M K Gupta, K M Schulze, D Desai, N Abdalla, G Wahi, C Wade, P Scheufler, S D McDonald, K M Morrison, A Vasudevan, P Dwarakanath, K Srinivasan, A Kurpad, H C Gerstein and K K Teo on behalf of the START and FAMILY investigators Int J Obes 2016 40: 239-244; advance online publication, August 28, 2015; 10.1038/ijo.2015.171 Abstract | Full Text The bigger, the stronger? Insights from muscle architecture and nervous characteristics in obese adolescent girls S Garcia-Vicencio, E Coudeyre, V Kluka, C Cardenoux, A-G Jegu, A-V Fourot, S Ratel and V Martin Int J Obes 2016 40: 245-251; advance online publication, August 19, 2015; 10.1038/ijo.2015.158 Abstract | Full Text INTEGRATIVE BIOLOGY Inverse relationship between a genetic risk score of 31 BMI loci and weight change before and after reaching middle age OPEN G Rukh, S Ahmad, U Ericson, G Hindy, T Stocks, F Renström, P Almgren, P M Nilsson, O Melander, P W Franks and M Orho-Melander Int J Obes 2016 40: 252-259; advance online publication, September 16, 2015; 10.1038/ijo.2015.180 Abstract | Full Text Association of metabolic parameters and rs726344 in FNDC5 with serum irisin concentrations T Ebert, S Kralisch, U Wurst, M Scholz, M Stumvoll, P Kovacs, M Fasshauer and A Tönjes Int J Obes 2016 40: 260-265; advance online publication, August 19, 2015; 10.1038/ijo.2015.157 Abstract | Full Text CLINICAL STUDIES AND PRACTICE Differential effects of leptin on adiponectin expression with weight gain versus obesity P Singh, P Sharma, K R Sahakyan, D E Davison, F H Sert-Kuniyoshi, A Romero-Corral, J M Swain, M D Jensen, F Lopez-Jimenez, T Kara and V K Somers Int J Obes 2016 40: 266-274; advance online publication, September 16, 2015; 10.1038/ijo.2015.181 Abstract | Full Text Changes in inflammation, oxidative stress and adipokines following bariatric surgery among adolescents with severe obesity A S Kelly, J R Ryder, K L Marlatt, K D Rudser, T Jenkins and T H Inge Int J Obes 2016 40: 275-280; advance online publication, August 28, 2015; 10.1038/ijo.2015.174 Abstract | Full Text Effects of RYGB on energy expenditure, appetite and glycaemic control: a randomized controlled clinical trial J B Schmidt, S D Pedersen, N T Gregersen, L Vestergaard, M S Nielsen, C Ritz, S Madsbad, D Worm, D L Hansen, T R Clausen, J F Rehfeld, A Astrup, J J Holst and A Sjödin Int J Obes 2016 40: 281-290; advance online publication, August 25, 2013; 10.1038/ijo.2015.162 Abstract | Full Text LAP-BAND for BMI 30–40: 5-year health outcomes from the multicenter pivotal study J B Dixon, L L Eaton, V Vincent and R Michaelson for the LAP-BAND Lower BMI Study Group Int J Obes 2016 40: 291-298; advance online publication, August 18, 2015; 10.1038/ijo.2015.156 Abstract | Full Text Protein intake and lean body mass preservation during energy intake restriction in overweight older adults E M P Backx, M Tieland, K J Borgonjen-van den Berg, P R Claessen, L J C van Loon and L C P G M de Groot Int J Obes 2016 40: 299-304; advance online publication, October 16, 2015; 10.1038/ijo.2015.182 Abstract | Full Text Effect of extended morning fasting upon ad libitum lunch intake and associated metabolic and hormonal responses in obese adults OPEN E A Chowdhury, J D Richardson, K Tsintzas, D Thompson and J A Betts Int J Obes 2016 40: 305-311; advance online publication, August 17, 2015; 10.1038/ijo.2015.154 Abstract | Full Text Modelling the associations between fat-free mass, resting metabolic rate and energy intake in the context of total energy balance M Hopkins, G Finlayson, C Duarte, S Whybrow, P Ritz, G W Horgan, J E Blundell and R J Stubbs Int J Obes 2016 40: 312-318; advance online publication, August 17, 2015; 10.1038/ijo.2015.155 Abstract | Full Text ADIPOCYTE AND CELL BIOLOGY Anti-inflammatory properties of bone morphogenetic protein 4 in human adipocytes E Baraban, T Chavakis, B S Hamilton, S Sales, M Wabitsch, S R Bornstein and M Ehrhart-Bornstein Int J Obes 2016 40: 319-327; advance online publication, July 31, 2015; 10.1038/ijo.2015.141 Abstract | Full Text BEHAVIOR AND PSYCHOLOGY Helpful or harmful? Prospective association between weight misperception and weight gain among overweight and obese adolescents and young adults K R Sonneville, I B Thurston, C E Milliren, R C Kamody, H C Gooding and T K Richmond Int J Obes 2016 40: 328-332; advance online publication, August 25, 2015; 10.1038/ijo.2015.166 Abstract | Full Text Weight-based discrimination: an ubiquitary phenomenon? C Sikorski, J Spahlholz, M Hartlev and S G Riedel-Heller Int J Obes 2016 40: 333-337; advance online publication, August 27, 2015; 10.1038/ijo.2015.165 Abstract | Full Text ANIMAL MODELS Integrative systems analysis of diet-induced obesity identified a critical transition in the transcriptomes of the murine liver and epididymal white adipose tissue J Kim, E-Y Kwon, S Park, J-R Kim, S-w Choi, M-S Choi and S-J Kim Int J Obes 2016 40: 338-345; advance online publication, August 13, 2015; 10.1038/ijo.2015.147 Abstract | Full Text Genetic control of obesity, glucose homeostasis, dyslipidemia and fatty liver in a mouse model of diet-induced metabolic syndrome D S Sinasac, J D Riordan, S H Spiezio, B S Yandell, C M Croniger and J H Nadeau Int J Obes 2016 40: 346-355; advance online publication, September 18, 2015; 10.1038/ijo.2015.184 Abstract | Full Text Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK Y-h Lee, M R Yun, H M Kim, B H Jeon, B-C Park, B-W Lee, E S Kang, H C Lee, Y W Park and B-S Cha Int J Obes 2016 40: 356-365; advance online publication, August 28, 2015; 10.1038/ijo.2015.173 Abstract | Full Text Pro-inflammatory obesity in aged cannabinoid-2 receptor-deficient mice K Schmitz, N Mangels, A Häussler, N Ferreirós, I Fleming and I Tegeder Int J Obes 2016 40: 366-379; advance online publication, August 25, 2015; 10.1038/ijo.2015.169 Abstract | Full Text Corrigendum Top Childhood obesity: evidence for distinct early and late environmental determinants a 12-year longitudinal cohort study (EarlyBird 62) M Mostazir, A Jeffery, L Voss and T Wilkin Int J Obes 2016 40: 380; 10.1038/ijo.2015.248 Full Text Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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