Wednesday, May 6, 2015

Molecular Therapy - Table of Contents alert Volume 23 Issue 5

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Molecular Therapy

TABLE OF CONTENTS

Volume 23, Issue 5 (May 2015)

In this issue
Editorial
In This Issue
Research Highlights
Meeting Report
Commentaries
Review
Original Articles

Also new
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Editorial

Top

The Ups and Downs of Clinical Translation of New Technologies: Déjà Vu All Over Again

Paul A Burke

Mol Ther 2015 23: 791-792; 10.1038/mt.2015.51

Full Text

In This Issue

Top

In This Issue

Mol Ther 2015 23: 794; 10.1038/mt.2015.52

Full Text

Research Highlights

Top

Research Highlights

Mol Ther 2015 23: 795; 10.1038/mt.2015.53

Full Text

Meeting Report

Top

Genome Editing Technologies: Defining a Path to Clinic

Jacqueline Corrigan-Curay, Marina O'Reilly, Donald B Kohn, Paula M Cannon, Gang Bao, Frederic D Bushman, Dana Carroll, Toni Cathomen, J Keith Joung, David Roth, Michel Sadelain, Andrew M Scharenberg, Christof von Kalle, Feng Zhang, Robert Jambou, Eugene Rosenthal, Morad Hassani, Aparna Singh and Matthew H Porteus

Mol Ther 2015 23: 796-806; 10.1038/mt.2015.54

Full Text

Commentaries

Top

AAV’s Golden Jubilee

Nicholas Muzyczka and Kenneth I Berns

Mol Ther 2015 23: 807-808; 10.1038/mt.2015.55

Full Text

Moving Forward Toward a Cure for Hemophilia B

Thierry VandenDriessche and Marinee K Chuah

Mol Ther 2015 23: 809-811; 10.1038/mt.2015.56

Full Text

Review

Top

Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications

Sweta Rani, Aideen E Ryan, Matthew D Griffin and Thomas Ritter

Mol Ther 2015 23: 812-823; advance online publication, March 19, 2015; 10.1038/mt.2015.44

Abstract | Full Text

Original Articles

Top

Adenoassociated Virus Serotype 9-Mediated Gene Therapy for X-Linked Adrenoleukodystrophy

Yi Gong, Dakai Mu, Shilpa Prabhakar, Ann Moser, Patricia Musolino, JiaQian Ren, Xandra O Breakefield, Casey A Maguire and Florian S Eichler

Mol Ther 2015 23: 824-834; advance online publication, January 16, 2015; 10.1038/mt.2015.6

Abstract | Full Text

Lentiviral Gene Therapy Using Cellular Promoters Cures Type 1 Gaucher Disease in Mice

Maria Dahl, Alexander Doyle, Karin Olsson, Jan-Eric Månsson, André R A Marques, Mina Mirzaian, Johannes M Aerts, Mats Ehinger, Michael Rothe, Ute Modlich, Axel Schambach and Stefan Karlsson

Mol Ther 2015 23: 835-844; advance online publication, February 6, 2015; 10.1038/mt.2015.16

Abstract | Full Text

Mutated BRAF Emerges as a Major Effector of Recurrence in a Murine Melanoma Model After Treatment With Immunomodulatory Agents

Shane Zaidi, Miran Blanchard, Kevin Shim, Elizabeth Ilett, Karishma Rajani, Christopher Parrish, Nicolas Boisgerault, Tim Kottke, Jill Thompson, Esteban Celis, Jose Pulido, Peter Selby, Hardev Pandha, Alan Melcher, Kevin Harrington and Richard Vile

Mol Ther 2015 23: 845-856; advance online publication, December 29, 2014; 10.1038/mt.2014.253

Abstract | Full Text

Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites

Alyse N Douglass, Heather S Kain, Marian Abdullahi, Nadia Arang, Laura S Austin, Sebastian A Mikolajczak, Zachary P Billman, Jen C C Hume, Sean C Murphy, Stefan H I Kappe and Alexis Kaushansky

Mol Ther 2015 23: 857-865; advance online publication, February 4, 2015; 10.1038/mt.2015.18

Abstract | Full Text

Overcoming Insulin Insufficiency by Forced Follistatin Expression in β-cells of db/db Mice

Chunxia Zhao, Chunping Qiao, Ru-Hang Tang, Jiangang Jiang, Jianbin Li, Carrie Bette Martin, Karen Bulaklak, Juan Li, Dao Wen Wang and Xiao Xiao

Mol Ther 2015 23: 866-874; advance online publication, February 13, 2015; 10.1038/mt.2015.29

Abstract | Full Text

Gene Therapy With the Caspase Activation and Recruitment Domain Reduces the Ocular Inflammatory Response

Cristhian J Ildefonso, Henrique Jaime, Manas R Biswal, Shannon E Boye, Qiuhong Li, William W Hauswirth and Alfred S Lewin

Mol Ther 2015 23: 875-884; advance online publication, February 20, 2015; 10.1038/mt.2015.30

Abstract | Full Text

Proliferation of Multiple Cell Types in the Skeletal Muscle Tissue Elicited by Acute p21 Suppression

Maria Grazia Biferi, Carmine Nicoletti, Germana Falcone, Eleonora M R Puggioni, Nunzia Passaro, Alessia Mazzola, Deborah Pajalunga, Germana Zaccagnini, Emanuele Rizzuto, Alberto Auricchio, Lorena Zentilin, Gabriele De Luca, Mauro Giacca, Fabio Martelli, Antonio Musio, Antonio Musarò and Marco Crescenzi

Mol Ther 2015 23: 885-895; advance online publication, February 11, 2015; 10.1038/mt.2015.27

Abstract | Full Text

Controlled Striatal DOPA Production From a Gene Delivery System in a Rodent Model of Parkinson’s Disease

Erik Cederfjäll, Lauren Broom and Deniz Kirik

Mol Ther 2015 23: 896-906; advance online publication, January 16, 2015; 10.1038/mt.2015.8

Abstract | Full Text

Intracellular Delivery System for Antibody–Peptide Drug Conjugates

Geoffrey Y Berguig, Anthony J Convertine, Shani Frayo, Hanna B Kern, Erik Procko, Debashish Roy, Selvi Srinivasan, Daciana H Margineantu, Garrett Booth, Maria Corinna Palanca-Wessels, David Baker, David Hockenbery, Oliver W Press and Patrick S Stayton

Mol Ther 2015 23: 907-917; advance online publication, February 11, 2015; 10.1038/mt.2015.22

Abstract | Full Text

Repair of Rhodopsin mRNA by Spliceosome-Mediated RNA Trans-Splicing: A New Approach for Autosomal Dominant Retinitis PigmentosaMTOPEN

Adeline Berger, Stéphanie Lorain, Charlène Joséphine, Melissa Desrosiers, Cécile Peccate, Thomas Voit, Luis Garcia, José-Alain Sahel and Alexis-Pierre Bemelmans

Mol Ther 2015 23: 918-930; advance online publication, January 26, 2015; 10.1038/mt.2015.11

Abstract | Full Text

BRAF- and MEK-Targeted Small Molecule Inhibitors Exert Enhanced Antimelanoma Effects in Combination With Oncolytic Reovirus Through ER Stress

Victoria Roulstone, Malin Pedersen, Joan Kyula, David Mansfield, Aadil A Khan, Grainne McEntee, Michelle Wilkinson, Eleni Karapanagiotou, Matt Coffey, Richard Marais, Adel Jebar, Fiona Errington-Mais, Alan Melcher, Richard Vile, Hardev Pandha, Martin McLaughlin and Kevin J Harrington

Mol Ther 2015 23: 931-942; advance online publication, January 26, 2015; 10.1038/mt.2015.15

Abstract | Full Text

Lentivirus-mediated Gene Transfer in Hematopoietic Stem Cells Is Impaired in SHIV-infected, ART-treated Nonhuman Primates

Patrick M Younan, Christopher W Peterson, Patricia Polacino, John P Kowalski, Willimark Obenza, Hannah W Miller, Brian P Milless, Phil Gafken, Stephen C DeRosa, Shiu-Lok Hu and Hans-Peter Kiem

Mol Ther 2015 23: 943-951; advance online publication, February 4, 2015; 10.1038/mt.2015.19

Abstract | Full Text

cAMP and EPAC Signaling Functionally Replace OCT4 During Induced Pluripotent Stem Cell Reprogramming

Ashley L Fritz, Maroof M Adil, Sunnie R Mao and David V Schaffer

Mol Ther 2015 23: 952-963; advance online publication, February 10, 2015; 10.1038/mt.2015.28

Abstract | Full Text

T-cell Subsets in Peripheral Blood and Tumors of Patients Treated With Oncolytic Adenoviruses

Taipale Kristian, Liikanen Ilkka, Juhila Juuso, Karioja-Kallio Aila, Oksanen Minna, Turkki Riku, Linder Nina, Lundin Johan, Ristimäki Ari, Kanerva Anna, Koski Anniina, Joensuu Timo, Vähä-Koskela Markus and Hemminki Akseli

Mol Ther 2015 23: 964-973; advance online publication, February 6, 2015; 10.1038/mt.2015.17

Abstract | Full Text

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