Nature Reviews Neuroscience contents July 2015 Volume 16 Number 7 pp 373-439

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TABLE OF CONTENTS
July 2015 Volume 16 Number 7
Impact Factor 31.376 *	In this issue Research Highlights Reviews Perspectives Correspondence Also this month Article series: Stress Poster: Cell-reprogramming technology and neuroscience  Featured article: The neuroscience of placebo effects: connecting context, learning and health Tor D. Wager & Lauren Y. Atlas
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RESEARCH HIGHLIGHTS Top Synaptic plasticity: Micro-level disruption p373 | doi:10.1038/nrn3989 A study shows that elevated levels of the microRNA encoded by the schizophrenia-linked gene mir-137 impair presynaptic plasticity and hippocampus-dependent learning and memory in mice. PDF Axon guidance: Setting up for seeing in slow motion p374 | doi:10.1038/nrn3979 Interactions among semaphorin 6A, plexin A2 and plexin A4, and between contactin 4 and amyloid precursor protein, are crucial for the normal development of the circuits underlying vertical and horizontal optokinetic reflexes, respectively. PDF Axon regeneration: Splicing up repair mechanisms p374 | doi:10.1038/nrn3981 Components of the RNA repair and splicing machinery are shown to have a role in regulating axon regenerative capacity in fly sensory neurons. PDF Neural circuits: Pruning the projections p375 | doi:10.1038/nrn3980 Disruption of actin polymerization in the frontal cortex, which causes abnormal dendritic spine structures, results in locomotor hyperactivity owing to dysregulation of a midbrain dopaminergic circuit. PDF Neurodegenerative disease: Expanding neurodegeneration modelling p376 | doi:10.1038/nrn3982 Research into the underlying pathology of c9FTD/ALS has been hampered by a lack of good mouse models, but a new study reports a mouse model that recapitulates both the cellular and the behavioural pathology associated with these disorders. PDF IN BRIEF Depression: A receptor for resilience | Pain: Essential gene for nociceptors | GLIA: Feeling the pressure | Neurophysiology: Coding motor plans PDF Neuroscience JOBS of the week Tenure Track Faculty Position University of California Los Angeles Postdoctoral Research Associate Benaroya Research Institute at Virginia Mason (BRI) Research Associate Loyola University Chicago ELSC Postdoctoral Program The Edmond and Lily Safra Center for Brain Sciences at the Hebrew University of Jerusalem Neurobiologist Rutgers University More Science jobs from Neuroscience EVENT 23rd Annual International STRESS AND BEHAVIOR Neuroscience and Biopsychiatry Conference 19.05.16 Russian Federation More science events from
REVIEWS		Top
Article series: Stress Stress-related synaptic plasticity in the hypothalamus Jaideep S. Bains, Jaclyn I. Wamsteeker Cusulin & Wataru Inoue p377 | doi:10.1038/nrn3881 Exposure to one stressor can lead to altered responses to subsequent stressors, implying that the neural circuits that mediate stress responses undergo adaptive changes. Bains and colleagues review mechanisms of synaptic plasticity in the paraventricular nucleus of the hypothalamus that may contribute to such responses. Abstract | Full Text | PDF
Crosstalk between the nociceptive and immune systems in host defence and disease Stephen B. McMahon, Federica La Russa & David L. H. Bennett p389 | doi:10.1038/nrn3946 Bidirectional signalling between nociceptors and immune cells protects the host from potential threats to homeostasis. In this Review, McMahon and colleagues discuss how, when such signalling becomes uncontrolled or dysfunctional, it can contribute to immune-mediated diseases and persistent pain states. Abstract | Full Text | PDF
The neuroscience of placebo effects: connecting context, learning and health Tor D. Wager & Lauren Y. Atlas p403 | doi:10.1038/nrn3976 Placebo effects are positive effects on health that arise from the response of the brain to the contextual information that accompanies the delivery of a treatment. In this Review, Wager and Atlas examine the neural mechanisms that underlie such effects, focusing on placebo analgesia. Abstract | Full Text | PDF | Supplementary information
PERSPECTIVES		Top
OPINION Interoceptive predictions in the brain Lisa Feldman Barrett & W. Kyle Simmons p419 | doi:10.1038/nrn3950 The brain is increasingly thought to predict sensory inputs, based on previous experience. In this Opinion article, Barrett and Simmons integrate this active inference account with an anatomical model of corticocortical connections, and describe how such a system may unify allostatic control and interoception within an integrated neural architecture. Abstract | Full Text | PDF | Supplementary information
OPINION Rethinking segregation and integration: contributions of whole-brain modelling Gustavo Deco, Giulio Tononi, Melanie Boly & Morten L. Kringelbach p430 | doi:10.1038/nrn3963 The brain balances the segregation and integration of incoming information to facilitate flexible cognition and behaviour. In this Opinion article, Deco and colleagues argue that whole-brain computational modelling based on neuroimaging data can provide insights into these segregation and integration processes. Abstract | Full Text | PDF
CORRESPONDENCE		Top
Neural mechanisms of mindfulness meditation: bridging clinical and neuroscience investigations Anne Maj van der Velden & Andreas Roepstorff p439 | doi:10.1038/nrn3916-c1 Full Text | PDF
Erratum: Neuronal circuits for fear and anxiety Philip Tovote, Jonathan Paul Fadok & Andreas Lüthi p439 | doi:10.1038/nrn3984 Full Text | PDF
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