The EDGE

Recessive Dystrophic Epidermolysis Bullosa: Advances in the Laboratory Leading to New Therapies

David T Woodley and Mei Chen

J Invest Dermatol 2015 135: 1705-1707; 10.1038/jid.2015.149

Clinical Snippets

J Invest Dermatol 2015 135: 1708; 10.1038/jid.2015.168

BJD Editor's Choice

J Invest Dermatol 2015 135: 1709; 10.1038/jid.2015.169

Editors' Picks

J Invest Dermatol 2015 135: 1710; 10.1038/jid.2015.170

Research Techniques Made Simple

Drug Survival Studies in Dermatology:Principles, Purposes, and Pitfalls

Juul M P A van den Reek, Wietske Kievit, Robert Gniadecki, Jelle J Goeman, Jeffrey Zweegers, Peter C M van de Kerkhof, Marieke M B Seyger and Elke M G J de Jong

J Invest Dermatol 2015 135: e34; 10.1038/jid.2015.171

JID VisualDx Quiz

JID VisualDx Quiz: July 2015

Xiaolong Zhou and Mariya Miteva

J Invest Dermatol 2015 135: e30; 10.1038/jid.2015.172

Cells to Surgery Quiz

Cells to Surgery Quiz: July 2015

Mohammed Alsaidan, Brian J Simmons, Fleta N Bray, Mohammad-Ali Yazdani Abyaneh and Keyvan Nouri

J Invest Dermatol 2015 135: e15; 10.1038/jid.2015.173

Commentaries

Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity

Matthew O Ivory, James C Birchall and Vincent Piguet

J Invest Dermatol 2015 135: 1711-1712; 10.1038/jid.2014.544

A New View of Vitiligo: Looking at Normal-Appearing Skin

Mauro Picardo and Emanuela Bastonini

J Invest Dermatol 2015 135: 1713-1714; 10.1038/jid.2015.92

EDA Fibronectin in Keloids Create a Vicious Cycle of Fibrotic Tumor Formation

Rhiannon M Kelsh, Paula J McKeown-Longo and Richard A F Clark

J Invest Dermatol 2015 135: 1714-1718; 10.1038/jid.2015.155

Feather on the Cap of Medicine

Cathleen Tsz Ka Chiu and Cheng Ming Chuong

J Invest Dermatol 2015 135: 1719-1721; 10.1038/jid.2015.2

Reviews

Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin

Marco Demaria, Pierre Yves Desprez, Judith Campisi and Michael C Velarde

J Invest Dermatol 2015 135: 1722-1726; advance online publication, April 9, 2015; 10.1038/jid.2015.108

Original Articles

CLINICAL RESEARCH

Acne Treatment Based on Selective Photothermolysis of Sebaceous Follicles with Topically Delivered Light-Absorbing Gold Microparticles^JIDOPEN

Dilip Y Paithankar, Fernanda H Sakamoto, William A Farinelli, Garuna Kositratna, Richard D Blomgren, Todd J Meyer, Linda J Faupel, Arielle N B Kauvar, Jenifer R Lloyd, Wang L Cheung, Witold D Owczarek, Anna M Suwalska, Katarzyna B Kochanska, Agnieszka K Nawrocka, Elwira B Paluchowska, Katarzyna M Podolec, Magdalena M Pirowska, Anna B Wojas-Pelc and R Rox Anderson

J Invest Dermatol 2015 135: 1727-1734; advance online publication, March 6, 2015; 10.1038/jid.2015.89

GENETICS

A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots

Leonie C Jacobs, Merel A Hamer, David A Gunn, Joris Deelen, Jaspal S Lall, Diana van Heemst, Hae-Won Uh, Albert Hofman, André G Uitterlinden, Christopher E M Griffiths, Marian Beekman, P Eline Slagboom, Manfred Kayser, Fan Liu and Tamar Nijsten

J Invest Dermatol 2015 135: 1735-1742; advance online publication, February 23, 2015; 10.1038/jid.2015.62

IMMUNOLOGY/INFECTION

Dermal CD14⁺ Dendritic Cell and Macrophage Infection by Dengue Virus Is Stimulated by Interleukin-4

Evelyne Schaeffer, Vincent Flacher, Vasiliki Papageorgiou, Marion Decossas, Jean-Daniel Fauny, Melanie Krämer and Christopher G Mueller

J Invest Dermatol 2015 135: 1743-1751; advance online publication, December 18, 2014; 10.1038/jid.2014.525

The Characterization of Varicella Zoster Virus–Specific T Cells in Skin and Blood during Aging

Milica Vukmanovic-Stejic, Daisy Sandhu, Judith A Seidel, Neil Patel, Toni O Sobande, Elaine Agius, Sarah E Jackson, Judilyn Fuentes-Duculan, Mayte Suárez-Fariñas, Neil A Mabbott, Katie E Lacy, Graham Ogg, Frank O Nestle, James G Krueger, Malcolm H A Rustin and Arne N Akbar

J Invest Dermatol 2015 135: 1752-1762; advance online publication, March 3, 2015; 10.1038/jid.2015.63

Large-Scale Electron Microscopy Maps of Patient Skin and Mucosa Provide Insight into Pathogenesis of Blistering Diseases

Ena Sokol, Duco Kramer, Gilles F H Diercks, Jeroen Kuipers, Marcel F Jonkman, Hendri H Pas and Ben N G Giepmans

J Invest Dermatol 2015 135: 1763-1770; advance online publication, March 19, 2015; 10.1038/jid.2015.109

Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences

Olav Sundnes, Wojciech Pietka, Tamara Loos, Jon Sponheim, Andrew L Rankin, Stefan Pflanz, Vibeke Bertelsen, Jan C Sitek, Johanna Hol, Guttorm Haraldsen and Denis Khnykin

J Invest Dermatol 2015 135: 1771-1780; advance online publication, March 4, 2015; 10.1038/jid.2015.85

KERATINOCYTES/EPIDERMIS

Topical Mineralocorticoid Receptor Blockade Limits Glucocorticoid-Induced Epidermal Atrophy in Human Skin

Eve Maubec, Cédric Laouénan, Lydia Deschamps, Van Tuan Nguyen, Isabelle Scheer-Senyarich, Anne-Catherine Wackenheim-Jacobs, Maud Steff, Stéphanie Duhamel, Sarah Tubiana, Nesrine Brahimi, Stéphanie Leclerc-Mercier, Béatrice Crickx, Claudine Perret, Selim Aractingi, Brigitte Escoubet, Xavier Duval, Philippe Arnaud, Frederic Jaisser, France Mentré and Nicolette Farman

J Invest Dermatol 2015 135: 1781-1789; advance online publication, February 10, 2015; 10.1038/jid.2015.44

Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation

Caroline Stremnitzer, Krisztina Manzano-Szalai, Anna Willensdorfer, Philipp Starkl, Mario Pieper, Peter König, Michael Mildner, Erwin Tschachler, Ursula Reichart and Erika Jensen-Jarolim

J Invest Dermatol 2015 135: 1790-1800; advance online publication, February 23, 2015; 10.1038/jid.2015.58

Crystal Structure of Human Profilaggrin S100 Domain and Identification of Target Proteins Annexin II, Stratifin, and HSP27

Christopher G Bunick, Richard B Presland, Owen T Lawrence, David J Pearton, Leonard M Milstone and Thomas A Steitz

J Invest Dermatol 2015 135: 1801-1809; advance online publication, March 11, 2015; 10.1038/jid.2015.102

MELANOCYTES/MELANOMA

Altered E-Cadherin Levels and Distribution in Melanocytes Precede Clinical Manifestations of Vitiligo

Roselyne Y Wagner, Flavie Luciani, Muriel Cario-André, Alain Rubod, Valérie Petit, Laila Benzekri, Khaled Ezzedine, Sébastien Lepreux, Eirikur Steingrimsson, A Taieb, Yvon Gauthier, Lionel Larue and Véronique Delmas

J Invest Dermatol 2015 135: 1810-1819; advance online publication, January 29, 2015; 10.1038/jid.2015.25

Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation

Martin Lauss, Rizwan Haq, Helena Cirenajwis, Bengt Phung, Katja Harbst, Johan Staaf, Frida Rosengren, Karolina Holm, Mattias Aine, Karin Jirström, Åke Borg, Christian Busch, Jürgen Geisler, Per E Lønning, Markus Ringnér, Jillian Howlin, David E Fisher and Göran Jönsson

J Invest Dermatol 2015 135: 1820-1828; advance online publication, February 23, 2015; 10.1038/jid.2015.61

Conditional Deletion of Kit in Melanocytes: White Spotting Phenotype Is Cell Autonomous

Hitomi Aoki, Hiroyuki Tomita, Akira Hara and Takahiro Kunisada

J Invest Dermatol 2015 135: 1829-1838; advance online publication, March 3, 2015; 10.1038/jid.2015.83

NF-κB Regulation of c-FLIP Promotes TNFα-Mediated RAF Inhibitor Resistance in Melanoma

Yongping Shao, Kaitlyn Le, Hanyin Cheng and Andrew E Aplin

J Invest Dermatol 2015 135: 1839-1848; advance online publication, March 9, 2015; 10.1038/jid.2015.91

Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential

Erika M Yazawa, Jenna E Geddes-Sweeney, Filiberto Cedeno-Laurent, Kempland C Walley, Steven R Barthel, Matthew J Opperman, Jennifer Liang, Jennifer Y Lin, Tobias Schatton, Alvaro C Laga, Martin C Mihm, Abrar A Qureshi, Hans R Widlund, George F Murphy and Charles J Dimitroff

J Invest Dermatol 2015 135: 1849-1862; advance online publication, March 10, 2015; 10.1038/jid.2015.95

MITF Modulates Therapeutic Resistance through EGFR Signaling

Zhenyu Ji, Yiyin Erin Chen, Raj Kumar, Michael Taylor, Ching-Ni Jenny Njauw, Benchun Miao, Dennie T Frederick, Jennifer A Wargo, Keith T Flaherty, Göran Jönsson and Hensin Tsao

J Invest Dermatol 2015 135: 1863-1872; advance online publication, March 19, 2015; 10.1038/jid.2015.105

PHOTOBIOLOGY

Elastin Modification by 4-Hydroxynonenal in Hairless Mice Exposed to UV-A. Role in Photoaging and Actinic Elastosis

Pauline Larroque-Cardoso, Caroline Camaré, Florence Nadal-Wollbold, Marie- Hélène Grazide, Mélanie Pucelle, Sandra Garoby-Salom, Patrick Bogdanowicz, Gwendal Josse, Anne-Marie Schmitt, Koji Uchida, Kamelija Zarkovic, Robert Salvayre and Anne Nègre-Salvayre

J Invest Dermatol 2015 135: 1873-1881; advance online publication, March 4, 2015; 10.1038/jid.2015.84

TUMOR BIOLOGY

EphB2 Promotes Progression of Cutaneous Squamous Cell Carcinoma

Mehdi Farshchian, Liisa Nissinen, Elina Siljamäki, Pilvi Riihilä, Mervi Toriseva, Atte Kivisaari, Risto Ala-aho, Markku Kallajoki, Esko Veräjänkorva, Hanne-Kaisa Honkanen, Ritva Heljasvaara, Taina Pihlajaniemi, Reidar Grénman, Juha Peltonen, Sirkku Peltonen and Veli-Matti Kähäri

J Invest Dermatol 2015 135: 1882-1892; advance online publication, March 19, 2015; 10.1038/jid.2015.104

WOUND HEALING

Controlling the Balance of Fibroblast Proliferation and Differentiation: Impact of Thy-1

Manuela Schmidt, Danny Gutknecht, Jan C Simon, Jan-Niklas Schulz, Beate Eckes, Ulf Anderegg and Anja Saalbach

J Invest Dermatol 2015 135: 1893-1902; advance online publication, March 4, 2015; 10.1038/jid.2015.86

Letters to the Editor

Geographical and Temporal Correlations in the Incidence of Lyme Disease, RMSF, Ehrlichiosis, and Coccidioidomycosis with Search Data

Vladimir Ratushny and Gideon P Smith

J Invest Dermatol 2015 135: 1903-1905; advance online publication, March 10, 2015; 10.1038/jid.2015.93

Analysis of CARD14 Polymorphisms in Pityriasis Rubra Pilaris: Activation of NF-κB

Qiaoli Li, Hye Jin Chung, Nicholas Ross, Matthew Keller, Jonathan Andrews, Joshua Kingman, Ofer Sarig, Dana Fuchs-Telem, Eli Sprecher and Jouni Uitto

J Invest Dermatol 2015 135: 1905-1908; advance online publication, March 3, 2015; 10.1038/jid.2015.65

IL-31 Induces Chemotaxis, Calcium Mobilization, Release of Reactive Oxygen Species, and CCL26 in Eosinophils, Which Are Capable to Release IL-31

Nikola Kunsleben, Urda Rüdrich, Manuela Gehring, Natalija Novak, Alexander Kapp and Ulrike Raap

J Invest Dermatol 2015 135: 1908-1911; advance online publication, March 19, 2015; 10.1038/jid.2015.106

Ruxolitinib Attenuates Cutaneous Lupus Development in a Mouse Lupus Model

Emilie S Chan, Leal C Herlitz and Ali Jabbari

J Invest Dermatol 2015 135: 1912-1915; advance online publication, March 19, 2015; 10.1038/jid.2015.107

SIRT1 Activation Ameliorates Aldara-Induced Psoriasiform Phenotype and Histology in Mice

Sijing Xie, Zhonglan Su, Bin Zhang, Jiuyu Ge, Shiyu Song, Guibo Sun, Xiaobo Sun, Long Yi, Yong Wang, Weibin Sun, Hongwei Wang and Qian Gao

J Invest Dermatol 2015 135: 1915-1918; advance online publication, March 3, 2015; 10.1038/jid.2015.82

Loss-of-Function Mutations in the Gene Encoding Filaggrin Are Not Strongly Associated with Chronic Actinic Dermatitis

Catriona P Harkins, Alex Waters, Alastair Kerr, Linda Campbell, W H Irwin McLean, Sara J Brown and Sally H Ibbotson

J Invest Dermatol 2015 135: 1919-1921; advance online publication, March 3, 2015; 10.1038/jid.2015.64

Keloid Pathogenesis: Potential Role of Cellular Fibronectin with the EDA Domain

Jonathan P Andrews, Jaana Marttala, Edward Macarak, Joel Rosenbloom and Jouni Uitto

J Invest Dermatol 2015 135: 1921-1924; advance online publication, February 16, 2015; 10.1038/jid.2015.50

Abstract

2015 Annual Meeting of the Medical Dermatology Society

J Invest Dermatol 2015 135: 1925-1927; 10.1038/jid.2015.143