The EDGE

Martin F. Kagnoff, MD: 1941–2014

K E Barrett, L Eckmann and J M Carethers

Mucosal Immunol. 2015 8: 441-443; 10.1038/mi.2015.8

Reviews

Potential effector and immunoregulatory functions of mast cells in mucosal immunity

L L Reber, R Sibilano, K Mukai and S J Galli

Mucosal Immunol. 2015 8: 444-463; advance online publication, February 11, 2015; 10.1038/mi.2014.131

Eosinophils in mucosal immune responses

J Travers and M E Rothenberg

Mucosal Immunol. 2015 8: 464-475; advance online publication, March 25, 2015; 10.1038/mi.2015.2

Standardised animal models of host microbial mutualism OPEN

A J Macpherson and K D McCoy

Mucosal Immunol. 2015 8: 476-486; advance online publication, December 10, 2014; 10.1038/mi.2014.113

Commentary

Addressing the experimental variability associated with the microbiota

G Eberl

Mucosal Immunol. 2015 8: 487-490; advance online publication, April 8, 2015; 10.1038/mi.2015.26

Articles

TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP

P R de Jong, N Takahashi, M Peiris, S Bertin, J Lee, M G Gareau, A Paniagua, A R Harris, D S Herdman, M Corr, L A Blackshaw and E Raz

Mucosal Immunol. 2015 8: 491-504; advance online publication, October 1, 2014; 10.1038/mi.2014.82

Dual-specificity phosphatase 6 regulates CD4⁺ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice

S Bertin, B Lozano-Ruiz, V Bachiller, I García-Martínez, S Herdman, P Zapater, R Francés, J Such, J Lee, E Raz and J M González-Navajas

Mucosal Immunol. 2015 8: 505-515; advance online publication, September 17, 2014; 10.1038/mi.2014.84

Dendritic cell-bound IgE functions to restrain allergic inflammation at mucosal sites

B Platzer, K Baker, M P Vera, K Singer, M Panduro, W S Lexmond, D Turner, S O Vargas, J-P Kinet, D Maurer, R M Baron, R S Blumberg and E Fiebiger

Mucosal Immunol. 2015 8: 516-532; advance online publication, September 17, 2014; 10.1038/mi.2014.85

Human gastric epithelial cells contribute to gastric immune regulation by providing retinoic acid to dendritic cells

D Bimczok, J Y Kao, M Zhang, S Cochrun, P Mannon, S Peter, C M Wilcox, K E Mönkemüller, P R Harris, J M Grams, R D Stahl, P D Smith and L E Smythies

Mucosal Immunol. 2015 8: 533-544; advance online publication, September 24, 2014; 10.1038/mi.2014.86

A major population of mucosal memory CD4⁺ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality OPEN

P Holmkvist, K Roepstorff, H Uronen-Hansson, C Sandén, S Gudjonsson, O Patschan, O Grip, J Marsal, A Schmidtchen, L Hornum, J S Erjefält, K Håkansson and W W Agace

Mucosal Immunol. 2015 8: 545-558; advance online publication, October 1, 2014; 10.1038/mi.2014.87

Key role for scavenger receptor B-I in the integrative physiology of host defense during bacterial pneumonia

K M Gowdy, J H Madenspacher, K M Azzam, K A Gabor, K S Janardhan, J J Aloor and M B Fessler

Mucosal Immunol. 2015 8: 559-571; advance online publication, October 22, 2014; 10.1038/mi.2014.88

Subversion of human intestinal mucosa innate immunity by a Crohn’s disease-associated E. coli

A Jarry, L Crémet, N Caroff, C Bou-Hanna, J M Mussini, A Reynaud, A L Servin, J F Mosnier, V Liévin-Le Moal and C L Laboisse

Mucosal Immunol. 2015 8: 572-581; advance online publication, October 1, 2014; 10.1038/mi.2014.89

Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23 OPEN

D S Donaldson, B M Bradford, D Artis and N A Mabbott

Mucosal Immunol. 2015 8: 582-595; advance online publication, September 24, 2014; 10.1038/mi.2014.90

Maturation of mast cell progenitors to mucosal mast cells during allergic pulmonary inflammation in mice

L G Bankova, D F Dwyer, A Y Liu, K F Austen and M F Gurish

Mucosal Immunol. 2015 8: 596-606; advance online publication, October 8, 2014; 10.1038/mi.2014.91

A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine

A Dunne, L A Mielke, A C Allen, C E Sutton, R Higgs, C C Cunningham, S C Higgins and K H G Mills

Mucosal Immunol. 2015 8: 607-617; advance online publication, October 15, 2014; 10.1038/mi.2014.93

Dysbiosis caused by vitamin D receptor deficiency confers colonization resistance to Citrobacter rodentium through modulation of innate lymphoid cells

J Chen, A Waddell, Y-D Lin and M T Cantorna

Mucosal Immunol. 2015 8: 618-626; advance online publication, October 15, 2014; 10.1038/mi.2014.94

Protection against Streptococcus pneumoniae lung infection after nasopharyngeal colonization requires both humoral and cellular immune responses OPEN

R Wilson, J M Cohen, R J Jose, C de Vogel, H Baxendale and J S Brown

Mucosal Immunol. 2015 8: 627-639; advance online publication, October 29, 2014; 10.1038/mi.2014.95

Stromal cells as trend-setters for cells migrating into the lymph node

M Buettner, O Dittrich-Breiholz, C S Falk, M Lochner, A Smoczek, F Menzel, M Bornemann and U Bode

Mucosal Immunol. 2015 8: 640-649; advance online publication, November 5, 2014; 10.1038/mi.2014.97

Visualization of the entire differentiation process of murine M cells: suppression of their maturation in cecal patches

S Kimura, M Yamakami-Kimura, Y Obata, K Hase, H Kitamura, H Ohno and T Iwanaga

Mucosal Immunol. 2015 8: 650-660; advance online publication, October 22, 2014; 10.1038/mi.2014.99

Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide OPEN

B O Schroeder, D Ehmann, J C Precht, P A Castillo, R Küchler, J Berger, M Schaller, E F Stange and J Wehkamp

Mucosal Immunol. 2015 8: 661-671; advance online publication, November 5, 2014; 10.1038/mi.2014.100

Conditional IL-4/IL-13-deficient mice reveal a critical role of innate immune cells for protective immunity against gastrointestinal helminths

K Oeser, C Schwartz and D Voehringer

Mucosal Immunol. 2015 8: 672-682; advance online publication, October 22, 2014; 10.1038/mi.2014.101

β-Arrestin2 encourages inflammation-induced epithelial apoptosis through ER stress/PUMA in colitis

L X Zeng, J Tao, H L Liu, S W Tan, Y D Yang, X J Peng, Z H Liu, J Jiang and B Wu

Mucosal Immunol. 2015 8: 683-695; advance online publication, November 5, 2014; 10.1038/mi.2014.104

Letters to the Editor

Response to “In vivo attenuation and genetic evolution of a ST247-SCCmecI MRSA clone after 13 years of pathogenic bronchopulmonary colonization in a patient with cystic fibrosis: implications of the innate immune response”

A Kriegeskorte, D Block and B C Kahl

Mucosal Immunol. 2015 8: 696; advance online publication, February 18, 2015; 10.1038/mi.2015.9

Response to “In vivo attenuation and genetic evolution of a ST247-SCCmecI MRSA clone after 13 years of pathogenic bronchopulmonary colonization in a patient with cystic fibrosis: implications of the innate immune response”

E López-Collazo, T Jurado, J de Dios Caballero, M Pérez-Vázquez, A Vindel, E Hernández-Jiménez, J Tamames, C Cubillos-Zapata, M Manrique, R Tobes, L Máiz, R Cantón, F Baquero and R del Campo

Mucosal Immunol. 2015 8: 697-698; advance online publication, March 4, 2015; 10.1038/mi.2015.10

Erratum

Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis

C M Aherne, B Saeedi, C B Collins, J C Masterson, E N McNamee, L Perrenoud, C R Rapp, V F Curtis, A Bayless, A Fletcher, L E Glover, C M Evans, P Jedlicka, G T Furuta, E F de Zoeten, S P Colgan and H K Eltzschig

Mucosal Immunol. 2015 8: 699; 10.1038/mi.2015.41