 | | Neurodegeneration: Possible evidence for human transmission of Alzheimer’s pathology |  | Credit: Jaunmuktane et al./Nature | | Amyloid beta pathology in the grey matter and blood vessel walls characteristic of Alzheimer’s disease (AD) and the related cerebral amyloid angiopathy (CAA) is observed in the brains of deceased patients who acquired Creutzfeldt–Jakob disease (CJD) following treatment with prion-contaminated human growth hormone. Although there is no evidence that human prion disease, AD or CAA is contagious, the study of eight patients, published in this week’s Nature, suggests that amyloid beta (the peptides that form the main components of the amyloid plaques found in the brains of patients with AD) may potentially be transmissible via certain medical procedures. Access the news story and paper online, and read the related News & Views article. | | |  | As a registered user of Nature Publishing Group's Web sites, our database indicates that you have opted-in to receive product information and special offers. If you no longer wish to receive these e-mails or to discontinue all e-mail services from Nature Publishing Group please update your online account. Modify My Account (Log in to be recognised as a Nature.com registrant). For further information on technical assistance | print subscriptions | other enquiries. Nature Publishing Group | Principal offices: London | New York and Tokyo, and offices in cities worldwide including Basingstoke | Barcelona | Boston | Buenos Aires | Cairo | Delhi | Heidelberg | Madrid | Melbourne | Mexico City | Mumbai | Munich | Paris | San Francisco | Sao Paulo | Seoul | Shanghai and Washington DC. Macmillan Publishers Limited is a company incorporated in England & Wales under company number 785998 & whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. Nature Publishing Group | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | US © 2015 Nature Publishing Group, a division of Macmillan Publishers Limited. All rights reserved. | |
No comments:
Post a Comment