Tuesday, February 24, 2015

Scientific Reports Biology Table of Contents e-alert: 24 February 2015

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  24 February 2015   
 
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Welcome to your Table of Contents e-alert for Scientific Reports

 
 
   
 
 
 
Biological Sciences
 
 
 
 
 
 
 

Fgk3 glycogen synthase kinase is important for development, pathogenesis, and stress responses in Fusarium graminearum

 
 

Jun Qin, Guanghui Wang, Cong Jiang et al.

 
 

Wheat scab caused by Fusarium graminearum is an important disease. In a previous study, the FGK3 glycogen synthase kinase gene orthologous to mammalian GSK3 was identified as an …

 
 
 
 
 
 

Proteins interacting with cloning scars: a source of false positive protein-protein interactions

 
 

Charles A. S. Banks, Gina Boanca, Zachary T. Lee et al.

 
 

A common approach for exploring the interactome, the network of protein-protein interactions in cells, uses a commercially available ORF library to express affinity tagged bait …

 
 
 
 
 
 

Higher-level phylogeny of paraneopteran insects inferred from mitochondrial genome sequences

 
 

Hu Li, Renfu Shao, Nan Song et al.

 
 

Mitochondrial (mt) genome data have been proven to be informative for animal phylogenetic studies but may also suffer from systematic errors, due to the effects of accelerated …

 
 
 
 
 
 

On the Origin of Protein Superfamilies and Superfolds

 
 

Abram Magner, Wojciech Szpankowski, Daisuke Kihara

 
 

Distributions of protein families and folds in genomes are highly skewed, having a small number of prevalent superfamiles/superfolds and a large number of families/folds of a …

 
 
 
 
 
 

Suppression of CYP2C9 by MicroRNA hsa-miR-128-3p in Human Liver Cells and Association with Hepatocellular Carcinoma

 
 

Dianke Yu, Bridgett Green, April Marrone et al.

 
 

Published studies have identified genetic variants, somatic mutations, and changes in gene expression profiles that are associated with hepatocellular carcinoma (HCC), …

 
 
 
 
 
 

Efficient Demyristoylase Activity of SIRT2 Revealed by Kinetic and Structural Studies

 
 

Yan-Bin Teng, Hui Jing, Pornpun Aramsangtienchai et al.

 
 

Sirtuins are a class of enzymes originally identified as nicotinamide adenine dinucleotide (NAD)-dependent protein lysine deacetylases. Among the seven mammalian sirtuins, …

 
 
 
 
 
 

Comparative analysis of KRAS codon 12, 13, 18, 61, and 117 mutations using human MCF10A isogenic cell lines

 
 

Britta Stolze, Stefanie Reinhart, Lars Bulllinger et al.

 
 

KRAS mutations occur in one third of human cancers and cluster in several hotspots, with codons 12 and 13 being most commonly affected. It has been suggested that the position …

 
 
 
 
 
 

Diversity in gut bacterial community of school-age children in Asia

 
 

Jiro Nakayama, Koichi Watanabe, Jiahui Jiang et al.

 
 

Asia differs substantially among and within its regions populated by diverse ethnic groups, which maintain their own respective cultures and dietary habits. To address the …

 
 
 
 
 
 

Bridging topological and functional information in protein interaction networks by short loops profiling

 
 

Sun Sook Chung, Alessandro Pandini, Alessia Annibale et al.

 
 

Protein-protein interaction networks (PPINs) have been employed to identify potential novel interconnections between proteins as well as crucial cellular functions. In this study …

 
 
 
 
 
 

Chromatin compaction under mixed salt conditions: Opposite effects of sodium and potassium ions on nucleosome array folding

 
 

Abdollah Allahverdi, Qinming Chen, Nikolay Korolev et al.

 
 

It is well known that chromatin structure is highly sensitive to the ionic environment. However, the combined effects of a physiologically relevant mixed ionic environment of K, …

 
 
 
 
 
 

Prejudiced interactions: implicit racial bias reduces predictive simulation during joint action with an out-group avatar

 
 

Lucia Maria Sacheli, Andrea Christensen, Martin A. Giese et al.

 
 

During social interactions people automatically apply stereotypes in order to rapidly categorize others. Racial differences are among the most powerful cues that drive these …

 
 
 
 
 
 

Impact of Sox9 Dosage and Hes1-mediated Notch Signaling in Controlling the Plasticity of Adult Pancreatic Duct Cells in Mice

 
 

Shinichi Hosokawa, Kenichiro Furuyama, Masashi Horiguchi et al.

 
 

In the adult pancreas, there has been a long-standing dispute as to whether stem/precursor populations that retain plasticity to differentiate into endocrine or acinar cell types …

 
 
 
 
 
 

Toll-like receptor-2 deficiency induces schizophrenia-like behaviors in mice

 
 

Se Jin Park, Jee Youn Lee, Sang Jeong Kim et al.

 
 

Dysregulation of the immune system contributes to the pathogenesis of neuropsychiatric disorders including schizophrenia. Here, we demonstrated that toll-like receptor (TLR)-2, a …

 
 
 
 
 
 

Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes

 
 

Seiji Yamamoto, Shumpei Niida, Erika Azuma et al.

 
 

Emerging lines of evidence have shown that extracellular vesicles (EVs) mediate cell-to-cell communication by exporting encapsulated materials, such as microRNAs (miRNAs), to …

 
 
 
 
 
 

Neuroinflammation and Aβ Accumulation Linked To Systemic Inflammation Are Decreased By Genetic PKR Down-Regulation

 
 

Anne-Sophie Carret-Rebillat, Clarisse Pace, Sarah Gourmaud et al.

 
 

Alzheimer's disease (AD) is a neurodegenerative disorder, marked by senile plaques composed of amyloid-β (Aβ) peptide, neurofibrillary tangles, neuronal loss and …

 
 
 
 
 
 

No difference in small bowel microbiota between patients with irritable bowel syndrome and healthy controls

 
 

Aldona Dlugosz, Björn Winckler, Elin Lundin et al.

 
 

Several studies have indicated that colonic microbiota may exhibit important differences between patients with irritable bowel syndrome (IBS) and healthy controls. Less is known …

 
 
 
 
 
 

Insights into the Role of Substrates on the Interaction between Cytochrome b5 and Cytochrome P450 2B4 by NMR

 
 

Meng Zhang, Stéphanie V. Le Clair, Rui Huang et al.

 
 

Mammalian cytochrome b5 (cyt b5) is a membrane-bound protein capable of donating an electron to cytochrome P450 (P450) in the P450 catalytic cycle. The interaction between cyt b5

 
 
 
 
 
 

Simultaneous submicrometric 3D imaging of the micro-vascular network and the neuronal system in a mouse spinal cord

 
 

Michela Fratini, Inna Bukreeva, Gaetano Campi et al.

 
 

Faults in vascular (VN) and neuronal networks of spinal cord are responsible for serious neurodegenerative pathologies. Because of inadequate investigation tools, the lacking …

 
 
 
 
 
 

Delay-induced patterns in a two-dimensional lattice of coupled oscillators

 
 

Markus Kantner, Eckehard Schöll, Serhiy Yanchuk

 
 

We show how a variety of stable spatio-temporal periodic patterns can be created in 2D-lattices of coupled oscillators with non-homogeneous coupling delays. The results are …

 
 
 
 
 
 

MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer

 
 

Xiaoqian Yang, Arun K. lyer, Amit Singh et al.

 
 

Development of multidrug resistance (MDR) is an almost universal phenomenon in patients with ovarian cancer, and this severely limits the ultimate success of chemotherapy in the …

 
 
 
 
 
 

Application of IL-36 receptor antagonist weakens CCL20 expression and impairs recovery in the late phase of murine acetaminophen-induced liver injury

 
 

Patrick Scheiermann, Malte Bachmann, Lorena Härdle et al.

 
 

Overdosing of the analgesic acetaminophen (APAP, paracetamol) is a major cause of acute liver injury. Whereas toxicity is initiated by hepatocyte necrosis, course of disease is …

 
 
 
 
 
 

Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner

 
 

Janahan Arulmoli, Medha M. Pathak, Lisa P. McDonnell et al.

 
 

Neural stem and progenitor cell (NSPC) fate is strongly influenced by mechanotransduction as modulation of substrate stiffness affects lineage choice. Other types of mechanical …

 
 
 
 
 
 
 
 
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