The EMBO Journal Table of Contents for 4 August 2015; Vol. 34, No. 15

4 August 2015 | Volume 34, Number 15 Submit Table of Contents Have you seen? Articles Volume 34, Number 15 Have you seen? Does Arabidopsis thaliana DREAM of cell cycle control? A new study indicates the presence of DREAM complexes in the plant Arabidopsis, highlighting a conserved role of DREAM complexes in cell cycle‐dependent gene expression. Martin Fischer and James A DeCaprio Published online 18.06.2015 Myc or no Myc, that is the question Recent work illustrates how c‐MYC is selectively induced and amplified in antigen‐specific T cells that undergo massive clonal expansion for host protection against pathogen infection. Chun Chou and Takeshi Egawa Published online 02.07.2015 Articles Transcriptional repression by MYB3R proteins regulates plant organ growth Activator and DREAM‐like repressor R1R2R3‐Myb transcription factors act coordinately to regulate mitotic target genes and organ growth in Arabidopsis thaliana. Kosuke Kobayashi, Toshiya Suzuki, Eriko Iwata, Norihito Nakamichi, Takamasa Suzuki, Poyu Chen, Misato Ohtani, Takashi Ishida, Hanako Hosoya, Sabine Müller, Tünde Leviczky, Aladár Pettkó‐Szandtner, Zsuzsanna Darula, Akitoshi Iwamoto, Mika Nomoto, Yasuomi Tada, Tetsuya Higashiyama, Taku Demura, John H Doonan, Marie‐Theres Hauser, Keiko Sugimoto, Masaaki Umeda, Zoltán Magyar, László Bögre, and Masaki Ito Published online 11.06.2015 Single cell tuning of Myc expression by antigen receptor signal strength and interleukin‐2 in T lymphocytes A combination of digital and analogue processes allows tight control of Myc expression at the population and single cell level during T lymphocyte immune responses and matches Myc expression to biosynthetic demands. Gavin C Preston, Linda V Sinclair, Aneesa Kaskar, Jens L Hukelmann, Maria N Navarro, Isabel Ferrero, H Robson MacDonald, Victoria H Cowling, and Doreen A Cantrell Published online 01.07.2015 Robust intestinal homeostasis relies on cellular plasticity in enteroblasts mediated by miR‐8–Escargot switch In normal physiological conditions, Drosophila intestinal stem cells generate a pool of undifferentiated enteroblasts with mesenchymal characteristics. Upon injury, miR‐8 is expressed locally inducing their epithelial differentiation through the repression of mesenchymal determinants. Zeus A Antonello, Tobias Reiff, Esther Ballesta‐Illan, and Maria Dominguez Published online 15.06.2015 Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion Transcriptome profiling of murine CD8 T cells from tumor tissue shows that the transcriptional regulator Maf1 is overexpressed in exhausted CD8 T cells and contributes to the dampening of anti‐tumor T‐cell responses. Marilyn Giordano, Coralie Henin, Julien Maurizio, Claire Imbratta, Pierre Bourdely, Michel Buferne, Lukas Baitsch, Laurent Vanhille, Michael H Sieweke, Daniel E Speiser, Nathalie Auphan‐Anezin, Anne‐Marie Schmitt‐Verhulst, and Grégory Verdeil Published online 02.07.2015 Regulation of synaptic activity by snapin‐mediated endolysosomal transport and sorting Snapin‐mediated endolysosomal trafficking and sorting maintain synaptic vesicle pool size and fine‐tune the Ca2+ sensitivity of evoked exocytosis. Jerome Di Giovanni and Zu‐Hang Sheng Published online 24.06.2015 TRIM5α requires Ube2W to anchor Lys63‐linked ubiquitin chains and restrict reverse transcription The anti‐retroviral factor TRIM5α restricts viral reverse transcription by recruiting two E2 Ub conjugation enzymes, leading to K63‐polyubiquitin chain anchoring to multiple internal TRIM5α lysine residues. Adam J Fletcher, Devin E Christensen, Chad Nelson, Choon Ping Tan, Torsten Schaller, Paul J Lehner, Wesley I Sundquist, and Greg J Towers Published online 22.06.2015 And‐1 coordinates with Claspin for efficient Chk1 activation in response to replication stress The recovery of stalled replication forks depends on And‐1 accumulation at DNA damage sites, which enhances Claspin–Chk1 interaction and DNA replication checkpoint Chk1 activation. Jing Hao, Christelle de Renty, Yongming Li, Haijie Xiao, Michael G Kemp, Zhiyong Han, Melvin L DePamphilis, and Wenge Zhu Published online 16.06.2015   Unsubscribe from or edit your subscription for this service. Or by mail: Customer Service * 425 Broadway St * Redwood City, CA 94063 * U.S.A. Copyright © 2015 by the European Molecular Biology Organisation.