TABLE OF CONTENTS
| | | | Volume 135, Issue 1 (January 2015) | | In this issue Editorial Research Techniques Made Simple JID VisualDx Quiz Cells to Surgery Quiz Meeting Report Commentaries Perspective Review Original Articles Letters to the Editor
Also new AOP | | | | | Advertisement | | Milestones in Cutaneous Malignancy
Much of the current cancer lexicon is derived from studies of human or rodent skin. Furthermore, the three major cancer-causing environmental agents, UV light, fossil fuel combustion products, and papilloma viruses, were recognized by astute clinicians and experimental biologists because they produced skin tumors. In fact, clinical observations and experimental studies of skin significantly advanced our understanding of cancer development and progression.
Read more in the Milestones in Cutaneous Malignancy | | | | | | Editorial | Top | | Progress in Translational ResearchBarbara A Gilchrest J Invest Dermatol 2015 135: 1-3; 10.1038/jid.2014.463 Full Text | PDF | | | | Clinical SnippetsJ Invest Dermatol 2015 135: 5; 10.1038/jid.2014.469 Full Text | PDF | | | | Editors' PicksJ Invest Dermatol 2015 135: 6; 10.1038/jid.2014.471 Full Text | PDF | | Research Techniques Made Simple | Top | | Lineage Tracing Mediated by Cre-Recombinase ActivitySusanne Vorhagen, Joanna Jackow, Simona Georgina Mohor, Giel Tanghe, Luna Tanrikulu, Claudia Skazik-Vogt and Frederik Tellkamp J Invest Dermatol 2015 135: e28; 10.1038/jid.2014.472 Full Text | PDF | | JID VisualDx Quiz | Top | | JID VisualDx Quiz: December 2015Arsalan Shabbir and Robert S Kirsner J Invest Dermatol 2015 135: e24; 10.1038/jid.2014.473 Full Text | PDF | | Cells to Surgery Quiz | Top | | Cells to Surgery Quiz: January 2015Leyre Falto-Aizpurua, Brian J Simmons, Robert D Griffith, Mohammad-Ali Yazdani Abyaneh and Keyvan Nouri J Invest Dermatol 2015 135: e9; 10.1038/jid.2014.474 Full Text | PDF | | Meeting Report | Top | | From Pathogenesis, Epidemiology, and Genetics to Definitions, Diagnosis, and Treatments of Cutaneous Lupus Erythematosus and Dermatomyositis: A Report from the 3rd International Conference on Cutaneous Lupus Erythematosus (ICCLE) 2013Heather Y Schultz, Jan P Dutz, Fukumi Furukawa, Mark J Goodfield, Annegret Kuhn, Lela A Lee, Filippa Nyberg, Jacek C Szepietowski, Richard D Sontheimer and Victoria P Werth J Invest Dermatol 2015 135: 7-12; 10.1038/jid.2014.316 Full Text | PDF | | Commentaries | Top | | Omalizumab, an Anti-IgE mAb, Receives Approval for the Treatment of Chronic Idiopathic/Spontaneous UrticariaKeith C P Wu and Zarif K Jabbar-Lopez J Invest Dermatol 2015 135: 13-15; 10.1038/jid.2014.362 Abstract | Full Text | PDF | | | | Comparative Effectiveness of Topical Drugs in Dermatologic Priority Diseases: Geometry of Randomized Trial NetworksChante Karimkhani and Robert P Dellavalle J Invest Dermatol 2015 135: 16-17; 10.1038/jid.2014.380 Abstract | Full Text | PDF | | | | Diagnosis by Numbers: Defining Skin Disease Pathogenesis through Collated Gene SignaturesAmr Salam and John A McGrath J Invest Dermatol 2015 135: 17-19; 10.1038/jid.2014.389 Abstract | Full Text | PDF | | | | Healing Refractory Venous Ulcers: New Treatments Offer HopeRobert S Kirsner, Katherine L Baquerizo Nole, Joshua D Fox and Sophia N Liu J Invest Dermatol 2015 135: 19-23; 10.1038/jid.2014.444 Abstract | Full Text | PDF | | Perspective | Top | | The Harmonizing Outcome Measures for Eczema (HOME) Roadmap: A Methodological Framework to Develop Core Sets of Outcome Measurements in DermatologyJochen Schmitt, Christian Apfelbacher, Phyllis I Spuls, Kim S Thomas, Eric L Simpson, Masutaka Furue, Joanne Chalmers and Hywel C Williams J Invest Dermatol 2015 135: 24-30; advance online publication, September 4, 2014; 10.1038/jid.2014.320 Abstract | Full Text | PDF | | Review | Top | | Immunogenicity of Biotherapy Used in Psoriasis: The Science Behind the ScenesDenis Jullien, Jörg C Prinz and Frank O Nestle J Invest Dermatol 2015 135: 31-38; advance online publication, August 14, 2014; 10.1038/jid.2014.295 Abstract | Full Text | PDF | | Original Articles | Top | | APPENDAGES | Longitudinal, 3D In Vivo Imaging of Sebaceous Glands by Coherent Anti-Stokes Raman Scattering Microscopy: Normal Function and Response to CryotherapyYookyung Jung, Joshua Tam, H Ray Jalian, R Rox Anderson and Conor L Evans J Invest Dermatol 2015 135: 39-44; advance online publication, July 15, 2014; 10.1038/jid.2014.293 Abstract | Full Text | PDF | | | | CD133 Expression Correlates with Membrane Beta-Catenin and E-Cadherin Loss from Human Hair Follicle Placodes during MorphogenesisDenise L Gay, Chao-Chun Yang, Maksim V Plikus, Mayumi Ito, Charlotte Rivera, Elsa Treffeisen, Laura Doherty, Michelle Spata, Sarah E Millar and George Cotsarelis J Invest Dermatol 2015 135: 45-55; advance online publication, July 10, 2014; 10.1038/jid.2014.292 Abstract | Full Text | PDF | | | | CLINICAL RESEARCH | Sleep Disturbances in Adults with Eczema Are Associated with Impaired Overall Health: A US Population-Based StudyJonathan I Silverberg, Nitin K Garg, Amy S Paller, Anna B Fishbein and Phyllis C Zee J Invest Dermatol 2015 135: 56-66; advance online publication, August 31, 2014; 10.1038/jid.2014.325 Abstract | Full Text | PDF | | | | Efficacy and Safety of Omalizumab in Patients with Chronic Idiopathic/Spontaneous Urticaria Who Remain Symptomatic on H1 Antihistamines: A Randomized, Placebo-Controlled StudyJIDOPENSarbjit S Saini, Carsten Bindslev-Jensen, Marcus Maurer, Jean-Jacques Grob, Emel Bülbül Baskan, Mary S Bradley, Janice Canvin, Abdelkader Rahmaoui, Panayiotis Georgiou, Oral Alpan, Sheldon Spector and Karin Rosén J Invest Dermatol 2015 135: 67-75; advance online publication, July 21, 2014; 10.1038/jid.2014.306 Abstract | Full Text | PDF | | | | EPIDEMIOLOGY | Comparative Effectiveness of Topical Drugs in Dermatologic Priority Diseases: Geometry of Randomized Trial NetworksAnnabel Maruani, Mahtab Samimi, Gérard Lorette and Laurence le Cleach J Invest Dermatol 2015 135: 76-83; advance online publication, June 21, 2014; 10.1038/jid.2014.296 Abstract | Full Text | PDF | | | | IMMUNOLOGY/INFECTION | The Skin Immune Atlas: Three-Dimensional Analysis of Cutaneous Leukocyte Subsets by Multiphoton MicroscopyPhilip L Tong, Ben Roediger, Natasha Kolesnikoff, Maté Biro, Szun S Tay, Rohit Jain, Lisa E Shaw, Michele A Grimbaldeston and Wolfgang Weninger J Invest Dermatol 2015 135: 84-93; advance online publication, August 9, 2014; 10.1038/jid.2014.289 Abstract | Full Text | PDF | | | | Genomic Profiling of Human Leishmania braziliensis Lesions Identifies Transcriptional Modules Associated with Cutaneous ImmunopathologyFernanda O Novais, Lucas P Carvalho, Sara Passos, David S Roos, Edgar M Carvalho, Phillip Scott and Daniel P Beiting J Invest Dermatol 2015 135: 94-101; advance online publication, July 18, 2014; 10.1038/jid.2014.305 Abstract | Full Text | PDF | | | | Der p 11 Is a Major Allergen for House Dust Mite-Allergic Patients Suffering from Atopic DermatitisSrinita Banerjee, Yvonne Resch, Kuan-Wei Chen, Ines Swoboda, Margit Focke-Tejkl, Katharina Blatt, Natalija Novak, Magnus Wickman, Marianne van Hage, Rosetta Ferrara, Adriano Mari, Ashok Purohit, Gabrielle Pauli, Elopy N Sibanda, Portia Ndlovu, Wayne R Thomas, Vladislav Krzyzanek, Sebastian Tacke, Ursula Malkus, Peter Valent, Rudolf Valenta and Susanne Vrtala J Invest Dermatol 2015 135: 102-109; advance online publication, August 7, 2014; 10.1038/jid.2014.271 Abstract | Full Text | PDF | | | | Propionibacterium acnes Promotes Th17 and Th17/Th1 Responses in Acne PatientsMagdalena Kistowska, Barbara Meier, Tatiana Proust, Laurence Feldmeyer, Antonio Cozzio, Thomas Kuendig, Emmanuel Contassot and Lars E French J Invest Dermatol 2015 135: 110-118; advance online publication, July 10, 2014; 10.1038/jid.2014.290 Abstract | Full Text | PDF | | | | The Late Endosomal Adaptor Molecule p14 (LAMTOR2) Regulates TGFβ1-Mediated Homeostasis of Langerhans CellsFlorian Sparber, Christoph H Tripp, Kerstin Komenda, Julia M Scheffler, Björn E Clausen, Lukas A Huber, Nikolaus Romani and Patrizia Stoitzner J Invest Dermatol 2015 135: 119-129; advance online publication, July 31, 2014; 10.1038/jid.2014.324 Abstract | Full Text | PDF | | | | CD90+ Human Dermal Stromal Cells Are Potent Inducers of FoxP3+ Regulatory T CellsKarin Pfisterer, Karoline M Lipnik, Erhard Hofer and Adelheid Elbe-Bürger J Invest Dermatol 2015 135: 130-141; advance online publication, July 22, 2014; 10.1038/jid.2014.309 Abstract | Full Text | PDF | | | | Vaccinia Virus Binds to the Scavenger Receptor MARCO on the Surface of KeratinocytesDaniel T MacLeod, Teruaki Nakatsuji, Zhenping Wang, Anna di Nardo and Richard L Gallo J Invest Dermatol 2015 135: 142-150; advance online publication, August 4, 2014; 10.1038/jid.2014.330 Abstract | Full Text | PDF | | | | Comparison of Molecular Signatures from Multiple Skin Diseases Identifies Mechanisms of ImmunopathogenesisMegan S Inkeles, Philip O Scumpia, William R Swindell, David Lopez, Rosane M B Teles, Thomas G Graeber, Stephan Meller, Bernhard Homey, James T Elder, Michel Gilliet, Robert L Modlin and Matteo Pellegrini J Invest Dermatol 2015 135: 151-159; advance online publication, August 11, 2014; 10.1038/jid.2014.352 Abstract | Full Text | PDF | | | | SERPINB3/B4 Contributes to Early Inflammation and Barrier Dysfunction in an Experimental Murine Model of Atopic DermatitisUmasundari Sivaprasad, Kayla G Kinker, Mark B Ericksen, Mark Lindsey, Aaron M Gibson, Stacey A Bass, Nicolas S Hershey, Jingyuan Deng, Mario Medvedovic and Gurjit K Khurana Hershey J Invest Dermatol 2015 135: 160-169; advance online publication, August 11, 2014; 10.1038/jid.2014.353 Abstract | Full Text | PDF | | | | KERATINOCYTES/EPIDERMIS | Suppressing AP1 Factor Signaling in the Suprabasal Epidermis Produces a Keratoderma PhenotypeEllen A Rorke, Gautam Adhikary, Christina A Young, Dennis R Roop and Richard L Eckert J Invest Dermatol 2015 135: 170-180; advance online publication, August 22, 2014; 10.1038/jid.2014.310 Abstract | Full Text | PDF | | | | Requirement of Gαi1/3–Gab1 Signaling Complex for Keratinocyte Growth Factor–Induced PI3K–AKT–mTORC1 ActivationYi-ming Zhang, Zhi-qing Zhang, Yuan-yuan Liu, Xin Zhou, Xiao-hua Shi, Qin Jiang, Dong-li Fan and Cong Cao J Invest Dermatol 2015 135: 181-191; advance online publication, July 31, 2014; 10.1038/jid.2014.326 Abstract | Full Text | PDF | | | | POF1B Localizes to Desmosomes and Regulates Cell Adhesion in Human Intestinal and Keratinocyte Cell LinesArianna Crespi, Alessandra Bertoni, Ilaria Ferrari, Valeria Padovano, Pamela Della Mina, Emilio Berti, Antonello Villa and Grazia Pietrini J Invest Dermatol 2015 135: 192-201; advance online publication, August 1, 2014; 10.1038/jid.2014.327 Abstract | Full Text | PDF | | | | MELANOCYTES/MELANOMA | Melanocytic Galectin-3 Is Associated with Tyrosinase-Related Protein-1 and Pigment BiosynthesisAllison Chalupa, Amy Koshoffer, Emily Galan, Lan Yu, Fu-Tong Liu and Raymond E Boissy J Invest Dermatol 2015 135: 202-211; advance online publication, July 23, 2014; 10.1038/jid.2014.315 Abstract | Full Text | PDF | | | | Activin A Is Anti-Lymphangiogenic in a Melanoma Mouse ModelMagdalena Heinz, Heide Leb Niederleithner, Emmi Puujalka, Ana Soler-Cardona, Michael Grusch, Hubert Pehamberger, Robert Loewe and Peter Petzelbauer J Invest Dermatol 2015 135: 212-221; advance online publication, August 1, 2014; 10.1038/jid.2014.328 Abstract | Full Text | PDF | | | | PHOTOBIOLOGY | Basophil-Derived Amphiregulin Is Essential for UVB Irradiation–Induced Immune SuppressionChantal Meulenbroeks, Huib van Weelden, Christian Schwartz, David Voehringer, Frank A M Redegeld, Victor P M G Rutten, Ton Willemse, Alice J A M Sijts and Dietmar M W Zaiss J Invest Dermatol 2015 135: 222-228; advance online publication, July 4, 2014; 10.1038/jid.2014.329 Abstract | Full Text | PDF | | | | TUMOR BIOLOGY | KIR3DL2/CpG ODN Interaction Mediates Sézary Syndrome Malignant T Cell ApoptosisBouchra Ghazi, Nicolas Thonnart, Martine Bagot, Armand Bensussan and Anne Marie-Cardine J Invest Dermatol 2015 135: 229-237; advance online publication, July 9, 2014; 10.1038/jid.2014.286 Abstract | Full Text | PDF | | | | Malignant T Cells Secrete Galectins and Induce Epidermal Hyperproliferation and Disorganized Stratification in a Skin Model of Cutaneous T-Cell LymphomaChristenze Thode, Anders Woetmann, Hans H Wandall, Michael C Carlsson, Klaus Qvortrup, Claudia S Kauczok, Marion Wobser, Andreas Printzlau, Niels Ødum and Sally Dabelsteen J Invest Dermatol 2015 135: 238-246; advance online publication, July 9, 2014; 10.1038/jid.2014.284 Abstract | Full Text | PDF | | | | CD158k Is a Reliable Marker for Diagnosis of Sézary Syndrome and Reveals an Unprecedented Heterogeneity of Circulating Malignant CellsHélène Moins-Teisserenc, Magali Daubord, Emmanuel Clave, Corinne Douay, Joana Félix, Anne Marie-Cardine, Caroline Ram-Wolff, Guitta Maki, Kheira Beldjord, Laurence Homyrda, Laurence Michel, Armand Bensussan, Antoine Toubert and Martine Bagot J Invest Dermatol 2015 135: 247-257; advance online publication, August 26, 2014; 10.1038/jid.2014.356 Abstract | Full Text | PDF | | | | WOUND HEALING | Galectin-1 Accelerates Wound Healing by Regulating the Neuropilin-1/Smad3/NOX4 Pathway and ROS Production in MyofibroblastsYueh-Te Lin, Jhih-Sian Chen, Ming-Heng Wu, I-Shan Hsieh, Chen-Hsien Liang, Cheng-Lung Hsu, Tse-Ming Hong and Yuh-Ling Chen J Invest Dermatol 2015 135: 258-268; advance online publication, July 9, 2014; 10.1038/jid.2014.288 Abstract | Full Text | PDF | | | | Proinsulin C-Peptide Prevents Impaired Wound Healing by Activating Angiogenesis in DiabetesYoung-Cheol Lim, Mahendra Prasad Bhatt, Mi-Hye Kwon, Donghyun Park, SungHun Na, Young-Myeong Kim and Kwon-Soo Ha J Invest Dermatol 2015 135: 269-278; advance online publication, July 9, 2014; 10.1038/jid.2014.285 Abstract | Full Text | PDF | | | | β2-Adrenoceptor Activation Modulates Skin Wound Healing Processes to Reduce ScarringJIDOPENGabrielle S Le Provost and Christine E Pullar J Invest Dermatol 2015 135: 279-288; advance online publication, July 22, 2014; 10.1038/jid.2014.312 Abstract | Full Text | PDF | | | | The Effect of a Connexin43-Based Peptide on the Healing of Chronic Venous Leg Ulcers: A Multicenter, Randomized TrialJIDOPENGautam S Ghatnekar, Christina L Grek, David G Armstrong, Sanjay C Desai and Robert G Gourdie J Invest Dermatol 2015 135: 289-298; advance online publication, July 29, 2014; 10.1038/jid.2014.318 Abstract | Full Text | PDF | | Letters to the Editor | Top | | Epidermal Stem Cells in the Isthmus/Infundibulum Influence Hair Shaft Differentiation: Evidence from Targeted DLX3 DeletionJin-Chul Kim, Olivier Duverger, Joonsung Hwang and Maria I Morasso J Invest Dermatol 2015 135: 299-301; advance online publication, July 9, 2014; 10.1038/jid.2014.287 Full Text | PDF | | | | Talaporfin Sodium–Mediated Photodynamic Therapy Alone and in Combination with Pulsed Dye Laser on Cutaneous VasculatureKristen M Kelly, Wesley J Moy, Austin J Moy, Ben S Lertsakdadet, Justin J Moy, Elaine Nguyen, Ashley Nguyen, Kathryn E Osann and Bernard Choi J Invest Dermatol 2015 135: 302-304; advance online publication, July 18, 2014; 10.1038/jid.2014.304 Full Text | PDF | | | | Multiple Self-Healing Palmoplantar Carcinoma: A Familial Predisposition to Skin Cancer with Primary Palmoplantar and Conjunctival LesionsJIDOPENOns Mamaï, Lobna Boussofara, Mohamed Denguezli, Nathalie Escande-Beillard, Wahiba Kraeim, Barry Merriman, Ilhem Ben Charfeddine, Giovanni Stevanin, Sana Bouraoui, Abdelbasset Amara, Amira Mili, Rafiaa Nouira, Dorra H'mida, Badreddine Sriha, Moez Gribaa, Ali Saad and Bruno Reversade J Invest Dermatol 2015 135: 304-308; advance online publication, July 22, 2014; 10.1038/jid.2014.311 Full Text | PDF | | | | Disease Control in Cutaneous Leishmaniasis Is Independent of IL-22Sven Brosch, Kirsten Dietze-Schwonberg, Susanna Lopez Kostka, Beate Lorenz, Stefan Haak, Burkhard Becher and Esther von Stebut J Invest Dermatol 2015 135: 308-311; advance online publication, July 7, 2014; 10.1038/jid.2014.282 Full Text | PDF | | | | IL-17A Production in Human Psoriatic Blood and Lesions by CD146+ T CellsNehal N Mehta, Pradeep K Dagur, Shawn M Rose, Haley B Naik, Elena Stansky, Julia Doveikis, Angelique Biancotto, Martin P Playford and J Philip McCoy, Jr J Invest Dermatol 2015 135: 311-314; advance online publication, July 24, 2014; 10.1038/jid.2014.317 Full Text | PDF | | | | A Rac1-Independent Role for P-Rex1 in MelanoblastsJIDOPENColin R Lindsay, Ang Li, William Faller, Brad Ozanne, Heidi Welch, Laura M Machesky and Owen J Sansom J Invest Dermatol 2015 135: 314-318; advance online publication, July 30, 2014; 10.1038/jid.2014.323 Full Text | PDF | | | | Rationale for the Development of Speckled Hyperpigmentation in the Areas of Psoriatic Plaques after Treatment with Biologic AgentsAntonella Di Cesare, Maria Concetta Fargnoli, Alessandro Marinucci and Ketty Peris J Invest Dermatol 2015 135: 318-320; advance online publication, July 18, 2014; 10.1038/jid.2014.297 Full Text | PDF | | | | Topical Photodynamic Therapy Induces Systemic Immunosuppression via Generation of Platelet-Activating Factor Receptor LigandsMatheus Ferracini, Ravi P Sahu, Kathleen A Harrison, Robert A Waeiss, Robert C Murphy, Sonia Jancar, Raymond L Konger and Jeffrey B Travers J Invest Dermatol 2015 135: 321-323; advance online publication, July 22, 2014; 10.1038/jid.2014.313 Full Text | PDF | | | | | Advertisement | |
Nature Outlook Melanoma
Melanoma — the deadliest form of skin cancer — is on the rise in many parts of the world. But new treatments, and efforts to tell people how to prevent it, could mean we will soon gain the upper hand on the disease. Access the Outlook free online for six months.
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